Lofebril 100 Tablet

Reviewed By Dr. Varun Gupta, MD Pharmacology, MBBS

Last updated on 09 Nov 2024 | 01:07 AM (IST)

Lofebril 100 Tablet is a type of antidepressant belonging to the selective serotonin reuptake inhibitor (SSRI) group of medicines. It is prescribed to treat depression, where it helps to make you feel better. This medicine is also used to treat people with obsessive-compulsive disorder.

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1/2

10 tablets

General Information

Contains

Fluvoxamine (100mg)

Marketer

Dycine Pharmaceuticals Ltd

Storage

Store below 30°C

The content is shown in English

Product introduction

Lofebril 100 Tablet can be taken with or without food. The dose and how often you need it will be decided by your doctor so that you get the right amount to control your symptoms. Your doctor may start you on a lower dose and increase it gradually. Do not change the dose or stop taking it without talking to your doctor, even if you feel well. Doing so may make your condition worse or you may suffer from unpleasant withdrawal symptoms (anxiety, restlessness, palpitations, dizziness, sleep disturbances, etc).

To get the most benefit, take this medicine regularly at the same time each day. It may take a few weeks before you start feeling better. Let your doctor know if you do not see any improvement even after 4 weeks.

Lofebril 100 Tablet has been reported to have fewer side effects than older antidepressants. Some common side effects of this medicine include nausea, vomiting, fatigue, dry mouth, increased sweating, tremors, insomnia (difficulty in sleeping), decreased sexual drive, delayed ejaculation, and erectile dysfunction. Some people may experience sleepiness after taking this medicine. Let your doctor know if you develop any sudden worsening of mood or any thoughts about harming yourself.

Before taking this medicine, you should tell your doctor if you have epilepsy (seizure disorder or fits), diabetes, liver or kidney disease, heart problems, or glaucoma. These may affect your treatment. Pregnant or breastfeeding women should also consult their doctor before taking it. Some other medicines may affect the way it works, especially other antidepressants and medicines called MAO inhibitors. Please tell your doctor about all the medicines you are taking to make sure you are safe.

Uses of Lofebril Tablet

Benefits of Lofebril Tablet

Depression
Lofebril 100 Tablet works by increasing the level of a chemical called serotonin in the brain. This improves your mood, relieves anxiety, tension, and helps you sleep better. It has fewer side effects than older antidepressants. It usually takes 4-6 weeks for this medicine to work so you need to keep taking it even if you feel it is not working. Do not stop taking it, even if you feel better unless your doctor advises you to.

Obsessive-compulsive disorder
Lofebril 100 Tablet helps relieve symptoms of many anxiety disorders such as obsessive-compulsive disorder by increasing the level of a chemical called serotonin in your brain. It has fewer side effects than older antidepressants and is normally taken once a day. It helps you feel calm with a better ability to deal with problems. Exercise and a healthy diet can also improve your mood. Keep taking the medicine until your doctor advises you to stop.

Side effects of Lofebril Tablet

Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them

Common side effects of Lofebril

Delayed ejaculation
Drowsiness
Erectile dysfunction
Low sexual desire
Nausea
Vomiting
Dryness in mouth
Fatigue
Increased sweating
Indigestion
Insomnia (difficulty in sleeping)
Loss of appetite
Nervousness
Tremors

How to use Lofebril Tablet

Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Lofebril 100 Tablet may be taken with or without food, but it is better to take it at a fixed time.

How Lofebril Tablet works

Lofebril 100 Tablet is a selective serotonin reuptake inhibitor (SSRI) antidepressant. It works by increasing the levels of serotonin, a chemical messenger in the brain. This improves mood and physical symptoms of depression and also relieves symptoms of obsessive-compulsive disorders.

All substitutes for Lofebril 100 Tablet

For information purposes only. Consult a doctor before taking any medicine.

Quick tips

It should be taken at night with or without food.
Take caution while taking Lofebril 100 Tablet if you are using Benzodiazepines and MAO inhibitors previously.
Do not drive or do anything requiring concentration until you know how Lofebril 100 Tablet affects you.
Talk to your doctor if you notice sudden mood changes or develop suicidal thoughts.
Do not stop taking the medication suddenly without talking to your doctor.

Safety advice

Alcohol

UNSAFE

It is unsafe to consume alcohol with Lofebril 100 Tablet.

Pregnancy

CONSULT YOUR DOCTOR

Lofebril 100 Tablet may be unsafe to use during pregnancy. Although there are limited studies in humans, animal studies have shown harmful effects on the developing baby. Your doctor will weigh the benefits and any potential risks before prescribing it to you. Please consult your doctor.

Breast feeding

CONSULT YOUR DOCTOR

Lofebril 100 Tablet is probably unsafe to use during breastfeeding. Limited human data suggests that the drug may pass into the breastmilk and harm the baby.

Driving

SAFE

Lofebril 100 Tablet does not usually affect your ability to drive.

Kidney

CAUTION

Lofebril 100 Tablet should be used with caution in patients with severe kidney disease. Dose adjustment of Lofebril 100 Tablet may be needed. Please consult your doctor.

Liver

CAUTION

Lofebril 100 Tablet should be used with caution in patients with liver disease. Dose adjustment of Lofebril 100 Tablet may be needed. Please consult your doctor.

Frequently asked questions

Is Lofebril 100 Tablet used for anxiety?

Yes, Lofebril 100 Tablet is used to treat social anxiety disorder. It is anxiety related to interacting with others or performing in front of others that interferes with normal life. Lofebril 100 Tablet is also used for the treatment of the obsessive-compulsive disorder (OCD) and panic attacks. In OCD, a person experiences unwanted thoughts and the irresistible desire to perform certain actions over and over. These thoughts and desires do not go away and make it bothersome for the person.

Can Lofebril 100 Tablet get you high?

There is no evidence that Lofebril 100 Tablet causes dependence. But, patients may experience withdrawal symptoms on sudden discontinuation of Lofebril 100 Tablet. Usually, the withdrawal symptoms are mild and go away on their own within 2 weeks.

Who should not take Lofebril 100 Tablet?

You should not take Lofebril 100 Tablet if you are allergic to it, if you are taking another medicine to treat depression called a Monoamine Oxidase Inhibitor (MAOI), or if you have stopped taking an MAOI within the last 14 days. This is because taking both these medicines close in time together may cause serious and sometimes fatal reactions like high body temperature, convulsions, and even coma.

Does Lofebril 100 Tablet make you sleepy?

Yes, a common side effect of Lofebril 100 Tablet is sleepiness. It may also affect your ability to think clearly, make decisions, or react quickly. Avoid driving or operating heavy machinery until and unless you know how Lofebril 100 Tablet affects you.

Does Lofebril 100 Tablet have any serious health risks associated with it?

Yes, the use of Lofebril 100 Tablet may cause serious health risks. These may include increased risks of suicidal thoughts and actions, mania, bleeding problems, convulsions, visual problems, and low sodium levels in the blood.

How quickly does Lofebril 100 Tablet work?

It takes a long time for Lofebril 100 Tablet to start working. However, you may see an improvement in your sleep, appetite and energy levels within 1-2 weeks of starting Lofebril 100 Tablet. While, conditions like depressed mood and lack of interest in activities may take about 6-8 weeks to improve.

Can I stop Lofebril 100 Tablet if I am better now?

No, instead of stopping the medicine by yourself, consult your doctor who will gradually reduce the dose before stopping it completely. This is done because sudden discontinuation of Lofebril 100 Tablet may cause withdrawal symptoms. These symptoms include anxiety, irritability, high or low mood, feeling restless or changes in sleep habits, headache, sweating, nausea, dizziness, electric shock-like sensations, shaking, and confusion.

Does Lofebril 100 Tablet cause weight gain?

Lofebril 100 Tablet may either cause weight gain or weight loss. The weight loss could be due to loss of appetite. However, the chances of having weight gain or loss is not known. As compared to other anti-depressants, there is no significant change in body weight with Lofebril 100 Tablet in the majority of people.

Fact Box

Chemical Class

Aralkylketone Derivative

Habit Forming

Therapeutic Class

NEURO CNS

Action Class

Selective Seretonin Reuptake inhibitors (SSRIs)

References

Stahl SM, editor. Fluvoxamine. In: Stahl's Essential Pschopharmacology: Prescriber's Guide. 5th ed. New York, New York: Cambridge University Press; 2014. pp. 269-74.
Briggs GG, Freeman RK, editors. A Reference Guide to Fetal and Neonatal Risk: Drugs in Pregnancy and Lactation. 10th ed. Philadelphia, PA: Wolters Kluwer Health; 2015. pp. 578-81.
Fluvoxamine maleate. Jazz Pharmaceuticals; 1994 [revised 2008]. [Accessed 25 Mar. 2019] (online) Available from:
Chaves RG, Lamounier JA. Breastfeeding and maternal medications. J Pediatr (Rio J). 2004;80(5 Suppl):S189-S198. [Accessed 20 Mar. 2019] (online) Available from:
Central Drugs Standard Control Organisation (CDSCO). [Accessed 25 Mar. 2019] (online) Available from:
Fluvoxamine Tablets [Package Insert]. Ahmedabad, Gujarat: Torrent Pharmaceuticals Ltd.; 2014. [Accessed 03 Jul. 2023] (online) Available from:
Fluvoxamine maleate [Product Information]. Millers Point, NSW: Viatris Pty Ltd.; 2023. [Accessed 03 Jul. 2023] (online) Available from:

Patient concerns

I have Obsessive compulsive Disorder. Prescribe the medication.

Dr. Deepak Kumar Soni

Ayurveda

Hi Kindly share your symptoms of your Problem

Sir, I wont to take best medicine of Ayurveda for obsessive compulsive disorders(Depression)

Dr. Ankur Kumar Tanwar

Ayurveda

Use brahmi granules and jatamansi vati ,

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Marketer details

Name: Dycine Pharmaceuticals Ltd
Address: 381 Bolck III, Ganga Shopping Complex, Sector 29, NOIDA-201 301

Vendor Details

Country of origin: India
A licensed vendor partner from your nearest location will deliver Lofebril 100 Tablet. Once the pharmacy accepts your order, the details of the pharmacy will be shared with you. Acceptance of your order is based on the validity of your doctor's ℞ and the availability of this medicine.

In case of any issues, contact us

Email ID: [email protected]
Phone Number: 0124-4166666
Address: 5th Floor Tower - B of the Presidency Building, 46/4 Mehrauli Gurgaon Road, Sector 14, Gurugram, Haryana-122001, India

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