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Lorazen Injection

Written By Dr. Love Sharma, PhD (Pharmacology), PGDPRA
Reviewed By Dr. Khushbu Goel, DM, MD
Last updated on 12 Nov 2024 | 01:00 AM (IST)
Lorazen Injection is a prescription medicine used to treat status epilepticus. A medical emergency when a prolonged seizure occurs or continuous seizure occurs within a span of five minutes, even before the person recovers from the previous one.
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General Information

Contains

Lorazepam (2mg)

Marketer

Zenith Healthcare Ltd

Storage

Store in a refrigerator (2 - 8°C). Do not freeze.
The content is shown in English
Lorazen Injection image

Product introduction

Lorazen Injection may also be used to induce anesthesia before an investigation or a surgical procedure. It relieves anxiety and muscle tension, thus making the person comfortable before the operation or investigation procedure. This medicine is given as an injection under the supervision of a healthcare professional. Lorazen Injection may be given into your vein (intravenously) or into one of your muscles (intramuscularly). The recommended dose depends on your age, weight and why it is being used for you. It is usually used for a short-term only owing to its high habit-forming potential.

Side effects of this medicine include drowsiness, sedation, tiredness, confusion, depression, muscle weakness. It may also cause dizziness and sleepiness, so do not drive or do anything that requires mental focus until you know how this medicine affects you. It is important to inform your doctor if you are pregnant, planning to conceive, or breastfeeding before taking this medicine.

Uses of Lorazen Injection

Benefits of Lorazen Injection

Treatment of Status epilepticus
Status epilepticus is when a seizure lasts longer than 5 minutes or when seizures occur close together and the person doesn't recover between seizures. It is a medical emergency and needs immediate medical attention. Lorazen Injection slows down electrical signals in the brain which cause seizures (fits). It can also help reduce symptoms such as confusion, uncontrollable jerking movements, loss of awareness, and fear or anxiety. It is given as an injection by a doctor or nurse.
Treatment of Anxiety disorder
Lorazen Injection helps relieve symptoms of many anxiety disorders including obsessive-compulsive disorder and generalised anxiety disorder by increasing the level of a chemical called GABA in your brain. This prevents abnormal symptoms of anxiety such as restlessness, tiredness, difficulty concentrating, feeling irritable and sleep problems. It helps you feel calm with a better ability to deal with problems. Exercise and a healthy diet can also improve your mood. Keep taking the medicine until your doctor advises you to stop.
Treatment of Short term anxiety
Lorazen Injection reduces the symptoms of excessive anxiety and worry that may arise in stressful conditions such as an exam or job interview. It can also reduce feelings of restlessness, tiredness, difficulty concentrating and feeling irritable. This will therefore help you go about your daily activities more easily and be more productive. Keep taking this medicine even if you feel well. Stopping suddenly can cause serious problems.

Side effects of Lorazen Injection

Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them
Common side effects of Lorazen
  • Injection site pain
  • Sedation
  • Dizziness
  • Fatigue
  • Muscle weakness
  • Drowsiness

How to use Lorazen Injection

Your doctor or nurse will give you this medicine. Kindly do not self administer.

How Lorazen Injection works

Lorazen Injection is a benzodiazepine. It works by increasing the action of a chemical messenger (GABA) which suppresses the abnormal and excessive activity of the nerve cells in the brain.

Quick tips

  • The addiction / habit-forming potential of this medicine is very high. Take it only as per the dose and duration advised by your doctor
  • It may cause dizziness. Do not drive or do anything that requires mental focus until you know how this medicine affects you.
  • Avoid consuming alcohol as it may increase dizziness and drowsiness.
  • Inform your doctor if you are pregnant, planning to conceive or breastfeeding.
  • Do not stop taking medication suddenly without talking to your doctor as that may lead to nausea, anxiety, agitation, flu-like symptoms, sweating, tremor, and confusion.
  • The addiction / habit-forming potential of this medicine is very high. Take it only as per the dose and duration advised by your doctor
  • It may cause dizziness. Do not drive or do anything that requires mental focus until you know how this medicine affects you.
  • Avoid consuming alcohol as it may increase dizziness and drowsiness.
  • Inform your doctor if you are pregnant, planning to conceive or breastfeeding.
  • Do not stop taking medication suddenly without talking to your doctor as that may lead to nausea, anxiety, agitation, flu-like symptoms, sweating, tremor, and confusion.

Safety advice

Alcohol

Alcohol

UNSAFE
It is unsafe to consume alcohol with Lorazen Injection.
Pregnancy

Pregnancy

CONSULT YOUR DOCTOR
Lorazen Injection is unsafe to use during pregnancy as there is definite evidence of risk to the developing baby. However, the doctor may rarely prescribe it in some life-threatening situations if the benefits are more than the potential risks. Please consult your doctor.
Breast feeding

Breast feeding

CONSULT YOUR DOCTOR
Lorazen Injection is probably unsafe to use during breastfeeding. Limited human data suggests that the drug may pass into the breastmilk and harm the baby.
Lorazen Injection should be used for short periods and sleepiness of the baby should be watched. The withdrawal of Lorazen Injection should be gradual.
Driving

Driving

UNSAFE
Lorazen Injection may decrease alertness, affect your vision or make you feel sleepy and dizzy. Do not drive if these symptoms occur.
Kidney

Kidney

CAUTION
Lorazen Injection should be used with caution in patients with severe kidney disease. Dose adjustment of Lorazen Injection may be needed. Please consult your doctor.
However, inform your doctor if you have any underlying kidney disease.
Liver

Liver

CAUTION
Lorazen Injection should be used with caution in patients with severe liver disease. Dose adjustment of Lorazen Injection may be needed. Please consult your doctor.
Use of Lorazen Injection is not recommended in patients with severe liver disease.
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Frequently asked questions

No, Lorazen Injection is not an opioid. It belongs to the benzodiazepine group of medicines and is used for short-term treatment (2-4 weeks) only. It is a habit-forming medicine and can make a person physically and psychologically dependent.
Lorazen Injection may take around 3 days to get completely removed from the system.
The most important symptom of addiction is that you may feel unpleasant if you do not take Lorazen Injection. Another symptom could be that you may increase the dose on your own to feel its effect.
You should reduce the dose of Lorazen Injection gradually before completely stopping it. Suddenly stopping it may lead to withdrawal symptoms which include loss of the sense of reality, feeling detached from life, and unable to feel emotion. Some patients have also experienced numbness or tingling in the arms or legs, tinnitus (ringing sounds in the ears), uncontrolled or overactive movements, twitching, shaking, feeling sick, being sick, stomach upsets or stomach pain, loss of appetite, agitation and abnormally fast heart beats. It can also cause panic attacks, dizziness or feeling faint, memory loss, hallucinations, feeling stiff and unable to move easily, feeling very warm, convulsions (sudden uncontrolled shaking or jerking of the body) and oversensitivity to light, sound and touch.
The effect of Lorazen Injection on weight gain or loss is not known.
If you have a history of depression then it may increase the risk of developing depression again. Lorazen Injection should not be used alone in depressed patients because it may cause suicidal tendencies in such patients.
Though it is rare, but use of Lorazen Injection can cause memory impairment, which may be more apparent in old age patients.
Taking more than the recommended dose of Lorazen Injection may cause loss of muscle control, low blood pressure, mental confusion, slow breathing and even coma. If you have taken higher than the recommended dose of Lorazen Injection, seek immediate medical help immediately.
No, Lorazen Injection is not an opioid. It belongs to the benzodiazepine group of medicines and is used for short-term treatment (2-4 weeks) only. It is a habit-forming medicine and can make a person physically and psychologically dependent.
Lorazen Injection is used for sleeping difficulties caused due to short-term anxiety. One of the very common side effects of Lorazen Injection is drowsiness and sleepiness. It calms the mind, and therefore, helps a person to sleep.
Lorazen Injection may take around 3 days to get completely removed from the system.
The most important symptom of addiction is that you may feel unpleasant if you do not take Lorazen Injection. Another symptom could be that you may increase the dose on your own to feel its effect.
You should reduce the dose of Lorazen Injection gradually before completely stopping it. Suddenly stopping it may lead to withdrawal symptoms which include loss of the sense of reality, feeling detached from life, and unable to feel emotion. Some patients have also experienced numbness or tingling in the arms or legs, tinnitus (ringing sounds in the ears), uncontrolled or overactive movements, twitching, shaking, feeling sick, being sick, stomach upsets or stomach pain, loss of appetite, agitation and abnormally fast heart beats. It can also cause panic attacks, dizziness or feeling faint, memory loss, hallucinations, feeling stiff and unable to move easily, feeling very warm, convulsions (sudden uncontrolled shaking or jerking of the body) and oversensitivity to light, sound and touch.
The effect of Lorazen Injection on weight gain or loss is not known.
If you have a history of depression then it may increase the risk of developing depression again. Lorazen Injection should not be used alone in depressed patients because it may cause suicidal tendencies in such patients.
Though it is rare, but use of Lorazen Injection can cause memory impairment, which may be more apparent in old age patients.
Taking more than the recommended dose of Lorazen Injection may cause loss of muscle control, low blood pressure, mental confusion, slow breathing and even coma. If you have taken higher than the recommended dose of Lorazen Injection, seek immediate medical help immediately.

Fact Box

Chemical Class

Benzodiazepines Derivative

Habit Forming

Yes

Therapeutic Class

NEURO CNS

Action Class

Benzodiazepines

References

  1. Stahl SM, editor. Lorazepam. In: Stahl's Essential Pschopharmacology: Prescriber's Guide. 5th ed. New York, New York: Cambridge University Press; 2014. pp. 367-71.
  2. Briggs GG, Freeman RK, editors. A Reference Guide to Fetal and Neonatal Risk: Drugs in Pregnancy and Lactation. 10th ed. Philadelphia, PA: Wolters Kluwer Health; 2015. pp. 819-20.
  3. Drugs.com. Lorazepam Pregnancy and Breastfeeding Warnings. [Accessed 25 Mar. 2019] (online) Available from:
  4. Chaves RG, Lamounier JA. Breastfeeding and maternal medications. J Pediatr (Rio J). 2004;80(5 Suppl):S189-S198. [Accessed 20 Mar. 2019] (online) Available from:
  5. Central Drugs Standard Control Organisation (CDSCO). [Accessed 25 Mar. 2019] (online) Available from:
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I feel short term memory loss , anxiety and mood disorder

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Do Mri brain and thyroid testing

i am suffering from anxiety disorder and i am on anxiety medications does ayurveda has any treatment for anxiety disorder

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Yes, Panchkarma is the best you should take sitting of sirodhara
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Tata 1mg's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover everything about particular health conditions, lab tests, medicines, all possible side effects, drug interactions, warnings, alerts, etc. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.

Marketer details

Name: Zenith Healthcare Ltd
Address: 504, Iscon Elegance, Nr. shapath 5, S.G. Road, Ahmedabad-380015.

Vendor Details

Country of origin: India

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Most medicines cannot be sold without a valid prescription, as per the Drugs and Cosmetics Act, 1940 and Rules, 1945
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