Macugen 0.3mg Infusion

Written By Dr. Betina Chandolia, MDS, BDS

Reviewed By Dr. Varun Gupta, MD Pharmacology, MBBS

Last updated on 09 Nov 2024 | 01:10 AM (IST)

Macugen 0.3mg Infusion is used in the treatment of eye condition called wet age-related macular degeneration. It reduces the abnormal growth of blood vessels in the eye. This decreases the chances of swelling as well as fluid and blood leakage that can cause vision loss.

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₹43234 MRP ₹44571.423% off

General Information

Contains

Pegaptanib (0.3mg)

Marketer

Pfizer Ltd

Storage

Store below 30°C

The content is shown in English

Product introduction

Macugen 0.3mg Infusion is administered directly into the eyeball by an eye specialist. You should not self administer this medicine at home. The common side effects include eye pain, redness, blurred or decreased vision and eye discharge.

However, if you experience these side effects for a longer duration or any other symptoms which you think may be due to this medicine, please inform your doctor. It is not advised to drive after administration of this injection as you may feel sleepy or dizzy and your alertness may be reduced.

Uses of Macugen Infusion

Wet age-related macular degeneration

Side effects of Macugen Infusion

Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them

Common side effects of Macugen

Punctate keratitis
High blood pressure
Conjunctival hemorrhage
Cataract
Increased intraocular pressure
Eye pain
Corneal edema
Blurred vision
Eye discomfort
Eyelid inflammation
Diarrhea
Nausea
Anterior chamber inflammation
Eye discharge
Eye irritation
Reduced visual acuity
Visual disturbance
Vitreous floaters
Vitreous opacities
Vitreous haemorrhage
Conjunctivitis
Photopsia (presence of perceived flashes of light)
Bronchitis (inflammation of the airways)
Dizziness
Headache
Urinary tract infection
Corneal epithelial disorders
Joint inflammation
Diabetes
Chest pain
Contact dermatitis
Carotid artery disease

How to use Macugen Infusion

Your doctor or nurse will give you this medicine. Kindly do not self-administer.

How Macugen Infusion works

Macugen 0.3mg Infusion is a monoclonal antibody. It works in cancer by stopping the formation of blood vessels that bring oxygen and nutrients to cancerous cells. This may slow the growth and spread of cancer.

Quick tips

Macugen 0.3mg Infusion is used for the treatment of an eye condition called wet age-related macular degeneration.
It is administered directly into the eyeball by an eye specialist.
It may cause temporary visual disturbances. Don't drive or do anything that requires mental focus until you know how Macugen 0.3mg Infusion affects you.
Inform your doctor if you experience increased eye pain and redness, blurred or decreased vision, or increased sensitivity to light.

Safety advice

Alcohol

CONSULT YOUR DOCTOR

It is not known whether it is safe to consume alcohol with Macugen 0.3mg Infusion. Please consult your doctor.

Pregnancy

SAFE IF PRESCRIBED

Macugen 0.3mg Infusion is generally considered safe to use during pregnancy. Animal studies have shown low or no adverse effects to the developing baby; however, there are limited human studies.

Breast feeding

SAFE IF PRESCRIBED

Macugen 0.3mg Infusion is probably safe to use during breastfeeding. Limited human data suggests that the drug does not represent any significant risk to the baby.

Driving

UNSAFE

Macugen 0.3mg Infusion may decrease alertness, affect your vision or make you feel sleepy and dizzy. Do not drive if these symptoms occur.

Kidney

CONSULT YOUR DOCTOR

There is limited information available on the use of Macugen 0.3mg Infusion in patients with kidney disease. Please consult your doctor.

Liver

CONSULT YOUR DOCTOR

There is limited information available on the use of Macugen 0.3mg Infusion in patients with liver disease. Please consult your doctor.

Frequently asked questions

What is Macugen 0.3mg Infusion sodium?

Macugen 0.3mg Infusion injection belongs to a class of medications called vascular endothelial growth factor (VEGF) antagonists. Macugen 0.3mg Infusion is mainly used for the treatment of exudative (wet) neovascular age-related macular degeneration (AMD, a disease of the eye that affects vision).

Fact Box

Chemical Class

Oligonucleotides

Habit Forming

Therapeutic Class

OPHTHAL

Action Class

Vascular endothelial growth factor (VEGF) inhibitor for AMD

References

Henderer JD, Rapuano CJ. Ocular Pharmacology. In: Brunton LL, Chabner BA, Knollmann BC, editors. Goodman & Gilman’s: The Pharmacological Basis of Therapeutics. New York, New York: McGraw-Hill Medical; 2011. p. 1794.
Briggs GG, Freeman RK, editors. A Reference Guide to Fetal and Neonatal Risk: Drugs in Pregnancy and Lactation. 10th ed. Philadelphia, PA: Wolters Kluwer Health; 2015. p. 1073.
Lake DF, Briggs AD, Akporiaye ET. Immunopharmacology. In: Katzung BG, Masters SB, Trevor AJ, editors. Basic and Clinical Pharmacology. 11th ed. New Delhi, India: Tata McGraw Hill Education Private Limited; 2009. p. 977.
Medscape. Pegaptanib. [Accessed 04 Apr. 2019] (online) Available from:
Pegaptanib sodium. San Dimas, Calirfornia: Gilead Sciences, Inc.; 2004 [revised Jul. 2011]. [Accessed 23 Jan. 2019] (online) Available from:
Drugs.com. Pegaptanib. [Accessed 04 Apr. 2019] (online) Available from:

Patient concerns

Sir, is surgery necessary in the initial stages of macular degeneration or it can be cured with medicines

Dr. Richa Jain

Ophthalmology

What kind of surgery. Macular degeneration can't be cured.Share pic of your prescription

Macular degeneration in left eye

Dr. Richa Jain

Ophthalmology

Get Oct done. n visit

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Tata 1mg's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover everything about particular health conditions, lab tests, medicines, all possible side effects, drug interactions, warnings, alerts, etc. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.

Marketer details

Name: Pfizer Ltd
Address: The Capital, 1802, 18th Floor , Plot No. C-70, ‘G’ Block , Bandra Kurla Complex, Bandra East , Mumbai – 400051.

Vendor Details

Country of origin: India

Lab tests offered by us

Why we need a prescription?

Provide right medicines

Prescriptions are complex documents. We proof read and recheck at various steps to provide you the right medication in the correct form and dose

In accordance with the law

Most medicines cannot be sold without a valid prescription, as per the Drugs and Cosmetics Act, 1940 and Rules, 1945

Macugen 0.3mg Infusion

General Information

Contains

Marketer

Storage

Product introduction

Uses of Macugen Infusion

Side effects of Macugen Infusion

How to use Macugen Infusion

How Macugen Infusion works

Quick tips

Safety advice

Alcohol

Pregnancy

Breast feeding

Driving

Kidney

Liver

Frequently asked questions

What is Macugen 0.3mg Infusion sodium?

Fact Box

Chemical Class

Habit Forming

Therapeutic Class

Action Class

References

Patient concerns

Sir, is surgery necessary in the initial stages of macular degeneration or it can be cured with medicines

Macular degeneration in left eye

Want to know more

Have issue with the content

Disclaimer

Marketer details

Vendor Details

Lab tests offered by us

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