Megapose Plus Tablet
Written By Dr. Swati Mishra, BDS
Reviewed By Dr. Lalit Kanodia, MBA, MD Pharmacology
Last updated on 12 Nov 2024 | 01:00 AM (IST)
Megapose Plus Tablet is a combination of two medicines used in the treatment of schizophrenia, a mental disorder that can result in hallucinations or delusions. It alters the thoughts and elevates the mood, improving the person’s ability to think, feel and behave.
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General Information
Contains
Flupenthixol (0.5mg)+ Escitalopram Oxalate (10mg)
Marketer
Mankind Pharma Ltd
Storage
Store below 30°C
The content is shown in English


Product introduction
Megapose Plus Tablet may be taken with or without food, preferably at the same time each day. Take it at the same time each day as this helps to maintain a consistent level of medicine in the body. Take this medicine in the dose and duration as advised by your doctor and if you have missed a dose, take it as soon as you remember it. Do not skip any doses and finish the full course of treatment even if you feel better. It is important that this medication is not stopped suddenly without talking to your doctor as it may worsen your symptoms.
Some common side effects of this medicine include dry mouth, vomiting, stomach upset, delayed ejaculation, sedation, urinary retention, low sexual desire, muscle rigidity, restlessness and tremors. Initially, this medicine may cause a sudden drop in blood pressure when you change positions, rise slowly if you have been sitting or lying down. However, these are temporary and usually resolve on their own. Please consult your doctor if these do not subside or bother you. It may also cause dizziness and sleepiness, do not drive or do anything that requires mental focus until you know how this medicine affects you.
Inform your doctor if you experience any abnormal movements, particularly of the face, lips, jaw, and tongue while taking this medicine. Your doctor may advise for regular monitoring of blood sugar and cholesterol levels. Additionally, avoid drinking alcohol while taking this medicine as it can make drowsiness worse. This medicine can also lead to weight gain, eat a healthy balanced diet, avoid snacking with high-calorie food, and exercise regularly.
Some common side effects of this medicine include dry mouth, vomiting, stomach upset, delayed ejaculation, sedation, urinary retention, low sexual desire, muscle rigidity, restlessness and tremors. Initially, this medicine may cause a sudden drop in blood pressure when you change positions, rise slowly if you have been sitting or lying down. However, these are temporary and usually resolve on their own. Please consult your doctor if these do not subside or bother you. It may also cause dizziness and sleepiness, do not drive or do anything that requires mental focus until you know how this medicine affects you.
Inform your doctor if you experience any abnormal movements, particularly of the face, lips, jaw, and tongue while taking this medicine. Your doctor may advise for regular monitoring of blood sugar and cholesterol levels. Additionally, avoid drinking alcohol while taking this medicine as it can make drowsiness worse. This medicine can also lead to weight gain, eat a healthy balanced diet, avoid snacking with high-calorie food, and exercise regularly.
Uses of Megapose Plus Tablet
Benefits of Megapose Plus Tablet
Schizophrenia
Schizophrenia is a mental disorder in which a person’s thinking ability, feelings and behavior become abnormal. Megapose Plus Tablet helps restore the chemical imbalances in the brain that are responsible for such changes. It improves thoughts, behavior and enhances the quality of life.
Schizophrenia is a mental disorder in which a person’s thinking ability, feelings and behavior become abnormal. Megapose Plus Tablet helps restore the chemical imbalances in the brain that are responsible for such changes. It improves thoughts, behavior and enhances the quality of life.
Side effects of Megapose Plus Tablet
Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them
Common side effects of Megapose Plus
- Dryness in mouth
- Vomiting
- Upset stomach
- Delayed ejaculation
- Sedation
- Weight gain
- Orthostatic hypotension (sudden lowering of blood pressure on standing)
- Urinary retention
- Dizziness
- Increased prolactin level in blood
- Anorgasmia (decreased orgasm)
- Low sexual desire
- Muscle stiffness
- Restlessness
- Tremors
How to use Megapose Plus Tablet
Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Megapose Plus Tablet may be taken with or without food, but it is better to take it at a fixed time.
How Megapose Plus Tablet works
Megapose Plus Tablet is a combination of two medicines: Flupenthixol and Escitalopram Oxalate which have anxiety-lowering and mood-elevating effects. Flupenthixol is a typical antipsychotic. It works by blocking the action of dopamine, a chemical messenger in the brain that affects thoughts and mood. Escitalopram Oxalate is selective serotonin reuptake inhibitor (SSRI) which increases the levels of serotonin, a chemical messenger that improves mood.
Quick tips
- Megapose Plus Tablet is used for the treatment of schizophrenia.
- It is better to take it at night as this medicine may produce drowsiness or sleepiness.
- Try to keep your regular appointments with your doctor. This is so your doctor can check on your progress.
- Before taking this medicine, tell your doctor if you have experienced fits (convulsions) either recently or in the past.
- Inform your doctor if you have severe heart, liver, Parkinsons' disease, or diabetes before starting your treatment.
- Avoid exposure to sunlight or tanning beds. Megapose Plus Tablet can make you sunburn more easily. Wear protective clothing and use sunscreen (SPF 30 or higher) when you are outdoors.
Safety advice

Alcohol
UNSAFE
It is unsafe to consume alcohol with Megapose Plus Tablet.

Pregnancy
CONSULT YOUR DOCTOR
Megapose Plus Tablet may be unsafe to use during pregnancy. Although there are limited studies in humans, animal studies have shown harmful effects on the developing baby. Your doctor will weigh the benefits and any potential risks before prescribing it to you. Please consult your doctor.

Breast feeding
CONSULT YOUR DOCTOR
Megapose Plus Tablet is probably unsafe to use during breastfeeding. Limited human data suggests that the drug may pass into the breastmilk and harm the baby.

Driving
UNSAFE
Megapose Plus Tablet may cause side effects which could affect your ability to drive.

Kidney
CAUTION
Megapose Plus Tablet should be used with caution in patients with severe kidney disease. Dose adjustment of Megapose Plus Tablet may be needed. Please consult your doctor.

Liver
CAUTION
Megapose Plus Tablet should be used with caution in patients with liver disease. Dose adjustment of Megapose Plus Tablet may be needed. Please consult your doctor.
Fact Box
Habit Forming
No
Therapeutic Class
NEURO CNS
References
- Flupenthixol. Everard Close, Abbey View St Albans: Lundbeck Limited; 1982 [revised Dec. 2016]. [Accessed 23 Apr. 2019] (online) Available from:
- Escitalopram. Copenhagen, Denmark: H Lundbeck A/S; 2016. [Accessed 23 Apr. 2019] (online) Available from:
- Flupenthixol. Denmark: Lundbeck; 2013. [Accessed 23 Apr. 2019] (online) Available from:
- Drugs.com. Escitalopram Oxalate. [Accessed 23 Apr. 2019] (online) Available from:
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User feedback
Once A Day
94%
Twice A Day
6%
Anxiety disorder
56%
Depression
22%
Others
11%
Post traumatic stress disorder
11%
Excellent
50%
Poor
33%
Average
17%
Insomnia (difficulty in sleeping)
50%
Sleepiness
50%
Patient concerns
Dear Sir I m mental patient and I was taken megapose plus tablet but now gov. Banned this. So I want substitute tablet
Dr. Venkatraju Kalidindi
Psychiatry
Dear 1mg user, medicines gives quick relief and has side effects too so consult your doctor and see how to reduce dose and control totally, later you can take counselling that really helps you. Pay Rs 99 and call me on my phone www.dontfeel.com for counselling
Suffering Schizophrnia from last 20+ years. Is cure able ?
Dr. Ambrish Dharmadhikari
Psychiatry
We are here to helpSchizophrenia is chronic disorderSymptoms can be stopped from expressingCure is difficult word to say in schizophrenia
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Tata 1mg's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover everything about particular health conditions, lab tests, medicines, all possible side effects, drug interactions, warnings, alerts, etc. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.
Marketer details
Name: Mankind Pharma Ltd
Address: 208, Okhla Industrial Estate, Phase III, New Delhi - 110020
Address: 208, Okhla Industrial Estate, Phase III, New Delhi - 110020
Vendor Details
Country of origin: India
Lab tests offered by us
- CBC (Complete Blood Count)
- FBS (Fasting Blood Sugar)
- Thyroid Profile Total (T3, T4 & TSH)
- HbA1c (Glycosylated Hemoglobin)
- Glucose - Postprandial
- Lipid Profile
- Vitamin D (25-Hydroxy)
- Urine R/M (Urine Routine & Microscopy)
- Coronavirus Covid-19 Test (RT-PCR technique)
- LFT (Liver Function Test)
- Kidney Function Test
- TSH (Thyroid Stimulating Hormone) Ultrasensitive
- ESR (Erythrocyte Sedimentation Rate)
- Uric Acid
- Vitamin B12
- C- Reactive Protein Quantitative
- Urine Culture and Sensitivity
- Serum Electrolyte
- Serum Calcium
- Creatinine
- Diabetes Screening
- KFT with Electrolytes (Kidney Function Test with Electrolytes)
- Cholesterol - Total
- Hemoglobin
- Complete Haemogram
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