Megarest 5mg Injection

Reviewed By Dr. Varun Gupta, MD Pharmacology, MBBS

Last updated on 12 Nov 2024 | 01:09 AM (IST)

Megarest 5mg Injection is used as a sedative or for conscious sedation before diagnostic or therapeutic procedures. It relieves anxiety and muscle tensions, thus making the person comfortable before investigations or minor surgical or dental procedures.

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₹34.9 MRP ₹363% off

General Information

Contains

Midazolam (5mg)

Marketer

Vhb Life Sciences Inc

Storage

Store below 30°C

The content is shown in English

Product introduction

Megarest 5mg Injection can be used for sedation in intensive care units and to obtain anesthesia in elderly people before undergoing any surgical procedure. This medicine is given as an injection under the supervision of a healthcare professional in a hospital setting. It may be administered by intravenous injection (injection into a vein) or by intravenous infusion (given by a drip into a vein).

The most common side effects of this medicine include hiccup, nausea, vomiting, cough, sedation, headache, drowsiness, and injection site reactions (pain, swelling, and redness). You should not drive or do anything that requires mental focus until you know how this medicine affects you. Inform your doctor if you are pregnant, planning to conceive, or breastfeeding before taking this medicine.

Uses of Megarest Injection

Conscious sedation during diagnostic or therapeutic procedures

Benefits of Megarest Injection

Conscious sedation during diagnostic or therapeutic procedures
Megarest 5mg Injection is an anesthetic agent. It is used before medical procedures and surgery to cause drowsiness, relieve anxiety, and prevent any memory of the event. It is also sometimes given as part of the anesthesia during surgery to produce a loss of consciousness.This helps to carry out surgical procedures or diagnostic procedures without causing pain or discomfort to the patient. It is given as an injection by a specialist doctor called anesthetist in a hospital setup.

Side effects of Megarest Injection

Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them

Common side effects of Megarest

Hiccup
Nausea
Cough
Headache
Drowsiness
Sedation
Vomiting
Injection site reactions (pain, swelling, redness)

How to use Megarest Injection

Your doctor or nurse will give you this medicine. Kindly do not self administer.

How Megarest Injection works

Megarest 5mg Injection is a benzodiazepine. It works by increasing the action of a chemical messenger (GABA) which suppresses the abnormal and excessive activity of the nerve cells in the brain.

Quick tips

The addiction / habit-forming potential of this medicine is very high. Take it only as per the dose and duration advised by your doctor
It may cause dizziness. Do not drive or do anything that requires mental focus until you know how this medicine affects you.
Avoid consuming alcohol as it may increase dizziness and drowsiness.
Inform your doctor if you are pregnant, planning to conceive or breastfeeding.
Do not stop taking medication suddenly without talking to your doctor as that may lead to nausea, anxiety, agitation, flu-like symptoms, sweating, tremor, and confusion.

Safety advice

Alcohol

UNSAFE

Megarest 5mg Injection may cause excessive drowsiness with alcohol.

Pregnancy

CONSULT YOUR DOCTOR

Megarest 5mg Injection is unsafe to use during pregnancy as there is definite evidence of risk to the developing baby. However, the doctor may rarely prescribe it in some life-threatening situations if the benefits are more than the potential risks. Please consult your doctor.

Breast feeding

SAFE IF PRESCRIBED

Megarest 5mg Injection is probably safe to use during breastfeeding. Limited human data suggests that the drug does not represent any significant risk to the baby.
Megarest 5mg Injection should be used for short periods and sleepiness of the baby should be watched. The withdrawal of Megarest 5mg Injection should be gradual.

Driving

UNSAFE

Megarest 5mg Injection may cause side effects which could affect your ability to drive.
Megarest 5mg Injection may make the patient sleepy, forgetful or affect their concentration or coordination. This may affect their ability to drive.

Kidney

CAUTION

Megarest 5mg Injection should be used with caution in patients with severe kidney disease. Dose adjustment of Megarest 5mg Injection may be needed. Please consult your doctor.

Liver

CONSULT YOUR DOCTOR

There is limited information available on the use of Megarest 5mg Injection in patients with liver disease. Please consult your doctor.

Frequently asked questions

Is Megarest 5mg Injection safe?

Megarest 5mg Injection is safe if used at prescribed doses for the prescribed duration as advised by your doctor

Is Megarest 5mg Injection a controlled substance?

Yes, Megarest 5mg Injection is a controlled substance

Is Megarest 5mg Injection a sedative?

Yes, Megarest 5mg Injection a sedative medication used before and during diagnostic or surgical procedures either in combination with or without local anesthesia

Is Megarest 5mg Injection a benzodiazepine?

Yes, Megarest 5mg Injection belongs to benzodiazepine class of sedative medication

Does Megarest 5mg Injection have analgesic properties?

No, Megarest 5mg Injection does not have any analgesic properties. It is used as a central nervous system depressant that slows brain activity, causes relaxation and induces sleep (anesthetic)

Does Megarest 5mg Injection cause retrograde amnesia?

Yes, Megarest 5mg Injection causes retrograde amnesia (short term loss of memory)

Fact Box

Chemical Class

Benzodiazepines Derivative

Habit Forming

Yes

Therapeutic Class

NEURO CNS

Action Class

Benzodiazepines

References

Stahl SM, editor. Midazolam. In: Stahl's Essential Pschopharmacology: Prescriber's Guide. 5th ed. New York, New York: Cambridge University Press; 2014. pp. 431-33.
Briggs GG, Freeman RK, editors. A Reference Guide to Fetal and Neonatal Risk: Drugs in Pregnancy and Lactation. 10th ed. Philadelphia, PA: Wolters Kluwer Health; 2015. pp. 914-15.
Drugs.com. Midazolam Pregnancy and Breastfeeding Warnings. [Accessed 25 Mar 2019] (online) Available from:
Chaves RG, Lamounier JA. Breastfeeding and maternal medications. J Pediatr (Rio J). 2004;80(5 Suppl):S189-S198. [Accessed 20 Mar. 2019] (online) Available from:
Central Drugs Standard Control Organisation (CDSCO). [Accessed 25 Mar. 2019] (online) Available from:

Patient concerns

My patient lives in qatar He has allergy problem due to hot and cold Is loratadine works good Pls suggest best allergic medine that can cure permanent

Dr. Gladson Guddappa Uchil

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He needs to consult an Allergist who will do Diagnostic Skin Prick & Patch tests to identify the offending allergen. This is to be followed by Allergy Counselling and Therapeutic Immunotherapy

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Dr. Pushkar Mani

Physician

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Tata 1mg's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover everything about particular health conditions, lab tests, medicines, all possible side effects, drug interactions, warnings, alerts, etc. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.

Marketer details

Name: Vhb Life Sciences Inc
Address: 50-AB, Government Industrial Estate, Charkop Naka, Kandivali West , Mumbai - 400067, Maharashtra, India

Vendor Details

Country of origin: India

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