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Memantal 10mg Tablet

Written By Dr. Swati Mishra, BDS
Reviewed By Dr. Khushbu Goel, DM, MD
Last updated on 11 Nov 2024 | 01:02 AM (IST)
Memantal 10mg Tablet is a medicine used in the treatment of Alzheimer's disease. It helps to slow down the progression of moderate to severe Alzheimer's disease by improving memory and thinking. This medicine works by blocking a chemical messenger involved in the transmission of nerve signals.
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General Information

Contains

Memantine (10mg)

Marketer

East West Pharma

Storage

Store below 30°C
The content is shown in English
Memantal 10mg Tablet image

Product introduction

Memantal 10mg Tablet maybe taken with or without food. However, it is advised to take it at the same time each day to maintain a consistent level of medicine in the blood. If you missed a dose, take it as soon as you remember. Do not skip any doses and finish the full course of treatment even if you feel better. It is important that this medication is not stopped suddenly without talking to your doctor.

The most common side effects of this medicine are dizziness, headache, confusion, and constipation. It may also cause dizziness and sleepiness, so do not drive or do anything that requires mental focus until you know how this medicine affects you.

Before taking this medicine, inform the doctor if you have a history of seizures, kidney disease, heart disease, or liver disease. Let your doctor also know if you are taking any other medicines for any medical conditions. Pregnant and breastfeeding women should consult their doctors before taking this medicine.

Uses of Memantal Tablet

Benefits of Memantal Tablet

Alzheimer's disease
Memantal 10mg Tablet improves learning, memory and information processing (cognitive function) in people with moderate to severe Alzheimer's disease. These problems in memory and thinking may start interfering with daily activities and worsen your condition. This medicine will help in managing Alzheimer’s disease effectively. It will make it easier for you to carry out your daily activities and improve your quality of life. Do not stop taking it unless advised by the doctor. It can take several weeks for your symptoms to improve; so keep using the medicine even if you do not think it is working.

Side effects of Memantal Tablet

Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them
Common side effects of Memantal
  • Dizziness
  • Headache
  • Confusion
  • Constipation

How to use Memantal Tablet

Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Memantal 10mg Tablet may be taken with or without food, but it is better to take it at a fixed time.

How Memantal Tablet works

Memantal 10mg Tablet is an N-methyl-D-aspartate (NMDA) receptor antagonist. Memory loss in Alzheimer’s disease is due to excessive production of glutamate (chemical messenger) in the brain which is mediated by NMDA receptors. Memantal 10mg Tablet works by preventing the action of NMDA receptors and regulates the production of glutamate.  involved in the transmission of nerve signals. This is how it prevents memory loss in Alzheimer’s disease.

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Quick tips

  • You have been prescribed Memantal 10mg Tablet to treat dementia (memory loss) in patients with Alzheimer's disease.
  • It is well tolerated and has lesser side effects as compared to other similar medicines.
  • Be cautious while driving or doing anything that requires concentration until you know how Memantal 10mg Tablet affects you.
  • Inform your doctor if you have a history of seizures, kidney disease, heart disease, or liver disease.
  • Inform your doctor if you are pregnant, planning to conceive, or breastfeeding.

Safety advice

Alcohol

Alcohol

CAUTION
Caution is advised when consuming alcohol with Memantal 10mg Tablet. Please consult your doctor.
Pregnancy

Pregnancy

SAFE IF PRESCRIBED
Memantal 10mg Tablet is generally considered safe to use during pregnancy. Animal studies have shown low or no adverse effects to the developing baby; however, there are limited human studies.
Breast feeding

Breast feeding

CONSULT YOUR DOCTOR
Information regarding the use of Memantal 10mg Tablet during breastfeeding is not available. Please consult your doctor.
Driving

Driving

UNSAFE
Memantal 10mg Tablet may cause side effects which could affect your ability to drive.
Kidney

Kidney

CAUTION
Memantal 10mg Tablet should be used with caution in patients with severe kidney disease. Dose adjustment of Memantal 10mg Tablet may be needed. Please consult your doctor.
Liver

Liver

CAUTION
Memantal 10mg Tablet should be used with caution in patients with severe liver disease. Dose adjustment of Memantal 10mg Tablet may be needed. Please consult your doctor.
Limited information is available on the use of Memantal 10mg Tablet in these patients. No dose adjustment is recommended in patients with mild to moderate liver disease.

Frequently asked questions

No, Memantal 10mg Tablet does not have abuse potential. On the contrary, it may prevent excess use of addictive drugs such as morphine or ethanol.
Memantal 10mg Tablet should be taken orally once a day. To benefit from your medicine you should take it regularly every day at the same time of the day. The tablets should be swallowed with some water. The tablets can be taken with or without food.
For Memantal 10mg Tablet to start working and show its full benefits, it may require between 3 and 8 hours. The doctor may require a follow-up clinical assessment to check the progress after 4 weeks and then 6 months after the first assessment.
The symptoms which can be observed due to an overdose of Memantal 10mg Tablet include tiredness, weakness, drowsiness, confusion, hallucinations, and/or vomiting. Some may also experience diarrhea, vertigo, agitation, aggression, and walking difficulty.
Memantal 10mg Tablet belongs to a class of medications called N-methyl-D- aspartate (NMDA) receptor antagonists. It works by decreasing abnormal activity in the brain. Memantal 10mg Tablet may improve the ability to think and remember. It may also reduce the deterioration of these abilities in people who have Alzheimer's disease. However, with time the effectiveness of this medicine will reduce and it may not be able to cure Alzheimer's disease or prevent the loss of these abilities.
Dementia is a syndrome in which there is deterioration in memory, thinking, behavior, and the ability to perform everyday activities. Dementia is one of the major causes of disability and dependency among older people worldwide. Alzheimer disease is the most common form of dementia which contributes to around 60 to 70% of cases.
No, Memantal 10mg Tablet should not be stopped even if you feel well. This medicine only helps to control the symptoms of Alzheimer's disease but does not cure it. If you need to stop the medication then doctor should be consulted first.
Yes, Memantal 10mg Tablet may make you sleepy. Memantal 10mg Tablet has minor to moderate influence on the ability to drive and usage of machines. In such cases, outpatients should be warned to take special care.
Yes, Memantal 10mg Tablet can be combined with donepezil, as there will be no increased adverse effects. However, this combination will not cure Alzheimer's, but it can only improve thinking ability, short term memory, and other related symptoms.
Memantal 10mg Tablet can interact with several medicines. Taking other medicines along with Memantal 10mg Tablet can either make Memantal 10mg Tablet less effective or increase its side effect. Do not take any medicine without talking to your doctor.
Yes, Memantal 10mg Tablet may interfere with the working of hydrochlorothiazide (HCT). It decreases the levels of HCT which will reduce the effectiveness of HCT. Also, procainamide and quinidine may increase levels of Memantal 10mg Tablet which may cause increased toxicity.
No, keep using Memantal 10mg Tablet as advised by your doctor, even if you feel well. Stopping Memantal 10mg Tablet can bring back your symptoms of dementia.

Fact Box

Chemical Class

Amantadine Derivative

Habit Forming

No

Therapeutic Class

NEURO CNS

Action Class

NMDA inhibitors- Alzheimer's disease

References

  1. Katzung BG. Special Aspect of Geriatric Pharmacology. In: Katzung BG, Masters SB, Trevor AJ, editors. Basic and Clinical Pharmacology. 11th ed. New Delhi, India: Tata McGraw Hill Education Private Limited; 2009. pp. 1141-42.
  2. Standaert DG, Roberson ED. Treatment of Central Nervous System Degenerative Disorders. In: Brunton LL, Chabner BA, Knollmann BC, editors. Goodman & Gilman’s: The Pharmacological Basis of Therapeutics. 12th ed. New York, New York: McGraw-Hill Medical; 2011. p. 622.
  3. Stahl SM, editor. Memantine. In: Stahl's Essential Pschopharmacology: Prescriber's Guide. 5th ed. New York, New York: Cambridge University Press; 2014. pp. 397-400.
  4. Memantine HCl. Dublin, Ireland: Forest Laboratories Ireland Ltd.; 2003 [revised Oct 2013]. [Accessed 25 Jan. 2019] (online) Available from:
  5. Memantine hydrochloride [EMC SmPC]. Hatfield, Hertfordshire: Generics UK T/A Mylan; 2013 [revised Jun. 2015]. [Accessed 25 Mar 2019] (online) Available from:
  6. Central Drugs Standard Control Organisation (CDSCO). [Accessed 25 Mar. 2019] (online) Available from:
  7. Central Drugs Standard Control Organisation. Memantine. [Accessed 11 Jul. 2023]. (online) Available from:
  8. Memantine Hydrochloride [Patient Information Leaflet]. Bachupally, India: Dr. Reddy’s Laboratories Limited. [Accessed 11 Jul. 2023]. (online) Available from:
  9. Memantine hydrochloride [Prescribing Information]. Panchmahal, Gujarat: Alembic Pharmaceuticals Limited (Formulation Division); 2023. [Accessed 11 Jul. 2023]. (online) Available from:
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Patient concerns

Sir, My father ( an advocate) has developed symptoms of Alzheimer recently and sometimes he takes medicines on his own. He gets weak and unable to walk after taking tablets. Is there any test which can tell which medicines that he took? He takes Ayurved, Allopath, Homeopathy all and does not listen to me. Kindly help

Dr. Ila Jain Khandelwal
Dr. Ila Jain Khandelwal
Pathology
Dear Sir Thank you for consulting with me. Alzheimer's disease is a difficult disease to handle since patient develops dementia or forgetfulness. There are no blood tests which can tell you which medicines he took. Please consult a neurologist/ Psychiatrist

Why the failure of Alzheimer's therapy now a days???

Dr. Vikas Sharma
Dr. Vikas Sharma
Neurology
as the disese mechanisms are still not defined in absolute terms; still PATIENT is needed and is ongoing
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Tata 1mg's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover everything about particular health conditions, lab tests, medicines, all possible side effects, drug interactions, warnings, alerts, etc. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.

Marketer details

Name: East West Pharma
Address: No. 10, 2nd Cross, Maravaneri, Salem - 636007, Tamil Nadu.

Vendor Details

A licensed vendor partner from your nearest location will deliver Memantal 10mg Tablet. Once the pharmacy accepts your order, the details of the pharmacy will be shared with you. Acceptance of your order is based on the validity of your doctor's ℞ and the availability of this medicine.

In case of any issues, contact us

Email ID: [email protected]
Phone Number: 0124-4166666
Address: 5th Floor Tower - B of the Presidency Building, 46/4 Mehrauli Gurgaon Road, Sector 14, Gurugram, Haryana-122001, India

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