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Metacin 250mg Suppository

Written By Dr. Shreya Gupta, MDS (Oral Pathology & Microbiology), BDS
Reviewed By Dr. Shilpa Garcha, MD (Pharmacology), MBBS
Last updated on 12 Nov 2024 | 01:06 AM (IST)
Metacin 250mg Suppository helps ease pain and bring down high body temperature (fever). It works by blocking certain chemical messengers in the brain that increase the body’s temperature and cause pain. It is usually only given to children who are unable to take oral forms of this medicine.
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General Information

Contains

Paracetamol (250mg)

Marketer

Themis Pharmaceuticals Prop Chemosyn Ltd

Storage

Store below 30°C
The content is shown in English
Metacin 250mg Suppository image

Your child’s medicine at a glance

Metacin 250mg Suppository is for rectal use only and should never be taken by mouth. Encourage your child to empty the bowel before inserting the medicine as that will enhance the absorption of the medicine. Also, ask your child to slow down and avoid moving around a lot at least for an hour after placing the medicine. The dose will depend upon your child’s age, body weight, and severity of the infection, so stick to the dose, duration, and way prescribed by your child’s doctor. If your child passes stool within 30 minutes of inserting Metacin 250mg Suppository, you will have to insert it again.

Do not give your child Metacin 250mg Suppository along with other medicines (many cold and flu medicines and other painkillers) that contain paracetamol, as this may result in overdosing and cause dangerous side effects such as hepatotoxicity (liver damage). Always check the ingredients of any other medicine before giving them to your child in combination with this medicine. Also, do not stop giving the medicine abruptly even if your child starts to feel better. Doing so may bring back the symptoms or worsen the condition.

Generally, this medicine is well-tolerated by the children. However, temporary side effects such as anal irritation, nausea, vomiting, and constipation may occur in some children. Consult your doctor in case these episodes become bothersome for your child.

This medicine is often considered safe and effective but may not be suitable for everybody. Inform your doctor if your child is undergoing treatment for any blood-related disorder, is allergic to any medicinal compound, or has any birth defects, liver impairment, or kidney dysfunction. This will help your child’s doctor evaluate the dose and suitability of this medicine in a better way.

Uses of Metacin 250mg Suppository in children

Benefits of Metacin 250mg Suppository for your child

Pain relief
Metacin 250mg Suppository is a common painkiller used to treat aches and pains. It works by blocking chemical messengers in the brain that tell us we have pain. It is effective in relieving pain caused by headache, migraine, nerve pain, toothache, sore throat, period (menstrual) pains, arthritis, and muscle aches. This medicine is very widely used and very rarely causes side effects if taken at the right dosage. Take it as it is prescribed to get the most benefit. Do not take more or for longer than needed as that can be dangerous. In general, you should take the lowest dose that works, for the shortest possible time. It is also the first choice of painkiller during pregnancy or breastfeeding.
Treatment of Fever
Metacin 250mg Suppository is also used to reduce a high temperature (fever). It works by blocking the release of certain chemical messengers that cause fever. It may be prescribed alone or in combination with another medicine. You should take it regularly as advised by your doctor.

Side effects of Metacin 250mg Suppository in children

Metacin 250mg Suppository does not pose serious side effects and is well-tolerated by children. In case the side effects do occur, they’re likely to subside once the body adapts to the medicine. Consult your child’s doctor if these side effects persist or bother your child. The most common side effects include-
Common side effects of Metacin
  • Stomach pain
  • Vomiting
  • Anal irritation
  • Nausea
  • Constipation

How can I give Metacin 250mg Suppository to my child?

Remove the wrapper from the suppository before inserting it. Keep lying down for about 15 minutes after insertion so that the suppository does not come out before it melts.

How Metacin Suppository works

Metacin 250mg Suppository possesses analgesic (pain-reliever) and antipyretic (lowers body temperature) properties. It is absorbed rapidly into the bloodstream from the rich blood supply of the rectal area. Once absorbed, it provides relief by blocking certain chemical messengers and pathways in the brain that send signals about pain and fever.

All substitutes for Metacin 250mg Suppository

For information purposes only. Consult a doctor before taking any medicine.

Suppol 250mg Suppository

by Meridian Enterprises Pvt Ltd
₹16.3/suppository
40% costlier
<h3 class=bodySemiBold>Suppol 250mg Suppository</h3>

Suppol 250mg Suppository

by Meridian Enterprises Pvt Ltd
₹20/suppository
72% costlier
<h3 class=bodySemiBold>Suppol 250mg Suppository</h3>

Rectol 250 Suppository

by Bliss Gvs Pharma Limited
₹10.08/suppository
13% cheaper
<h3 class=bodySemiBold>Rectol 250 Suppository</h3>

Junimol RDS 250mg Suppository

by Elder Pharmaceuticals Ltd
₹8.56/suppository
26% cheaper
<h3 class=bodySemiBold>Junimol RDS 250mg Suppository</h3>

Quick tips

  • Metacin 250mg Suppository is for use in children who find it difficult to take paracetamol as tablets or syrup.
  • This medicine is for rectal use only and should not be taken by mouth.
  • Never give any other medicine formulation containing paracetamol along with this medicine as that may lead to serious side effects.
  • Inform the doctor if your child has liver disease as the dose may need to be adjusted.
  • If Metacin 250mg Suppository does not seem to be helping your child, contact your doctor for advice. Do not give extra doses.

Safety advice

Kidney

Kidney

CAUTION
Metacin 250mg Suppository should be used with caution in patients with severe kidney disease. Dose adjustment of Metacin 250mg Suppository may be needed. Please consult your doctor.
However, Metacin 250mg Suppository contains paracetamol which is considered the safest painkiller for children with kidney disease.
Liver

Liver

CAUTION
Metacin 250mg Suppository should be used with caution in patients with liver disease. Dose adjustment of Metacin 250mg Suppository may be needed. Please consult your doctor.
However, the use of Metacin 250mg Suppository is not recommended in children with severe liver disease and active liver disease.
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Frequently asked questions

Metacin 250mg Suppository is meant to be placed inside the rectum (bottom area). It uses the body's heat and melts inside, resulting in direct absorption into the bloodstream and rendering quick relief. Use Metacin 250mg Suppository as directed by your child’s doctor. Before insertion, wash your hands properly. Guide your child to lie down sideways or on the belly. Hold one buttock gently to get access to the rectal area. Unwrap the medicine and hold the rounded end close to the rectum. Use one finger to gently push Metacin 250mg Suppository into the rectum. Ask your child to remain still for about 15 minutes as it will prevent the medicine from popping out. Clean your hands again with soap and water to ensure hygiene.
It will depend on the strength of the medicine and the age of your child. Always follow your doctor's instructions regarding how much and how often the medicine should be given to your child. In case you are not sure about how much to give, consult your child’s doctor.
You can give this medicine if your child has a temperature of 38.3°C (101°F) or higher. But, you must always try to speak to your child’s doctor first.
If the fever doesn't come down, the cause might be an infection (virus or bacteria). It is advised to consult your child’s doctor for specific treatment.
Keep this medicine beyond the reach of the children. To prevent melting, keep the medicine in the refrigerator but do not freeze.
It is advised to use Metacin 250mg Suppository with caution if the child has malnutrition, G6PD deficiency, liver disease, or any medicinal allergy. So, do not hesitate to share your child’s complete medical history with the doctor as that will help the doctor decide whether the medicine is safe for your child or not.

Fact Box

Chemical Class

P-Aminophenol Derivative

Habit Forming

No

Therapeutic Class

PAIN ANALGESICS

Action Class

Analgesic & Antipyretic-PCM

Related lab tests

Complete Blood Count

References

  1. Furst DE, Ulrich RW, Varkey-Altamirano C. Nonsteroidal Anti-Inflammatory Drugs, Disease Modifying Antirheumatic Drugs, Nonopioids Analgesics, & Drugs Used in Gout. In: Katzung BG, Masters SB, Trevor AJ, editors. Basic and Clinical Pharmacology. 11th ed. New Delhi, India: Tata McGraw Hill Education Private Limited; 2009. pp. 635-36.
  2. Grosser T, Smyth E, FitzGerald GA. Anti-Inflammatory, Antipyretic, and Analgesic Agents; Pharmacotherapy of Gout. In: Brunton LL, Chabner BA, Knollmann BC, editors. Goodman & Gilman’s: The Pharmacological Basis of Therapeutics. 12th ed. New York, New York: McGraw-Hill Medical; 2011. pp. 982-84.
  3. Grosser T, Smyth E, FitzGerald G. Pharmacotherapy of Inflammation, Fever, Pain, and Gout. In: Brunton LL, Hilal-Dandan R, Knollmann BC (Editors). Goodman & Gilman's: The Pharmacological Basis of Therapeutics. 13th ed. New York, New York: McGraw-Hill Medical; 2018.
  4. Children’s Health Queensland Hospital and Health Service. Emergency care of children: Medication guides for use in Queensland. [Accessed 26 Dec. 2020] (online) Available from:
  5. Royal College of Paediatrics and Child Health. Medicines for Children - information for parents and carers. [Accessed 26 Dec. 2020] (online) Available from:
  6. Paracetamol [EMC Patient Leaflet]. Leeds, UK: Rosemont Pharmaceuticals Limited; 2019. [Accessed 26 Dec. 2020] (online) Available from:
  7. Aabideen K, Moulton LS, Sills J. Accidental staggered paracetamol overdose: An interesting case report. J Pharmacol Pharmacother. 2011;2(3):189-190. [Accessed 26 Dec. 2020] (online) Available from:
  8. MedlinePlus. Acetaminophen. [Accessed 26 Dec. 2020] (online) Available from:
  9. Section on Clinical Pharmacology and Therapeutics; Committee on Drugs, Sullivan JE, Farrar HC. Fever and antipyretic use in children. Pediatrics. 2011;127(3):580-7. [Accessed 26 Dec. 2020] (online) Available from:
  10. Offringa M, Newton R, Cozijnsen MA, et al. Prophylactic drug management for febrile seizures in children. Cochrane Database Syst Rev. 2017;2(2):CD003031. [Accessed 29 Dec. 2020] (online) Available from:
  11. Paracetamol [Package Leaflet]. Norfolk, UK: Amdeepcha Limited; 2022. [Accessed 25 Jul. 2024] (online) Available from:
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Patient concerns

Fever and body pain head pain .

Dr. Sunil Sekhri
Dr. Sunil Sekhri
Diabetology
Tab Metacin 1 tab SOS

Body pain, headache,with fever

Dr. Sunil Sekhri
Dr. Sunil Sekhri
Diabetology
Tab Metacin 500 1 tab SOS and a clinical examination
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Disclaimer

Tata 1mg's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover everything about particular health conditions, lab tests, medicines, all possible side effects, drug interactions, warnings, alerts, etc. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.

Marketer details

Name: Themis Pharmaceuticals Prop Chemosyn Ltd
Address: 69-B , J-type area ,G.I.D.C. Industrial Estate,Near CNG Gas Station,Vapi- 396195

Vendor Details

Country of origin: India
A licensed vendor partner from your nearest location will deliver Metacin 250mg Suppository. Once the pharmacy accepts your order, the details of the pharmacy will be shared with you. Acceptance of your order is based on the validity of your doctor's ℞ and the availability of this medicine.

In case of any issues, contact us

Email ID: [email protected]
Phone Number: 0124-4166666
Address: 5th Floor Tower - B of the Presidency Building, 46/4 Mehrauli Gurgaon Road, Sector 14, Gurugram, Haryana-122001, India

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