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Methermat 0.2mg Injection

Written By Dr. Swati Mishra, BDS
Reviewed By Dr. Khushbu Goel, DM, MD
Last updated on 12 Nov 2024 | 01:10 AM (IST)
Methermat 0.2mg Injection is a prescription medicine used to treat acute migraine headache. This medicine helps by narrowing the blood vessels thereby relieving the migraine headaches.
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1/2
1 ml Injection
 
 
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General Information

Contains

Ergotamine (0.2mg)

Marketer

Makers Laboratories Ltd
The content is shown in English
Methermat 0.2mg Injection image

Product introduction

Methermat 0.2mg Injection is taken by mouth with or without food preferably at night. However, take it at the same time each day as this helps to maintain consistent level of medicine in the body. Do not skip any doses and finish the full course of treatment even if you feel better. In case you have missed a dose, take it as soon as you remember it. You should continue to take this medicine for as long as the doctor advises and do not stop taking it suddenly as it may result in worsening of headaches.

Side effects associated with the use of this medicine includes nausea, vomiting, muscle pain and leg pain. It may cause dizziness, so do not drive, operate machinery, until you know how this medicine affects you.

Uses of Methermat Injection

Side effects of Methermat Injection

Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them
Common side effects of Methermat
  • Nausea
  • Vomiting
  • Muscle pain
  • Leg pain

How to use Methermat Injection

Your doctor or nurse will give you this medicine. Kindly do not self administer.

How Methermat Injection works

Migraine headaches are thought to result from the dilatation of blood vessels in the head. Methermat 0.2mg Injection is a serotonin receptor antagonist. It works by maintaining the level of serotonin (chemical messenger) in the brain, thus prevents the transmission of pain. It also inhibits the production of pro-inflammatory neuropeptide (chemical messenger) which is responsible for migraine pain. Again, it works on the activation of 5-HT1D receptors to narrow down the blood vessels to alleviate the pain.

Quick tips

  • Methermat 0.2mg Injection helps in the treatment of an acute attack of migraine.
  • Take it as soon as you notice the first sign of migraine. 
  • Some tips that may help avoid a migraine attack:
    • Have your meals at the same time everyday
    • Avoid bright lights and extreme temperatures
    • Avoid loud music and noisy places
    • Avoid chocolates,  cheese, processed food, alcohol and smoking
    • Get sufficient sleep and avoid stress
  • It should be taken at night-time before going to bed.
  • It may cause sleepiness. Do not drive or do anything that requires mental focus until you know how Methermat 0.2mg Injection affects you.
  • Do not stop taking the medication suddenly as it can cause worsening of headaches.

Safety advice

Alcohol

Alcohol

CONSULT YOUR DOCTOR
It is not known whether it is safe to consume alcohol with Methermat 0.2mg Injection. Please consult your doctor.
Pregnancy

Pregnancy

UNSAFE
Methermat 0.2mg Injection is highly unsafe to use during pregnancy. Seek your doctor's advice as studies on pregnant women and animals have shown significant harmful effects to the developing baby.
Breast feeding

Breast feeding

UNSAFE
Methermat 0.2mg Injection is unsafe to use during breastfeeding. Data suggests that the drug may cause toxicity to the baby.
Driving

Driving

UNSAFE
Methermat 0.2mg Injection may decrease alertness, affect your vision or make you feel sleepy and dizzy. Do not drive if these symptoms occur.
Kidney

Kidney

CONSULT YOUR DOCTOR
There is limited information available on the use of Methermat 0.2mg Injection in patients with kidney disease. Please consult your doctor.
Liver

Liver

CONSULT YOUR DOCTOR
There is limited information available on the use of Methermat 0.2mg Injection in patients with liver disease. Please consult your doctor.

Frequently asked questions

Methermat 0.2mg Injection should not be used regularly even if you adhere to the prescribed dosage. It should not be used for prevention of migraine. There is a risk of developing ergotism which may result in decreased blood supply to the brain and may cause limb weakness, blurred vision, and slurred speech.
Take one tablet at the first sign of migraine. If the headache does not stop within 30 minutes, take half or one more tablet. Take half or one tablet every 30 minutes until the headache stops or you have taken the maximum of 3 tablets. If the headache still continues, contact your doctor. It is not recommended to take more than three tablets (6 mg) in 24 hours or 6 tablets (12 mg) in 1 week. Consult your doctor if more medicine is required.
The symptoms of overdosage of Methermat 0.2mg Injection may include vomiting, numbness, tingling sensation, pain, blue hands and feet. Additionally, there may be a lack of pulse , dizziness or lightheadedness, faintness, drowsiness, unconsciousness, and even coma and seizures. The stomach of such patients should be cleared if vomiting has not occurred.
It is important not to take zolmitriptan, almotriptan, sumatriptan, rizatriptan, and frovatriptan for 24 hours after taking Methermat 0.2mg Injection. In addition, do not take Methermat 0.2mg Injection for 6 hours after taking any of these medicines. Eletriptan (also used to treat migraine) and Methermat 0.2mg Injection should not be taken within 24 hours of each other.
The serious side effects of Methermat 0.2mg Injection include leg weakness, chest pain, rapid or slow heartbeat, dizziness, and muscle pain in the legs or arms. Methermat 0.2mg Injection may also cause blue hands and feet, swelling, itching, pain, burning, or tingling in the fingers and toes. Call your doctor immediately if you experience any of these symptoms.
Yes, Methermat 0.2mg Injection may cause dependence. It should not be used on a regular basis or to prevent a migraine attack. Its regular use can cause dependence and rebound headaches which in turn may lead you to take Methermat 0.2mg Injection more often.
Grapefruit juice should be avoided while taking Methermat 0.2mg Injection as it can increase the risk of side effects. Do not smoke or drink alcohol while taking this medicine. If you feel drowsy after taking Methermat 0.2mg Injection do not drive or use heavy machinery. Also, you should avoid getting pregnant and breastfeeding your baby, as Methermat 0.2mg Injection may have harmful effects on the baby.
Methermat 0.2mg Injection is obtained from Claviceps species, mainly from clavicles purpurea.
Methermat 0.2mg Injection belongs to ergot alkaloid class of medicines. It works by preventing blood vessels in the head from expanding and causing headaches.

Fact Box

Chemical Class

Ergot Derivative

Habit Forming

No

Therapeutic Class

NEURO CNS

Action Class

Ergot derivative

References

  1. Katzung BG. Histamine, Serotonin, & the Ergot Alkaloids. In: Katzung BG, Masters SB, Trevor AJ, editors. Basic and Clinical Pharmacology. 11th ed. New Delhi, India: Tata McGraw Hill Education Private Limited; 2009. p. 288.
  2. Briggs GG, Freeman RK, editors. A Reference Guide to Fetal and Neonatal Risk: Drugs in Pregnancy and Lactation. 10th ed. Philadelphia, PA: Wolters Kluwer Health; 2015. pp. 486-88.
  3. Drugs.com. Ergotamine. [Accessed 25 Mar. 2019] (online) Available from:
  4. Chaves RG, Lamounier JA. Breastfeeding and maternal medications. J Pediatr (Rio J). 2004;80(5 Suppl):S189-S198. [Accessed 20 Mar. 2019] (online) Available from:
  5. PubChem. Ergotamine. [Accessed on 25 Mar. 2019] (online) Available from:
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Patient concerns

I am facing issue of headache from last 3-4 years.i have consulted allopathy and they have given me sibelum 10 for migrane and asked to take metopar(paracetamol) when ever pain is too much.i am nit taking sibelum now but i am taking metopar when ever required.so i want a homeopathy consultatation if it can be cured by homeopathy or the level of headache can be lowered. Currently i face headache once in a week and i had to take metopar. Kindly suggest. My weight 80 kg And i am taking some neuro medicines ( stalopam 10, amitone 10) I also have cholesterol and taking (atorec 20)

Dr. Faran Siddiqui
Dr. Faran Siddiqui
Homeopathy
Migraine and headache are two different things migraine is primarily headache of one side in symmetrically

He has a problem of headache.what is the reason of headache in childMRI nd all reports are normal

Dr. Gopal Samdani
Dr. Gopal Samdani
Paediatrics
Migraine, Tension-type headache, Cluster headache and Chronic daily headache are few examples of reason
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Disclaimer

Tata 1mg's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover everything about particular health conditions, lab tests, medicines, all possible side effects, drug interactions, warnings, alerts, etc. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.

Marketer details

Name: Makers Laboratories Ltd
Address: 54-D, Government Industrial Estate, Charkop, Kandivali (W). , Mumbai, Maharashtra

Vendor Details

Country of origin: India
A licensed vendor partner from your nearest location will deliver Methermat 0.2mg Injection. Once the pharmacy accepts your order, the details of the pharmacy will be shared with you. Acceptance of your order is based on the validity of your doctor's ℞ and the availability of this medicine.

In case of any issues, contact us

Email ID: [email protected]
Phone Number: 0124-4166666
Address: 5th Floor Tower - B of the Presidency Building, 46/4 Mehrauli Gurgaon Road, Sector 14, Gurugram, Haryana-122001, India

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Most medicines cannot be sold without a valid prescription, as per the Drugs and Cosmetics Act, 1940 and Rules, 1945
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