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Metsep 2 Tablet

Written By Dr. Betina Chandolia, MDS, BDS
Reviewed By Dr. Lalit Kanodia, MBA, MD Pharmacology
Last updated on 30 Oct 2024 | 01:11 AM (IST)
Metsep 2 Tablet belongs to a group of medicines called sulfonylureas and is used to treat type 2 diabetes mellitus in adults. It helps control blood sugar levels in people with diabetes thereby preventing serious complications of diabetes such as kidney damage and blindness.
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General Information

The content is shown in English
Metsep 2 Tablet image

Product introduction

Metsep 2 Tablet may be used alone or along with other medicines. It should be taken just before or with the first meal of the day. Take it regularly at the same time each day to get the maximum benefit. Your doctor will decide what dose is best for you and this may change from time to time according to your blood sugar levels.

Keep taking Metsep 2 Tablet, even if you feel well or your blood sugar levels are controlled. If you stop it without consulting your doctor, your blood sugar levels could rise to put you at risk of diabetes complications such as kidney damage, blindness, nerve problems, and loss of limbs. Remember that it is only part of a treatment program that should also include a healthy diet, regular exercise, and weight reduction as advised by your doctor. Your lifestyle plays a big part in controlling diabetes.

The most common side effects of taking Metsep 2 Tablet include low blood sugar levels (hypoglycemia), nausea, headache, weakness, and dizziness. Make sure you recognize the signs of having low blood sugar levels, such as sweating, dizziness, headache, and shaking, and know how to deal with them. To prevent this, it is important to have regular meals and always carry a fast-acting source of glucose such as sugary food or fruit juice with you. Drinking alcohol can also increase your risk of low blood sugar levels and hence should be avoided. Some people may experience an increase in weight with this medicine.

You should not take Metsep 2 Tablet if you have type 1 diabetes mellitus, diabetic ketoacidosis (high levels of acid in your blood), or if you have severe kidney or liver disease. Before taking this medicine, tell your doctor if you have ever had heart disease, thyroid disease, or some hormonal conditions, as it may not be suitable. Pregnant or breastfeeding women should also consult their doctor before taking it. Your blood sugar levels should be checked regularly and your doctor may also advise blood tests to monitor your blood cell counts and liver function.

Uses of Metsep Tablet

Side effects of Metsep Tablet

Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them
Common side effects of Metsep
  • Hypoglycemia (low blood glucose level)
  • Headache
  • Nausea
  • Dizziness
  • Weakness

How to use Metsep Tablet

Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Metsep 2 Tablet is to be taken with food.

How Metsep Tablet works

Metsep 2 Tablet is an antidiabetic medication. It works by increasing the amount of insulin released by the pancreas in order to lower blood glucose.

Quick tips

  • Take Metsep 2 Tablet shortly before or with the first main meal of the day (usually breakfast).
  • Exercise regularly, eat a healthy diet and take your other diabetes medicines (if prescribed) alongside.
  • Monitor your blood sugar level regularly while you are taking Metsep 2 Tablet.
  • Metsep 2 Tablet can cause hypoglycemia (low blood sugar level) when used with other antidiabetic medicines, alcohol or if you delay or miss a meal.
  • Be careful while driving or operating machinery until you know how Metsep 2 Tablet affects you.
  • Always carry some sugary food or fruit juice with you in case you experience hypoglycemic symptoms such as cold sweats, cool pale skin, tremor and anxiety.
  • Your doctor may check your liver function regularly. Inform your doctor if you develop symptoms, such as abdominal pain, loss of appetite, or yellowing of the eyes or skin (jaundice).

Safety advice

Alcohol

Alcohol

UNSAFE
It is unsafe to consume alcohol with Metsep 2 Tablet.
Pregnancy

Pregnancy

CONSULT YOUR DOCTOR
Metsep 2 Tablet may be unsafe to use during pregnancy. Although there are limited studies in humans, animal studies have shown harmful effects on the developing baby. Your doctor will weigh the benefits and any potential risks before prescribing it to you. Please consult your doctor.
Breast feeding

Breast feeding

CONSULT YOUR DOCTOR
Metsep 2 Tablet is probably unsafe to use during breastfeeding. Limited human data suggests that the drug may pass into the breastmilk and harm the baby.
Monitoring of the breastfed infant's blood glucose is advisable during maternal therapy with Metsep 2 Tablet
Driving

Driving

CAUTION
Your ability to drive may be affected if your blood sugar is too low or too high. Do not drive if these symptoms occur.
Kidney

Kidney

CAUTION
Metsep 2 Tablet should be used with caution in patients with kidney disease. Dose adjustment of Metsep 2 Tablet may be needed. Please consult your doctor.
Use of Metsep 2 Tablet is not recommended in patients with severe kidney disease. These patients can experience very low blood sugar levels which may become normal after a long time.
Liver

Liver

CAUTION
Metsep 2 Tablet should be used with caution in patients with liver disease. Dose adjustment of Metsep 2 Tablet may be needed. Please consult your doctor.
However, the use of Metsep 2 Tablet is not recommended in patients with severe liver disease. These patients can experience very low blood sugar levels which may become normal after a long time.

Frequently asked questions

The recommended starting dose of Metsep 2 Tablet is 1 mg or 2 mg once daily, administered with breakfast. If you are at a higher risk of low blood sugar (e.g., the elderly or patients with renal impairment), you will be given a starting dose of 1 mg once daily. The usual maintenance dose is 1–4 mg once daily. The maximum recommended dose is 8 mg once daily. After reaching a daily dose of 2 mg, the dosage will be increased not more than 2 mg at 1- to 2-week intervals, based on your blood glucose level.
Metsep 2 Tablet itself does not cause sleepiness. However, it may cause hypoglycemia (low blood sugar) when used with other anti-diabetes medicine. Because of this you may feel sleepy or have problems in sleeping.
Metsep 2 Tablet does not affect kidneys in patients with normal kidney function. However, its use should be avoided in patients with severe kidney disease since Metsep 2 Tablet is principally eliminated by the kidneys.
No, it is not known that Metsep 2 Tablet causes memory loss. However, the use of Metsep 2 Tablet may cause low blood sugar which may cause problems with concentration and reduced alertness.
Metsep 2 Tablet should be avoided by patients who are allergic to it, have severe kidney or liver disease, have G6PD-deficiency (an inherited condition affecting red blood cells) or are due to have surgery. Additionally, patients who are trying to get pregnant, are pregnant or breastfeeding, or have insulin-dependent diabetes (type 1 diabetes mellitus) should avoid taking Metsep 2 Tablet.
Metsep 2 Tablet takes about 2 to 3 hours to reduce blood sugar levels. You may not feel any difference, but this does not mean the medicine is not working. Continue taking the medication as directed by your doctor and if you have any concerns, discuss it with your doctor.
Usually, the treatment for diabetes is suggested for a long term. You may have to continue the treatment life long. Metsep 2 Tablet only controls the sugar levels but does not cure it. Do not stop taking Metsep 2 Tablet without talking to your doctor. If you stop taking Metsep 2 Tablet suddenly your diabetes may get worse.
No. Taking Metsep 2 Tablet on an empty stomach can cause your blood sugar levels to become too low. Low blood sugar can cause dizziness, shaking, anxiety, irritability, a fast heartbeat, and confusion. Therefore, you should always take the medicine with breakfast or the first meal of the day. If you are skipping your meal, then you should also avoid taking Metsep 2 Tablet.
Yes, Metsep 2 Tablet can cause weight gain. Metsep 2 Tablet is a sulfonylurea drug and causes the pancreas to release insulin. It may stimulate hunger and cause mild weight gain in some people. Patients are advised to eat a healthy balanced diet and exercise regularly to keep their weight stable.
Yes, Metsep 2 Tablet can cause dizziness as a side effect. If this happens to you, sit or lie down until the symptoms pass. Always carry some sugary food or fruit juice with you in case you experience dizziness while travelling.
It is advisable to avoid foods that are high in saturated and trans fats, instead consume fats from fish and nuts. Control your carbohydrate intake as this directly affects your blood sugar.
Yes, Metsep 2 Tablet tablet is safe when used as directed by the doctor. However, it may show some side effects. For best results, it should be used in the correct dose and at the same time each day.
Yes, people with diabetes must include proteins along with other essential nutrients in their daily diet. Proteins are one of the major energy providers among all essential nutrients. Besides, being the building blocks of the human body, proteins break down into glucose to release energy. Unlike carbohydrates, the metabolism of proteins into glucose is much slower. Therefore, the release of energy usually takes a few hours after consumption. Thus, the spike in blood sugar levels might occur after a few hours when you are on a high-protein diet.
No, artificial sweeteners are not good for people with diabetes. They are composed of chemicals that can cause mild to severe side effects. Thus, it is better to limit or avoid their use as much as you can.
Yes, uncontrolled diabetes can cause kidney failure. In the long run, diabetes can affect the kidneys leading to a condition called diabetic nephropathy. Diabetic nephropathy is a condition that is a major cause of kidney failure in patients with diabetes. The best way to prevent damage to kidneys is by keeping diabetes in check, making dietary changes, monitoring sugar levels regularly, getting routine blood tests done, and taking prescribed medications on time.
Diabetes is a condition that causes changes in your blood glucose levels, which if left uncontrolled, can lead to serious health complications affecting the heart, brain, kidneys, and eyes. However, with simple lifestyle changes, diet, and medications, one can manage their condition and lead a healthy life.

Fact Box

Chemical Class

Third-generation Sulfonylurea Derivative

Habit Forming

No

Therapeutic Class

ANTI DIABETIC

Action Class

Sulfonylureas (Insulin Secretagogues)

References

  1. Powers AC, D’Alessio D. Endocrine Pancreas and Pharmacotherapy of Diabetes Mellitus and Hypoglycemia. In: Brunton LL, Chabner BA, Knollmann BC, editors. Goodman & Gilman’s: The Pharmacological Basis of Therapeutics. 12th ed. New York, New York: McGraw-Hill Medical; 2011. pp. 1255-1257.
  2. Nolte MS. Pancreatic hormones and antidiabetic drugs. In: Katzung BG, Masters SB, Trevor AJ, editors. Basic and Clinical Pharmacology. 11th ed. New Delhi, India: Tata McGraw Hill Education Private Limited; 2009. pp. 740.
  3. Briggs GG, Freeman RK, editors. A Reference Guide to Fetal and Neonatal Risk: Drugs in Pregnancy and Lactation. 10th ed. Philadelphia, PA: Wolters Kluwer Health; 2015. pp. 629-30.
  4. Glimepiride. Bridgewater, New Jersey: Sanofi-Aventis U.S. LLC.; 2009. [Accessed 13 Mar. 2019] (online) Available from:
  5. DailyMed. Glimepiride [Drug Label Information]. [Accessed 20 Sept. 2021] (online) Available from:
  6. National Health Services. How and when to take glimepiride. [Last reviewed: 14 Mar. 2022]. [Accessed 28 June 2023]. (online) Available from:
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Patient concerns

Diabetes mellitus type 2 ,thirst

Dr. Sanjay Bhatt
Dr. Sanjay Bhatt
Physician
A person can control his or her sugar levels by doing regular exercise and walk or regular aerobic exercises at least 30 to 45 minutes per day.MEDICAL NUTRITIONAL THERAPY THAT IS TO MAINTAIN CALORIES INTAKE AS PER BMI .TAKE HELP OF DIABETIC EDUCATOR. VISIT YOUR DOCTOR AND FOLLOW ALL WHAT DOCTOR SUGGESTED.IN TIME ALL ROUTINE INVESTIGATIONS SHOULD BE DONE.you should not treat it as disease but a start of a healthy life.Uncontrolled sugar levels for long time leads to lower limb weakness which is neuropathy and which is followed by foot ulcers and other complications like kidney or heart problems .online prescription is not allowed without seeing pt.so contact doctor nearby for any change or dose adjustment or visit my clinic at gurgaon sector 52 RdCity snergy multi speciality clinic near SRS MARKET

Diabetes mellitus type 2 required only ayurvedic medicine

Dr. Sanjay Bhatt
Dr. Sanjay Bhatt
Physician
Go for allopathic medicine
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Disclaimer

Tata 1mg's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover everything about particular health conditions, lab tests, medicines, all possible side effects, drug interactions, warnings, alerts, etc. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.

Marketer details

Name: Sepik Life Sciences
Address: 315,First Floor, Ind. Area Phase 2, Panchkula, 134113, Haryana,India

Vendor Details

Country of origin: India
A licensed vendor partner from your nearest location will deliver Metsep 2 Tablet. Once the pharmacy accepts your order, the details of the pharmacy will be shared with you. Acceptance of your order is based on the validity of your doctor's ℞ and the availability of this medicine.

In case of any issues, contact us

Email ID: [email protected]
Phone Number: 0124-4166666
Address: 5th Floor Tower - B of the Presidency Building, 46/4 Mehrauli Gurgaon Road, Sector 14, Gurugram, Haryana-122001, India
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