Mirator 0.125 Tablet
Written By Dr. Swati Mishra, BDS
Reviewed By Dr. Varun Gupta, MD Pharmacology, MBBS
Last updated on 12 Nov 2024 | 01:04 AM (IST)
Mirator 0.125 Tablet is used in the treatment of Parkinson's disease and restless leg syndrome (an urge to move the legs usually accompanied or caused by uncomfortable and unpleasant leg sensations). It helps to treat excessive shaking by slowing down the body movements.
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General Information
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Product introduction
Mirator 0.125 Tablet should be taken with food. However, take it at the same time each day as this helps to maintain a consistent level of medicine in the body. Take this medicine in the dose and duration as advised by your doctor and if you have missed a dose, take it as soon as you remember it. You should never skip any doses and finish the full course of treatment even if you feel better. This medication must not be stopped suddenly without talking to your doctor.
Some common side effects of this medicine include nausea, dry mouth, fatigue, hallucinations, constipation, and peripheral edema. It also causes dizziness and sleepiness, so do not drive or do anything that requires mental focus until you know how this medicine affects you. Inform your doctor if you develop any unusual changes in mood, an abnormally high sex drive, an urge to gamble, or uncontrolled spending as these may prove very harmful.
Some common side effects of this medicine include nausea, dry mouth, fatigue, hallucinations, constipation, and peripheral edema. It also causes dizziness and sleepiness, so do not drive or do anything that requires mental focus until you know how this medicine affects you. Inform your doctor if you develop any unusual changes in mood, an abnormally high sex drive, an urge to gamble, or uncontrolled spending as these may prove very harmful.
Uses of Mirator Tablet
Benefits of Mirator Tablet
Parkinson's disease
Mirator 0.125 Tablet is effective in relieving symptoms of Parkinson's disease such as tremors, muscle stiffness, and difficulty moving. It increases the amount of a chemical called dopamine in the brain which helps in the coordination of body movements. This medicine can therefore enhance the quality of life by improving the ability to carry out daily functions in a better manner.
Mirator 0.125 Tablet is effective in relieving symptoms of Parkinson's disease such as tremors, muscle stiffness, and difficulty moving. It increases the amount of a chemical called dopamine in the brain which helps in the coordination of body movements. This medicine can therefore enhance the quality of life by improving the ability to carry out daily functions in a better manner.
Restless leg syndrome
Restless leg syndrome is a condition that causes an uncontrollable urge to move your legs, usually because of an uncomfortable sensation. It typically happens in the evening or nighttime hours when you're sitting or lying down. Moving or walking, that is change in posture, will control the unpleasant feeling temporarily. Mirator 0.125 Tablet helps to relieve this uncomfortable urge and calms these sensations. Take it as advised by the doctor to get the maximum relief.
Restless leg syndrome is a condition that causes an uncontrollable urge to move your legs, usually because of an uncomfortable sensation. It typically happens in the evening or nighttime hours when you're sitting or lying down. Moving or walking, that is change in posture, will control the unpleasant feeling temporarily. Mirator 0.125 Tablet helps to relieve this uncomfortable urge and calms these sensations. Take it as advised by the doctor to get the maximum relief.
Side effects of Mirator Tablet
Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them
Common side effects of Mirator
- Dizziness
- Sleepiness
- Nausea
- Dryness in mouth
- Fatigue
- Hallucination
- Constipation
- Peripheral edema
- Muscle spasm
How to use Mirator Tablet
Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Mirator 0.125 Tablet is to be taken with food.
How Mirator Tablet works
Mirator 0.125 Tablet works by mimicking the action of dopamine, a chemical messenger that is needed to control movement in the brain.
All substitutes for Mirator 0.125 Tablet
For information purposes only. Consult a doctor before taking any medicine.
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Quick tips
- You have been prescribed Mirator 0.125 Tablet to treat your symptoms of Parkinson's disease and/or restless leg syndrome.
- It can be taken with or without food. Taking it with food may reduce nausea.
- For restless leg syndrome, take this medicine 2 to 3 hours before bedtime.
- Avoid activities that require you to be alert, such as driving a car until you know how this medication affects you.
- When you first start taking Mirator 0.125 Tablet, it may cause sudden drop in your blood pressure when you change positions. To lower the chance of feeling dizzy or passing out, rise slowly if you have been sitting or lying down.
- Talk to your doctor in case you develop hallucinations or other changes in your behavior.
- Inform your doctor if you develop compulsive behaviors that are hard to control, such as binge eating, gambling, spending money, and sexual urges.
- Do not stop taking the medication suddenly without talking to your doctor.
Safety advice

Alcohol
UNSAFE
Mirator 0.125 Tablet may cause excessive drowsiness with alcohol.

Pregnancy
CONSULT YOUR DOCTOR
Mirator 0.125 Tablet may be unsafe to use during pregnancy. Although there are limited studies in humans, animal studies have shown harmful effects on the developing baby. Your doctor will weigh the benefits and any potential risks before prescribing it to you. Please consult your doctor.

Breast feeding
CONSULT YOUR DOCTOR
Mirator 0.125 Tablet is probably unsafe to use during breastfeeding. Limited human data suggests that the drug may pass into the breastmilk and harm the baby.
Mirator 0.125 Tablet suppresses serum prolactin and may interfere with breastfeeding.
Mirator 0.125 Tablet suppresses serum prolactin and may interfere with breastfeeding.

Driving
UNSAFE
Mirator 0.125 Tablet may cause side effects which could affect your ability to drive.
Mirator 0.125 Tablet can cause hallucinations (seeing, hearing or feeling things that are not there). This may affect your ability to drive.
Mirator 0.125 Tablet can cause hallucinations (seeing, hearing or feeling things that are not there). This may affect your ability to drive.

Kidney
CAUTION
Mirator 0.125 Tablet should be used with caution in patients with kidney disease. Dose adjustment of Mirator 0.125 Tablet may be needed. Please consult your doctor.

Liver
SAFE IF PRESCRIBED
Mirator 0.125 Tablet is probably safe to use in patients with liver disease. Limited data available suggests that dose adjustment of Mirator 0.125 Tablet may not be needed in these patients. Please consult your doctor.
Frequently asked questions
A common side effect of Mirator 0.125 Tablet is decrease in body weight which may be due to decrease in appetite. Uncommonly, it can also cause increase in weight. However, if you have concerns regarding your weight talk to your doctor or a nutritionist.
Yes, Mirator 0.125 Tablet may cause sleepiness. You may also experience sudden episodes of falling asleep. If it occurs, restrict driving and using heavy machinery and inform your doctor.
Restless leg syndrome (RLS) is a condition that causes discomfort in the legs and a strong urge to move the legs, especially at night and when sitting or lying down. Mirator 0.125 Tablet belongs to dopamine (neurotransmitter) agonist class of medicines. It acts by stimulating the dopamine receptors which is needed in the brain to control movement. Hence, it is used to improve RLS.
No, Mirator 0.125 Tablet is not a muscle relaxant. It helps in improving movements and muscle control in Parkinson’s disease. It is a dopamine agonist and acts on dopamine receptors.
You should not stop Mirator 0.125 Tablet without talking to your doctor. Sudden discontinuation of Mirator 0.125 Tablet may cause neuroleptic malignant syndrome. The symptoms of malignant syndrome include loss of muscle movement, rigid muscles, fever, unstable blood pressure, increased heart rate, confusion, and depressed level of consciousness.
You should take Mirator 0.125 Tablet as directed by your doctor. The doctor will decide your dose depending on the condition you are being treated for. Preferably it should be taken 2-3 hours before bedtime. Swallow the tablets whole with water. It can be taken with or without food, but taking it with food may help reduce the chances of nausea.
The serious side effects of Mirator 0.125 Tablet include hallucinations (seeing things or hearing voices that do not exist), confusion, aggressive behavior, agitation, abnormal thoughts, changes in vision, abnormal body movements, and motions that you cannot control. It may also cause changes in the way you sit or stand that you cannot control, such as your neck bending forward, bending forward at the waist, or tilting sideways when you sit, stand or walk. Additionally, it may cause dark, red or cola-colored urine, muscle tenderness, muscle stiffness or aching and muscle weakness. Call your doctor immediately if you experience any of these.
Mirator 0.125 Tablet may cause impulse control disorders in which you may have cravings or urge to behave in an unusual manner, which normally you would not do. Mirator 0.125 Tablet may also make it hard for you to resist the impulse to carry certain activities which can harm you or others, like addictive gambling, excessive eating or spending money. Along with that, it may cause an abnormally high sex drive or preoccupation with an increase in sexual thoughts or feelings.
Fact Box
Chemical Class
Benzothiazole Derivative
Habit Forming
No
Therapeutic Class
NEURO CNS
Action Class
Dopamine agonists
References
- Aminoff MJ. Pharmacologic Management of Parkinsonism & Other Movement Disorders. In: Katzung BG, Masters SB, Trevor AJ, editors. Basic and Clinical Pharmacology. 11th ed. New Delhi, India: Tata McGraw Hill Education Private Limited; 2009. pp. 475-76.
- Briggs GG, Freeman RK, editors. A Reference Guide to Fetal and Neonatal Risk: Drugs in Pregnancy and Lactation. 10th ed. Philadelphia, PA: Wolters Kluwer Health; 2015. pp. 1140-41.
- Pramipexole dihydrochloride. Ridgefield, Connecticut: Boehringer Ingelheim International GmbH; 2010. [Accessed 22 Jan. 2019] (online) Available from:
- Chaves RG, Lamounier JA. Breastfeeding and maternal medications. J Pediatr (Rio J). 2004;80(5 Suppl):S189-S198. [Accessed 22 Mar. 2019] (online) Available from:
- Pramipexole. South Ruislip, Middlesex: Aurobindo Pharma - Milpharm Ltd.; 2012 [revised 7 Feb. 2018]. [Accessed 22 Mar. 2019] (online) Available from:
- Central Drugs Standard Control Organisation (CDSCO). [Accessed 07 Aug. 2023] (online) Available from:
- Pramipexole dihydrochloride [Prescribing Information]. Ridgefield, CT: Boehringer Ingelheim Pharmaceuticals, Inc.; 2021. [Accessed 05 Aug. 2023] (online) Available from:
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User feedback
Once A Day
47%
Twice A Day
28%
Thrice A Day
23%
Once A Month
2%
Parkinson's disease
33%
Restless leg syndrome
33%
Others
33%
Poor
100%
Nausea
33%
Fatigue
33%
Dryness in mouth
33%
With food
100%
Average
100%
Patient concerns
Restless leg syndrome with irritable bowel syndrome
Dr. Pushkar Mani
Physician
take cobadex czs once daily for 1 monthevion 400 mg once daily for 1 month
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Dr. Shallu Garg
Pain and Stress Management
Ashwagandharishtam 15-15 ml twice a day with equal quantity of water
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Marketer details
Name: Torrent Pharmaceuticals Ltd
Address: Off. Ashram Road, Ahmedabad - 380 009., Gujarat, India
Address: Off. Ashram Road, Ahmedabad - 380 009., Gujarat, India
Vendor Details
Country of origin: India
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