Mistabron 600mg Injection
Written By Dr. Shreya Gupta, MDS (Oral Pathology & Microbiology), BDS
Reviewed By Dr. Ashish Ranjan, MD (Pharmacology), MBBS
Last updated on 30 Oct 2024 | 12:16 PM (IST)
Mistabron 600mg Injection is used to prevent ifosfamide-induced hemorrhagic cystitis (bleeding in the bladder that may be caused as a side effect due to treatment with a cancer chemotherapy drug called ifosfamide). However, it is not used to reduce the risk of bladder bleeding due to other medical conditions.
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General Information
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Product introduction
Mistabron 600mg Injection is given under the supervision of a doctor. The dose and duration of the treatment vary based on your need and response to treatment. You should take it exactly as your doctor has advised. Taking it in the wrong way or taking too much can cause very serious side effects. It may take several weeks or months for you to see or feel the benefits but do not stop taking it unless your doctor tells you to.
Some common side effects of this medicine include nausea, headache, lightheadedness, lethargy, and abdominal pain. It is advised to drink at least 1 liter of fluid daily when you are on treatment with this medicine. You should seek immediate medical attention if you experience signs of severe allergic reactions like rash, itching, breathing difficulty, chest tightness, and swelling of the mouth, face, lips, or tongue while taking this medicine. Regular blood tests are required to check your blood cells along with the kidney, liver, and blood uric acid levels.
Before taking it, tell your doctor if you have an autoimmune disorder, liver, or kidney problems or are taking any medicines to treat infections. Many other medicines can affect, or be affected by, this medicine so let your doctor know all medications you are using. This medicine is not recommended during pregnancy or while breastfeeding. The use of effective contraception by both males and females during treatment is important to avoid pregnancy.
Some common side effects of this medicine include nausea, headache, lightheadedness, lethargy, and abdominal pain. It is advised to drink at least 1 liter of fluid daily when you are on treatment with this medicine. You should seek immediate medical attention if you experience signs of severe allergic reactions like rash, itching, breathing difficulty, chest tightness, and swelling of the mouth, face, lips, or tongue while taking this medicine. Regular blood tests are required to check your blood cells along with the kidney, liver, and blood uric acid levels.
Before taking it, tell your doctor if you have an autoimmune disorder, liver, or kidney problems or are taking any medicines to treat infections. Many other medicines can affect, or be affected by, this medicine so let your doctor know all medications you are using. This medicine is not recommended during pregnancy or while breastfeeding. The use of effective contraception by both males and females during treatment is important to avoid pregnancy.
Uses of Mistabron Injection
Benefits of Mistabron Injection
Treatment of Ifosfamide-induced hemorrhagic cystitis
Ifosfamide-induced hemorrhagic cystitis is an inflammatory condition due to the use of a medicine called Ifosfamide that causes bleeding in the bladder. Mistabron 600mg Injection helps to suppress the body’s immune system, thereby reducing the progression of the disease. It reduces the inflammation of the damaged area, prevents further damage, and stabilises your condition
Ifosfamide-induced hemorrhagic cystitis is an inflammatory condition due to the use of a medicine called Ifosfamide that causes bleeding in the bladder. Mistabron 600mg Injection helps to suppress the body’s immune system, thereby reducing the progression of the disease. It reduces the inflammation of the damaged area, prevents further damage, and stabilises your condition
How to use Mistabron Injection
Your doctor or nurse will give you this medicine. Kindly do not self administer.
How Mistabron Injection works
Mistabron 600mg Injection helps to reduce the risk of inflammation and bleeding in the bladder, who receive ifosfamide (a medicine used to treat cancer).
Quick tips
- Mistabron 600mg Injection is given as in injection or infusion under the supervision of a doctor only.
- Do not skip any dose and complete the course as suggested by your doctor.
- It is advisable to drink plenty of water to stay hydrated while taking this medicine.
- Your doctor may get a regular urine and blood tests done to monitor your blood cell count (CBC).
Safety advice

Alcohol
CONSULT YOUR DOCTOR
It is not known whether it is safe to consume alcohol with Mistabron 600mg Injection. Please consult your doctor.

Pregnancy
SAFE IF PRESCRIBED
Mistabron 600mg Injection is generally considered safe to use during pregnancy. Animal studies have shown low or no adverse effects to the developing baby; however, there are limited human studies.

Breast feeding
UNSAFE
Mistabron 600mg Injection is unsafe to use during breastfeeding. Data suggests that the drug may cause toxicity to the baby.

Driving
UNSAFE
Mistabron 600mg Injection may cause side effects which could affect your ability to drive.
As patients undergoing treatment with Mistabron 600mg Injection may experience undesirable effects such as lightheadedness, lethargy, dizziness, and blurred vision which could affect the ability to drive.
As patients undergoing treatment with Mistabron 600mg Injection may experience undesirable effects such as lightheadedness, lethargy, dizziness, and blurred vision which could affect the ability to drive.

Kidney
CAUTION
Mistabron 600mg Injection should be used with caution in patients with kidney disease. Dose adjustment of Mistabron 600mg Injection may be needed. Please consult your doctor.

Liver
CAUTION
Mistabron 600mg Injection should be used with caution in patients with liver disease. Dose adjustment of Mistabron 600mg Injection may be needed. Please consult your doctor.

Frequently asked questions
It is given along with the chemotherapy drug ifosfamide or cyclophosphamide to reduce the side effects of these drugs
Yes, Mesna is compatible with potassium chloride and doxorubicin
Mistabron 600mg Injection is not a chemotherapy drug
No. Mistabron 600mg Injection is not cytotoxic drug. It is cytoprotective drug
No, Mistabron 600mg Injection is not a vesicant.
Fact Box
Chemical Class
Sulfhydryl compound, {organosulfonic acid}
Habit Forming
No
Therapeutic Class
BLOOD RELATED
Action Class
Cytoprotective agents- Bladder
References
- Briggs GG, Freeman RK, editors. A Reference Guide to Fetal and Neonatal Risk: Drugs in Pregnancy and Lactation. 10th ed. Philadelphia, PA: Wolters Kluwer Health; 2015. pp. 870-71.
- Mesna. Thetford, Norfolk: Baxter Healthcare Ltd.; 2003 [revised Oct. 2014]. [Accessed 28 Jan. 2019] (Online) Available from:
- Mesna. Los Angeles, California: American pharmaceutical partners; 2001. [Accessed 26 Mar. 2019] (online) Available from:
- Medscape. Mesna. [Accessed 26 Mar. 2019] (online) Available from:

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Patient concerns
Cystitis, left renal calculi. .
Dr. Aanchal Maheshwari
Ayurveda
Take tablet neeri , tablet cystone, tablet chandraprabha vati all 3, 2 tablet twice daily water. Drink more of water
Cystitis, frequent urination , pain at urinary bladder site
Dr. Praveen Pushkar
Urology
Get urine routine examination n culture done
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Tata 1mg's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover everything about particular health conditions, lab tests, medicines, all possible side effects, drug interactions, warnings, alerts, etc. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.
Marketer details
Name: UCB India Pvt Ltd
Address: 504, Peninsula Towers, Peninsula Corporate Park, Ganpatrao Kadam Marg, Lower Parel, IND - Mumbai 400 013
Address: 504, Peninsula Towers, Peninsula Corporate Park, Ganpatrao Kadam Marg, Lower Parel, IND - Mumbai 400 013
Vendor Details
Country of origin: India
Lab tests offered by us
- CBC (Complete Blood Count)
- FBS (Fasting Blood Sugar)
- Thyroid Profile Total (T3, T4 & TSH)
- HbA1c (Glycosylated Hemoglobin)
- Glucose - Postprandial
- Lipid Profile
- Vitamin D (25-Hydroxy)
- Urine R/M (Urine Routine & Microscopy)
- Coronavirus Covid-19 Test (RT-PCR technique)
- LFT (Liver Function Test)
- Kidney Function Test
- TSH (Thyroid Stimulating Hormone) Ultrasensitive
- ESR (Erythrocyte Sedimentation Rate)
- Uric Acid
- Vitamin B12
- C- Reactive Protein Quantitative
- Urine Culture and Sensitivity
- Serum Electrolyte
- Serum Calcium
- Creatinine
- Diabetes Screening
- KFT with Electrolytes (Kidney Function Test with Electrolytes)
- Cholesterol - Total
- Hemoglobin
- Complete Haemogram
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