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Mygrain Tablet

Written By Dr. Anuj Saini, MMST, MBBS
Reviewed By Dr. Varun Gupta, MD Pharmacology, MBBS
Last updated on 12 Nov 2024 | 01:00 AM (IST)
Mygrain Tablet is a medicine used to prevent and treat migraine. It blocks the release of certain chemical messengers that cause pain and inflammation. It also blocks the signals in the brain that cause nausea and vomiting associated with migraine.
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Product introduction

Mygrain Tablet should be taken with food. This will prevent you from getting an upset stomach. The dose and duration will depend on what you are using it for and how well it helps your symptoms. Use it regularly and do not discontinue using it until the doctor tells you it is alright to stop.

It may cause side effects like sedation, orthostatic hypotension (sudden lowering of blood pressure on standing), drowsiness, urinary retention, and dryness in mouth in some patients. If you experience any of such side effects that do not go away or get worse, you should let your doctor know. Your doctor may be able to suggest ways of preventing or reducing the symptoms. In general, you should try to use the smallest amount necessary to control your symptoms.

Before using the medicine, you should tell your doctor if you have any other illnesses or disorders. It may also affect, or be affected by, some other medicines you are using so let your doctor know all the other medicines you are taking. It should be used with caution in patients who are alcoholic or have liver or kidney disease. Pregnant and breastfeeding women should consult their doctors first before using the medicine.

Uses of Mygrain Tablet

Side effects of Mygrain Tablet

Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them
Common side effects of Mygrain
  • Dryness in mouth
  • Constipation
  • Sedation
  • Orthostatic hypotension (sudden lowering of blood pressure on standing)
  • Drowsiness
  • Urinary retention
  • Increased heart rate
  • Muscle pain

How to use Mygrain Tablet

Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Mygrain Tablet is to be taken with food.

How Mygrain Tablet works

Mygrain Tablet is a combination of caffeine, ergotamine, paracetamol, and prochlorperazine. Ergotamine constricts blood vessels in the brain, reducing migraine pain caused by dilation. Caffeine enhances this effect by boosting ergotamine’s action. Paracetamol provides pain relief, while prochlorperazine helps control nausea and vomiting, which are common migraine symptoms. Together, these components work to alleviate headache pain and associated symptoms.

All substitutes for Mygrain Tablet

For information purposes only. Consult a doctor before taking any medicine.

Quick tips

  • Mygrain Tablet helps in the treatment and prevention of migraine headaches.
  • Do not take it to treat an acute attack of migraine.
  • Some tips that may help avoid a migraine attack:
    • Have your meals at the same time everyday
    • Avoid bright lights and extreme temperatures
    • Avoid loud music and noisy places
    • Avoid chocolates,  cheese, processed food, alcohol and smoking
    • Get sufficient sleep and avoid stress
  • It should be taken at night-time before going to bed.
  • It may cause sleepiness. Do not drive or do anything that requires mental focus until you know how Mygrain Tablet affects you.
  • Do not take it with any other medicine containing paracetamol (drugs for pain/fever or cough-and-cold) without asking your doctor first. 
  • Do not stop taking the medication suddenly as it can cause worsening of headaches.

Safety advice

Alcohol

Alcohol

UNSAFE
It is unsafe to consume alcohol with Mygrain Tablet.
Pregnancy

Pregnancy

UNSAFE
Mygrain Tablet is highly unsafe to use during pregnancy. Seek your doctor's advice as studies on pregnant women and animals have shown significant harmful effects to the developing baby.
Breast feeding

Breast feeding

CONSULT YOUR DOCTOR
Mygrain Tablet is probably unsafe to use during breastfeeding. Limited human data suggests that the drug may pass into the breastmilk and harm the baby.
Occasional short-term use of Mygrain Tablet for the treatment of nausea and vomiting poses little risk to the breastfed infant.
Driving

Driving

UNSAFE
Mygrain Tablet may decrease alertness, affect your vision or make you feel sleepy and dizzy. Do not drive if these symptoms occur.
Kidney

Kidney

CAUTION
Mygrain Tablet should be used with caution in patients with kidney disease. Dose adjustment of Mygrain Tablet may be needed. Please consult your doctor.
Liver

Liver

CAUTION
Mygrain Tablet should be used with caution in patients with liver disease. Dose adjustment of Mygrain Tablet may be needed. Please consult your doctor.
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Frequently asked questions

Mygrain Tablet is a combination of four medicines: Paracetamol, Ergotamine, Caffeine and Prochlorperazine. This medicine is used in the treatment of migraine symptoms like a headache, nausea and vomiting. Ergotamine prevents blood vessels in the head from expanding. Caffeine increases the absorption of ergotamine and also narrows the widened blood vessels. Paracetamol blocks the release of certain chemical messengers in the brain that causes pain. Prochlorperazine is an antiemetic which prevents vomiting by blocking signals to the part of your brain that cause nausea/vomiting.
Certain physical or environmental factors, such as foods, hormonal changes, weather and stress can lead to or “trigger” a migraine. However, it is important to remember that triggers can be different for everyone. That is why, to help prevent migraine attacks, you need to figure out which triggers affect you and which ones do not. Keeping a headache diary is an effective way to track triggers, and it will help you talk to your healthcare professional about your condition.
Mygrain Tablet is usually used for prevention and treatment of migraine attack. Mygrain Tablet should be continued as advised by the doctor.
Yes, the use of Mygrain Tablet can cause constipation. Lifestyle changes like eating a good amount of high-fiber foods such as fresh fruits, vegetables and cereals, drinking plenty of water or other fluids and regular exercise can help relieve constipation.
Yes, the use of Mygrain Tablet can cause dry mouth. If you experience dry mouth, drink plenty of water. Take regular sips during the day and keep some water by your bed at night. You may use lip balm if your lips are also dry. Try to avoid foods that are acidic (like lemons), spicy and salty.
Yes, Mygrain Tablet does expire. Please check the expiry date written on the pack of this medicine. Do not use Mygrain Tablet after the expiry date.
Mygrain Tablet is a combination of four medicines: Paracetamol, Ergotamine, Caffeine and Prochlorperazine. This medicine is used in the treatment of migraine symptoms like a headache, nausea and vomiting. Ergotamine prevents blood vessels in the head from expanding. Caffeine increases the absorption of ergotamine and also narrows the widened blood vessels. Paracetamol blocks the release of certain chemical messengers in the brain that causes pain. Prochlorperazine is an antiemetic which prevents vomiting by blocking signals to the part of your brain that cause nausea/vomiting.
A migraine is characterized by severe throbbing pain on one side of the head. The pain is usually pulsating in nature and is accompanied by nausea, vomiting, and sensitivity to light, sound and smell. The symptoms and severity vary from person to person.
Certain physical or environmental factors, such as foods, hormonal changes, weather and stress can lead to or “trigger” a migraine. However, it is important to remember that triggers can be different for everyone. That is why, to help prevent migraine attacks, you need to figure out which triggers affect you and which ones do not. Keeping a headache diary is an effective way to track triggers, and it will help you talk to your healthcare professional about your condition.
Mygrain Tablet is usually used for prevention and treatment of migraine attack. Mygrain Tablet should be continued as advised by the doctor.
Yes, the use of Mygrain Tablet can cause constipation. Lifestyle changes like eating a good amount of high-fiber foods such as fresh fruits, vegetables and cereals, drinking plenty of water or other fluids and regular exercise can help relieve constipation.
Yes, the use of Mygrain Tablet can cause dry mouth. If you experience dry mouth, drink plenty of water. Take regular sips during the day and keep some water by your bed at night. You may use lip balm if your lips are also dry. Try to avoid foods that are acidic (like lemons), spicy and salty.
Yes, Mygrain Tablet does expire. Please check the expiry date written on the pack of this medicine. Do not use Mygrain Tablet after the expiry date.

Fact Box

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No

Therapeutic Class

NEURO CNS
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100% genuine products
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Patient concerns

My father have migraine,what is the systems of mygrain

Dr. Tapas Kumbhkar
Dr. Tapas Kumbhkar
Internal Medicine
Consult nearby doctor who will examine you

I am facing issue of headache from last 3-4 years.i have consulted allopathy and they have given me sibelum 10 for migrane and asked to take metopar(paracetamol) when ever pain is too much.i am nit taking sibelum now but i am taking metopar when ever required.so i want a homeopathy consultatation if it can be cured by homeopathy or the level of headache can be lowered. Currently i face headache once in a week and i had to take metopar. Kindly suggest. My weight 80 kg And i am taking some neuro medicines ( stalopam 10, amitone 10) I also have cholesterol and taking (atorec 20)

Dr. Faran Siddiqui
Dr. Faran Siddiqui
Homeopathy
Migraine and headache are two different things migraine is primarily headache of one side in symmetrically
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Tata 1mg's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover everything about particular health conditions, lab tests, medicines, all possible side effects, drug interactions, warnings, alerts, etc. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.

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Country of origin: India
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