Nacphin Injection
Written By Dr. Swati Mishra, BDS
Reviewed By Dr. Ashish Ranjan, MD (Pharmacology), MBBS
Last updated on 12 Nov 2024 | 01:10 AM (IST)
Nacphin Injection is a pain-relieving medicine. It is used to treat moderate to severe pain. It is also used as a premedication before surgery. This medicine is generally used when alternative medicines are ineffective or inadequate.
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General Information
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Product introduction
Nacphin Injection is generally administered by a healthcare professional. You should not self-administer this medicine at home. The dose and duration will depend on what you are taking it for and how well it helps your symptoms.
The most common side effects of this medicine include injection site reactions (such as pain, redness, and swelling), headache, dizziness, sleepiness, nausea, vomiting, sweating, and constipation. If any of these side effects persist or get worse, you should let your doctor know. Your doctor may be able to suggest ways of preventing or reducing the symptoms.
Before using it, you should let your doctor know if you have a history of stomach ulcers, heart diseases, high blood pressure, and liver or kidney disease. Let your doctor also know about all the other medicines you are taking because they may affect, or be affected by, this medicine.
If you are pregnant or breastfeeding, it is important to ask the advice of your doctor before taking this medicine. Your doctor may also regularly monitor your kidney function, liver function, and levels of blood components if you are taking this medicine for long-term treatment.
The most common side effects of this medicine include injection site reactions (such as pain, redness, and swelling), headache, dizziness, sleepiness, nausea, vomiting, sweating, and constipation. If any of these side effects persist or get worse, you should let your doctor know. Your doctor may be able to suggest ways of preventing or reducing the symptoms.
Before using it, you should let your doctor know if you have a history of stomach ulcers, heart diseases, high blood pressure, and liver or kidney disease. Let your doctor also know about all the other medicines you are taking because they may affect, or be affected by, this medicine.
If you are pregnant or breastfeeding, it is important to ask the advice of your doctor before taking this medicine. Your doctor may also regularly monitor your kidney function, liver function, and levels of blood components if you are taking this medicine for long-term treatment.
Uses of Nacphin Injection
- Moderate to severe pain
Benefits of Nacphin Injection
Moderate to severe pain
Nacphin Injection helps to relieve moderate to severe pain in conditions that affect joints and muscles. It works by blocking chemical messengers in the brain that tell us we have pain. It can help relieve pain in conditions like rheumatoid arthritis and osteoarthritis.
It is given as an injection by a doctor or nurse and should not be self-administered. The dose and duration will be decided by the doctor depending on the condition you are being treated for. This will help you to go about your daily activities more easily and have a better, more active, quality of life.
Nacphin Injection helps to relieve moderate to severe pain in conditions that affect joints and muscles. It works by blocking chemical messengers in the brain that tell us we have pain. It can help relieve pain in conditions like rheumatoid arthritis and osteoarthritis.
It is given as an injection by a doctor or nurse and should not be self-administered. The dose and duration will be decided by the doctor depending on the condition you are being treated for. This will help you to go about your daily activities more easily and have a better, more active, quality of life.
Side effects of Nacphin Injection
Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them
Common side effects of Nacphin
- Injection site reactions (pain, swelling, redness)
- Headache
- Dizziness
- Sleepiness
- Nausea
- Vomiting
- Sweating
- Constipation
How to use Nacphin Injection
Your doctor or nurse will give you this medicine. Kindly do not self administer.
How Nacphin Injection works
Nacphin Injection is an opioid analgesic (pain reliever) which works by blocking transmission of pain signals to the brain to lower pain perception.
Quick tips
- Use Nacphin Injection as instructed by your doctor. Never take in greater amounts or more often than prescribed.
- It causes sleepiness or drowsiness. If this happens to you, do not drive or use machinery.
- Avoid consuming alcohol when taking the Nacphin Injection, as it may cause excessive sleepiness or drowsiness.
- Inform your doctor if you have ever been diagnosed with kidney or liver problems.
- Store opioid pain relievers in a safe place and out of reach of others.
Safety advice

Alcohol
UNSAFE
It is unsafe to consume alcohol with Nacphin Injection.

Pregnancy
SAFE IF PRESCRIBED
Nacphin Injection is generally considered safe to use during pregnancy. Animal studies have shown low or no adverse effects to the developing baby; however, there are limited human studies.

Breast feeding
SAFE IF PRESCRIBED
Nacphin Injection is probably safe to use during breastfeeding. Limited human data suggests that the drug does not represent any significant risk to the baby.

Driving
UNSAFE
Nacphin Injection may decrease alertness, affect your vision or make you feel sleepy and dizzy. Do not drive if these symptoms occur.

Kidney
CAUTION
Nacphin Injection should be used with caution in patients with kidney disease. Dose adjustment of Nacphin Injection may be needed. Please consult your doctor.

Liver
CAUTION
Nacphin Injection should be used with caution in patients with liver disease. Dose adjustment of Nacphin Injection may be needed. Please consult your doctor.

Frequently asked questions
Nacphin Injection may cause drowsiness and dizziness, especially in the beginning of the treatment. Do not drive or work with tools or machinery if your alertness is affected. It is not advisable to drink alcohol during treatment with this medicine as it might increase sleepiness.
Fact Box
Chemical Class
Morphinan Derivatives
Habit Forming
No
Therapeutic Class
PAIN ANALGESICS
Action Class
Opioids
References
- Yaksh TL, WallaceIn MS. Opioids, Analgesia, and Pain Management. In: Brunton LL, Chabner BA, Knollmann BC, editors. Goodman & Gilman’s: The Pharmacological Basis of Therapeutics. 12th ed. New York, New York: McGraw-Hill Medical; 2011. p. 509.
- Briggs GG, Freeman RK, editors. A Reference Guide to Fetal and Neonatal Risk: Drugs in Pregnancy and Lactation. 10th ed. Philadelphia, PA: Wolters Kluwer Health; 2015. pp. 950-51.
- Drugs.com. Nalbuphine. [Accessed 02 Apr. 2019] (online) Available from:
- Central Drugs Standard Control Organisation (CDSCO). [Accessed 02 Apr. 2019] (online) Available from:


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Marketer details
Name: Neon Laboratories Ltd
Address: 140, Damji Samji Industrial Complex, Mahakali Caves Rd., Andheri(East), Mumbai-93.
Address: 140, Damji Samji Industrial Complex, Mahakali Caves Rd., Andheri(East), Mumbai-93.
Vendor Details
Country of origin: India
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