Neotagmin Injection

Last updated on 12 Nov 2024 | 01:01 AM (IST)

Neotagmin Injection is a prescription medicine used in the treatment of myasthenia gravis (a disease-causing muscle weakness and tiredness), paralytic ileus (paralysis of intestinal muscles), postoperative urinary retention, and for reversal of effect of skeletal muscle relaxants after surgery.

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1/2

5 ml Injection

General Information

Contains

Neostigmine (NA)

Marketer

Themis Medicare Ltd

Storage

Store below 30°C

The content is shown in English

Product introduction

Neotagmin Injection works by reducing and improving muscle weakness. It is given as an injection under the supervision of a healthcare professional. Do not skip any doses and finish the full course of treatment and never stop this suddenly without talking to your doctor. However, before taking this medicine it is better to inform your doctor if you are suffering from any kidney disease, Parkinson's disease, asthma, or stomach disorders.

The most common side effects of this medicine are slow heart rate, nausea, and
vomiting. If you any other symptoms which you think are caused by the medicine, you should let your doctor know. They may be able to suggest ways to reduce or prevent the side effects. Pregnant and breastfeeding women should consult the doctor before taking this medicine.

Uses of Neotagmin Injection

Treatment of Myasthenia gravis
Treatment of Paralytic ileus
Treatment of Post-operative urinary retention
Reversal of effect of skeletal muscle relaxant after surgery

Benefits of Neotagmin Injection

Treatment of Myasthenia gravis
Myasthenia gravis is a neuromuscular disorder that leads to weakness of muscles that are under our control, such as those of the eyes, face, and swallowing. It can result in double vision, drooping eyelids, trouble talking, and trouble walking. It happens due to impaired coordination between muscles and nerves. Neotagmin Injection makes this coordination between nerves and muscles better and relieves the symptoms. As a result, your muscle strength is improved and you are able to lead a better life.

Treatment of Paralytic ileus
Paralytic ileus is the obstruction of the intestines due to improper functioning of the nerves and muscles in the intestine that impairs digestive movement. Neotagmin Injection induces contractions in the intestinal muscles and improves their function. As a result, there is better movement of food and this treats the obstruction. Take it as advised by the doctor and follow your doctor’s instructions carefully.

Treatment of Post-operative urinary retention
After an operation, there may be problems in emptying the bladder. This may be due to disturbed coordination of nerves and muscles of the bladder. Neotagmin Injection helps to improve this problem and treats postoperative urinary retention effectively.

Reversal of effect of skeletal muscle relaxant after surgery
Skeletal muscle relaxants are given to induce anesthesia and to carry out surgical or certain diagnostic procedures. This blocks the conduction of signals between nerves and muscles. After the surgery, Neotagmin Injection is given to reverse this effect and cause muscle contraction again to restore normal function.

Side effects of Neotagmin Injection

Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them

Common side effects of Neotagmin

Nausea
Vomiting
Slow heart rate

How to use Neotagmin Injection

Your doctor or nurse will give you this medicine. Kindly do not self administer.

How Neotagmin Injection works

Neotagmin Injection is a reversible cholinesterase inhibitor. It increases the level of acetylcholine, a chemical messenger in the brain, by suppressing acetylcholinesterase (enzyme). This acetylcholine further triggers muscle contracting receptors which helps in muscle contraction.

All substitutes for Neotagmin Injection

For information purposes only. Consult a doctor before taking any medicine.

Neotroy Injection

by Troikaa Pharmaceuticals Ltd

₹9.5/injection

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Quick tips

It is given into veins, muscles or under the skin by a healthcare professional.
Do not drink alcohol while taking this medicine as it may worsen the side effects.
Inform your doctor if you have an existing kidney problem, parkinson's disease, asthma, or stomach disorders.

Safety advice

Alcohol

UNSAFE

Neotagmin Injection may cause excessive drowsiness with alcohol.

Pregnancy

CONSULT YOUR DOCTOR

Neotagmin Injection may be unsafe to use during pregnancy. Although there are limited studies in humans, animal studies have shown harmful effects on the developing baby. Your doctor will weigh the benefits and any potential risks before prescribing it to you. Please consult your doctor.

Breast feeding

SAFE IF PRESCRIBED

Neotagmin Injection is probably safe to use during breastfeeding. Limited human data suggests that the drug does not represent any significant risk to the baby.

Driving

CONSULT YOUR DOCTOR

It is not known whether Neotagmin Injection alters the ability to drive. Do not drive if you experience any symptoms that affect your ability to concentrate and react.

Kidney

CAUTION

Neotagmin Injection should be used with caution in patients with kidney disease. Dose adjustment of Neotagmin Injection may be needed. Please consult your doctor.
Regular monitoring of kidney function test and some blood tests may advised while you are taking this medicine.

Liver

SAFE IF PRESCRIBED

Neotagmin Injection is probably safe to use in patients with liver disease. Limited data available suggests that dose adjustment of Neotagmin Injection may not be needed in these patients. Please consult your doctor.

Frequently asked questions

Does Neotagmin Injection treat myasthenia gravis? How long do I need to take it?

Neotagmin Injection relieves the symptoms of myasthenia gravis but does not cure it. It does so by reducing and improving muscle weakness. The length of time for which you need to take Neotagmin Injection will depend on your condition. Do not stop taking Neotagmin Injection until and unless advised by your doctor, even if you start feeling better.

How long does Neotagmin Injection take to start working?

Neotagmin Injection takes about 5 to 15 minutes to start working and remains effective for 2-4 hours.

Is Neotagmin Injection a steroid?

No, Neotagmin Injection is not a steroid. It belongs to cholinesterase inhibitor group of medicines. Neotagmin Injection work by preventing the breakdown of a chemical called acetylcholine.

Does it cause weight gain?

No, Neotagmin Injection does not cause weight gain. Your weight gain may be due to inactivity related to muscle weakness in myasthenia gravis.

Is Neotagmin Injection safe to use?

Yes, Neotagmin Injection is safe if used in the dose and duration prescribed by the doctor.

I felt better when I started taking Neotagmin Injection but I have noticed recently that I get tired easily and quickly. Will increasing the dose help me?

If your symptoms have started reappearing, then it could be due to increased severity of myasthenia gravis or excess dose of Neotagmin Injection. Both the conditions have similar effects, so it becomes very difficult to differentiate between the two. Do not increase the dose on your own and consult your doctor immediately.

Can I take Neotagmin Injection for constipation?

No, Neotagmin Injection should not be taken for any type of constipation. However, its use is limited to cases of constipation caused by paralysis of intestine and strictly on prescription by the doctor.

What should I do if I accidentally take more than the dose required?

You should seek immediate medical help in case of overdose of Neotagmin Injection.Excess of Neotagmin Injection may cause stomach pain, nausea, vomiting, diarrhea, blurred vision, difficulty in breathing, and excessive sweating, salivation, and weakness. It can even lead to paralysis.

Does Neotagmin Injection have any abuse potential?

No, there is no evidence of Neotagmin Injection having any abuse potential.

Who should not take Neotagmin Injection?

Neotagmin Injection should not be taken by patients who are allergic to it. Patients who are constipated or cannot urinate should avoid its use, unless advised by the doctor. This is because Neotagmin Injection is only used for certain types of urination problems and constipation (e.g. caused by paralysis of intestine).

Fact Box

Chemical Class

Phenoxy Compounds

Habit Forming

Therapeutic Class

NEURO CNS

Action Class

Cholinesterase inhibitors- carbamates

Related lab tests

Acetyl Choline Receptor Antibody

References

Briggs GG, Freeman RK, editors. A Reference Guide to Fetal and Neonatal Risk: Drugs in Pregnancy and Lactation. 10th ed. Philadelphia, PA: Wolters Kluwer Health; 2015. p. 969.
Drugs.com. Neostigmine Pregnancy and Breastfeeding Warnings. [Accessed 25 Mar. 2019] (online) Available from:
Drugs and Lactation Database (LactMed) [Internet]. Bethesda (MD): National Library of Medicine (US); 2006. Neostigmine. [Updated 2018 Oct 31]. [Accessed 20 Feb. 2020] (online) Available from:
Neostigmine. Gloucester Business Park, Gloucester: Hameln Pharmaceuticals Ltd.; 2001 [revised 12 Jan. 2018]. [Accessed 25 Mar. 2019] (online) Available from:
Neostigmine Methylsulfate Injection [FDA Label]. Chesterfield, MO: Éclat Pharmaceuticals; 2013. [Accessed 24 Sept. 2020]. (online) Available from:

Patient concerns

Drooping of eyelids. What is the cause of it? What is the remedy?

Dr. Vishal Maniar

Ophthalmology

At ur age u need detailed eye checkup and neurologist referenceTo rule out myasthenia gravis, ocular palsy Bells palsy,diabetes,trauma

Right medicine for myasthenia gravis

Dr. Vikas Sharma

Neurology

many ; cant advise online as they are strong medicine

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Tata 1mg's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover everything about particular health conditions, lab tests, medicines, all possible side effects, drug interactions, warnings, alerts, etc. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.

Marketer details

Name: Themis Medicare Ltd
Address: 11/12, Udyog Nagar, S. V. Road, Goregaon (W), Mumbai- 400104.

Vendor Details

Country of origin: India
A licensed vendor partner from your nearest location will deliver Neotagmin Injection. Once the pharmacy accepts your order, the details of the pharmacy will be shared with you. Acceptance of your order is based on the validity of your doctor's ℞ and the availability of this medicine.

In case of any issues, contact us

Email ID: [email protected]
Phone Number: 0124-4166666
Address: 5th Floor Tower - B of the Presidency Building, 46/4 Mehrauli Gurgaon Road, Sector 14, Gurugram, Haryana-122001, India

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In accordance with the law

Most medicines cannot be sold without a valid prescription, as per the Drugs and Cosmetics Act, 1940 and Rules, 1945