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Nexvir Z Tablet

Written By Dr. Love Sharma, PhD (Pharmacology), PGDPRA
Reviewed By Dr. Varun Gupta, MD Pharmacology, MBBS
Last updated on 11 Nov 2024 | 01:07 AM (IST)
Nexvir Z Tablet is a combination of antiretrovirals medicines. It is prescribed to treat HIV (human immunodeficiency virus) infection. It boosts up the immunity to fight against HIV to manage or treat AIDS (acquired immunodeficiency syndrome).
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General Information

Contains

Lamivudine (150mg)+ Zidovudine (300mg)+ Nevirapine (200mg)

Marketer

Nexus India

Storage

Store below 30°C
The content is shown in English
Nexvir Z Tablet image

Product introduction

Nexvir Z Tablet restricts the growth of HIV in the body and reduces the risk of getting HIV-related complications to improve the lifespan of an individual. The medicine can be taken with or without food. Taking these medicines regularly at the same time increases their effectiveness. A dose of this medicine should not be missed as it can affect your recovery. It is important to complete the full course of the treatment until your doctor advises you to stop it. Sudden discontinuation of the treatment may affect the potency of the medicine.

The most common side effects of this medicine are headaches, nasal congestion, diarrhea, nausea, weakness and tiredness, cough, and rash. These side effects are generally temporary, but if they persist or become serious inform your doctor. This medicine can also make you feel lazy or weak, so it is advised to avoid driving. Drinking plenty of fluid can help you to cope up with the side effects, so stay hydrated.

Before starting with the treatment, you should consult your doctor if you are pregnant or breastfeeding, or have any health condition. Your doctor may suggest regular blood tests to check your blood counts, kidney and liver functions, and other health conditions. If you are HIV positive, you should not breastfeed or share personal belongings like razors or toothbrushes. Consult your doctor to know about safe sex methods in order to prevent transmission of HIV during intercourse.

Uses of Nexvir Z Tablet

Benefits of Nexvir Z Tablet

HIV infection
Nexvir Z Tablet prevents the HIV virus from multiplying in your body. It helps control the infection and makes your immune system work better. This lowers your chances of getting complications such as new infections and improves your quality of life.

It is not a cure of HIV or AIDS and should not be used to prevent HIV after accidental exposure to a risk. It is important that you take this medicine as prescribed, following the dosage recommended by your doctor. Taking all doses in the right amount at the right times greatly increases the effectiveness of your combination of medicines and reduces the chances of your HIV infection becoming resistant to antiretroviral medicines. However, taking this medicine will not prevent you from passing HIV to other people.

Side effects of Nexvir Z Tablet

Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them
Common side effects of Nexvir Z
  • Headache
  • Insomnia (difficulty in sleeping)
  • Rash
  • Decreased white blood cell count (neutrophils)
  • Fever
  • Hair loss
  • Joint pain
  • Muscle disorders
  • Fatigue
  • General discomfort
  • Cough

How to use Nexvir Z Tablet

Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Nexvir Z Tablet may be taken with or without food, but it is better to take it at a fixed time.

How Nexvir Z Tablet works

Nexvir Z Tablet is a combination of three antiviral medicines: Lamivudine, Zidovudine and Nevirapine. They work by preventing HIV (virus) from multiplying, thereby reducing the amount of virus in your body. They also increase the CD4 cell (white blood cells that protect against infection) count in your blood.

Quick tips

  • Nexvir Z Tablet is a combination of three medicines which slows down or stops the progression of HIV infections.
  • Take it on an empty stomach, preferably at bedtime, to reduce side effects.
  • Skipping doses increases the risk of treatment failure. Make sure that you take all your doses at the correct time.
  • Nexvir Z Tablet may cause dizziness or sleepiness. Don't drive or do anything requiring concentration until you know how it affects you.
  • Nexvir Z Tablet can cause birth defects. Use effective contraception while taking Nexvir Z Tablet and 12 weeks after stopping it.
  • It may cause weakening of your bones. Exercise regularly and take calcium and vitamin D supplements as suggested by your doctor.
  • Your doctor may monitor your kidney and liver functions regularly. Inform your doctor if you develop symptoms such as abdominal pain, loss of appetite, darkened urine or yellowing of the eyes or skin.
  • Do not stop taking Nexvir Z Tablet without your doctor’s advice.

Safety advice

Alcohol

Alcohol

CAUTION
Caution is advised when consuming alcohol with Nexvir Z Tablet. Please consult your doctor.
Pregnancy

Pregnancy

CONSULT YOUR DOCTOR
Nexvir Z Tablet may be unsafe to use during pregnancy. Although there are limited studies in humans, animal studies have shown harmful effects on the developing baby. Your doctor will weigh the benefits and any potential risks before prescribing it to you. Please consult your doctor.
Breast feeding

Breast feeding

CONSULT YOUR DOCTOR
Nexvir Z Tablet is probably unsafe to use during breastfeeding. Limited human data suggests that the drug may pass into the breastmilk and harm the baby.
Driving

Driving

UNSAFE
Nexvir Z Tablet may cause side effects which could affect your ability to drive.
You may experience fatigue while taking Nexvir Z Tablet and this may affect your ability to drive.
Kidney

Kidney

CAUTION
Nexvir Z Tablet should be used with caution in patients with kidney disease. Dose adjustment of Nexvir Z Tablet may be needed. Please consult your doctor.
Liver

Liver

CAUTION
Nexvir Z Tablet should be used with caution in patients with liver disease. Dose adjustment of Nexvir Z Tablet may be needed. Please consult your doctor.
Use of Nexvir Z Tablet is not recommended in patients with moderate to severe liver disease. Regular monitoring of liver function tests is advised while you are taking this medicine.
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Fact Box

Habit Forming

No

Therapeutic Class

ANTI INFECTIVES

Related lab tests

HIV 1 & 2, Ab Western Blot

HIV 1 And 2 Antibody - Chromatography

HIV 1 And 2 Antibody - ELISA

References

  1. Lamivudine+Zidovudine+Nevirapine. Goa: Cipla Ltd.; 2009 [revised May 2011]. [19 Apr. 2019] (online) Available from:
  2. lamivudine+zidovudine. South Ruislip, Middlesex: Milpharm Limited; 2013 [revised 24 Jul. 2017]. [Accessed on 10 Apr. 2019] (online) Available from:
  3. Lamivudine. South Ruislip, Middlesex: Aurobindo Pharma - Milpharm Ltd.; 2012 [revised 24 Jun. 2018]. [Accessed 10 Apr. 2019] (online) Available from:
  4. Zidovudine. South Ruislip, Middlesex: Aurobindo Pharma - Milpharm Ltd.; 2008 [revised 10 Apr. 2018]. [Accessed 31 Mar. 2019] (online) Available from:
  5. Lamivudine, Nevirapine and Zidovudine [Drug Label]. Secunderabad, India: Matrix Laboratories Limited; 2008. [Accessed 16 Sep. 2024] (online) Available from:
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Patient concerns

i have unprotected sex with my friend. Can I take any drugs now to prevent any STD/HIV infection

Dr. Shyam Gupta
Dr. Shyam Gupta
Obstetrics and Gynaecology
Hello PATIENT to 1mg. There is some medicine for prophylactic but you need to see physician for prescription and better you check HIV status of both partner

hello, one of my frnd suffering with hiv infection from last 2yrs her cd4 is more than 470 and viral load is zero undetectable now she is using art medicines i have doubt that can we have to use art medicine in the whole life or can we stop it once we get viral load zero

Dr. Atula Gupta
Dr. Atula Gupta
Dermatology
You still need to be on ART even if the viral load is undetectable
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Tata 1mg's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover everything about particular health conditions, lab tests, medicines, all possible side effects, drug interactions, warnings, alerts, etc. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.

Marketer details

Name: Nexus India
Address: H-1 Building, Flat No 1, Phase III, Chintamani Nagar, Bibvewadi, Pune 411037.

Vendor Details

Country of origin: India

Lab tests offered by us

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Most medicines cannot be sold without a valid prescription, as per the Drugs and Cosmetics Act, 1940 and Rules, 1945
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