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Nupenzo 40mg Injection

Written By Dr. Swati Mishra, BDS
Reviewed By Dr. Ashish Ranjan, MD (Pharmacology), MBBS
Last updated on 12 Nov 2024 | 01:02 AM (IST)
Nupenzo 40mg Injection is used in the treatment of schizophrenia. It may also be used to treat depression and bipolar disorder. It alters the thoughts and elevates the mood, improving the person’s ability to think, feel and behave.
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General Information

Contains

Flupenthixol (40mg)

Marketer

Erikson Pharmaceuticals Pvt Ltd

Storage

Store below 30°C
The content is shown in English
Nupenzo 40mg Injection image

Product introduction

Nupenzo 40mg Injection is given as an injection under the supervision of a healthcare professional and should not be self-administered. Take it at the same time each day as this helps to maintain a consistent level of medicine in the body. Take this medicine in the dose and duration as advised by your doctor and if you have missed a dose, take it as soon as you remember it. Do not skip any doses and finish the full course of treatment even if you feel better. This medication mustn't be stopped suddenly without talking to your doctor as it may worsen your symptoms.

Some common side effects of this injection include dry mouth, abnormality of voluntary movements, urinary retention, constipation, and muscle rigidity. Initially, this medicine may cause a sudden drop in blood pressure when you change positions, rise slowly if you have been sitting or lying down. It may also cause dizziness and sleepiness, do not drive or do anything that requires mental focus until you know how this medicine affects you. This medicine can lead to weight gain, have a healthy balanced diet, and exercise regularly. You may also notice some injection site reactions such as pain, redness, or swelling. However, these are temporary and usually resolve on their own in some time. Please consult your doctor in case these do not subside or bother you.

Inform your doctor if you experience any abnormal movements, particularly of the face, lips, jaw, and tongue while using this injection. Your doctor may advise for regular monitoring of blood sugar and cholesterol levels. Additionally, avoid drinking alcohol while taking this medicine as it can make drowsiness worse. This medicine can also lead to weight gain, eat a healthy balanced diet, avoid snacking with high-calorie food, and exercise regularly.

Uses of Nupenzo Injection

Benefits of Nupenzo Injection

Schizophrenia
Schizophrenia is a mental disorder in which a person’s thinking ability, feelings and behavior become abnormal. Nupenzo 40mg Injection helps restore the chemical imbalances in the brain that are responsible for such changes. It improves thoughts, behavior and enhances the quality of life.
Depression
Nupenzo 40mg Injection helps in maintaining the balance of certain chemicals in the brain that affect mood and behavior. This improves your mood, relieves anxiety, tension, helps you sleep better and increases your energy levels. Nupenzo 40mg Injection prevents extreme changes in mood and helps you feel less agitated. You may experience fewer episodes of depression and low mood.
Bipolar disorder
Nupenzo 40mg Injection works to restore the normal balance of nerve activity in your brain. It can help prevent extreme changes in mood and help you feel less agitated. You may experience fewer episodes of low mood. It can take several weeks for this medicine to work and you may still feel low during this time. You should continue to eat well and keep fit to reduce symptoms of bipolar disorder.

Side effects of Nupenzo Injection

Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them
Common side effects of Nupenzo
  • Sleepiness
  • Orthostatic hypotension (sudden lowering of blood pressure on standing)
  • Dryness in mouth
  • Abnormality of voluntary movements
  • Weight gain
  • Increased prolactin level in blood
  • Urinary retention
  • Constipation
  • Muscle stiffness
  • Tremors
  • Injection site reactions (pain, swelling, redness)

How to use Nupenzo Injection

Your doctor or nurse will give you this medicine. Kindly do not self administer.

How Nupenzo Injection works

Nupenzo 40mg Injection is a typical antipsychotic. It works by blocking the action of dopamine, a chemical messenger in the brain that affects thoughts and mood.

Quick tips

  • You have been prescribed Nupenzo 40mg Injection for the treatment of schizophrenia.
  • It is administered into the muscle of the buttock or thigh by your doctor or healthcare professional.
  • Use caution while driving or doing anything that requires concentration as Nupenzo 40mg Injection can cause dizziness and sleepiness.
  • Avoid drinking alcohol while taking this medicine as it can make drowsiness worse.
  • Inform your doctor if you experience any abnormal movements, particularly of the face, lips, jaw and tongue, while taking this medicine.
  • It may increase your weight, blood sugar and cholesterol. Eat healthy, exercise regularly and monitor your blood levels regularly.
  • Don't stop taking Nupenzo 40mg Injection without talking  to your doctor first as it may cause worsening of symptoms.

Safety advice

Alcohol

Alcohol

UNSAFE
It is unsafe to consume alcohol with Nupenzo 40mg Injection.
Pregnancy

Pregnancy

CONSULT YOUR DOCTOR
Nupenzo 40mg Injection may be unsafe to use during pregnancy. Although there are limited studies in humans, animal studies have shown harmful effects on the developing baby. Your doctor will weigh the benefits and any potential risks before prescribing it to you. Please consult your doctor.
Breast feeding

Breast feeding

CONSULT YOUR DOCTOR
Nupenzo 40mg Injection is probably unsafe to use during breastfeeding. Limited human data suggests that the drug may pass into the breastmilk and harm the baby.
Driving

Driving

UNSAFE
Nupenzo 40mg Injection may decrease alertness, affect your vision or make you feel sleepy and dizzy. Do not drive if these symptoms occur.
Kidney

Kidney

CONSULT YOUR DOCTOR
There is limited information available on the use of Nupenzo 40mg Injection in patients with kidney disease. Please consult your doctor.
However, there have been reports of some side effects in patients with severe kidney disease.
Liver

Liver

CAUTION
Nupenzo 40mg Injection should be used with caution in patients with liver disease. Dose adjustment of Nupenzo 40mg Injection may be needed. Please consult your doctor.
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Frequently asked questions

Nupenzo 40mg Injection belongs to a class of medication called as typical antipsychotic. It acts by increasing the amounts of chemical (serotonin), in the brain. Nupenzo 40mg Injection decanoate is a long-acting preparation of Nupenzo 40mg Injection for injection into the muscles, which may be given at a frequency ranging from once in a week to once in 4 weeks
Nupenzo 40mg Injection is used in the treatment of schizophrenia and other psychoses which are disorders where individuals are unable to distinguish between what is real and unreal, think clearly, manage emotions, relate to others, and function normally
Nupenzo 40mg Injection in combination with melitracen is banned in india due to safety concern
Nupenzo 40mg Injection belongs to a class of medication called as typical antipsychotic. It acts by normalizing the levels of certain chemicals in the brain in specific brain pathways that are responsible for causing symptoms of the disease.

Fact Box

Chemical Class

Thioxanthene derivative

Habit Forming

No

Therapeutic Class

NEURO CNS

Action Class

Typical Antipsychotics

References

  1. Stahl SM, editor. Flupenthixol. In: Stahl's Essential Pschopharmacology: Prescriber's Guide. 5th ed. New York, New York: Cambridge University Press; 2014. pp. 253-57.
  2. Drugs and Lactation Database (LactMed) [Internet]. Bethesda (MD): National Library of Medicine (US); 2006. Flupenthixol. [Updated 2018 Dec 3]. [Accessed 20 Feb. 2020] (online) Available from:
  3. Central Drugs Standard Control Organisation (CDSCO). [Accessed 25 Mar. 2019] (online) Available from:
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Patient concerns

Treatment about bipolar disorder

Dr. Ravi Shankar M.
Dr. Ravi Shankar M.
Ayurveda
Tab. Manasa Mitra Vataki 1-0-1 and Kalyanaka Ghritam 10 gram twice a day with luke warm wtar after food and Sarswatharishta 15 ml twice a day with equal quantity of water for 2 months

Suffering from bipolar disorder

Dr. Jyoti Kapoor Madan
Dr. Jyoti Kapoor Madan
Psychiatry
Bipolar Affective Disorder is a chronic problem caused by Neuro chemical disturbance in brain. It is characterised by excessive mood swings leading to disruption in routine life. Treatment is with mood stabilizer medicines and antipsychotic medicines which may need to continue throughout life. Please see a psychiatrist for further guidance.
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Disclaimer

Tata 1mg's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover everything about particular health conditions, lab tests, medicines, all possible side effects, drug interactions, warnings, alerts, etc. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.

Marketer details

Name: Erikson Pharmaceuticals Pvt Ltd
Address: B-81,Nehru Nagar,Jaipur,Rajasthan,India

Vendor Details

Country of origin: India
A licensed vendor partner from your nearest location will deliver Nupenzo 40mg Injection. Once the pharmacy accepts your order, the details of the pharmacy will be shared with you. Acceptance of your order is based on the validity of your doctor's â„ž and the availability of this medicine.

In case of any issues, contact us

Email ID: [email protected]
Phone Number: 0124-4166666
Address: 5th Floor Tower - B of the Presidency Building, 46/4 Mehrauli Gurgaon Road, Sector 14, Gurugram, Haryana-122001, India

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