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Onglyza 5mg Tablet

Written By Dr. Betina Chandolia, MDS, BDS
Reviewed By Dr. Lalit Kanodia, MBA, MD Pharmacology
Last updated on 12 Nov 2024 | 01:08 AM (IST)
Onglyza 5mg Tablet is a medicine used to treat type 2 diabetes mellitus. It is used together with a healthy diet and regular exercise to control blood sugar levels. This helps to prevent serious complications of diabetes like kidney damage and blindness.
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General Information

Contains

Saxagliptin (5mg)

Marketer

AstraZeneca

Storage

Store below 30°C
The content is shown in English
Onglyza 5mg Tablet image
Onglyza 5mg Tablet image
Onglyza 5mg Tablet image
Onglyza 5mg Tablet image

Product introduction

You should take it regularly, at the same time each day, to get the most benefit and you should not stop unless your doctor recommends it. It is controlling your blood sugar levels and helping to prevent serious complications in the future. It is important to stay on the diet and exercise program recommended by your doctor while taking this medicine. Your lifestyle plays a big part in controlling diabetes.

The most common side effect of taking this medicine is a headache. This is usually minor and improves with time. Low blood sugar level (hypoglycemia) is a possible side effect if you are also taking other diabetes medicines like insulin or sulphonylurea, so you need to know how to recognize and deal with it. It may also cause upper respiratory tract infections like sore throat, cough, and cold. Contact your doctor if the side effects worry you or if they do not go away.

Before taking this medicine, let your doctor know if you have ever had kidney disease, heart or pancreas problems, or if you drink a lot of alcohol. Pregnant or breastfeeding women should also consult their doctor before taking it. Some other medicines you are taking may interfere with it so make sure your doctor knows about all the other medicines you are using. Limit your alcohol intake while taking this medicine because it can increase your risk of developing low blood sugar levels. You may need regular tests such as kidney function and blood glucose levels to check that the medicine is working properly.

Uses of Onglyza Tablet

Side effects of Onglyza Tablet

Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them
Common side effects of Onglyza
  • Hypoglycaemia (low blood sugar level) in combination with insulin or sulphonylurea
  • Upper respiratory tract infection
  • Urinary tract infection
  • Headache
  • Peripheral edema

How to use Onglyza Tablet

Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Onglyza 5mg Tablet may be taken with or without food, but it is better to take it at a fixed time.

How Onglyza Tablet works

Onglyza 5mg Tablet is an antidiabetic medication. It works by increasing the release of insulin from the pancreas and decreasing the hormones that raise blood sugar levels. This reduces the fasting and postmeal sugar levels.

All substitutes for Onglyza 5mg Tablet

For information purposes only. Consult a doctor before taking any medicine.

Zaglivia 5mg Tablet

by Hauz Pharma Pvt Ltd
₹43/tablet
3% costlier
<h3 class=bodySemiBold>Zaglivia 5mg Tablet</h3>

Zaxaglit 5mg Tablet

by Chemo Healthcare Pvt Ltd
₹41.9/tablet
same price
<h3 class=bodySemiBold>Zaxaglit 5mg Tablet</h3>

Saglipol 5 Tablet

by Medipol Pharmaceuticals India Pvt Ltd
₹57.2/tablet
36% costlier
<h3 class=bodySemiBold>Saglipol 5 Tablet</h3>

Saxaquest 5mg Tablet

by Morepen Laboratories Ltd
₹19/tablet
55% cheaper
<h3 class=bodySemiBold>Saxaquest 5mg Tablet</h3>

Quick tips

  • Onglyza 5mg Tablet should be taken at the same time every day since this helps you remember to take it.
  • Be careful while driving or operating machinery until you know how Onglyza 5mg Tablet affects you.
  • It may cause hypoglycemia (low blood sugar level) when used with other antidiabetic medicines, alcohol or if you delay or miss a meal.
  • Always carry some sugary food or fruit juice with you in case you experience hypoglycemia symptoms such as cold sweats, cool pale skin, tremor and anxiety.
  • Inform your doctor if you notice joint pains or develop symptoms such as stomach pain, nausea and/or vomiting.

Safety advice

Alcohol

Alcohol

UNSAFE
It is unsafe to consume alcohol with Onglyza 5mg Tablet.
Pregnancy

Pregnancy

SAFE IF PRESCRIBED
Onglyza 5mg Tablet is generally considered safe to use during pregnancy. Animal studies have shown low or no adverse effects to the developing baby; however, there are limited human studies.
Breast feeding

Breast feeding

CONSULT YOUR DOCTOR
Onglyza 5mg Tablet is probably unsafe to use during breastfeeding. Limited human data suggests that the drug may pass into the breastmilk and harm the baby.
Driving

Driving

CAUTION
Your ability to drive may be affected if your blood sugar is too low or too high. Do not drive if these symptoms occur.
Kidney

Kidney

CAUTION
Onglyza 5mg Tablet should be used with caution in patients with kidney disease. Dose adjustment of Onglyza 5mg Tablet may be needed. Please consult your doctor.
Regular monitoring of kidney function tests is recommended for dose adjustment.
Liver

Liver

SAFE IF PRESCRIBED
Onglyza 5mg Tablet is safe to use in patients with liver disease. No dose adjustment of Onglyza 5mg Tablet is recommended.
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Frequently asked questions

No, Onglyza 5mg Tablet neither causes weight loss nor weight gain. It is weight neutral. However, weight gain can be seen when Onglyza 5mg Tablet is used with other antidiabetic medicines like thiazolidinediones, sulfonylureas or insulin.
Onglyza 5mg Tablet when taken with insulin can help in lowering the insulin dose and decrease the risk of hypoglycemia (low blood sugar levels). Consult your doctor as a dose adjustment of the two may be needed.
Yes, the use of Onglyza 5mg Tablet is contraindicated in some conditions like a history of allergy to Onglyza 5mg Tablet, any ingredients of this drug or to any other drug of the same class. Onglyza 5mg Tablet should also be avoided in patients with a history of pancreatitis.
Yes, it is beneficial to take Onglyza 5mg Tablet and glipizide. Both are antidiabetic drugs, however, they work in different ways. When taken together, they can help in better controlling of blood sugar levels.
Yes, Onglyza 5mg Tablet can be used alone or in combination with other diabetes medicines, along with proper diet and exercise.
Usually, Onglyza 5mg Tablet does not cause hypoglycemia when used alone in diabetes. However, it may cause low blood sugar when combined with other medicines like insulin and sulfonylureas.

Fact Box

Chemical Class

Alpha amino acid amides

Habit Forming

No

Therapeutic Class

ANTI DIABETIC

Action Class

Dipeptidyl Peptidase-4 (DPP-4) Inhibitors

Related lab tests

Glucose - Fasting Blood

Glucose - Postprandial Blood

Glycosylated Hemoglobin

References

  1. Powers AC, D’Alessio D. Endocrine Pancreas and Pharmacotherapy of Diabetes Mellitus and Hypoglycemia. In: Brunton LL, Chabner BA, Knollmann BC, editors. Goodman & Gilman’s: The Pharmacological Basis of Therapeutics. 12th ed. New York, New York: McGraw-Hill Medical; 2011. p. 1264.
  2. Briggs GG, Freeman RK, editors. A Reference Guide to Fetal and Neonatal Risk: Drugs in Pregnancy and Lactation. 10th ed. Philadelphia, PA: Wolters Kluwer Health; 2015. pp. 1248-49.
  3. Saxagliptin. Princeton, New Jersey: Bristol-Myers Squibb Company; 2009. [Accessed 12 Mar. 2019] (online) Available from:
  4. Saxagliptin. Macclesfield, Cheshire: AstraZeneca UK Limited; 2018. [Accessed 12 Mar. 2019] (online) Available from:
  5. Saxagliptin [Summary of Product Characteristics]. Södertälje, Sweden; AstraZeneca AB. [Accessed 09 Feb. 2022] (online) Available from:
  6. Saxagliptin [FDA Prescribing Information]. Wilmington, DE; AstraZeneca Pharmaceuticals LP; 2015. [Accessed 09 Feb. 2022] (online) Available from:
  7. Saxagliptin [EMC Label]. Luton, UK; AstraZeneca UK Limited; 2021. [Accessed 09 Feb. 2022] (online) Available from:
  8. Saxagliptin [Prescribing Informataion]. Princeton, NJ: Bristol-Myers Squibb Company; 2009. [Accessed 20 Feb. 2024] (online) Available from:
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User feedback

Once A Day
95%
Twice A Day
4%
Type 2 diabetes
100%
Excellent
100%

Patient concerns

Diabetes mellitus type 2 ,thirst

Dr. Sanjay Bhatt
Dr. Sanjay Bhatt
Physician
A person can control his or her sugar levels by doing regular exercise and walk or regular aerobic exercises at least 30 to 45 minutes per day.MEDICAL NUTRITIONAL THERAPY THAT IS TO MAINTAIN CALORIES INTAKE AS PER BMI .TAKE HELP OF DIABETIC EDUCATOR. VISIT YOUR DOCTOR AND FOLLOW ALL WHAT DOCTOR SUGGESTED.IN TIME ALL ROUTINE INVESTIGATIONS SHOULD BE DONE.you should not treat it as disease but a start of a healthy life.Uncontrolled sugar levels for long time leads to lower limb weakness which is neuropathy and which is followed by foot ulcers and other complications like kidney or heart problems .online prescription is not allowed without seeing pt.so contact doctor nearby for any change or dose adjustment or visit my clinic at gurgaon sector 52 RdCity snergy multi speciality clinic near SRS MARKET

I am taking dianorm M three times a day & onglyza 5mg once a day.average HbA1C 175 .my dose is right?

Dr. Sanjay Bhatt
Dr. Sanjay Bhatt
Physician
No. Discuss with your doctor
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Tata 1mg's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover everything about particular health conditions, lab tests, medicines, all possible side effects, drug interactions, warnings, alerts, etc. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.

Marketer details

Name: AstraZeneca
Address: Corporate & Registered Office, Block N1, 12th Floor, Manyata Embassy Business Park, Rachenahalli, Outer Ring Road, 560045, Bangalore

Vendor Details

Country of origin: India
A licensed vendor partner from your nearest location will deliver Onglyza 5mg Tablet. Once the pharmacy accepts your order, the details of the pharmacy will be shared with you. Acceptance of your order is based on the validity of your doctor's ℞ and the availability of this medicine.

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Phone Number: 0124-4166666
Address: 5th Floor Tower - B of the Presidency Building, 46/4 Mehrauli Gurgaon Road, Sector 14, Gurugram, Haryana-122001, India

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