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Oresugrel 5mg Tablet

Written By Dr. Anuj Saini, MMST, MBBS
Reviewed By Dr. Ashish Ranjan, MD (Pharmacology), MBBS
Last updated on 23 Jul 2024 | 08:36 PM (IST)
Oresugrel 5mg Tablet belongs to a group of medicines called antiplatelets or blood thinners. It helps prevent the formation of harmful blood clots and keeps the blood flowing smoothly through your body. This lowers the chances of another heart attack or stroke in people with heart disease.
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General Information

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Product introduction

Oresugrel 5mg Tablet is used to treat people with a recent heart attack or severe heart-related chest pain (unstable angina), who have undergone stenting of the heart. It helps to prevent serious heart-related problems like having another heart attack, stroke, or formation of blood clots in stents.

This medicine may be prescribed along with aspirin, another antiplatelet medicine. It may be taken with or without food and should be taken regularly at the same time each day. It is important to keep taking this medicine even if you feel well. If you stop taking this medicine, it may increase your chances of having another heart attack or stroke.

The most common side effect seen with this medicine is bleeding. This may be in the form of bruising, nose bleeds, blood in urine or stools (black-colored stools), or heavier periods than usual in women. If you cut or injure yourself, it may take longer than usual for the bleeding to stop. Such episodes of bleeding are usually mild and resolve on their own. However, you should consult your doctor straight away if the bleeding persists or worries you.

This medicine is not suitable for some people. Do not take it if you are bleeding from anywhere in the body such as a stomach ulcer or bleeding within the brain, or if you have severe liver problems. Before taking it, you should let your doctor know if you have ever had a problem with your blood not clotting properly or if you have recently had a serious injury or surgery. This medicine may need to be stopped temporarily before planned surgery or dental treatment.

Benefits of Oresugrel Tablet

Prevention of Heart attack
Oresugrel 5mg Tablet is an antiplatelet medicine, or blood thinner. It works by preventing cells called platelets from sticking together and helps to prevent your blood from clotting inside veins and arteries. This helps the blood flow freely around your body thereby preventing a heart attack or stroke (or deep vein thrombosis or pulmonary embolism). Take this medicine regularly and make appropriate lifestyle changes to achieve maximum benefits. It is often prescribed along with a low dose of aspirin which also helps to prevent blood from clotting.

Side effects of Oresugrel Tablet

Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them
Common side effects of Oresugrel
  • Bleeding

How to use Oresugrel Tablet

Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Oresugrel 5mg Tablet may be taken with or without food, but it is better to take it at a fixed time.

How Oresugrel Tablet works

Oresugrel 5mg Tablet is an antiplatelet medication. It works by preventing platelets from sticking together, thereby decreasing the formation of harmful blood clots. This lowers the chances of another heart attack or stroke.

Quick tips

  • For best results, take it at the same time every day.
  • Oresugrel 5mg Tablet increases your risk of bleeding. Be careful while shaving, using sharp objects, or cutting fingernails or toenails.
  • Do not discontinue using the medicine without consulting your doctor as this may increase your chances of having another heart attack or stroke.
  • If you are scheduled to undergo a surgery or dental treatment, you may be asked to stop taking Oresugrel 5mg Tablet temporarily.

Safety advice

Alcohol

Alcohol

SAFE
Consuming alcohol with Oresugrel 5mg Tablet does not cause any harmful side effects.
Pregnancy

Pregnancy

CONSULT YOUR DOCTOR
Information regarding the use of Oresugrel 5mg Tablet during pregnancy is not available. Please consult your doctor.
Breast feeding

Breast feeding

CONSULT YOUR DOCTOR
Information regarding the use of Oresugrel 5mg Tablet during breastfeeding is not available. Please consult your doctor.
Driving

Driving

SAFE
Oresugrel 5mg Tablet does not usually affect your ability to drive.
Kidney

Kidney

SAFE IF PRESCRIBED
Oresugrel 5mg Tablet is probably safe to use in patients with kidney disease. Limited data available suggests that dose adjustment of Oresugrel 5mg Tablet may not be needed in these patients. Please consult your doctor.
Liver

Liver

CAUTION
Oresugrel 5mg Tablet should be used with caution in patients with severe liver disease. Dose adjustment of Oresugrel 5mg Tablet may be needed. Please consult your doctor.
Limited information is available on the use of Oresugrel 5mg Tablet in these patients. No dose adjustment is recommended in patients with mild to moderate liver disease.

Frequently asked questions

Yes, Oresugrel 5mg Tablet is a type of blood thinner. It works by preventing platelets (type of blood cells) from sticking together and forming clots. This action of Oresugrel 5mg Tablet helps in preventing conditions like heart attack or stroke in people with heart disease, who have recently suffered a heart attack or severe heart-related chest pain (unstable angina).
It is not advised to take alcohol while taking Oresugrel 5mg Tablet, as alcohol may increase your chance of stomach bleeding. As a result, you may vomit blood (which may be bright red blood or black/dark brown like coffee grounds) or you may have bloody or black tarry stools. Discuss with your doctor if you are not sure.
Oresugrel 5mg Tablet is usually prescribed along with aspirin in to prevent serious or life-threatening problems associated with heart or blood vessels (like heart attack, stroke, clot formation in a stent). This combination of medicine is given to patients who have recently had a heart attack and underwent angioplasty (stent placement in blocked blood vessels of the heart)had a heart attack, stroke, or had angioplasty to remove the blockage in arteries which supply the heart. Please consult your doctor before taking any medicine if you are taking Oresugrel 5mg Tablet and follow the doctor’s instructions carefully to get maximum benefit.
Your doctor will decide whether you need to stop taking Oresugrel 5mg Tablet before any surgery or treatment or not. Usually, if a surgery or treatment is planned beforehand, the doctor may stop Oresugrel 5mg Tablet a few days (usually 7 days) before the surgery or treatment owing to the increased risk of bleeding during the procedure. You should not stop taking Oresugrel 5mg Tablet on your own without discussing it with your doctor.
Oresugrel 5mg Tablet may cause serious or life-threatening bleeding. Moreover, you may bruise easily and it may take longer than usual for bleeding to stop even if you have a minor injury such as a small cut while shaving. Get emergency medical help if you notice excessive or prolonged bleeding. You should inform your doctor if you notice black tarry stools or if there is blood in the urine. Be vigilant on any signs of stroke such as sudden numbness or weakness (one side or both sides of the body), difficulty walking, mental confusion, slurred speech, dizziness and any unexplained headache. Contact your doctor immediately if you develop any such signs of stroke as stroke is an uncommon side effect of Oresugrel 5mg Tablet and needs urgent medical attention as it can otherwise be fatal.
If you have missed a dose of Oresugrel 5mg Tablet, take it as soon as you remember it. However, if it is almost time for your next dose, take it in the regular schedule instead of taking the missed dose. Do not double the dose to make up for the missed one as this may increase the chances of developing side effects.
The exact duration of taking Oresugrel 5mg Tablet will be decided by your doctor after considering various factors like the illness you are being treated for, type of stent inserted, any episodes of bleeding experienced by you during treatment etc. Usually, it is prescribed for a minimum duration of 1 year. However, follow your doctor's advice precisely to get maximum benefit of Oresugrel 5mg Tablet. Discuss with your doctor before stopping the medication, as sudden discontinuation may increase the chances of clot formation in the stent, heart attack, and can even lead to death.
Avoid activities that may increase your chances of bleeding. Be extra careful while shaving or brushing your teeth to prevent bleeding. You should avoid taking painkillers, but if you need to take one like ibuprofen for joint pain, headache, backache etc, then consult your doctor first. This is because taking pain killers with Oresugrel 5mg Tablet may increase your chances of developing a stomach ulcer and bleeding. Refrain from taking excessive alcohol with Oresugrel 5mg Tablet as it can irritate your stomach and lead to a stomach ulcer as well.

Fact Box

Chemical Class

Piperazine derivative

Habit Forming

No

Therapeutic Class

BLOOD RELATED

Action Class

P2Y12 inhibitors (ADP receptor)

References

  1. Weitz JI. Blood Coagulation and Anticoagulant, Fibrinolytic, and Antiplatelet Drugs. In: Brunton LL, Chabner BA, Knollmann BC, editors. Goodman & Gilman’s: The Pharmacological Basis of Therapeutics. 12th ed. New York, New York: McGraw-Hill Medical; 2011. p. 870.
  2. Flipiox KA, White HD, Gersh BJ, et al. Antithrombotic Agents: Platelete Inhibitors, Acute Anticoagulants, Fibrinolytics, and Chronic Anticoagulants. In: Opie LH, Gersh BJ, editors. Drugs for the Heart. 8th ed. Philadelphia, Pennsylvania: Elsevier Saunders; 2013. pp. 350-51
  3. Briggs GG, Freeman RK, editors. A Reference Guide to Fetal and Neonatal Risk: Drugs in Pregnancy and Lactation. 10th ed. Philadelphia, PA: Wolters Kluwer Health; 2015. pp. 1142-43.
  4. Prasugrel. Indianapolis, Indiana: Eli Lilly and Company; 2009. [Accessed 25 Jan. 2019] (online) Available from:
  5. Drugs.com. Prasugrel Pregnancy and Breastfeeding Warnings. [Accessed 20 Mar. 2019] (online) Available from:
  6. Central Drugs Standard Control Organisation (CDSCO). [Accessed 19 Mar. 2019] (online) Available from:
  7. Prasugrel [Prescribing Information]. Durham, NC: Accord Healthcare, Inc.; 2022. [Accessed 05 Aug. 2023] (online) Available from:
  8. Sampat PJ, Wadhwa R. Prasugrel. [Updated 2023 Apr 10]. In: StatPearls [Internet]. Treasure Island (FL): StatPearls Publishing; 2023. [Accessed 25 Jul. 2023] (online) Available from:
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Patient concerns

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Disclaimer

Tata 1mg's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover everything about particular health conditions, lab tests, medicines, all possible side effects, drug interactions, warnings, alerts, etc. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.

Marketer details

Name: Druto Laboratories
Address: 1003 Kirti Shikhar Building, Janakpuri, Delhi - 110058, Distt Centre

Vendor Details

Country of origin: India
A licensed vendor partner from your nearest location will deliver Oresugrel 5mg Tablet. Once the pharmacy accepts your order, the details of the pharmacy will be shared with you. Acceptance of your order is based on the validity of your doctor's ℞ and the availability of this medicine.

In case of any issues, contact us

Email ID: [email protected]
Phone Number: 0124-4166666
Address: 5th Floor Tower - B of the Presidency Building, 46/4 Mehrauli Gurgaon Road, Sector 14, Gurugram, Haryana-122001, India
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