Pamiglan 500mg Injection

Written By Dr. Anuj Saini, MMST, MBBS

Reviewed By Dr. Lalit Kanodia, MBA, MD Pharmacology

Last updated on 29 Oct 2024 | 01:06 AM (IST)

Pamiglan 500mg Injection is used in the treatment of non-small cell lung cancer and malignant pleural mesothelioma.

Genuine

Authenticity Assured

Prescription

required

Cold stored

Stored between 2-8°C

MRP ₹156451.3

General Information

Contains

Pemetrexed (500mg)

Marketer

Gland Pharma Limited

Storage

Store in a refrigerator (2 - 8°C). Do not freeze.

The content is shown in English

Product introduction

Pamiglan 500mg Injection is given as an injection by a qualified medical professional. Your doctor will decide what dose is necessary and how often you need to take it. This will depend on what you are being treated for and may change from time to time. You should take it exactly as your doctor has advised. Taking it in the wrong way or taking too much can cause very serious side effects. It may take several weeks or months for you to see or feel the benefits but do not stop taking it unless your doctor tells you to.

The most common side effects of this medicine include nausea, vomiting, loss of appetite, and hair loss. This medicine may reduce the number of blood cells (decrease red blood and white blood cells) in your blood, thereby, increasing the susceptibility to infections. Regular blood tests are required to check your blood cells along with heart, liver and blood uric acid levels.

Before taking it, tell your doctor if have heart disease, liver, or kidney problems or are taking any medicines to treat infections. Many other medicines can affect, or be affected by, this medicine so let your doctor know all medications you are using.This medicine is not recommended during pregnancy or while breastfeeding. Use of effective contraception by both males and females during treatment is important to avoid pregnancy.

Uses of Pamiglan Injection

Non-small cell lung cancer
Malignant pleural mesothelioma

Benefits of Pamiglan Injection

Non-small cell lung cancer
Non-small cell lung cancer is one of the major kinds of lung cancer and it affects both smokers as well as non-smokers. Pamiglan 500mg Injection helps treat non-small cell lung cancer and may be given alone or in combination with other medicines. It is a potent and very toxic medicine and you should discuss the risks and benefits with your doctor. You should avoid drinking alcohol while having this treatment and drink plenty of water to stay hydrated.

Malignant pleural mesothelioma
Malignant pleural mesothelioma is a form of cancer that develops in the lungs and the inner side of the ribs. It is a very aggressive form of lung cancer. Pamiglan 500mg Injection is used along with some other medicines to treat this cancer. It kills the cancer cells, and prevents the further multiplication of cancer cells. This restricts the spread of cancer to other unaffected areas. Follow your doctor’s instructions carefully and consult your doctor if you have any doubts.

Side effects of Pamiglan Injection

Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them

Common side effects of Pamiglan

Nausea
Vomiting
Sore throat
Loss of appetite
Stomatitis (Inflammation of the mouth)
Hair loss
Low blood platelets
Rash
Fatigue
Anemia (low number of red blood cells)
Diarrhea
Decreased white blood cell count (neutrophils)
Neuropathy

How to use Pamiglan Injection

Your doctor or nurse will give you this medicine. Kindly do not self administer.

How Pamiglan Injection works

Pamiglan 500mg Injection interferes with the growth of DNA and RNA of the cancer cells by substituting their building blocks. It prevents the cancer cells from growing and multiplying.

All substitutes for Pamiglan 500mg Injection

For information purposes only. Consult a doctor before taking any medicine.

Quick tips

Use a reliable contraceptive method to prevent pregnancy while you are taking this medicine.
Inform your doctor immediately if you notice any signs of infection such as fever, sore throat, rash or severe diarrhea.

Safety advice

Alcohol

SAFE

Consuming alcohol with Pamiglan 500mg Injection does not cause any harmful side effects.

Pregnancy

CONSULT YOUR DOCTOR

Pamiglan 500mg Injection is unsafe to use during pregnancy as there is definite evidence of risk to the developing baby. However, the doctor may rarely prescribe it in some life-threatening situations if the benefits are more than the potential risks. Please consult your doctor.

Breast feeding

CAUTION

Pamiglan 500mg Injection should be used with caution during breastfeeding. Breastfeeding should be held until the treatment of the mother is completed and the drug is eliminated from her body.

Driving

UNSAFE

Pamiglan 500mg Injection may cause side effects which could affect your ability to drive.
Pamiglan 500mg Injection may make you feel tired and this may affect your ability to drive.

Kidney

CAUTION

Pamiglan 500mg Injection should be used with caution in patients with kidney disease. Dose adjustment of Pamiglan 500mg Injection may be needed. Please consult your doctor.
Use of Pamiglan 500mg Injection is not recommended in patients with moderate to severe kidney disease.

Liver

SAFE IF PRESCRIBED

Pamiglan 500mg Injection is probably safe to use in patients with liver disease. Limited data available suggests that dose adjustment of Pamiglan 500mg Injection may not be needed in these patients. Please consult your doctor.

Frequently asked questions

Is Pamiglan 500mg Injection a vesicant?

No. Pamiglan 500mg Injection is not a vesicant.

Is Pamiglan 500mg Injection safe?

Pamiglan 500mg Injection is safe if used at prescribed doses for the prescribed duration as advised by your doctor.

Does Pamiglan 500mg Injection cause hair loss?

Yes. Pamiglan 500mg Injection is a prescription chemotherapy medication and hair loss is one of the possible side effects.

Fact Box

Chemical Class

Glutamic Aacid Derivatives

Habit Forming

Therapeutic Class

ANTI NEOPLASTICS

Action Class

Antimetabolites

References

Chu E, Sartorelli AC. Cancer Chemotherapy. In: Katzung BG, Masters SB, Trevor AJ, editors. Basic and Clinical Pharmacology. 11th ed. New Delhi, India: Tata McGraw Hill Education Private Limited; 2009. p. 946.
Briggs GG, Freeman RK, editors. A Reference Guide to Fetal and Neonatal Risk: Drugs in Pregnancy and Lactation. 10th ed. Philadelphia, PA: Wolters Kluwer Health; 2015. p. 1077.
Pemetrexed disodium. Basingstoke, Hampshire: Eli Lilly and Company Limited; 2004 [revised 10 Jan. 2019]. [Accessed 28 Jan. 2019] (online) Available from:
Pemetrexed. Indianapolis, Indiana: Lilly USA; 2004 [revised Sep. 2013]. [Accessed 26 Mar. 2019] (online) Available from:
Central Drugs Standard Control Organisation (CDSCO). [Accessed 26 Mar. 2019] (online) Available from:

Patient concerns

What is the purpose of Chemotherepy given at the time of radiotherapy in ca lung small cell carcinoma

Dr. Vijay Sharnangat

Medical Oncology and Hematology

This is given to enhance the therapeutic effect of radiation therapy which is curative for small cell lung cancer.

Good evening, my father is suffering from lung cancer naming malignant mesothelioma. The same type of cancer my grandmother have. They both died due to this cancer disease. I want to know that is this a heridatory type of cancer? Is there is any probability in future that I will suffer from this type of cancer. Actually is their any preventive type of measures that I can follow that will help me prevent in future from suffering from cancer. Is their any tests available to keep regular updates about the trace of the cancer,

Dr. Vijay Sharnangat

Medical Oncology and Hematology

Restrain from any addiction, have regular exercise, eat healthy food.It's not hereditary, please don't get afraid.

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Disclaimer

Tata 1mg's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover everything about particular health conditions, lab tests, medicines, all possible side effects, drug interactions, warnings, alerts, etc. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.

Marketer details

Name: Gland Pharma Limited
Address: Gland Pharma Limited, 6-3-865/1/2, Greenland Apartments, Ameerpet, Hyderabad - 500016, India

Vendor Details

Country of origin: India

Lab tests offered by us

Why we need a prescription?

Pamiglan 500mg Injection

General Information

Contains

Marketer

Storage

Product introduction

Uses of Pamiglan Injection

Benefits of Pamiglan Injection

Side effects of Pamiglan Injection

How to use Pamiglan Injection

How Pamiglan Injection works

All substitutes for Pamiglan 500mg Injection

Alimta 500mg Injection

Pemnat 500mg Injection

Pemetero 500 Injection

Pemexam 500mg Injection

Symyx 500mg Injection

Quick tips

Safety advice

Alcohol

Pregnancy

Breast feeding

Driving

Kidney

Liver

Frequently asked questions

Is Pamiglan 500mg Injection a vesicant?

Is Pamiglan 500mg Injection safe?

Does Pamiglan 500mg Injection cause hair loss?

Fact Box

Chemical Class

Habit Forming

Therapeutic Class

Action Class

References

Patient concerns

What is the purpose of Chemotherepy given at the time of radiotherapy in ca lung small cell carcinoma

Want to know more

Have issue with the content

Disclaimer

Marketer details

Vendor Details

Lab tests offered by us

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