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Peg-Joxorub Solution for Infusion

Written By Dr. Anuj Saini, MMST, MBBS
Reviewed By Dr. Varun Gupta, MD Pharmacology, MBBS
Last updated on 12 Nov 2024 | 01:05 AM (IST)
Peg-Joxorub Solution for Infusion is used in the treatment of some kinds of cancer. It is also used in the treatment of breast cancer, where there is an increased cardiac risk. It can be used on its own, or sometimes given together with certain other medicines as part of combination chemotherapy.
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1/2
25 ml Solution for Infusion
 
 
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General Information

Contains

Doxorubicin (Liposomal) (2mg/ml)

Marketer

Jodas Expoim

Storage

Store in a refrigerator (2 - 8°C). Do not freeze.
The content is shown in English
Peg-Joxorub Solution for Infusion image
Peg-Joxorub Solution for Infusion image

Product introduction

Peg-Joxorub Solution for Infusion can be used in both adults and children. It is given as injection into vein with extreme caution by a qualified medical professional. Your doctor will decide what dose is necessary and how often you need to take it. This will depend on what you are being treated for and may change from time to time. You should take it exactly as your doctor has advised. Taking it in the wrong way or taking too much can cause very serious side effects. It may take several weeks or months for you to see or feel the benefits but do not stop taking it unless your doctor tells you to. It makes contraceptive pills less effective, so it advised to use reliable contraception during and after 6 months of the treatment.

The most common side effects of this medicine include nausea, vomiting, rash, weakness, low blood platelets. If they do not go away or get worse, tell your doctor. There may be ways of preventing or reducing these effects. It is very strong medicine and some people may develop serious side effects while taking it. This medicine may lead to problems with your blood, liver or heart. Your doctor will advise you regular blood tests to check for these.

Before taking this medicine, let your doctor know if you have liver disease. Your doctor should also know about all other medicines you are taking as many of these may make this medicine less effective or change the way it works. Tell your doctor if you are pregnant or breastfeeding.

Uses of Peg-Joxorub Solution for Infusion

Benefits of Peg-Joxorub Solution for Infusion

Cancer
Peg-Joxorub Solution for Infusion helps to treat certain kinds of cancer. It may be used alone or in combination with other medicines to treat cancer in various parts of the body. It relieves the symptoms of breast cancer such as breast lumps, bloody discharge from nipples or changes in the shape or texture of the breast. Peg-Joxorub Solution for Infusion kills or stops the growth of cancer cells and also prevents the multiplication of cancer cells. It is a potent and very toxic medicine and you should discuss the risks and benefits with your doctor. You should avoid drinking alcohol while having this treatment and drink plenty of water to stay hydrated.

Side effects of Peg-Joxorub Solution for Infusion

Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them
Common side effects of Peg-Joxorub
  • Nausea
  • Vomiting
  • Rash
  • Weakness
  • Low blood platelets
  • Fatigue
  • Fever
  • Decreased white blood cell count (neutrophils)
  • Loss of appetite
  • Anemia (low number of red blood cells)
  • Constipation
  • Stomatitis (Inflammation of the mouth)
  • Diarrhea
  • Painful blisters on hands and feet

How to use Peg-Joxorub Solution for Infusion

Your doctor or nurse will give you this medicine. Kindly do not self-administer.

How Peg-Joxorub Solution for Infusion works

Peg-Joxorub Solution for Infusion is an anti-cancer medication. It works by damaging the genetic material (DNA) of the cancer cells and stops their growth and multiplication.

Quick tips

  • Peg-Joxorub Solution for Infusion helps treat cancer of the breast, blood, and ovaries.
  • It is given through a drip into a vein (intravenous infusion) by a doctor or nurse.
  • It may make you feel tired or sleepy. Do not drive or do anything that requires mental focus until you know how it affects you.
  • Use a reliable contraceptive method to prevent pregnancy while you are taking this medicine and for 6 months after stopping treatment.
  • Inform your doctor if you notice sores, discolouration or any discomfort in your mouth.
  • Your doctor may get regular blood tests done to monitor your blood cells, liver, and heart function during treatment with this medicine.
  • Inform your doctor immediately if you notice any signs of infection such as fever, sore throat or rash.

Safety advice

Alcohol

Alcohol

CONSULT YOUR DOCTOR
It is not known whether it is safe to consume alcohol with Peg-Joxorub Solution for Infusion. Please consult your doctor.
Pregnancy

Pregnancy

CONSULT YOUR DOCTOR
Peg-Joxorub Solution for Infusion is unsafe to use during pregnancy as there is definite evidence of risk to the developing baby. However, the doctor may rarely prescribe it in some life-threatening situations if the benefits are more than the potential risks. Please consult your doctor.
Breast feeding

Breast feeding

CONSULT YOUR DOCTOR
Information regarding the use of Peg-Joxorub Solution for Infusion during breastfeeding is not available. Please consult your doctor.
Driving

Driving

UNSAFE
Peg-Joxorub Solution for Infusion may decrease alertness, affect your vision or make you feel sleepy and dizzy. Do not drive if these symptoms occur.
Kidney

Kidney

SAFE IF PRESCRIBED
Peg-Joxorub Solution for Infusion is safe to use in patients with kidney disease. No dose adjustment of Peg-Joxorub Solution for Infusion is recommended.
Caution is advised in patients with severe kidney disease as the information available is limited for use of this medicine in these patients.
Liver

Liver

CAUTION
Peg-Joxorub Solution for Infusion should be used with caution in patients with liver disease. Dose adjustment of Peg-Joxorub Solution for Infusion may be needed. Please consult your doctor.
Use of Peg-Joxorub Solution for Infusion is not recommended in patients with severe liver disease.
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Frequently asked questions

Doxorubicin is anti-cancer or antineoplastic chemotherapy drug that belongs to a class of medication called anthracyclines. It slows down or stops the growth of cancer cells by interfering with DNA of the cancer cell.
The molecules of doxorubicin are coated in a fatty capsule called as liposome. This liposome protects the body and allows the doxorubicin to remain in the blood circulation for a longer duration. This means that more amount of drug can be delivered to the cancer cells with less side effects.

Fact Box

Chemical Class

Anthracycline Derivative

Habit Forming

No

Therapeutic Class

ANTI NEOPLASTICS

Action Class

Alkaloids-cytotoxic agents

References

  1. Chabner BA, Bertino J, Cleary J, et al. Cytotoxic Agents. In: Brunton LL, Chabner BA, Knollmann BC, editors. Goodman & Gilman’s: The Pharmacological Basis of Therapeutics. 12th ed. New York, New York: McGraw-Hill Medical; 2011. pp. 1714-15.
  2. Chu E, Sartorelli AC. Cancer Chemotherapy. In: Katzung BG, Masters SB, Trevor AJ, editors. Basic and Clinical Pharmacology. 11th ed. New Delhi, India: Tata McGraw Hill Education Private Limited; 2009. p. 952.
  3. Briggs GG, Freeman RK, editors. A Reference Guide to Fetal and Neonatal Risk: Drugs in Pregnancy and Lactation. 10th ed. Philadelphia, PA: Wolters Kluwer Health; 2015. pp. 431-33.
  4. Doxorubicin hydrochloride liposome. Bedford, Ohio: Ben Venue Laboratories, Inc.; 1995 [revised May 2007]. (online) Available from:
  5. Drugs.com. Doxorubicin Pregnancy and Breastfeeding Warnings. [Accessed 27 Mar. 2019]. (online) Available from:
  6. Central Drugs Standard Control Organisation (CDSCO). [Accessed 27 Mar. 2019] (online) Available from:
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100% genuine products
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Patient concerns

Iam having three pegs brandy daily .am having lantus insulin&amaryl m aftefood.anyproblems

Dr. Sanjay Bhatt
Dr. Sanjay Bhatt
Physician
Reduce to 1 peg 30 ml twice a week

I have a fatty liver . Suggest me something which i can do without leaving alcohol. I Can minimise to three peg per week

Dr. Sunil Sekhri
Dr. Sunil Sekhri
Diabetology
Stopping alcohol is a must
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Disclaimer

Tata 1mg's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover everything about particular health conditions, lab tests, medicines, all possible side effects, drug interactions, warnings, alerts, etc. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.

Marketer details

Name: Jodas Expoim
Address: Survey No.376/A, Rajeev Gandhi Nagar ,IE,Plot no. 40, houseNo:5-9-262/40, Ground, 1st &2nd Floor, Medchal -Malkajgiri,Telanagan 500072

Vendor Details

Country of origin: India
A licensed vendor partner from your nearest location will deliver Peg-Joxorub Solution for Infusion. Once the pharmacy accepts your order, the details of the pharmacy will be shared with you. Acceptance of your order is based on the validity of your doctor's ℞ and the availability of this medicine.

In case of any issues, contact us

Email ID: [email protected]
Phone Number: 0124-4166666
Address: 5th Floor Tower - B of the Presidency Building, 46/4 Mehrauli Gurgaon Road, Sector 14, Gurugram, Haryana-122001, India
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