Pegasys 135mcg Injection
Written By Dr. Anuj Saini, MMST, MBBS
Reviewed By Dr. Varun Gupta, MD Pharmacology, MBBS
Last updated on 29 Oct 2024 | 01:09 AM (IST)
Pegasys 135mcg Injection is used in the treatment of chronic hepatitis C virus (HCV) infection and chronic hepatitis B virus (HBV) infection.
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General Information
Contains
Pegylated Interferon Alpha 2A (135mcg)
Marketer
Roche Products India Pvt Ltd
Storage
Store in a refrigerator (2 - 8°C). Do not freeze.
The content is shown in English


Product introduction
Pegasys 135mcg Injection is given as an injection by a qualified medical professional. You should continue to take it as long as your doctor advises it. The duration of treatment varies according to your need and response to treatment. You should take it exactly as your doctor has advised. Taking it in the wrong way or taking too much can cause very serious side effects. It may take several weeks or months for you to see or feel the benefits but do not stop taking it unless your doctor tells you to.
Some common side effects of this medicine include headache, sweating, joint pain, and flu-like symptoms. This medicine may reduce the number of blood cells in your blood, thereby, increasing the susceptibility to infections. Hence, inform your doctor if you notice fever, chills, rash, trouble breathing, unusual bleeding or bruising, and dark-colored urine. Regular blood tests are required to check your blood cells along with thyroid, liver, kidney, and serum electrolytes levels.
Before taking it, tell your doctor if have liver, or kidney problems or have mental illness. You must inform your doctor about mental illness, mood changes, depression, vision change, and suicidal thoughts as this medicine can worsen the situation. Many other medicines can affect, or be affected by, this medicine so let your healthcare team know all medications you are using. This medicine is not recommended during pregnancy or while breastfeeding. The use of effective contraception by both males and females during treatment is important to avoid pregnancy.
Some common side effects of this medicine include headache, sweating, joint pain, and flu-like symptoms. This medicine may reduce the number of blood cells in your blood, thereby, increasing the susceptibility to infections. Hence, inform your doctor if you notice fever, chills, rash, trouble breathing, unusual bleeding or bruising, and dark-colored urine. Regular blood tests are required to check your blood cells along with thyroid, liver, kidney, and serum electrolytes levels.
Before taking it, tell your doctor if have liver, or kidney problems or have mental illness. You must inform your doctor about mental illness, mood changes, depression, vision change, and suicidal thoughts as this medicine can worsen the situation. Many other medicines can affect, or be affected by, this medicine so let your healthcare team know all medications you are using. This medicine is not recommended during pregnancy or while breastfeeding. The use of effective contraception by both males and females during treatment is important to avoid pregnancy.
Uses of Pegasys Injection
- Chronic hepatitis C virus (HCV) infection
- Chronic hepatitis B virus (HBV) infection
Benefits of Pegasys Injection
Chronic hepatitis C virus (HCV) infection
Chronic hepatitis B virus infection is a serious infection of the liver that has been there for at least 6 months and still not cured. Pegasys 135mcg Injection helps treat this infection effectively. It lowers your chances of getting complications such as new infections and improves your quality of life. If this infection is not treated, it can lead to severe liver damage which can cause other life-threatening problems such as liver failure or may be fatal also.
Chronic hepatitis B virus infection is a serious infection of the liver that has been there for at least 6 months and still not cured. Pegasys 135mcg Injection helps treat this infection effectively. It lowers your chances of getting complications such as new infections and improves your quality of life. If this infection is not treated, it can lead to severe liver damage which can cause other life-threatening problems such as liver failure or may be fatal also.
Chronic hepatitis B virus (HBV) infection
Pegasys 135mcg Injection helps control the infection and makes the immune system work better. This lowers your chances of getting complications and improves your quality of life. This medicine is always taken in combination with other antiretroviral medicines. It is not a cure and should neither be used to prevent HCV infection. It is important that you take this medicine as prescribed, following the dosage recommended by your doctor. Taking all doses in the right amount at the right times greatly increases the effectiveness of the medicine.
Pegasys 135mcg Injection helps control the infection and makes the immune system work better. This lowers your chances of getting complications and improves your quality of life. This medicine is always taken in combination with other antiretroviral medicines. It is not a cure and should neither be used to prevent HCV infection. It is important that you take this medicine as prescribed, following the dosage recommended by your doctor. Taking all doses in the right amount at the right times greatly increases the effectiveness of the medicine.
Side effects of Pegasys Injection
Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them
Common side effects of Pegasys
- Headache
- Sweating
- Joint pain
- Flu-like symptoms
- Muscle pain
- Vomiting
- Nausea
- Decreased white blood cell count
- Hair loss
- Rigors
- Decreased appetite
- Fatigue
- Decreased calcium level in blood
- Diarrhea
How to use Pegasys Injection
Your doctor or nurse will give you this medicine. Kindly do not self administer.
How Pegasys Injection works
Pegasys 135mcg Injection modulates the body's immune system.
All substitutes for Pegasys 135mcg Injection
For information purposes only. Consult a doctor before taking any medicine.
Quick tips
- Pegasys 135mcg Injection helps treat chronic hepatitis B in adults.
- It may also be used in combination with other medicines for the treatment of chronic hepatitis C.
- Do not drive or do anything that requires mental focus until you know how it affects you.
- Use a reliable contraceptive method to prevent pregnancy while you are taking this medicine and 4 months after stopping the treatment.
- Your doctor may get regular blood tests done to monitor your blood cells, liver and thyroid function, and lipid levels during treatment with this medicine.
- Inform your doctor immediately if you notice any signs of infection such as fever, sore throat or rash.
- Inform your doctor if you notice any changes in your behavior, mood or vision.
Safety advice

Alcohol
CAUTION
Caution is advised when consuming alcohol with Pegasys 135mcg Injection. Please consult your doctor.

Pregnancy
CONSULT YOUR DOCTOR
Pegasys 135mcg Injection may be unsafe to use during pregnancy. Although there are limited studies in humans, animal studies have shown harmful effects on the developing baby. Your doctor will weigh the benefits and any potential risks before prescribing it to you. Please consult your doctor.

Breast feeding
SAFE IF PRESCRIBED
Pegasys 135mcg Injection is probably safe to use during breastfeeding. Limited human data suggests that the drug does not represent any significant risk to the baby.

Driving
UNSAFE
Pegasys 135mcg Injection may cause side effects which could affect your ability to drive.
Patients may develop dizziness, confusion, somnolence, and fatigue while on Pegasys 135mcg Injection and should be cautioned to avoid driving.
Patients may develop dizziness, confusion, somnolence, and fatigue while on Pegasys 135mcg Injection and should be cautioned to avoid driving.

Kidney
CAUTION
Pegasys 135mcg Injection should be used with caution in patients with kidney disease. Dose adjustment of Pegasys 135mcg Injection may be needed. Please consult your doctor.

Liver
SAFE IF PRESCRIBED
Pegasys 135mcg Injection is probably safe to use in patients with liver disease. Limited data available suggests that dose adjustment of Pegasys 135mcg Injection may not be needed in these patients. Please consult your doctor.
Regular monitoring of liver function tests is advised while you are taking this medicine.
Regular monitoring of liver function tests is advised while you are taking this medicine.

Fact Box
Chemical Class
Interferons
Habit Forming
No
Therapeutic Class
ANTI NEOPLASTICS
Action Class
Interferons
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Patient concerns
How to treatment of HEPATITIS C VIRUS
Dr. Deepak Kumar Soni
Ayurveda
https://www.1mg.com/otc/himalaya-liv.-52-ds-tablet-otc135545One ?one tablet morning & evening after taking food , use at least 1-2 monthsUse this medicine along with your treatment
I am affected from hepatitis c virus diagnosed with confirmed genotype. Meanwhile i am pregnant will hepatitis virus pass on my baby. Or i should abort
Dr. Kunal Parasar
Surgical Gastroenterology
Your reports are of february with no ongoin liver damage. You havnt got the quantitative analysis. Most probably you wont need to abort. But be in constant follow up of good gastroenterologist near you.
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Tata 1mg's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover everything about particular health conditions, lab tests, medicines, all possible side effects, drug interactions, warnings, alerts, etc. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.
Marketer details
Name: Roche Products India Pvt Ltd
Address: 1503, 15th Floor, ‘The Capital’, Plot no. C-70, Behind ICICI Bank, BKC, Bandra (E) , Mumbai 400051
Address: 1503, 15th Floor, ‘The Capital’, Plot no. C-70, Behind ICICI Bank, BKC, Bandra (E) , Mumbai 400051
Vendor Details
Country of origin: India
Lab tests offered by us
- CBC (Complete Blood Count)
- FBS (Fasting Blood Sugar)
- Thyroid Profile Total (T3, T4 & TSH)
- HbA1c (Glycosylated Hemoglobin)
- Glucose - Postprandial
- Lipid Profile
- Vitamin D (25-Hydroxy)
- Urine R/M (Urine Routine & Microscopy)
- Coronavirus Covid-19 Test (RT-PCR technique)
- LFT (Liver Function Test)
- Kidney Function Test
- TSH (Thyroid Stimulating Hormone) Ultrasensitive
- ESR (Erythrocyte Sedimentation Rate)
- Uric Acid
- Vitamin B12
- C- Reactive Protein Quantitative
- Urine Culture and Sensitivity
- Serum Electrolyte
- Serum Calcium
- Creatinine
- Diabetes Screening
- KFT with Electrolytes (Kidney Function Test with Electrolytes)
- Cholesterol - Total
- Hemoglobin
- Complete Haemogram
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