Pgbest-NT Tablet
Written By Dr. Swati Mishra, BDS
Reviewed By Dr. Ashish Ranjan, MD (Pharmacology), MBBS
Last updated on 11 Nov 2024 | 01:00 AM (IST)
Pgbest-NT Tablet is a combination medicine used for the treatment of neuropathic pain. This medicine decreases the pain by stopping the movement of pain signals to the brain.
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MRP ₹198
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General Information
Contains
Pregabalin (75mg)+ Nortriptyline (10mg)
Marketer
Alathea Biotec Pvt Ltd
Storage
Store below 30°C
The content is shown in English
Product introduction
Pgbest-NT Tablet is taken by mouth, with or without food and preferably at bedtime. It is advised to take it at the same time each day as this helps to maintain a consistent level of medicine in the blood. Take this medicine in the dose and duration advised by your doctor as this is a habit-forming medicine. If you miss a dose of this medicine, take it as soon as you remember. Finish the full course of treatment even if you feel better. It is important not to stop this medication suddenly without talking to the doctor.
Some common side effects of this medicine include constipation, difficulty in urination, weight gain, tiredness, and dryness in mouth. It may also cause dizziness and sleepiness. So, do not drive or do anything that requires mental focus until you know how this medicine affects you. This medicine may cause weight gain and to control it, you should exercise regularly and take a balanced diet. It is important to inform your doctor if you develop any unusual changes in mood or behavior, new or worsening depression, or suicidal thoughts.
Before taking this medicine let your doctor know if you suffer from kidney or liver disease. Your doctor should also know about all other medicines you are taking as many of these may make this medicine less effective or change the way it works. Inform your doctor if you are pregnant, planning pregnancy or breastfeeding.
Uses of Pgbest-NT Tablet
Benefits of Pgbest-NT Tablet
Treatment of Neuropathic pain
Pgbest-NT Tablet is a combination of medicines used to treat long-lasting (chronic) pain caused by nerve damage due to diabetes, shingles, or spinal cord injury. It reduces pain and its associated symptoms such as mood changes, sleep problems, and tiredness. It is thought to work by interfering with pain signals that travel through the damaged nerves and the brain.
Taking Pgbest-NT Tablet regularly will improve your physical and social functioning and overall quality of life. It takes a few weeks to work so you need to take it regularly even if you feel it is not doing any good. Once your symptoms have gone you should still keep taking the medicine until your doctor advises you to stop.
Pgbest-NT Tablet is a combination of medicines used to treat long-lasting (chronic) pain caused by nerve damage due to diabetes, shingles, or spinal cord injury. It reduces pain and its associated symptoms such as mood changes, sleep problems, and tiredness. It is thought to work by interfering with pain signals that travel through the damaged nerves and the brain.
Taking Pgbest-NT Tablet regularly will improve your physical and social functioning and overall quality of life. It takes a few weeks to work so you need to take it regularly even if you feel it is not doing any good. Once your symptoms have gone you should still keep taking the medicine until your doctor advises you to stop.
Side effects of Pgbest-NT Tablet
Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them
Common side effects of Pgbest-NT
- Dryness in mouth
- Increased heart rate
- Sleepiness
- Dizziness
- Tiredness
- Weight gain
- Blurred vision
- Orthostatic hypotension (sudden lowering of blood pressure on standing)
- Uncoordinated body movements
- Increased appetite
- Increased libido
- Paresthesia (tingling or pricking sensation)
- Vertigo
- Vomiting
- Nausea
- Erectile dysfunction
- Joint pain
- Constipation
- Difficulty in urination
How to use Pgbest-NT Tablet
Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Pgbest-NT Tablet may be taken with or without food, but it is better to take it at a fixed time.
How Pgbest-NT Tablet works
Pgbest-NT Tablet is a combination of two medicines: Pregabalin and Nortriptyline. Pregabalin is an alpha 2 delta ligand which decreases the pain by modulating calcium channel activity of the nerve cells. Nortriptyline is a tricyclic antidepressant which increases the levels of chemical messengers (serotonin and noradrenaline) that stop the movement of pain signals in the brain. Together, they relieve neuropathic pain (pain from damaged nerves).
Quick tips
- Pgbest-NT Tablet is used to treat certain types of long-lasting pain caused by damage to nerves.
- Inform your doctor if you are taking any other pain-relieving medicines.
- Inform your doctor if you have a history of seizures.
- Immediately seek medical help if you experience hallucinations, fever, sweating, shivering, fast heart rate, muscle twitching, or loss of coordination.
- Along with taking Pgbest-NT Tablet, your doctor might advise you to undergo physiotherapy to get relief from pain.
- Pgbest-NT Tablet is used to treat certain types of long-lasting pain caused by damage to nerves.
- Inform your doctor if you are taking any other pain-relieving medicines.
- Inform your doctor if you have a history of seizures.
- Immediately seek medical help if you experience hallucinations, fever, sweating, shivering, fast heart rate, muscle twitching, or loss of coordination.
- Along with taking Pgbest-NT Tablet, your doctor might advise you to undergo physiotherapy to get relief from pain.
Safety advice
Alcohol
UNSAFE
Pgbest-NT Tablet may cause excessive drowsiness with alcohol.
Pregnancy
CONSULT YOUR DOCTOR
Pgbest-NT Tablet may be unsafe to use during pregnancy. Although there are limited studies in humans, animal studies have shown harmful effects on the developing baby. Your doctor will weigh the benefits and any potential risks before prescribing it to you. Please consult your doctor.
Breast feeding
CONSULT YOUR DOCTOR
Pgbest-NT Tablet is probably unsafe to use during breastfeeding. Limited human data suggests that the drug may pass into the breastmilk and harm the baby.
Driving
UNSAFE
Pgbest-NT Tablet may cause side effects which could affect your ability to drive.
As Pgbest-NT Tablet may affect your alertness which may affect your ability to drive.
As Pgbest-NT Tablet may affect your alertness which may affect your ability to drive.
Kidney
CAUTION
Pgbest-NT Tablet should be used with caution in patients with kidney disease. Dose adjustment of Pgbest-NT Tablet may be needed. Please consult your doctor.
Liver
SAFE IF PRESCRIBED
Pgbest-NT Tablet is probably safe to use in patients with liver disease. Limited data available suggests that dose adjustment of Pgbest-NT Tablet may not be needed in these patients. Please consult your doctor.
Frequently asked questions
Pgbest-NT Tablet is a combination of two medicines: Pregabalin and Nortriptyline. This medicine is useful in the treatment of nerve pain (neuropathic pain). It calms the damaged or overactive nerves by acting on the brain. Thereby, decreasing the pain sensation.
No, you should not stop taking Pgbest-NT Tablet even if your pain is relieved. Continue to take it as advised by your doctor. If you suddenly stop taking Pgbest-NT Tablet, you may experience withdrawal symptoms such as anxiety, sleeping difficulties, nausea, pain and sweating. You may need to gradually taper the dose before you stop the medication completely.
Pgbest-NT Tablet can make you feel hungry which might make you eat more, thereby increasing your chances of putting on weight.. However, preventing weight gain is easier than losing increased weight. Try to eat a healthy balanced diet without increasing your portion sizes (per-meal intake). DO not eat foods that contain a lot of calories, such as soft drinks, oily food, chips, cakes, biscuits, and sweets. If you feel hungry between meals, avoid eating junk food and eat fruits, vegetables and low-calorie foods. Regular exercise will prevent weight gain. If you maintain good eating habits and exercise regularly, you might not gain any weight.
Yes, Pgbest-NT Tablet may make you feel drowsy or you may suddenly fall asleep during your daily activities. Sometimes, you might not even feel drowsy or have any other warning signs before you suddenly fall asleep. Avoid driving a car, operating machinery, working at heights or participating in potentially dangerous activities at the beginning of your treatment until you know how the medicine affects you. Inform your doctor if you experience such episodes while taking this medicine.
The use of Pgbest-NT Tablet can affect the sexual life of both men and women. Most commonly caused problems are decreased sexual desire, erectile dysfunction (inability to develop or maintain erection during the sexual activity) and inability to reach orgasm. It can also cause a decrease in satisfaction and cause discomfort while intercourse. If you experience these problems, discuss them with your doctor but do not stop taking Pgbest-NT Tablet.
Serious side effects because of Pgbest-NT Tablet are uncommon and rare. Consult your doctor if you notice any of the following: changes in body temperature, difficulty in breathing, increased heartbeat (palpitations), weakness, unsteadiness when walking, reduced coordination or slowed reactions, unusual changes in mood or behavior (such as restlessness, nervousness or excitement), signs of depression, seeing or hearing things that are not there, irrational thinking, blurred or double vision, uncontrollable jerky eye movements, difficulty seeing, signs of frequent infections such as fever, severe chills, sore throat or mouth ulcers. These side effects are uncommon but may be serious and need urgent medical attention.
An initial benefit with Pgbest-NT Tablet may be seen after 2 weeks of treatment. However, it may take around 2-3 months to see full benefit. It may even take longer in some patients.
If you forget to take the scheduled dose of Pgbest-NT Tablet and it is almost time for your next dose, skip the dose you missed and take your next dose at the scheduled time. Otherwise, take it as soon as you remember, and then go back to taking your medicine as you would normally. Do not take a double dose to make up for the dose you missed because this may increase the risk of unwanted side effects due to overdosage. If you are not sure what to do, consult your doctor about how to manage a situation like this.
In a situation like this, contact your doctor immediately or seek emergency help at the nearest hospital. Do this even if there are no signs of discomfort or poisoning. You may need urgent medical attention. Symptoms of an overdose may include drowsiness, weakness, unsteadiness while walking, having double visions, slurred speech or diarrhea, confusion, blurred vision, dizziness, body temperature changes (low and high), difficulty in breathing and increased heartbeat.
No, taking a higher than the recommended dose may not be more effective, rather it may increase the chances of having some serious side effects and toxicity. If you experience increased severity of your symptoms that are not relieved by the recommended doses, please consult your doctor for re-evaluation.
Pgbest-NT Tablet may impair your thinking or reactions. Be careful while driving or doing an activity that requires you to be alert. Do not drink alcohol while you are taking Pgbest-NT Tablet. It can increase the effects of alcohol, which could be dangerous. Grapefruit and grapefruit juice may also interact with this medicine and cause unwanted side effects. Avoid exposure to sunlight or tanning beds. Use of Pgbest-NT Tablet can make you more prone to sunburns. Wear protective clothing and use sunscreen when you are outdoors during daytime.
You may need to see your doctor regularly if you have started to take Pgbest-NT Tablet. However, you must consult your doctor if the advised dosage of Pgbest-NT Tablet does not improve your symptoms or you continue experiencing some unwanted side effects that affect your routine activities.
Keep your tablets in the pack until it is time to take them. Store them in a cool and dry place. Store them out of sight and reach of the children. Unused medications should be disposed of in special ways to ensure that pets, children and other people cannot consume them.
Pgbest-NT Tablet is a combination of two medicines: Pregabalin and Nortriptyline. This medicine is useful in the treatment of nerve pain (neuropathic pain). It calms the damaged or overactive nerves by acting on the brain. Thereby, decreasing the pain sensation.
No, you should not stop taking Pgbest-NT Tablet even if your pain is relieved. Continue to take it as advised by your doctor. If you suddenly stop taking Pgbest-NT Tablet, you may experience withdrawal symptoms such as anxiety, sleeping difficulties, nausea, pain and sweating. You may need to gradually taper the dose before you stop the medication completely.
Pgbest-NT Tablet can make you feel hungry which might make you eat more, thereby increasing your chances of putting on weight.. However, preventing weight gain is easier than losing increased weight. Try to eat a healthy balanced diet without increasing your portion sizes (per-meal intake). DO not eat foods that contain a lot of calories, such as soft drinks, oily food, chips, cakes, biscuits, and sweets. If you feel hungry between meals, avoid eating junk food and eat fruits, vegetables and low-calorie foods. Regular exercise will prevent weight gain. If you maintain good eating habits and exercise regularly, you might not gain any weight.
Yes, Pgbest-NT Tablet may make you feel drowsy or you may suddenly fall asleep during your daily activities. Sometimes, you might not even feel drowsy or have any other warning signs before you suddenly fall asleep. Avoid driving a car, operating machinery, working at heights or participating in potentially dangerous activities at the beginning of your treatment until you know how the medicine affects you. Inform your doctor if you experience such episodes while taking this medicine.
The use of Pgbest-NT Tablet can affect the sexual life of both men and women. Most commonly caused problems are decreased sexual desire, erectile dysfunction (inability to develop or maintain erection during the sexual activity) and inability to reach orgasm. It can also cause a decrease in satisfaction and cause discomfort while intercourse. If you experience these problems, discuss them with your doctor but do not stop taking Pgbest-NT Tablet.
Serious side effects because of Pgbest-NT Tablet are uncommon and rare. Consult your doctor if you notice any of the following: changes in body temperature, difficulty in breathing, increased heartbeat (palpitations), weakness, unsteadiness when walking, reduced coordination or slowed reactions, unusual changes in mood or behavior (such as restlessness, nervousness or excitement), signs of depression, seeing or hearing things that are not there, irrational thinking, blurred or double vision, uncontrollable jerky eye movements, difficulty seeing, signs of frequent infections such as fever, severe chills, sore throat or mouth ulcers. These side effects are uncommon but may be serious and need urgent medical attention.
An initial benefit with Pgbest-NT Tablet may be seen after 2 weeks of treatment. However, it may take around 2-3 months to see full benefit. It may even take longer in some patients.
If you forget to take the scheduled dose of Pgbest-NT Tablet and it is almost time for your next dose, skip the dose you missed and take your next dose at the scheduled time. Otherwise, take it as soon as you remember, and then go back to taking your medicine as you would normally. Do not take a double dose to make up for the dose you missed because this may increase the risk of unwanted side effects due to overdosage. If you are not sure what to do, consult your doctor about how to manage a situation like this.
In a situation like this, contact your doctor immediately or seek emergency help at the nearest hospital. Do this even if there are no signs of discomfort or poisoning. You may need urgent medical attention. Symptoms of an overdose may include drowsiness, weakness, unsteadiness while walking, having double visions, slurred speech or diarrhea, confusion, blurred vision, dizziness, body temperature changes (low and high), difficulty in breathing and increased heartbeat.
No, taking a higher than the recommended dose may not be more effective, rather it may increase the chances of having some serious side effects and toxicity. If you experience increased severity of your symptoms that are not relieved by the recommended doses, please consult your doctor for re-evaluation.
Pgbest-NT Tablet may impair your thinking or reactions. Be careful while driving or doing an activity that requires you to be alert. Do not drink alcohol while you are taking Pgbest-NT Tablet. It can increase the effects of alcohol, which could be dangerous. Grapefruit and grapefruit juice may also interact with this medicine and cause unwanted side effects. Avoid exposure to sunlight or tanning beds. Use of Pgbest-NT Tablet can make you more prone to sunburns. Wear protective clothing and use sunscreen when you are outdoors during daytime.
You may need to see your doctor regularly if you have started to take Pgbest-NT Tablet. However, you must consult your doctor if the advised dosage of Pgbest-NT Tablet does not improve your symptoms or you continue experiencing some unwanted side effects that affect your routine activities.
Keep your tablets in the pack until it is time to take them. Store them in a cool and dry place. Store them out of sight and reach of the children. Unused medications should be disposed of in special ways to ensure that pets, children and other people cannot consume them.
Pgbest-NT Tablet is a combination of two medicines: Pregabalin and Nortriptyline. This medicine is useful in the treatment of nerve pain (neuropathic pain). It calms the damaged or overactive nerves by acting on the brain. Thereby, decreasing the pain sensation.
No, you should not stop taking Pgbest-NT Tablet even if your pain is relieved. Continue to take it as advised by your doctor. If you suddenly stop taking Pgbest-NT Tablet, you may experience withdrawal symptoms such as anxiety, sleeping difficulties, nausea, pain and sweating. You may need to gradually taper the dose before you stop the medication completely.
Pgbest-NT Tablet can make you feel hungry which might make you eat more, thereby increasing your chances of putting on weight.. However, preventing weight gain is easier than losing increased weight. Try to eat a healthy balanced diet without increasing your portion sizes (per-meal intake). DO not eat foods that contain a lot of calories, such as soft drinks, oily food, chips, cakes, biscuits, and sweets. If you feel hungry between meals, avoid eating junk food and eat fruits, vegetables and low-calorie foods. Regular exercise will prevent weight gain. If you maintain good eating habits and exercise regularly, you might not gain any weight.
Yes, Pgbest-NT Tablet may make you feel drowsy or you may suddenly fall asleep during your daily activities. Sometimes, you might not even feel drowsy or have any other warning signs before you suddenly fall asleep. Avoid driving a car, operating machinery, working at heights or participating in potentially dangerous activities at the beginning of your treatment until you know how the medicine affects you. Inform your doctor if you experience such episodes while taking this medicine.
The use of Pgbest-NT Tablet can affect the sexual life of both men and women. Most commonly caused problems are decreased sexual desire, erectile dysfunction (inability to develop or maintain erection during the sexual activity) and inability to reach orgasm. It can also cause a decrease in satisfaction and cause discomfort while intercourse. If you experience these problems, discuss them with your doctor but do not stop taking Pgbest-NT Tablet.
Serious side effects because of Pgbest-NT Tablet are uncommon and rare. Consult your doctor if you notice any of the following: changes in body temperature, difficulty in breathing, increased heartbeat (palpitations), weakness, unsteadiness when walking, reduced coordination or slowed reactions, unusual changes in mood or behavior (such as restlessness, nervousness or excitement), signs of depression, seeing or hearing things that are not there, irrational thinking, blurred or double vision, uncontrollable jerky eye movements, difficulty seeing, signs of frequent infections such as fever, severe chills, sore throat or mouth ulcers. These side effects are uncommon but may be serious and need urgent medical attention.
An initial benefit with Pgbest-NT Tablet may be seen after 2 weeks of treatment. However, it may take around 2-3 months to see full benefit. It may even take longer in some patients.
If you forget to take the scheduled dose of Pgbest-NT Tablet and it is almost time for your next dose, skip the dose you missed and take your next dose at the scheduled time. Otherwise, take it as soon as you remember, and then go back to taking your medicine as you would normally. Do not take a double dose to make up for the dose you missed because this may increase the risk of unwanted side effects due to overdosage. If you are not sure what to do, consult your doctor about how to manage a situation like this.
In a situation like this, contact your doctor immediately or seek emergency help at the nearest hospital. Do this even if there are no signs of discomfort or poisoning. You may need urgent medical attention. Symptoms of an overdose may include drowsiness, weakness, unsteadiness while walking, having double visions, slurred speech or diarrhea, confusion, blurred vision, dizziness, body temperature changes (low and high), difficulty in breathing and increased heartbeat.
No, taking a higher than the recommended dose may not be more effective, rather it may increase the chances of having some serious side effects and toxicity. If you experience increased severity of your symptoms that are not relieved by the recommended doses, please consult your doctor for re-evaluation.
Pgbest-NT Tablet may impair your thinking or reactions. Be careful while driving or doing an activity that requires you to be alert. Do not drink alcohol while you are taking Pgbest-NT Tablet. It can increase the effects of alcohol, which could be dangerous. Grapefruit and grapefruit juice may also interact with this medicine and cause unwanted side effects. Avoid exposure to sunlight or tanning beds. Use of Pgbest-NT Tablet can make you more prone to sunburns. Wear protective clothing and use sunscreen when you are outdoors during daytime.
You may need to see your doctor regularly if you have started to take Pgbest-NT Tablet. However, you must consult your doctor if the advised dosage of Pgbest-NT Tablet does not improve your symptoms or you continue experiencing some unwanted side effects that affect your routine activities.
Keep your tablets in the pack until it is time to take them. Store them in a cool and dry place. Store them out of sight and reach of the children. Unused medications should be disposed of in special ways to ensure that pets, children and other people cannot consume them.
Fact Box
Habit Forming
No
Therapeutic Class
NEURO CNS
References
- Pregabalin. Vega Baja, Puerto Rico: Pfizer Pharmaceuticals LLC; 2009. [Accessed 22 Apr. 2019] (online) Available from:
- Pregabalin. New York, New York: Pfizer; 2004 [revised Jun 2011]. [Accessed 22 Apr. 2019] (online) Available from:
- Pregabalin and Nortriptyline [Product Information]. Ahmedabad, Gujarat: La Renon Healthcare Limited. [Accessed 28th Sept. 2023] (online) Available from:
- Pregabalin+Nortriptyline [Prescribing Information]. Mumbai, Maharashtra: Alkem Laboratories Limited. [Accessed 28th Sept. 2023] (online) Available from:
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Marketer details
Name: Alathea Biotec Pvt Ltd
Address: Flat No G7, Chitra Residency, Lekha Nagar Road, Danapur, Khagaul Patna Br 801503 India
Address: Flat No G7, Chitra Residency, Lekha Nagar Road, Danapur, Khagaul Patna Br 801503 India
Vendor Details
Country of origin: India
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