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Pivikto 250mg Tablet

Written By Dr. Sakshi Jain, MS, BDS
Reviewed By Dr. Rajeev Sharma, MBA, MBBS
Last updated on 12 Nov 2024 | 01:11 AM (IST)
Pivikto 250mg Tablet is used to treat certain types of breast cancer, like hormone receptor (HR)-positive, human epidermal growth factor receptor 2 (HER2)-negative, PIK3CAmutated, advanced or breast cancer which has spread to other organs. It is given together with hormonal anticancer therapies.
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General Information

Contains

Alpelisib (250mg)

Marketer

Novartis India Ltd
The content is shown in English
Pivikto 250mg Tablet image

Product introduction

Pivikto 250mg Tablet should be taken with food, but try to take it at the same time every day to get the most benefits. Your doctor will decide what dose is necessary and how often you need to take it. This will depend on what you are being treated for and may change from time to time. Take it exactly as advised by the doctor. Taking it the wrong way or taking too much can cause very serious side effects. It may take several weeks or months for you to see or feel the benefits but do not stop taking it unless your doctor tells you to.

Some common side effects of this medicine include fatigue, decreased appetite, rash, vomiting, and diarrhea. It may reduce the number of blood cells (decrease red blood and white blood cells) in your blood, thereby increasing the susceptibility to infections. It is better to inform your doctor if you notice symptoms of infection like fever, chills, weakness, bleeding or bruising, and nose bleeding. It might also cause dizziness; so avoid driving or attention-seeking activities if you experience dizziness.

Before taking Pivikto 250mg Tablet, tell your doctor if you have heart disease, liver or kidney problems, or are taking any medicines to treat infections. Many other medicines can affect, or be affected by, this medicine, so let your healthcare team know about all the medications you are using. This medicine is not recommended during pregnancy or while breastfeeding. Use of effective contraception by both males and females during the treatment with this drug is important to avoid pregnancy.

There is a Patient Support Program/Patient Assistance Program available in India for this medicine, being managed by Tata 1mg. Please contact your prescribing doctor to know more about the same. You may also call on (1800-102-1618) for more details.

Uses of Pivikto Tablet

Benefits of Pivikto Tablet

Treatment of Breast cancer
Pivikto 250mg Tablet helps treat breast cancer, and it may be used alone or in combination with other medicines or treatment modalities, like chemotherapy. It relieves the symptoms of breast cancer, such as breast lumps, bloody discharge from nipples, or changes in the shape or texture of the breast. Pivikto 250mg Tablet kills or stops the growth of cancer cells and also prevents their multiplication. Discuss with your doctor if any of the side effects bother you.

Side effects of Pivikto Tablet

Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them
Common side effects of Pivikto
  • Diarrhea
  • Rash
  • Increased glucose level in blood
  • Nausea
  • Vomiting
  • Fatigue
  • Increased creatinine level in blood
  • Lymphocytopenia
  • Increased gamma-glutamyltransferase
  • Increased alanine aminotransferase
  • Decreased hemoglobin
  • Increased lipase in the blood
  • Decreased appetite
  • Stomatitis (Inflammation of the mouth)
  • Weight loss
  • Hypoglycemia (low blood glucose level)
  • Decreased calcium level in blood
  • Prolonged activated partial thromboplastin time (aPTT)
  • Hair loss

How to use Pivikto Tablet

Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Pivikto 250mg Tablet is to be taken with food.

How Pivikto Tablet works

Pivikto 250mg Tablet works to treat cancer by blocking the signals that cause cancer cells to multiply, which helps to stop the spread of cancer cells.

Quick tips

  • After starting your treatment with Pivikto 250mg Tablet, you may be at risk of infection, so try to avoid crowds or people with colds. Report fever or any other signs of infection immediately to your doctor.
  • Drink at least two to three-quarter fluid every 24 hours, unless you are instructed otherwise.
  • To reduce nausea, take antinausea medications as prescribed by your doctor, and eat small, frequent meals.
  • Inform your doctor if you notice any signs or symptoms of allergic reactions, like rash or shortness of breath, after taking Pivikto 250mg Tablet.
  • Monitor your sugar levels at intervals and report to your doctor if they are abnormally high. The doctor will be able to advise more on this.
  • Eat foods that may help reduce diarrhea and take adequate rest.
  • Use a soft toothbrush and rinse your mouth at least 3 times a day with saline water to help treat/prevent mouth sores.
  • After starting your treatment with Pivikto 250mg Tablet, you may be at risk of infection, so try to avoid crowds or people with colds. Report fever or any other signs of infection immediately to your doctor.
  • Drink at least two to three-quarter fluid every 24 hours, unless you are instructed otherwise.
  • To reduce nausea, take antinausea medications as prescribed by your doctor, and eat small, frequent meals.
  • Inform your doctor if you notice any signs or symptoms of allergic reactions, like rash or shortness of breath, after taking Pivikto 250mg Tablet.
  • Monitor your sugar levels at intervals and report to your doctor if they are abnormally high. The doctor will be able to advise more on this.
  • Eat foods that may help reduce diarrhea and take adequate rest.
  • Use a soft toothbrush and rinse your mouth at least 3 times a day with saline water to help treat/prevent mouth sores.

Safety advice

Alcohol

Alcohol

CONSULT YOUR DOCTOR
It is not known whether it is safe to consume alcohol with Pivikto 250mg Tablet. Please consult your doctor.
Pregnancy

Pregnancy

CONSULT YOUR DOCTOR
Pivikto 250mg Tablet may be unsafe to use during pregnancy. Although there are limited studies in humans, animal studies have shown harmful effects on the developing baby. Your doctor will weigh the benefits and any potential risks before prescribing it to you. Please consult your doctor.
Breast feeding

Breast feeding

CONSULT YOUR DOCTOR
Pivikto 250mg Tablet is probably unsafe to use during breastfeeding. Limited human data suggests that the drug may pass into the breastmilk and harm the baby.
Driving

Driving

CONSULT YOUR DOCTOR
It is not known whether Pivikto 250mg Tablet alters the ability to drive. Do not drive if you experience any symptoms that affect your ability to concentrate and react.
Kidney

Kidney

CONSULT YOUR DOCTOR
There is limited information available on the use of Pivikto 250mg Tablet in patients with kidney disease. Please consult your doctor.
Liver

Liver

SAFE IF PRESCRIBED
Pivikto 250mg Tablet is safe to use in patients with liver disease. No dose adjustment of Pivikto 250mg Tablet is recommended.

Fact Box

Chemical Class

Proline and derivatives

Habit Forming

No

Therapeutic Class

ANTI NEOPLASTICS

Action Class

Anticancer-others

Related lab tests

Breast Cancer (CA 15.3/ ER/ PR)

References

  1. Alpelisib [Prescribing Information]. East Hanover, New Jersey: Novartis Pharmaceuticals Corporation; 2022. [Accessed 22 Feb. 2023]. (online) Available from:

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Patient concerns

If any symtom of brest cancer if have whats the cure

Dr. Sanjay Singh Rai
Dr. Sanjay Singh Rai
Medical Oncology and Hematology
First is confirmation of breast cancerChance of cure depends on stage of cancer

BREAST CANCER , PET REPORT SAYS INFECTION IN SKELETON.

Dr. Sanjay Singh Rai
Dr. Sanjay Singh Rai
Medical Oncology and Hematology
Metastatic breast cancer, send me previous treatment details
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Disclaimer

Tata 1mg's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover everything about particular health conditions, lab tests, medicines, all possible side effects, drug interactions, warnings, alerts, etc. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.

Marketer details

Name: Novartis India Ltd
Address: Sandoz House, Shiv Sagar Estate, Worli Mumbai -400 018, India

Vendor Details

Country of origin: Switzerland
A licensed vendor partner from your nearest location will deliver Pivikto 250mg Tablet. Once the pharmacy accepts your order, the details of the pharmacy will be shared with you. Acceptance of your order is based on the validity of your doctor's â„ž and the availability of this medicine.

In case of any issues, contact us

Email ID: [email protected]
Phone Number: 0124-4166666
Address: 5th Floor Tower - B of the Presidency Building, 46/4 Mehrauli Gurgaon Road, Sector 14, Gurugram, Haryana-122001, India

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