Pradaxa 110mg Capsule
Written By Dr. Betina Chandolia, MDS, BDS
Reviewed By Dr. Lalit Kanodia, MBA, MD Pharmacology
Last updated on 12 Nov 2024 | 01:07 AM (IST)
Pradaxa 110mg Capsule is an anticoagulant or blood thinner. It helps prevent and treat blood clots. It is used to reduce the risk of stroke and heart attack. It prevents and treats clot formation in the veins of your legs, lungs, brain, and heart.
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Product introduction
Pradaxa 110mg Capsule is commonly used in patients with irregular heart rhythm (atrial fibrillation) to prevent clot formation. It also reduces the risk of getting clots in people who have undergone knee or hip replacement surgeries. It can be taken with or without food, but it is best to take them at the same time each day. You may need to take this medicine for many years, even for life in some cases. Do not stop taking it or change the dose without guidance from your doctor. It could quickly put you more at risk of having a heart attack, stroke, or thrombosis (formation of a blood clot within a blood vessel). You can reduce your risk of having a blood clot by making changes to your lifestyle, such as not smoking, eating a healthy diet, getting regular exercise, and losing weight if you need to.
The most common side effect of Pradaxa 110mg Capsule are stomach upset and bleeding more easily than normal, for example having nosebleeds or bruising. If you experience any symptoms, tell your doctor immediately. Other side effects include headaches, seizures, allergic reactions, changes to your eyesight, and tiredness.
Do not take this medicine if you have severe kidney or liver problems, if you are currently bleeding or if you are taking other medicines to reduce blood clotting. You should not breastfeed while using this medicine. Unlike other anticoagulants, a regular blood test (PT-INR) is not required while taking this medicine.
The most common side effect of Pradaxa 110mg Capsule are stomach upset and bleeding more easily than normal, for example having nosebleeds or bruising. If you experience any symptoms, tell your doctor immediately. Other side effects include headaches, seizures, allergic reactions, changes to your eyesight, and tiredness.
Do not take this medicine if you have severe kidney or liver problems, if you are currently bleeding or if you are taking other medicines to reduce blood clotting. You should not breastfeed while using this medicine. Unlike other anticoagulants, a regular blood test (PT-INR) is not required while taking this medicine.
Uses of Pradaxa Capsule
- Treatment and prevention of Blood clots
Benefits of Pradaxa Capsule
Treatment and prevention of Blood clots
Pradaxa 110mg Capsule is a type of medicine known as an anticoagulant. Although it does not “dissolve” blood clots, it can prevent them from getting bigger so your body can dissolve them over time. It will also prevent new ones from forming. It works by blocking a substance in the body which is involved in blood clotting. This keeps your blood flowing freely around your body and makes it less likely that a clot will form inside a blood vessel. This can help prevent or reduce damage caused by stroke, clots in your lungs (pulmonary embolism), or other blood vessels (thrombosis). It can also make it less likely that parts of a clot will break off and travel to other parts of the body. You should take it regularly and make appropriate lifestyle changes to help this medicine be effective.
Pradaxa 110mg Capsule is a type of medicine known as an anticoagulant. Although it does not “dissolve” blood clots, it can prevent them from getting bigger so your body can dissolve them over time. It will also prevent new ones from forming. It works by blocking a substance in the body which is involved in blood clotting. This keeps your blood flowing freely around your body and makes it less likely that a clot will form inside a blood vessel. This can help prevent or reduce damage caused by stroke, clots in your lungs (pulmonary embolism), or other blood vessels (thrombosis). It can also make it less likely that parts of a clot will break off and travel to other parts of the body. You should take it regularly and make appropriate lifestyle changes to help this medicine be effective.
Side effects of Pradaxa Capsule
Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them
Common side effects of Pradaxa
- Nausea
- Anemia (low number of red blood cells)
- Gastrointestinal bleeding
- Dyspepsia
- Diarrhea
- Abdominal pain
- Nosebleeds
- Skin bleeding
How to use Pradaxa Capsule
Take this medicine in the dose and duration as advised by your doctor. Pradaxa 110mg Capsule may be taken with or without food, but it is better to take it at a fixed time.
How Pradaxa Capsule works
Pradaxa 110mg Capsule is a novel oral anticoagulant (NOAC). It works by preventing the formation of blood clots in the body.
All substitutes for Pradaxa 110mg Capsule
For information purposes only. Consult a doctor before taking any medicine.
Afogatran 110 Capsule
by Torrent Pharmaceuticals Ltd
₹32.2/capsule
54% cheaper
Dabistar 110 Capsule
by Lupin Ltd
₹30.9/capsule
56% cheaper
Dabigat 110 Capsule
by Natco Pharma Ltd
₹31.6/capsule
55% cheaper
Dabiclot 110 Capsule
by Alkem Laboratories Ltd
₹29.3/capsule
58% cheaper
Dablexa 110 Capsule
by Abbott
₹35.2/capsule
49% cheaper
Quick tips
- Take it as per dose and duration suggested by your doctor.
- Pradaxa 110mg Capsule increases your risk of bleeding. Be careful while shaving, cutting fingernails or toenails, using sharp objects or engaging in contact sports (e.g., football and wrestling).
- If you are going to have a surgery or dental treatment, you may be asked to stop taking Pradaxa 110mg Capsule temporarily.
- Your doctor may get a blood test done to check kidney function before starting treatment with this medicine.
- Inform your doctor if you are pregnant, planning pregnancy or breastfeeding.
- Do not stop taking the medication without talking to your doctor.
Safety advice

Alcohol
UNSAFE
It is unsafe to consume alcohol with Pradaxa 110mg Capsule.

Pregnancy
CONSULT YOUR DOCTOR
Pradaxa 110mg Capsule may be unsafe to use during pregnancy. Although there are limited studies in humans, animal studies have shown harmful effects on the developing baby. Your doctor will weigh the benefits and any potential risks before prescribing it to you. Please consult your doctor.

Breast feeding
CONSULT YOUR DOCTOR
Pradaxa 110mg Capsule is probably unsafe to use during breastfeeding. Limited human data suggests that the drug may pass into the breastmilk and harm the baby.

Driving
SAFE
Pradaxa 110mg Capsule does not usually affect your ability to drive.

Kidney
CAUTION
Pradaxa 110mg Capsule should be used with caution in patients with severe kidney disease. Dose adjustment of Pradaxa 110mg Capsule may be needed. Please consult your doctor.
Use of Pradaxa 110mg Capsule is not recommended in patients with severe kidney disease.
Use of Pradaxa 110mg Capsule is not recommended in patients with severe kidney disease.

Liver
CAUTION
Pradaxa 110mg Capsule should be used with caution in patients with liver disease. Dose adjustment of Pradaxa 110mg Capsule may be needed. Please consult your doctor.
Frequently asked questions
Mostly, Pradaxa 110mg Capsule is suggested to be taken twice daily at the same time each day. The two doses should be taken at a gap of about 12 hours.
Taking alcohol while taking Pradaxa 110mg Capsule can increase the effect of this medicine, thereby increasing the chance of bleeding. Regular intake of alcohol can lead to a gastric ulcer which might again cause bleeding. So, it is better to avoid alcohol while you are taking this medicine. Do consult your doctor if any such episode of bleeding occurs.
As compared to other blood-thinning medications, Pradaxa 110mg Capsule does not usually cause hair loss. However, there do exist some rare reports of hair loss associated with Pradaxa 110mg Capsule. Consult your doctor if you face hair loss while taking Pradaxa 110mg Capsule to rule out any other causes of hair loss.
Pradaxa 110mg Capsule reduces your risk of developing blood clots in the blood vessels of your leg, lungs, heart and brain. You may not feel any difference after taking Pradaxa 110mg Capsule. However, keep taking this medicine as prescribed by your doctor because you will still be getting its full benefits.
Unlike other anticoagulants, Pradaxa 110mg Capsule usually does not affect the functioning of the liver. But long-term use of Pradaxa 110mg Capsule may increase the chances of mild liver injury in patients with elevated liver enzymes. However, the overall chances of developing any such problem are lower than other anticoagulants. It is advised that you inform your doctor if you have a history of liver disease before starting this medicine.
Pradaxa 110mg Capsule should be stored at room temperature between 59°F to 86°F (15°C to 30°C). Store the medicine at a dry place and protect the capsules from moisture. Close the bottle tightly after use and keep it out of the reach of children. Once the bottle is opened, it should be used within 4 months. If unused within 4 months, please discard them safely.
Yes, Pradaxa 110mg Capsule increases the risk of bleeding. Always be careful while doing activities that may cause an injury or bleeding. Tell your doctor immediately if you notice any abnormal bruising or bleeding.
People experiencing any unusual bleeding or people allergic to Pradaxa 110mg Capsule should not take it. Pradaxa 110mg Capsule should also be avoided by people with artificial (prosthetic) heart valves. Therefore, inform your doctor if you have ever had or plan to have a valve in your heart replaced.
Fact Box
Chemical Class
Benzimidazole derivative
Habit Forming
No
Therapeutic Class
CARDIAC
Action Class
Direct thrombin inhibitor- oral
References
- Weitz JI. Blood Coagulation and Anticoagulant, Fibrinolytic, and Antiplatelet Drugs. In: Brunton LL, Chabner BA, Knollmann BC, editors. Goodman & Gilman’s: The Pharmacological Basis of Therapeutics. 12th ed. New York, New York: McGraw-Hill Medical; 2011. pp. 865-66.
- Zehnder JL. Drugs Used in Disorders of Coagulation. In: Katzung BG, Masters SB, Trevor AJ, editors. Basic and Clinical Pharmacology. 11th ed. New Delhi, India: Tata McGraw Hill Education Private Limited; 2009. p. 594.
- Briggs GG, Freeman RK, editors. A Reference Guide to Fetal and Neonatal Risk: Drugs in Pregnancy and Lactation. 10th ed. Philadelphia, PA: Wolters Kluwer Health; 2015. pp. 346-47.
- Fox KA, White HD, Gersh BJ, et al. Antithrombotic Agents: Platelete Inhibitors, Acute Anticoagulants, Fibrinolytics, and Chronic Anticoagulants. In: Opie LH, Gersh BJ, editors. Drugs for the Heart. 8th ed. Philadelphia, Pennsylvania: Elsevier Saunders; 2013. pp. 363-65.
- Dabigatran etexilate mesylate. Ridgefield, Connecticut: Boehringer Ingelheim Pharmaceuticals, Inc.; 2010 [revised Nov. 2015]. [Accessed 15 Mar. 2019] (online) Available from:
- Drugs and Lactation Database (LactMed) [Internet]. Bethesda (MD): National Library of Medicine (US); 2006. Dabigatran. [Updated 2020 Jan 20]. [Accessed 19 Feb. 2020] (online) Available from:
- Central Drugs Standard Control Organisation (CDSCO). Dabigatran Etexilate. [Accessed 15 Mar. 2019] (online) Available from:
- Dabigatran Etexilate [Prescribing Information]. Ridgefield, CT: Boehringer Ingelheim Pharmaceuticals, Inc.; 2021. [Accessed 16 Jun. 2023] (online) Available from:

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Patient concerns
Is there any subsitute medicine for PRADAXA 110 mg
Dr. Saurabh Arora
Cardiology
Yes but this is the safe option
Need continued prescription for a year for anti coagulant Pradaxa 110mg , two capsules a day as per attached prescription from Manipal hospital bangalore This prescription renewal is required for purpose of buying medicine online as medicine is advised life long
Dr. Saurabh Arora
Cardiology
Need to consult physician near u can't prescribe online
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