Pradaxa 150mg Capsule

Written By Dr. Betina Chandolia, MDS, BDS

Reviewed By Dr. Lalit Kanodia, MBA, MD Pharmacology

Last updated on 12 Nov 2024 | 01:10 AM (IST)

Pradaxa 150mg Capsule is an anticoagulant or blood thinner. It helps prevent and treat blood clots. It is used to reduce the risk of stroke and heart attack. It prevents and treats clot formation in the veins of your legs, lungs, brain, and heart.

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General Information

Contains

Dabigatran Etexilate (150mg)

Marketer

Boehringer Ingelheim

Storage

Store below 30°C

The content is shown in English

Product introduction

Pradaxa 150mg Capsule is commonly used in patients with irregular heart rhythm (atrial fibrillation) to prevent clot formation. It also reduces the risk of getting clots in people who have undergone knee or hip replacement surgeries. It can be taken with or without food, but it is best to take them at the same time each day. You may need to take this medicine for many years, even for life in some cases. Do not stop taking it or change the dose without guidance from your doctor. It could quickly put you more at risk of having a heart attack, stroke, or thrombosis (formation of a blood clot within a blood vessel). You can reduce your risk of having a blood clot by making changes to your lifestyle, such as not smoking, eating a healthy diet, getting regular exercise, and losing weight if you need to.

The most common side effect of Pradaxa 150mg Capsule are stomach upset and bleeding more easily than normal, for example having nosebleeds or bruising. If you experience any symptoms, tell your doctor immediately. Other side effects include headaches, seizures, allergic reactions, changes to your eyesight, and tiredness.

Do not take this medicine if you have severe kidney or liver problems, if you are currently bleeding or if you are taking other medicines to reduce blood clotting. You should not breastfeed while using this medicine. Unlike other anticoagulants, a regular blood test (PT-INR) is not required while taking this medicine.

Uses of Pradaxa Capsule

Treatment and prevention of Blood clots

Benefits of Pradaxa Capsule

Treatment and prevention of Blood clots
Pradaxa 150mg Capsule is a type of medicine known as an anticoagulant. Although it does not “dissolve” blood clots, it can prevent them from getting bigger so your body can dissolve them over time. It will also prevent new ones from forming. It works by blocking a substance in the body which is involved in blood clotting. This keeps your blood flowing freely around your body and makes it less likely that a clot will form inside a blood vessel. This can help prevent or reduce damage caused by stroke, clots in your lungs (pulmonary embolism), or other blood vessels (thrombosis). It can also make it less likely that parts of a clot will break off and travel to other parts of the body. You should take it regularly and make appropriate lifestyle changes to help this medicine be effective.

Side effects of Pradaxa Capsule

Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them

Common side effects of Pradaxa

Nausea
Anemia (low number of red blood cells)
Gastrointestinal bleeding
Dyspepsia
Diarrhea
Abdominal pain
Nosebleeds
Skin bleeding

How to use Pradaxa Capsule

Take this medicine in the dose and duration as advised by your doctor. Pradaxa 150mg Capsule may be taken with or without food, but it is better to take it at a fixed time.

How Pradaxa Capsule works

Pradaxa 150mg Capsule is a novel oral anticoagulant (NOAC). It works by preventing the formation of blood clots in the body.

All substitutes for Pradaxa 150mg Capsule

For information purposes only. Consult a doctor before taking any medicine.

Quick tips

Take it as per dose and duration suggested by your doctor.
Pradaxa 150mg Capsule increases your risk of bleeding. Be careful while shaving, cutting fingernails or toenails, using sharp objects or engaging in contact sports (e.g., football and wrestling).
If you are going to have a surgery or dental treatment, you may be asked to stop taking Pradaxa 150mg Capsule temporarily.
Your doctor may get a blood test done to check kidney function before starting treatment with this medicine.
Inform your doctor if you are pregnant, planning pregnancy or breastfeeding.
Do not stop taking the medication without talking to your doctor.

Safety advice

Alcohol

UNSAFE

It is unsafe to consume alcohol with Pradaxa 150mg Capsule.

Pregnancy

CONSULT YOUR DOCTOR

Pradaxa 150mg Capsule may be unsafe to use during pregnancy. Although there are limited studies in humans, animal studies have shown harmful effects on the developing baby. Your doctor will weigh the benefits and any potential risks before prescribing it to you. Please consult your doctor.

Breast feeding

CONSULT YOUR DOCTOR

Pradaxa 150mg Capsule is probably unsafe to use during breastfeeding. Limited human data suggests that the drug may pass into the breastmilk and harm the baby.

Driving

SAFE

Pradaxa 150mg Capsule does not usually affect your ability to drive.

Kidney

CAUTION

Pradaxa 150mg Capsule should be used with caution in patients with severe kidney disease. Dose adjustment of Pradaxa 150mg Capsule may be needed. Please consult your doctor.
Use of Pradaxa 150mg Capsule is not recommended in patients with severe kidney disease.

Liver

CAUTION

Pradaxa 150mg Capsule should be used with caution in patients with liver disease. Dose adjustment of Pradaxa 150mg Capsule may be needed. Please consult your doctor.

Frequently asked questions

When should I take Pradaxa 150mg Capsule?

Mostly, Pradaxa 150mg Capsule is suggested to be taken twice daily at the same time each day. The two doses should be taken at a gap of about 12 hours.

Can I drink alcohol with Pradaxa 150mg Capsule?

Taking alcohol while taking Pradaxa 150mg Capsule can increase the effect of this medicine, thereby increasing the chance of bleeding. Regular intake of alcohol can lead to a gastric ulcer which might again cause bleeding. So, it is better to avoid alcohol while you are taking this medicine. Do consult your doctor if any such episode of bleeding occurs.

Can Pradaxa 150mg Capsule cause hair loss?

As compared to other blood-thinning medications, Pradaxa 150mg Capsule does not usually cause hair loss. However, there do exist some rare reports of hair loss associated with Pradaxa 150mg Capsule. Consult your doctor if you face hair loss while taking Pradaxa 150mg Capsule to rule out any other causes of hair loss.

When will I feel better after taking Pradaxa 150mg Capsule?

Pradaxa 150mg Capsule reduces your risk of developing blood clots in the blood vessels of your leg, lungs, heart and brain. You may not feel any difference after taking Pradaxa 150mg Capsule. However, keep taking this medicine as prescribed by your doctor because you will still be getting its full benefits.

Does Pradaxa 150mg Capsule affect the liver?

Unlike other anticoagulants, Pradaxa 150mg Capsule usually does not affect the functioning of the liver. But long-term use of Pradaxa 150mg Capsule may increase the chances of mild liver injury in patients with elevated liver enzymes. However, the overall chances of developing any such problem are lower than other anticoagulants. It is advised that you inform your doctor if you have a history of liver disease before starting this medicine.

How should I store Pradaxa 150mg Capsule?

Pradaxa 150mg Capsule should be stored at room temperature between 59°F to 86°F (15°C to 30°C). Store the medicine at a dry place and protect the capsules from moisture. Close the bottle tightly after use and keep it out of the reach of children. Once the bottle is opened, it should be used within 4 months. If unused within 4 months, please discard them safely.

Can the use of Pradaxa 150mg Capsule increase the risk of bleeding?

Yes, Pradaxa 150mg Capsule increases the risk of bleeding. Always be careful while doing activities that may cause an injury or bleeding. Tell your doctor immediately if you notice any abnormal bruising or bleeding.

Who should not take Pradaxa 150mg Capsule?

People experiencing any unusual bleeding or people allergic to Pradaxa 150mg Capsule should not take it. Pradaxa 150mg Capsule should also be avoided by people with artificial (prosthetic) heart valves. Therefore, inform your doctor if you have ever had or plan to have a valve in your heart replaced.

Fact Box

Chemical Class

Benzimidazole derivative

Habit Forming

Therapeutic Class

CARDIAC

Action Class

Direct thrombin inhibitor- oral

References

Weitz JI. Blood Coagulation and Anticoagulant, Fibrinolytic, and Antiplatelet Drugs. In: Brunton LL, Chabner BA, Knollmann BC, editors. Goodman & Gilman’s: The Pharmacological Basis of Therapeutics. 12th ed. New York, New York: McGraw-Hill Medical; 2011. pp. 865-66.
Zehnder JL. Drugs Used in Disorders of Coagulation. In: Katzung BG, Masters SB, Trevor AJ, editors. Basic and Clinical Pharmacology. 11th ed. New Delhi, India: Tata McGraw Hill Education Private Limited; 2009. p. 594.
Briggs GG, Freeman RK, editors. A Reference Guide to Fetal and Neonatal Risk: Drugs in Pregnancy and Lactation. 10th ed. Philadelphia, PA: Wolters Kluwer Health; 2015. pp. 346-47.
Fox KA, White HD, Gersh BJ, et al. Antithrombotic Agents: Platelete Inhibitors, Acute Anticoagulants, Fibrinolytics, and Chronic Anticoagulants. In: Opie LH, Gersh BJ, editors. Drugs for the Heart. 8th ed. Philadelphia, Pennsylvania: Elsevier Saunders; 2013. pp. 363-65.
Dabigatran etexilate mesylate. Ridgefield, Connecticut: Boehringer Ingelheim Pharmaceuticals, Inc.; 2010 [revised Nov. 2015]. [Accessed 15 Mar. 2019] (online) Available from:
Drugs and Lactation Database (LactMed) [Internet]. Bethesda (MD): National Library of Medicine (US); 2006. Dabigatran. [Updated 2020 Jan 20]. [Accessed 19 Feb. 2020] (online) Available from:
Central Drugs Standard Control Organisation (CDSCO). Dabigatran Etexilate. [Accessed 15 Mar. 2019] (online) Available from:
Dabigatran Etexilate [Prescribing Information]. Ridgefield, CT: Boehringer Ingelheim Pharmaceuticals, Inc.; 2021. [Accessed 16 Jun. 2023] (online) Available from:

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User feedback

Patients taking Pradaxa 150mg Capsule

Twice A Day

88%

Once A Day

11%

What are you using Pradaxa Capsule for?

Deep vein thrombosis

75%

Pulmonary embolism

25%

How much was the improvement?

Excellent

83%

Average

17%

What were the side-effects while using Pradaxa 150mg Capsule?

Gastritis

50%

No Side Effect

50%

Patient concerns

Heavy headache left side only. Two year before I'll take pradaxa 150mg tablets. But now I didn't take that.

Dr. Vikas Sharma

Neurology

Pls upload reports of proper resolution

Is there any subsitute medicine for PRADAXA 110 mg

Dr. Saurabh Arora

Cardiology

Yes but this is the safe option

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Tata 1mg's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover everything about particular health conditions, lab tests, medicines, all possible side effects, drug interactions, warnings, alerts, etc. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.

Marketer details

Name: Boehringer Ingelheim
Address: 1102, Hallmark Business Plaza, 11th Floor, Gurunanak Hospital Road, Near Gurunanak Hospital, Bandra (East), Mumbai 400051

Vendor Details

Country of origin: Germany
A licensed vendor partner from your nearest location will deliver Pradaxa 150mg Capsule. Once the pharmacy accepts your order, the details of the pharmacy will be shared with you. Acceptance of your order is based on the validity of your doctor's ℞ and the availability of this medicine.

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