
Praxis 40mg Injection
Written By Dr. Betina Chandolia, MDS, BDS
Reviewed By Dr. Lalit Kanodia, MBA, MD Pharmacology
Last updated on 25 Oct 2024 | 01:09 AM (IST)
Praxis 40mg Injection is a pain-relieving medicine. It is used for short-term treatment of postoperative pain. It is given in cases where oral administration of pain killers is unsuitable. It provides only temporary relief and does not cure the condition.
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Product introduction
Praxis 40mg Injection is generally administered by a healthcare professional. The dose and duration will depend on what you are taking it for and how well it helps your symptoms. You should keep receiving the medicine until the doctor says it is okay to stop using the medicine.
The most common side effect of this medicine is nausea. You may also experience other side effects like changes in blood pressure, back pain, fluid retention, numbness, vomiting, stomach ache, indigestion, constipation, and bloating among others. If any of these side effects persist or get worse, you should let your doctor know.
Before taking it, you should let your doctor know if you have a history of stomach ulcers, heart diseases, high blood pressure, and liver or kidney disease. Let your doctor also know about all the other medicines you are taking because they may affect, or be affected by, this medicine.
This medicine is not recommended for pregnant or breastfeeding women. Pregnant and breastfeeding mothers must consult with their doctors before using the medicine.
The most common side effect of this medicine is nausea. You may also experience other side effects like changes in blood pressure, back pain, fluid retention, numbness, vomiting, stomach ache, indigestion, constipation, and bloating among others. If any of these side effects persist or get worse, you should let your doctor know.
Before taking it, you should let your doctor know if you have a history of stomach ulcers, heart diseases, high blood pressure, and liver or kidney disease. Let your doctor also know about all the other medicines you are taking because they may affect, or be affected by, this medicine.
This medicine is not recommended for pregnant or breastfeeding women. Pregnant and breastfeeding mothers must consult with their doctors before using the medicine.
Uses of Praxis Injection
Benefits of Praxis Injection
Pain relief
Praxis 40mg Injection is used for short term relief of pain in cases where it is not possible to take a pain killer by mouth like in the case of surgery. It works by blocking chemical messengers in the brain that tell us we have pain.
It is given as an injection by a doctor or nurse and should not be self-administered. The dose and duration will be decided by the doctor depending on the condition you are being treated for. This will help you to go about your daily activities more easily and have a better, more active, quality of life.
Praxis 40mg Injection is used for short term relief of pain in cases where it is not possible to take a pain killer by mouth like in the case of surgery. It works by blocking chemical messengers in the brain that tell us we have pain.
It is given as an injection by a doctor or nurse and should not be self-administered. The dose and duration will be decided by the doctor depending on the condition you are being treated for. This will help you to go about your daily activities more easily and have a better, more active, quality of life.
Side effects of Praxis Injection
Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them
Common side effects of Praxis
- Nausea
- Change in blood pressure
- Back pain
- Numbness
- Constipation
- Indigestion
- Stomach pain
- Vomiting
- Bloating
How to use Praxis Injection
Your doctor or nurse will give you this medicine. Kindly do not self administer.
How Praxis Injection works
Praxis 40mg Injection is a non-steroidal anti-inflammatory drug (NSAID) called COX-2 inhibitors. It works by blocking the release of certain chemical messengers that are responsible for pain and inflammation (redness and swelling).
Quick tips
- Praxis 40mg Injection helps relieve pain and inflammation.
- It may cause fewer stomach problems as compared to other NSAIDs like Ibuprofen or Naproxen.
- It may cause dizziness and fatigue. Do not drive or do anything requiring concentration until you know how it affects you.
- Do not consume alcohol while on treatment with this medicine as it may cause excessive drowsiness.
- Regularly monitor your blood pressure while taking this medicine, particularly in the first two weeks after starting treatment.
- Inform your doctor if you have a history of stomach ulcers, heart diseases, high blood pressure, and liver or kidney disease.
- During long-term treatment, your doctor may want to take regular blood tests to monitor your liver function.
- Do not take Praxis 40mg Injection if you are pregnant, planning to conceive, or breastfeeding.
Safety advice

Alcohol
CAUTION
Caution is advised when consuming alcohol with Praxis 40mg Injection. Please consult your doctor.

Pregnancy
CONSULT YOUR DOCTOR
Praxis 40mg Injection may be unsafe to use during pregnancy. Although there are limited studies in humans, animal studies have shown harmful effects on the developing baby. Your doctor will weigh the benefits and any potential risks before prescribing it to you. Please consult your doctor.

Breast feeding
CONSULT YOUR DOCTOR
Information regarding the use of Praxis 40mg Injection during breastfeeding is not available. Please consult your doctor.

Driving
UNSAFE
Praxis 40mg Injection may decrease alertness, affect your vision or make you feel sleepy and dizzy. Do not drive if these symptoms occur.

Kidney
CAUTION
Praxis 40mg Injection should be used with caution in patients with severe kidney disease. Dose adjustment of Praxis 40mg Injection may be needed. Please consult your doctor.

Liver
CAUTION
Praxis 40mg Injection should be used with caution in patients with liver disease. Dose adjustment of Praxis 40mg Injection may be needed. Please consult your doctor.
Use of Praxis 40mg Injection is not recommended in patients with severe liver disease.
Use of Praxis 40mg Injection is not recommended in patients with severe liver disease.
Frequently asked questions
Praxis 40mg Injection is used in adults for short term treatment of pain after surgery
Praxis 40mg Injection belongs to class of medications called cyclo-oxygenase-2 (COX-2) inhibitors. It works by inhibiting the enzyme COX-2 that reduces the formation of chemicals called prostaglandins in the body, thereby reducing pain and inflammation.
Fact Box
Chemical Class
Benzenesulfonamides Derivative
Habit Forming
No
Therapeutic Class
PAIN ANALGESICS
Action Class
NSAID's -Selective COX-2 Inhibitors
References
- Grosser T, Smyth E, FitzGerald GA. Anti-Inflammatory, Antipyretic, and Analgesic Agents; Pharmacotherapy of Gout. In: Brunton LL, Chabner BA, Knollmann BC, editors. Goodman & Gilman’s: The Pharmacological Basis of Therapeutics. 12th ed. New York, New York: McGraw-Hill Medical; 2011. pp. 991-92.
- Central Drugs Standard Control Organisation (CDSCO). [Accessed 02 Apr. 2019] (online) Available from:
- Parecoxib [Package leaflet: Information for the user]. Kent, UK: Pfizer Limited; 2020. [Accessed 17 Dec. 2020] (online) Available from:
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