Premagan Injection
Written By Dr. Betina Chandolia, MDS, BDS
Reviewed By Dr. Lalit Kanodia, MBA, MD Pharmacology
Last updated on 11 Nov 2024 | 01:03 AM (IST)
Premagan Injection is used to treat nausea and vomiting associated with motion sickness, or maybe before and after any surgery. It is also used in combination with other medicines to treat severe allergic reactions (anaphylaxis).
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General Information
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Product introduction
Premagan Injection is given as an injection under the supervision of healthcare professionals. It should be taken as your doctor's advice. The dose and how often you take it depends on what you are taking it for. Your doctor will decide how much you need to improve your symptoms. You should take this medicine for as long as it is prescribed for you. You must inform your doctor if symptoms do not improve within 7 days of the treatment.
The most common side effects of this medicine include dry mouth, blur vision, headache, and feeling dizzy. If these bother you or appear serious, let your doctor know. There may be ways of reducing or preventing them. It makes the skin more sensitive towards sunlight. use sunscreen or wear protective clothing before going out.
Before taking this medicine, let your doctor know if you have glaucoma or have asthma issues, or have high blood pressure. Inform your doctor if you are pregnant, or breastfeeding. Your doctor should also know about all other medicines you are taking as many of these may make this medicine less effective or change the way it works. Generally, it is advised to avoid alcohol while on treatment.
The most common side effects of this medicine include dry mouth, blur vision, headache, and feeling dizzy. If these bother you or appear serious, let your doctor know. There may be ways of reducing or preventing them. It makes the skin more sensitive towards sunlight. use sunscreen or wear protective clothing before going out.
Before taking this medicine, let your doctor know if you have glaucoma or have asthma issues, or have high blood pressure. Inform your doctor if you are pregnant, or breastfeeding. Your doctor should also know about all other medicines you are taking as many of these may make this medicine less effective or change the way it works. Generally, it is advised to avoid alcohol while on treatment.
Uses of Premagan Injection
Benefits of Premagan Injection
Treatment of Severe allergic reactions
Premagan Injection is used to treat many different inflammatory and allergic conditions. It works by lowering your immune system’s response to these conditions and prevents the release of substances in the body that cause inflammation. It helps relieve symptoms such as swelling, pain, itching, and other allergic-type reactions. If you are not sure why you are being given this medicine, ask your doctor.
It is given as an injection by a doctor or nurse and should not be self-administered. Taking this medicine enables you to live your life more freely without worrying so much about things that set off your symptoms. Because this medicine weakens your immune system, you should avoid being near people who are ill or have infections.
Premagan Injection is used to treat many different inflammatory and allergic conditions. It works by lowering your immune system’s response to these conditions and prevents the release of substances in the body that cause inflammation. It helps relieve symptoms such as swelling, pain, itching, and other allergic-type reactions. If you are not sure why you are being given this medicine, ask your doctor.
It is given as an injection by a doctor or nurse and should not be self-administered. Taking this medicine enables you to live your life more freely without worrying so much about things that set off your symptoms. Because this medicine weakens your immune system, you should avoid being near people who are ill or have infections.
Treatment of Nausea
Premagan Injection blocks the action of chemicals in the body that can make you feel or be sick. It is often used to prevent nausea and vomiting that may be caused due to some medicines or any other medical treatment. This medicine helps you recover more comfortably. The dose will depend on what you are being treated for but always take this medicine as it is prescribed.
Premagan Injection blocks the action of chemicals in the body that can make you feel or be sick. It is often used to prevent nausea and vomiting that may be caused due to some medicines or any other medical treatment. This medicine helps you recover more comfortably. The dose will depend on what you are being treated for but always take this medicine as it is prescribed.
Treatment of Allergic conditions
Premagan Injection is used to treat many different inflammatory and allergic conditions. It works by lowering your immune system’s response to these conditions and prevents the release of substances in the body that cause inflammation. It helps relieve symptoms such as swelling, pain, itching, and other allergic-type reactions. If you are not sure why you are being given this medicine, ask your doctor.
This medicine is given orally (by mouth). You should always take it as it has been prescribed for you. Do not stop taking it without your doctor’s advice. This can cause unpleasant withdrawal symptoms. Because this medicine weakens your immune system, you should avoid being near people who are ill or have infections.
Premagan Injection is used to treat many different inflammatory and allergic conditions. It works by lowering your immune system’s response to these conditions and prevents the release of substances in the body that cause inflammation. It helps relieve symptoms such as swelling, pain, itching, and other allergic-type reactions. If you are not sure why you are being given this medicine, ask your doctor.
This medicine is given orally (by mouth). You should always take it as it has been prescribed for you. Do not stop taking it without your doctor’s advice. This can cause unpleasant withdrawal symptoms. Because this medicine weakens your immune system, you should avoid being near people who are ill or have infections.
Treatment of Motion sickness
Motion sickness is a condition caused due to motion during travel. You may experience spinning sensation (vertigo), nausea or vomiting as a result of this condition. Premagan Injection helps treat these symptoms effectively. Take it as prescribed by the doctor to get maximum benefit.
Motion sickness is a condition caused due to motion during travel. You may experience spinning sensation (vertigo), nausea or vomiting as a result of this condition. Premagan Injection helps treat these symptoms effectively. Take it as prescribed by the doctor to get maximum benefit.
How to use Premagan Injection
Your doctor or nurse will give you this medicine. Kindly do not self administer.
How Premagan Injection works
Premagan Injection is an antiallergic medication. When your body is exposed to an allergen (pollen, animal dander, house dust etc.), it produces a chemical called histamine. This causes watery eyes, runny or blocked nose, sneezing, skin rashes, itching etc. Premagan Injection works by blocking the action of histamine, thereby relieving these symptoms. It also works directly on several areas of the brain to prevent nausea/vomiting and help you feel more relaxed.
Quick tips
- Premagan Injection helps treat nausea, vomiting and allergic conditions.
- Use caution while driving or doing anything that requires concentration as Premagan Injection can cause dizziness and sleepiness.
- Do not drink alcohol while taking this medication as it may cause increased sleepiness.
- It may make your skin more sensitive to sunlight. Avoid exposing your skin to strong sunlight, use a sunscreen lotion or make sure your skin is protected with clothing.
- Do not take it for longer than 7 days. If your symptoms worsen or do not improve after 7 days, talk to your doctor.
- Stop taking it at least three days before taking an allergy test as it can affect the test results.
Safety advice

Alcohol
UNSAFE
Premagan Injection may cause excessive drowsiness with alcohol.

Pregnancy
CONSULT YOUR DOCTOR
Premagan Injection may be unsafe to use during pregnancy. Although there are limited studies in humans, animal studies have shown harmful effects on the developing baby. Your doctor will weigh the benefits and any potential risks before prescribing it to you. Please consult your doctor.

Breast feeding
SAFE IF PRESCRIBED
Premagan Injection is probably safe to use during breastfeeding. Limited human data suggests that the drug does not represent any significant risk to the baby.
For prolonged use and repeated doses of Premagan Injection, observe the baby for excessive sleepiness.
For prolonged use and repeated doses of Premagan Injection, observe the baby for excessive sleepiness.

Driving
UNSAFE
Premagan Injection may decrease alertness, affect your vision or make you feel sleepy and dizzy. Do not drive if these symptoms occur.

Kidney
SAFE IF PRESCRIBED
Premagan Injection is probably safe to use in patients with kidney disease. Limited data available suggests that dose adjustment of Premagan Injection may not be needed in these patients. Please consult your doctor.
However, caution is advised in patients with severe kidney disease as it may cause excessive sleepiness in them.
However, caution is advised in patients with severe kidney disease as it may cause excessive sleepiness in them.

Liver
CAUTION
Premagan Injection should be used with caution in patients with liver disease. Dose adjustment of Premagan Injection may be needed. Please consult your doctor.

Frequently asked questions
Premagan Injection is antihistaminic drug and not a narcotic/opiate/pain killer. Patient should follow the advice of doctor regarding its use
No, it is available with doctor's prescription only
Premagan Injection is used for treatment of symptoms of allergies, but not used for hangover, sore throat, stomach flu, cramps, toothache, headache and cough. Patient should follow the advice of doctor regarding its use
Yes, but taking other medicines may alter the effects of Premagan Injection. Always consult your doctor for the change of dose regimen or an alternative drug of choice that may strictly be required
Premagan Injection may cause these side effects which are not serious. However, always consult your doctor if you experience any of these side effects.
Fact Box
Chemical Class
Phenothiazine Derivative
Habit Forming
No
Therapeutic Class
GASTRO INTESTINAL
Action Class
H1 Antihistaminics (First Generation)
Related lab tests
References
- Briggs GG, Freeman RK, editors. A Reference Guide to Fetal and Neonatal Risk: Drugs in Pregnancy and Lactation. 10th ed. Philadelphia, PA: Wolters Kluwer Health; 2015. pp. 1159-60.
- Promethazine. Guildford, Surrey: SANOFI; 2002 [revised 17 Aug. 2016] (online) Available from:
- Chaves RG, Lamounier JA. Breastfeeding and maternal medications. J Pediatr (Rio J). 2004;80(5 Suppl):S189-S198. [Accessed 01 Apr. 2019] (online) Available from:

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Tata 1mg's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover everything about particular health conditions, lab tests, medicines, all possible side effects, drug interactions, warnings, alerts, etc. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.
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Name: Shine Pharmaceuticals Ltd
Address: 308-310 Dwarkesh Complex, Sun Pharma Road, Po:Atladra, Vadodara-390 012., Gujarat, India.
Address: 308-310 Dwarkesh Complex, Sun Pharma Road, Po:Atladra, Vadodara-390 012., Gujarat, India.
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Country of origin: India
Lab tests offered by us
- CBC (Complete Blood Count)
- FBS (Fasting Blood Sugar)
- Thyroid Profile Total (T3, T4 & TSH)
- HbA1c (Glycosylated Hemoglobin)
- Glucose - Postprandial
- Lipid Profile
- Vitamin D (25-Hydroxy)
- Urine R/M (Urine Routine & Microscopy)
- Coronavirus Covid-19 Test (RT-PCR technique)
- LFT (Liver Function Test)
- Kidney Function Test
- TSH (Thyroid Stimulating Hormone) Ultrasensitive
- ESR (Erythrocyte Sedimentation Rate)
- Uric Acid
- Vitamin B12
- C- Reactive Protein Quantitative
- Urine Culture and Sensitivity
- Serum Electrolyte
- Serum Calcium
- Creatinine
- Diabetes Screening
- KFT with Electrolytes (Kidney Function Test with Electrolytes)
- Cholesterol - Total
- Hemoglobin
- Complete Haemogram
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