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Quel 400mg Tablet SR

Written By Dr. Swati Mishra, BDS
Reviewed By Dr. Varun Gupta, MD Pharmacology, MBBS
Last updated on 08 Nov 2024 | 01:10 AM (IST)
Quel 400mg Tablet SR is used in the treatment of schizophrenia (a mental disorder that can result in hallucinations or delusions and also adversely affects a person’s ability to think and behave) and mania. It is also used to treat bipolar disorders.
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General Information

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Product introduction

Quel 400mg Tablet SR may be taken with or without food. However, it is advised to take it at the same time each day as this helps to maintain a consistent level of medicine in the body. Take this in the dose and duration as advised by your doctor and if you have missed a dose, take it as soon as you remember. It is important that this medication is not stopped suddenly without talking to your doctor as it may worsen your symptoms. However, discontinue this medicine immediately if you experience Neuroleptic malignant syndrome (NMS), characterized by fever, muscle rigidity, and altered consciousness or seizures.

Some common side effects of this medicine include decreased hemoglobin levels in the blood, increased triglycerides level in blood, decreased cholesterol level in blood, headache, extrapyramidal symptoms, dry mouth, and withdrawal symptoms. Initially, this medicine may cause a sudden drop in blood pressure when you change positions, so it is better to rise slowly if you have been sitting or lying down. It also causes dizziness and sleepiness, so do not drive or do anything that requires mental focus until you know how this medicine affects you. This medicine may increase your weight but, modifying your lifestyle by having a healthy diet and exercising regularly can reduce this side effect.

You should be cautious while using this medicine as it may increase the risk of developing diabetes, so it is better to monitor glucose regularly. Inform your doctor if you develop any unusual changes in mood or behavior, new or worsening depression, or suicidal thoughts while taking this medicine.

Benefits of Quel Tablet SR

Treatment of Mania
Mania means extremely excited or elevated mood. Quel 400mg Tablet SR helps calm the mood and relax the nerves. This stabilises the mood and prevents the symptoms of mania from recurring again. Taking Quel 400mg Tablet SR will ensure that you have a better social life and are able to do daily activities more comfortably.
Treatment of Schizophrenia
Schizophrenia is a mental disorder in which a person’s thinking ability, feelings and behavior become abnormal. Quel 400mg Tablet SR helps restore the chemical imbalances in the brain that are responsible for such changes. It improves thoughts, behavior and enhances the quality of life.

Side effects of Quel Tablet SR

Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them
Common side effects of Quel
  • Weight gain
  • Constipation
  • Dizziness
  • Dryness in mouth
  • Fatigue
  • High blood pressure
  • Orthostatic hypotension (sudden lowering of blood pressure on standing)
  • Sleepiness
  • Dyslipidemia
  • Increased appetite

How to use Quel Tablet SR

Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Quel 400mg Tablet SR may be taken with or without food, but it is better to take it at a fixed time.

How Quel Tablet SR works

Quel 400mg Tablet SR is an atypical antipsychotic. It works by modulating the action of certain chemical messengers in the brain that affect thoughts.

Quick tips

  • You have been prescribed Quel 400mg Tablet SR for the treatment of schizophrenia and mania.
  • It is less likely to cause heart problems and movement disorders than other antipsychotics.
  • It may take 4 to 6 weeks to see treatment effects. Keep taking it as prescribed.
  • Use caution while driving or doing anything that requires concentration as Quel 400mg Tablet SR can cause dizziness and sleepiness.
  • To lower the chance of feeling dizzy or passing out, rise slowly if you have been sitting or lying down.
  • It may increase your weight, blood sugar and cholesterol. Eat healthy, exercise regularly and monitor your blood levels regularly.
  • Inform your doctor if you develop any unusual changes in mood or behavior, new or worsening depression, or suicidal thoughts or behavior.
  • Do not stop taking it without talking to your doctor first as it may cause worsening of symptoms.

Safety advice

Alcohol

Alcohol

UNSAFE
It is unsafe to consume alcohol with Quel 400mg Tablet SR.
Pregnancy

Pregnancy

CONSULT YOUR DOCTOR
Quel 400mg Tablet SR may be unsafe to use during pregnancy. Although there are limited studies in humans, animal studies have shown harmful effects on the developing baby. Your doctor will weigh the benefits and any potential risks before prescribing it to you. Please consult your doctor.
Breast feeding

Breast feeding

CONSULT YOUR DOCTOR
Quel 400mg Tablet SR is probably unsafe to use during breastfeeding. Limited human data suggests that the drug may pass into the breastmilk and harm the baby.
Driving

Driving

UNSAFE
Quel 400mg Tablet SR may decrease alertness, affect your vision or make you feel sleepy and dizzy. Do not drive if these symptoms occur.
Kidney

Kidney

SAFE IF PRESCRIBED
Quel 400mg Tablet SR is probably safe to use in patients with kidney disease. Limited data available suggests that dose adjustment of Quel 400mg Tablet SR may not be needed in these patients. Please consult your doctor.
Liver

Liver

CAUTION
Quel 400mg Tablet SR should be used with caution in patients with liver disease. Dose adjustment of Quel 400mg Tablet SR may be needed. Please consult your doctor.
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Frequently asked questions

Quel 400mg Tablet SR helps to correct chemical imbalances in the brain. It acts on various chemical messengers in the brain like dopamine and serotonin. It prevents the excessive activity of dopamine, helping to treat symptoms of schizophrenia and mania.
Quel 400mg Tablet SR can make you feel sleepy, but it is not used as a sleeping pill. Quel 400mg Tablet SR is approved for the treatment of symptoms of schizophrenia. It prevents as well as treats episodes of mania and depression in bipolar disorder. It is also used with other medicines to treat depression.
You may start seeing an improvement within a week of starting Quel 400mg Tablet SR but full benefits may take about 4-6 weeks to appear.
Quel 400mg Tablet SR has not been approved for the treatment of anxiety; however, your doctor may prescribe it for anxiety. Some studies suggest its use in post-traumatic stress disorder, generalized anxiety disorder, and anxiety associated with mood disorders.
Quel 400mg Tablet SR can cause drowsiness. So, do not drive, operate machinery or do anything dangerous until you know how Quel 400mg Tablet SR affects you. Do not drink alcohol while taking Quel 400mg Tablet SR as it may worsen the drowsiness. Avoid getting dehydrated or over-exposure to heat.
No, you should not stop taking Quel 400mg Tablet SR without consulting your doctor. Suddenly stopping it may cause nausea, vomiting, headache, diarrhea, dizziness, irritability and inability to sleep. If you feel better, consult your doctor who will gradually reduce the dose before completely stopping it.
Yes, weight gain is a common side effect of Quel 400mg Tablet SR. If you feel you are gaining weight, consult your doctor or a nutritionist who will suggest you a diet and some exercise to help you manage your weight.
Take Quel 400mg Tablet SR exactly as advised by your doctor. Do not split, chew or crush the tablets. Swallow the tablet whole with a glass of water. Do not take it with food. It is advised to take this medicine for at least one hour before a meal or at bedtime. Do not take grapefruit while taking Quel 400mg Tablet SR as it may affect the working of this medicine.

Fact Box

Chemical Class

Dibenzothiazepine Derivatives

Habit Forming

No

Therapeutic Class

NEURO CNS

Action Class

Atypical Antipsychotics

References

  1. Stahl SM, editor. Quetiapine. In: Stahl's Essential Pschopharmacology: Prescriber's Guide. 5th ed. New York, New York: Cambridge University Press; 2014. pp. 575-81.
  2. Briggs GG, Freeman RK, editors. A Reference Guide to Fetal and Neonatal Risk: Drugs in Pregnancy and Lactation. 10th ed. Philadelphia, PA: Wolters Kluwer Health; 2015. pp. 1181-84.
  3. Drugs and Lactation Database (LactMed) [Internet]. Bethesda (MD): National Library of Medicine (US); 2006. Quetiapine. [Updated 2018 Oct 31]. [Accessed 20 Feb. 2020] (online) Available from:
  4. Central Drugs Standard Control Organisation (CDSCO). [Accessed 22 Mar. 2019] (online) Available from:
  5. Quetiapine fumarate [Prescribing Information]. Wilmington, DE: AstraZeneca Pharmaceuticals LP; 2013. [Accessed 20 Feb. 2024] (online) Available from:
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Patient concerns

I am using s vocita and quel sr 50 and migoset for depression and migraine for last 4 months. How can i quit these medicines Can these medicines be discontinued at one go

Dr. Ambrish Dharmadhikari
Dr. Ambrish Dharmadhikari
Psychiatry
We understand your concernWe are here to helpIt is not advisable to stop medications at one goConsult your doctor to gradually reduce dose and stop it eventually

My sister is on medication for schizophrenia since 2005 under Dr. K.K.Sinha of Ranchi. The medicines were stopped in April 2013 However problem reoccurred 4 months later. She was given Quel 200, Joykem 200 and Kamiyan 100. Quel was dropped 6 months later. Power of Joykem and Kamiyan were reduced slowly. For the last 1 year she is taking Prati CR 12.5 as the problem was diminished. But the problem has surfaced again with full severity. Doctor has given date after 2 months. What should be done for the period ? Name of the medicines has been wrongly typed. It's Lamosyn , not Kamiyan. And it's pexti , nor Prati.

Dr. Jyoti Kapoor Madan
Dr. Jyoti Kapoor Madan
Psychiatry
If the patient isn't improving, see your doctor again.
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Disclaimer

Tata 1mg's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover everything about particular health conditions, lab tests, medicines, all possible side effects, drug interactions, warnings, alerts, etc. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.

Marketer details

Name: Ipca Laboratories Ltd
Address: 142 AB, Kandivli Industrial Estate, Kandivli (West), Mumbai - 400 067, Maharashtra

Vendor Details

Country of origin: India
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