Rasburnat Injection
Written By Dr. Sakshi Jain, MS, BDS
Reviewed By Dr. Varun Gupta, MD Pharmacology, MBBS
Last updated on 12 Nov 2024 | 01:08 AM (IST)
Rasburnat Injection is used in the treatment of high uric acid due to chemotherapy. It lowers uric acid levels in the blood which helps prevent kidney damage in cancer patients.
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General Information
Contains
Rasburicase (1.5mg)
Marketer
Natco Pharma Ltd
Storage
Store in a refrigerator (2 - 8°C). Do not freeze.
The content is shown in English


Product introduction
It is given as a slow injection into veins by a doctor or a nurse. Your doctor will decide what dose is necessary and how often you need to take it. This will depend on what you are being treated for and may change from time to time. You should take it exactly as your doctor has advised. Taking it in the wrong way or taking too much can cause very serious side effects. It may take several weeks or months for you to see or feel the benefits but do not stop taking it unless your doctor tells you to.
The most common side effects of this medicine include nausea, headache, vomiting, and rash. However, some side effects require immediate action, hence inform your doctor if you experience difficulty in breathing, chest pain, swelling in the face and throat, itching, or dizziness after taking this medicine. Your doctor may get regular blood tests to check the levels of uric acid during treatment with this medicine. It is better to take plenty of fluids to avoid dehydration.
Many other medicines can affect, or be affected by, this medicine so let your doctor know about all the medications you are using. Let your doctor also know if you have any preexisting medical conditions to make sure this medicine is safe for you.
The most common side effects of this medicine include nausea, headache, vomiting, and rash. However, some side effects require immediate action, hence inform your doctor if you experience difficulty in breathing, chest pain, swelling in the face and throat, itching, or dizziness after taking this medicine. Your doctor may get regular blood tests to check the levels of uric acid during treatment with this medicine. It is better to take plenty of fluids to avoid dehydration.
Many other medicines can affect, or be affected by, this medicine so let your doctor know about all the medications you are using. Let your doctor also know if you have any preexisting medical conditions to make sure this medicine is safe for you.
Uses of Rasburnat Injection
- Treatment of High uric acid due to chemotherapy
Benefits of Rasburnat Injection
Treatment of High uric acid due to chemotherapy
Certain types of cancer, like kidney or bladder cancer, may cause high levels of uric acid due to ongoing cancer chemotherapy. This can worsen patient health conditions and also lead to more serious health issues. Rasburnat Injection helps reduce these high levels of uric acid and prevents further complications. This will ensure speedy recovery and improve your quality of life. Follow your doctor’s instructions and let your doctor know if you have any concerns.
Certain types of cancer, like kidney or bladder cancer, may cause high levels of uric acid due to ongoing cancer chemotherapy. This can worsen patient health conditions and also lead to more serious health issues. Rasburnat Injection helps reduce these high levels of uric acid and prevents further complications. This will ensure speedy recovery and improve your quality of life. Follow your doctor’s instructions and let your doctor know if you have any concerns.
Side effects of Rasburnat Injection
Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them
Common side effects of Rasburnat
- Nausea
- Headache
- Vomiting
- Rash
- Hives
- Fever
- Diarrhea
How to use Rasburnat Injection
Your doctor or nurse will give you this medicine. Kindly do not self administer.
How Rasburnat Injection works
Rasburnat Injection works by causing a reaction with an enzyme that turns uric acid into an inactive substance (allantoin) thereby reducing uric acid levels.
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For information purposes only. Consult a doctor before taking any medicine.
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Quick tips
- Rasburnat Injection lowers uric acid levels in the blood which helps prevent kidney damage in cancer patients.
- It is injected slowly into a vein.
- It is given once a day, for up to 7 days.
- Your doctor may get regular blood tests doneto check the levels of uric acid during treatment with this medicine.
- Inform your doctor immediately if you experience difficulty breathing, chest pain, swelling in the face and throat, itching, or dizziness.
Safety advice

Alcohol
CONSULT YOUR DOCTOR
It is not known whether it is safe to consume alcohol with Rasburnat Injection. Please consult your doctor.

Pregnancy
CONSULT YOUR DOCTOR
Rasburnat Injection may be unsafe to use during pregnancy. Although there are limited studies in humans, animal studies have shown harmful effects on the developing baby. Your doctor will weigh the benefits and any potential risks before prescribing it to you. Please consult your doctor.

Breast feeding
SAFE IF PRESCRIBED
Rasburnat Injection is probably safe to use during breastfeeding. Limited human data suggests that the drug does not represent any significant risk to the baby.

Driving
CONSULT YOUR DOCTOR
It is not known whether Rasburnat Injection alters the ability to drive. Do not drive if you experience any symptoms that affect your ability to concentrate and react.

Kidney
SAFE IF PRESCRIBED
Rasburnat Injection is probably safe to use in patients with kidney disease. Limited data available suggests that dose adjustment of Rasburnat Injection may not be needed in these patients. Please consult your doctor.

Liver
SAFE IF PRESCRIBED
Rasburnat Injection is probably safe to use in patients with liver disease. Limited data available suggests that dose adjustment of Rasburnat Injection may not be needed in these patients. Please consult your doctor.

Fact Box
Chemical Class
Recombinant Xanthine Oxidase Enzyme
Habit Forming
No
Therapeutic Class
BLOOD RELATED
Action Class
Uricolytic agent- Chemotherapy
References
- Grosser T, Smyth E, FitzGerald GA. Anti-Inflammatory, Antipyretic, and Analgesic Agents; Pharmacotherapy of Gout. In: Brunton LL, Chabner BA, Knollmann BC, editors. Goodman & Gilman’s: The Pharmacological Basis of Therapeutics. 12th ed. New York, New York: McGraw-Hill Medical; 2011. p. 998.
- Briggs GG, Freeman RK, editors. A Reference Guide to Fetal and Neonatal Risk: Drugs in Pregnancy and Lactation. 10th ed. Philadelphia, PA: Wolters Kluwer Health; 2015. pp. 1201-202.
- Rasburicase. Guildford, Surrey: SANOFI; 2001 [revised 07 Jul. 2016]. [Accessed 25 Jan. 2019] (online) Available from:
- Drugs and Lactation Database (LactMed) [Internet]. Bethesda (MD): National Library of Medicine (US); 2006. Rasburicase. [Updated 2018 Dec 3]. [Accessed 18 Feb. 2020] (online) Available from:

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Patient concerns
Due to high uric acid level lower leg Joint pain.
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Tab Nucoxia P 1 BD after meals, Cap Pantop DSR 1 BD before meals, Tab FBX 40 mg 1 daily for 10 days.
High uric acid due to which suffering pain under the feet
Dr. Vipul Aggarwal
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More fluids/less fructose (sweet drinks)/ less carbohydrates/ more vegetable protien/ high amount of vitamin c/ less red meat and alcohol / less tea and coffee will help you.
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Tata 1mg's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover everything about particular health conditions, lab tests, medicines, all possible side effects, drug interactions, warnings, alerts, etc. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.
Marketer details
Name: Natco Pharma Ltd
Address: Natco House, Road No.2, Banjara Hills, Hyderabad-500 034, India
Address: Natco House, Road No.2, Banjara Hills, Hyderabad-500 034, India
Vendor Details
Country of origin: India
A licensed vendor partner from your nearest location will deliver Rasburnat Injection. Once the pharmacy accepts your order, the details of the pharmacy will be shared with you. Acceptance of your order is based on the validity of your doctor's ℞ and the availability of this medicine.
Phone Number: 0124-4166666
Address: 5th Floor Tower - B of the Presidency Building, 46/4 Mehrauli Gurgaon Road, Sector 14, Gurugram, Haryana-122001, India
A licensed vendor partner from your nearest location will deliver Rasburnat Injection. Once the pharmacy accepts your order, the details of the pharmacy will be shared with you. Acceptance of your order is based on the validity of your doctor's ℞ and the availability of this medicine.
In case of any issues, contact us
Email ID: [email protected]Phone Number: 0124-4166666
Address: 5th Floor Tower - B of the Presidency Building, 46/4 Mehrauli Gurgaon Road, Sector 14, Gurugram, Haryana-122001, India
Lab tests offered by us
- CBC (Complete Blood Count)
- FBS (Fasting Blood Sugar)
- Thyroid Profile Total (T3, T4 & TSH)
- HbA1c (Glycosylated Hemoglobin)
- Glucose - Postprandial
- Lipid Profile
- Vitamin D (25-Hydroxy)
- Urine R/M (Urine Routine & Microscopy)
- Coronavirus Covid-19 Test (RT-PCR technique)
- LFT (Liver Function Test)
- Kidney Function Test
- TSH (Thyroid Stimulating Hormone) Ultrasensitive
- ESR (Erythrocyte Sedimentation Rate)
- Uric Acid
- Vitamin B12
- C- Reactive Protein Quantitative
- Urine Culture and Sensitivity
- Serum Electrolyte
- Serum Calcium
- Creatinine
- Diabetes Screening
- KFT with Electrolytes (Kidney Function Test with Electrolytes)
- Cholesterol - Total
- Hemoglobin
- Complete Haemogram
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