Reliseal Kit
Written By Dr. Betina Chandolia, MDS, BDS
Reviewed By Dr. Lalit Kanodia, MBA, MD Pharmacology
Last updated on 12 Nov 2024 | 01:02 AM (IST)
Reliseal Kit is a combination medicine used to prevent bleeding in a variety of surgical procedures. It works by preventing the breakdown of clots and control excessive bleeding. It also helps in healing wounds.
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General Information
Contains
Aprotinin (3000KIU)+ Fibrinogen (70mg)+ Thrombin (500IU)
Marketer
Reliance Formulation Pvt Ltd
Storage
Store in a refrigerator (2 - 8°C). Do not freeze.
The content is shown in English


Product introduction
Reliseal Kit is to be administered by a doctor or a nurse in a clinical setting of a hospital. Do not self administer this medicine at home. The dose and duration of the medicine will depend on the severity of your condition. Make sure to get the complete dose of the medicine for full benefit.
Some common side effects of this medicine include fever, headache, increased heart rate, anemia, low blood platelets, pleuritis, asthma, pneumonia, acute kidney failure, nausea, vomiting, dizziness, constipation, and allergy. Let your doctor know if any of these side effects do not go away on their own or get worse.
Before receiving this medicine, let your doctor know if you have any bleeding disorders or are on any blood-thinning medications. Pregnant or breastfeeding women should also consult their doctor for advice before taking this medicine. To make sure it is safe for you, let your doctor know about all the medicines you are taking.
Some common side effects of this medicine include fever, headache, increased heart rate, anemia, low blood platelets, pleuritis, asthma, pneumonia, acute kidney failure, nausea, vomiting, dizziness, constipation, and allergy. Let your doctor know if any of these side effects do not go away on their own or get worse.
Before receiving this medicine, let your doctor know if you have any bleeding disorders or are on any blood-thinning medications. Pregnant or breastfeeding women should also consult their doctor for advice before taking this medicine. To make sure it is safe for you, let your doctor know about all the medicines you are taking.
Uses of Reliseal Injection
Benefits of Reliseal Injection
Treatment of Bleeding
Reliseal Kit helps in controlling bleeding by speeding up blood clotting. It helps to prevent excessive loss of blood, stops bleeding and enhances the healing process. This helps prevent complications of excessive bleeding such as hemorrhage.
Reliseal Kit helps in controlling bleeding by speeding up blood clotting. It helps to prevent excessive loss of blood, stops bleeding and enhances the healing process. This helps prevent complications of excessive bleeding such as hemorrhage.
Side effects of Reliseal Injection
Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them
Common side effects of Reliseal
- Fever
- Headache
- Increased heart rate
- Anemia (low number of red blood cells)
- Low blood platelets
- Pleuritis (inflammation of the tissues that line the lungs and chest cavity)
- Asthma
- Pneumonia
- Kidney damage
- Nausea
- Vomiting
- Dizziness
- Constipation
- Allergy
How to use Reliseal Injection
Your doctor or nurse will give you this medicine. Kindly do not self administer.
How Reliseal Injection works
Reliseal Kit is a combination of three medicines: Aprotinin, Fibrinogen and Thrombin. They work by preventing the breakdown of clots and control excessive bleeding.
Quick tips
- Reliseal Kit helps in controlling excessive bleeding.
- Your doctor may monitor your vision regularly while you are taking this medicine.
- Inform your doctor if you do not notice any improvement within 3 days of the treatment.
- You will be monitored carefully for any allergic reaction to the medicine.
- Inform your doctor if you have kidney problems.
Safety advice

Alcohol
CONSULT YOUR DOCTOR
It is not known whether it is safe to consume alcohol with Reliseal Kit. Please consult your doctor.

Pregnancy
CONSULT YOUR DOCTOR
Reliseal Kit may be unsafe to use during pregnancy. Although there are limited studies in humans, animal studies have shown harmful effects on the developing baby. Your doctor will weigh the benefits and any potential risks before prescribing it to you. Please consult your doctor.

Breast feeding
CONSULT YOUR DOCTOR
Information regarding the use of Reliseal Kit during breastfeeding is not available. Please consult your doctor.

Driving
NOT RELEVANT
Not relevant, as Reliseal Kit is intended for use in hospitalised patients.

Kidney
SAFE IF PRESCRIBED
Reliseal Kit is probably safe to use in patients with kidney disease. Limited data available suggests that dose adjustment of Reliseal Kit may not be needed in these patients. Please consult your doctor.

Liver
CAUTION
Reliseal Kit should be used with caution in patients with liver disease. Dose adjustment of Reliseal Kit may be needed. Please consult your doctor.

Fact Box
Habit Forming
No
Therapeutic Class
BLOOD RELATED
References
- Reliance Life Sciences. ReliSeal. [Accessed 09 Jul. 2021] (online) Available from:
- Aprotinin. Reading, Berkshire: Nordic Pharma Limited; 1998 [revised 25 Nov. 2013]. [Accessed 10 Apr. 2019] (online) Available from:
- Human fibrinogen. Haywards Heath, West Sussex: CSL Behring UK Limited; 2014 [revised 4 Mar. 2016]. [Accessed 10 Apr. 2019] (online) Available from:
- National Institute for Health and Care Excellence. Thrombin injections for pseudoaneurysms. [Accessed 10 Apr. 2019] (online) Available from:

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Patient concerns
I was late on my dates this month and now having heavy bleeding with thick fluid (clots) passage from past 6-7 days This is for the 1st time happening and I am really worried.Please suggest and advice the medication
Dr. Megha Gupta
Obstetrics and Gynaecology
Heavy bleeding is expected after a delayed period. Try Tranexa tablets to control the bleeding.
Suddenly from last two months m having bleeding only for 1 day during periods .I want to know reason behind it.i am taking Diane 35 now.but still the bleeding lasts for 1 day.The flow of bleeding is very slow.kindly give your suggestions.
Dr. Megha Gupta
Obstetrics and Gynaecology
Hi dear. Usually bleeding decreases while on Diane 35. Also amount if bleeding would depend on how you are taking the pills. However don't worry, decrease in bleeding is expected.
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Tata 1mg's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover everything about particular health conditions, lab tests, medicines, all possible side effects, drug interactions, warnings, alerts, etc. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.
Marketer details
Name: Reliance Formulation Pvt Ltd
Address: Reliance Formulation Private Limited, 201-202, Anand Mangal-3, Rajnagar Club Road Ambabadi, Ahmedabad-380015, Gujarat, India
Address: Reliance Formulation Private Limited, 201-202, Anand Mangal-3, Rajnagar Club Road Ambabadi, Ahmedabad-380015, Gujarat, India
Vendor Details
Country of origin: India
Lab tests offered by us
- CBC (Complete Blood Count)
- FBS (Fasting Blood Sugar)
- Thyroid Profile Total (T3, T4 & TSH)
- HbA1c (Glycosylated Hemoglobin)
- Glucose - Postprandial
- Lipid Profile
- Vitamin D (25-Hydroxy)
- Urine R/M (Urine Routine & Microscopy)
- Coronavirus Covid-19 Test (RT-PCR technique)
- LFT (Liver Function Test)
- Kidney Function Test
- TSH (Thyroid Stimulating Hormone) Ultrasensitive
- ESR (Erythrocyte Sedimentation Rate)
- Uric Acid
- Vitamin B12
- C- Reactive Protein Quantitative
- Urine Culture and Sensitivity
- Serum Electrolyte
- Serum Calcium
- Creatinine
- Diabetes Screening
- KFT with Electrolytes (Kidney Function Test with Electrolytes)
- Cholesterol - Total
- Hemoglobin
- Complete Haemogram
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