Rinotec 2 Injection

Reviewed By Dr. Varun Gupta, MD Pharmacology, MBBS

Last updated on 11 Sep 2024 | 01:05 PM (IST)

Rinotec 2 Injection is used in the treatment of cancer of colon and rectum. It shows its working by stopping or slowing down the growth of cancer cells.

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1/2

2 ml Injection

General Information

Contains

Irinotecan (40mg)

Marketer

United Biotech Pvt Ltd

Storage

Store below 25°C

The content is shown in English

Product introduction

Rinotec 2 Injection is given as an IV infusion into vein by a qualified medical professional. Your doctor will decide what dose is necessary and how often you need to take it. This will depend on what you are being treated for and may change from time to time. You should take it exactly as your doctor has advised. Taking it in the wrong way or taking too much can cause very serious side effects. It may take several weeks or months for you to see or feel the benefits but do not stop taking it unless your doctor tells you to.

The most common side effects of this medicine include fatigue, nausea, vomiting, weakness, and hair loss. This medicine may reduce the number of blood cells (decrease red blood and white blood cells) in your blood, thereby, increasing the susceptibility to infections. Inform your doctor if you notice fever, sore throat, and continuous episodes of diarrhea. Regular blood tests are required to check your blood cells along with heart, liver, and blood uric acid levels.

Before taking it, tell your doctor if you have heart disease, liver, or kidney problems or are taking any medicines to treat infections. Many other medicines can affect, or be affected by, this medicine so let your healthcare team know all medications you are using. This medicine is not recommended during pregnancy or while breastfeeding. The use of effective contraception by both males and females during treatment is important to avoid pregnancy.

Uses of Rinotec Injection

Cancer of colon and rectum

Benefits of Rinotec Injection

Cancer of colon and rectum
Cancer of the colon and rectum, also known as colorectal cancer (CRC) or bowel cancer, is the development of cancer from two parts of the large intestine, namely, the colon or rectum. In this type of cancer, the person may notice symptoms such as blood in the stool, a change in bowel movements, weight loss, and fatigue. Rinotec 2 Injection treats and also lowers the risk of developing further cancerous growths (polyps) and bowel cancer. It kills or stops the growth of cancer cells and also prevents the multiplication of cancer cells. It is an effective, yet very toxic medicine and you should discuss the risks and benefits with your doctor. Avoid drinking alcohol or smoking while having this treatment and drink plenty of water to stay hydrated.

Side effects of Rinotec Injection

Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them

Common side effects of Rinotec

Fatigue
Nausea
Vomiting
Weakness
Hair loss
Fever
Anemia (low number of red blood cells)
Diarrhea
Decreased white blood cell count (neutrophils)
Decreased appetite
Mucosal inflammation

How to use Rinotec Injection

Your doctor or nurse will give you this medicine. Kindly do not self administer.

How Rinotec Injection works

Rinotec 2 Injection is an anti-cancer medication. It works by suppressing the activity of an enzyme (topoisomerase I) involved in DNA multiplication of the cancer cells. This slows the growth of cancer cells and eventually kills them.

All substitutes for Rinotec 2 Injection

For information purposes only. Consult a doctor before taking any medicine.

Quick tips

Rinotec 2 Injection is used in combination with other medicines for the treatment of metastatic cancer of the colon and rectum.
It is given via a drip into a vein (intravenous infusion).
It may cause dizziness and visual disturbances. Do not drive or do anything that requires mental focus until you know how it affects you.
Use a reliable contraceptive method to prevent pregnancy while you are taking this medicine.
Your doctor may get regular blood tests done to monitor your blood cells, kidney and liver function during treatment with this medicine.
Inform your doctor immediately if you notice any signs of infection such as fever, sore throat or rash.
Inform your doctor if you notice passage of blood in stools or experience dizziness or faintness, continuous episodes of nausea, vomiting, diarrhea or fever.

Safety advice

Alcohol

CONSULT YOUR DOCTOR

It is not known whether it is safe to consume alcohol with Rinotec 2 Injection. Please consult your doctor.

Pregnancy

CONSULT YOUR DOCTOR

Rinotec 2 Injection is unsafe to use during pregnancy as there is definite evidence of risk to the developing baby. However, the doctor may rarely prescribe it in some life-threatening situations if the benefits are more than the potential risks. Please consult your doctor.

Breast feeding

UNSAFE

Rinotec 2 Injection is unsafe to use during breastfeeding. Data suggests that the drug may cause toxicity to the baby.

Driving

UNSAFE

Rinotec 2 Injection may decrease alertness, affect your vision or make you feel sleepy and dizzy. Do not drive if these symptoms occur.

Kidney

SAFE IF PRESCRIBED

Rinotec 2 Injection is probably safe to use in patients with kidney disease. Limited data available suggests that dose adjustment of Rinotec 2 Injection may not be needed in these patients. Please consult your doctor.
Use of this medicine is not recommended for patients on dialysis.

Liver

CONSULT YOUR DOCTOR

There is limited information available on the use of Rinotec 2 Injection in patients with liver disease. Please consult your doctor.

Fact Box

Chemical Class

Camptothecin Derivative

Habit Forming

Therapeutic Class

ANTI NEOPLASTICS

Action Class

Topoisomerase Inhibitor

Related lab tests

Carcino Embryonic Antigen

References

Chu E, Sartorelli AC. Cancer Chemotherapy. In: Katzung BG, Masters SB, Trevor AJ, editors. Basic and Clinical Pharmacology. 11th ed. New Delhi, India: Tata McGraw Hill Education Private Limited; 2009. p. 951.
Briggs GG, Freeman RK, editors. A Reference Guide to Fetal and Neonatal Risk: Drugs in Pregnancy and Lactation. 10th ed. Philadelphia, PA: Wolters Kluwer Health; 2015. pp. 736-37.
Irinotecan hydrochloride trihydrate. Sandwich, Kent: Pfizer Limited; 1995 [revised May 2018]. Accessed 26 Jan. 2019] (online) Available from:
Drugs and Lactation Database (LactMed) [Internet]. Bethesda (MD): National Library of Medicine (US); 2006. Irinotecan. [Updated 2018 Dec 3]. [Accessed 18 Feb. 2020] (online) Available from:
Central Drugs Standard Control Organisation (CDSCO). [Accessed 26 Mar. 2019] (online) Available from:

Patient concerns

Is ulcers curable G2 stage of cancer in rectum area

Dr. Pawan Rawal

Gastroenterology

Needs evaluation Please meet a Gastro surgeon

Colon cancer What treat many I have to give

Dr. Aanchal Maheshwari

Ayurveda

Complete reports along with the patient is need to be seen before starting the treatment

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Disclaimer

Tata 1mg's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover everything about particular health conditions, lab tests, medicines, all possible side effects, drug interactions, warnings, alerts, etc. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.

Marketer details

Name: United Biotech Pvt Ltd
Address: FC/B-1 (Extn.), Mohan Co-operative Industrial Estate Mathura Road, New Delhi - 110 044

Vendor Details

Country of origin: India
A licensed vendor partner from your nearest location will deliver Rinotec 2 Injection. Once the pharmacy accepts your order, the details of the pharmacy will be shared with you. Acceptance of your order is based on the validity of your doctor's ℞ and the availability of this medicine.

In case of any issues, contact us

Email ID: [email protected]
Phone Number: 0124-4166666
Address: 5th Floor Tower - B of the Presidency Building, 46/4 Mehrauli Gurgaon Road, Sector 14, Gurugram, Haryana-122001, India

Lab tests offered by us

Why we need a prescription?

Provide right medicines

Prescriptions are complex documents. We proof read and recheck at various steps to provide you the right medication in the correct form and dose

In accordance with the law

Most medicines cannot be sold without a valid prescription, as per the Drugs and Cosmetics Act, 1940 and Rules, 1945

Rinotec 2 Injection

General Information

Contains

Marketer

Storage

Product introduction

Uses of Rinotec Injection

Benefits of Rinotec Injection

Side effects of Rinotec Injection

How to use Rinotec Injection

How Rinotec Injection works

All substitutes for Rinotec 2 Injection

Irinotel 40mg Injection

Ertican 40mg Injection

Caitrino CRC Injection

Relitecan 40mg Injection

Irnotop 40mg Injection

Quick tips

Safety advice

Alcohol

Pregnancy

Breast feeding

Driving

Kidney

Liver

Fact Box

Chemical Class

Habit Forming

Therapeutic Class

Action Class

Related lab tests

Carcino Embryonic Antigen

References

Patient concerns

Is ulcers curable G2 stage of cancer in rectum area

Colon cancer What treat many I have to give

Want to know more

Have issue with the content

Disclaimer

Marketer details

Vendor Details

In case of any issues, contact us

Lab tests offered by us

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