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Ristova 500mg Injection

Rituximab (500mg)
Genuine
Authenticity Assured
Prescription
required
Cold stored
Stored between 2-8°C
Ristova 500mg Injection is used in the treatment of non-Hodgkin lymphoma (NHL), rheumatoid arthritis, blood cancer (chronic lymphocytic leukemia), granulomatosis with polyangiitis and microscopic polyangiitis.

Written By Dr. Anuj Saini, MMST, MBBS,
Reviewed By Dr. Lalit Kanodia, MBA, MD Pharmacology,
Last updated on 12 Nov 2024 | 01:05 AM (IST)
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50 ml Injection
Gurgaon
 
 
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General Information

Contains

Rituximab (500mg)

Marketer

Roche Products India Pvt Ltd

Storage

Store in a refrigerator (2 - 8°C). Do not freeze.
The content is shown in English
Ristova 500mg Injection image
Ristova 500mg Injection image

Product introduction

Ristova 500mg Injection is given as an injection under the supervision of doctor. You must take it in a dose as advised by the doctor. Your doctor will decide what dose is necessary and how often you need to take it. This will depend on what you are being treated for and may change from time to time. You should take it exactly as your doctor has advised. Taking it in the wrong way or taking too much can cause very serious side effects. It may take several weeks or months for you to see or feel the benefits but do not stop taking it unless your doctor tells you to.

The most common side effects of this medicine include headache, weakness, edema, infection, and hair loss. This medicine may reduce the number of blood cells (decrease red blood and white blood cells) in your blood, thereby, increasing the susceptibility to infections. Regular blood tests are required to check your blood cells along with hepatitis B.

Before taking it, tell your doctor if you have heart disease, liver, or planning surgery or vaccination or are taking any medicines to treat infections. Many other medicines can affect, or be affected by, this medicine so let your doctor know all medications you are using. This medicine is not recommended during pregnancy or while breastfeeding. The use of effective contraception by both males and females during treatment is important to avoid pregnancy.

There is a Patient Support Program/Patient Assistance Program available in India for this medicine, being managed by Tata 1mg. Please contact your prescribing doctor to know more about the same. You may also call on (1800-102-1618) for more details.

Uses of Ristova Injection

Benefits of Ristova Injection

Non-Hodgkin lymphoma (NHL)
Non-Hodgkin's lymphoma is a cancer of the white blood cells in our body, also called mantle-cell lymphoma. White blood cells are those cells that help us to fight infections. Ristova 500mg Injection lowers immune response and helps to reduce pain and inflammation. It also kills the cancer cells and helps prevent their further growth. Avoid being in crowds and wash your hands often to prevent any infections. Have plenty of fluids, unless otherwise advised by the doctor not to.
Rheumatoid arthritis
Ristova 500mg Injection helps treat inflammation, pain and swelling in rheumatoid arthritis by decreasing the immune system response of the patient. It is given in the dose and frequency that suits your condition. This will be decided by the doctor. You must follow your doctor’s instructions carefully and let your doctor know if you have fever, chills or any bothersome side effects after taking this medicine.
Blood cancer (Chronic lymphocytic leukemia)
Blood cancer, also called leukemia, is a cancer of the blood-forming tissues, that decreases the body's ability to fight infection. Ristova 500mg Injection kills or stops the growth of cancer cells and also prevents the multiplication of cancer cells. It is an effective medicine but you should discuss the side effects and benefits of this medicine with your doctor. Let your doctor know if any of the side effects bothers you.
Granulomatosis with polyangiitis
Granulomatosis with polyangiitis is a condition that causes inflammation of the blood vessels of the ears, nose, throat, lungs, and kidneys. In this condition, the blood flow to these areas may be reduced and it can lead to their damage. Ristova 500mg Injection helps reduce inflammation, pain and swelling and prevents further damage. This improves your quality of life.
Microscopic polyangiitis
Microscopic polyangiitis is an autoimmune disease which occurs in the small blood vessels and may be caused due to problems with the immune system. Ristova 500mg Injection reduces immune response and improves inflammation. This helps to heal this condition and improves your discomfort.

Side effects of Ristova Injection

Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them
Common side effects of Ristova
  • Headache
  • Weakness
  • Infection
  • Chills
  • Decreased white blood cell count (neutrophils)
  • Fever
  • Infusion site reaction
  • Lymphopenia
  • Abdominal pain
  • Back pain

How to use Ristova Injection

Your doctor or nurse will give you this medicine. Kindly do not self administer.

How Ristova Injection works

Ristova 500mg Injection is a monoclonal antibody. It works by targeting the unwanted activity of immune cells (B cells) in rheumatoid arthritis and certain types of cancers.

All substitutes for Ristova 500mg Injection

For information purposes only. Consult a doctor before taking any medicine.

Reditux 500mg Injection

by Dr Reddy's Laboratories Ltd
₹37675.41/injection
2% cheaper
<h3 class=bodySemiBold>Reditux 500mg Injection</h3>

Maball 500mg Injection

by Hetero Drugs Ltd
₹30285.6/injection
21% cheaper
<h3 class=bodySemiBold>Maball 500mg Injection</h3>

Cytomab 500mg Injection

by Alkem Laboratories Ltd
₹38541.44/injection
same price
<h3 class=bodySemiBold>Cytomab 500mg Injection</h3>

Lupiximab 500mg Injection

by Lupin Ltd
₹23125/injection
40% cheaper
<h3 class=bodySemiBold>Lupiximab 500mg Injection</h3>

Enfiera 500mg Injection

by Zydus Lifesciences Ltd
₹34123.3/injection
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<h3 class=bodySemiBold>Enfiera 500mg Injection</h3>

Quick tips

  • It is given as a drip (intravenous infusion) by your doctor or nurse.
  • You may be given some painkillers, antihistamine and possibly steroids before the drip to help prevent infusion reaction.
  • Your doctor may get blood tests done to check for hepatitis B before treatment and to monitor your blood cells during treatment with this medicine.
  • Inform your doctor immediately if you notice any signs of infection such as fever, sore throat or rash.
  • Inform your doctor if you are pregnant, planning to conceive or breastfeeding.
  • Inform your doctor  if you have any heart rhythm problems, if you are having surgery or if you plan to get any vaccinations.

Safety advice

Alcohol

Alcohol

CAUTION
Caution is advised when consuming alcohol with Ristova 500mg Injection. Please consult your doctor.
Pregnancy

Pregnancy

CONSULT YOUR DOCTOR
Ristova 500mg Injection may be unsafe to use during pregnancy. Although there are limited studies in humans, animal studies have shown harmful effects on the developing baby. Your doctor will weigh the benefits and any potential risks before prescribing it to you. Please consult your doctor.
Breast feeding

Breast feeding

SAFE IF PRESCRIBED
Ristova 500mg Injection is probably safe to use during breastfeeding. Limited human data suggests that the drug does not represent any significant risk to the baby.
Driving

Driving

CONSULT YOUR DOCTOR
It is not known whether Ristova 500mg Injection alters the ability to drive. Do not drive if you experience any symptoms that affect your ability to concentrate and react.
Kidney

Kidney

SAFE IF PRESCRIBED
Ristova 500mg Injection is probably safe to use in patients with kidney disease. Limited data available suggests that dose adjustment of Ristova 500mg Injection may not be needed in these patients. Please consult your doctor.
Liver

Liver

CONSULT YOUR DOCTOR
There is limited information available on the use of Ristova 500mg Injection in patients with liver disease. Please consult your doctor.
Use of Ristova 500mg Injection is not recommended in patients with the active liver disease or those who had viral hepatitis as it can reactivate the infection.

Fact Box

Chemical Class

Monoclonal antibody (mAb)

Habit Forming

No

Therapeutic Class

ANTI NEOPLASTICS

Action Class

CD 20 Inhibitor

Related lab tests

Complete Blood Count

Peripheral Smear Examination

Rheumatoid Factor - Agglutination

Rheumatoid Factor - Turbidometry

Rheumatoid Factor IgG Antibody

References

  1. Chabner BA, Barnes J, Neal J, et al. Targeted Therapies: Tyrosine Kinase Inhibitors, Monoclonal Antibodies, and Cytokines. In: Brunton LL, Chabner BA, Knollmann BC, editors. Goodman & Gilman’s: The Pharmacological Basis of Therapeutics. 12th ed. New York, New York: McGraw-Hill Medical; 2011. pp. 1745-48.
  2. Lake DF, Briggs AD, Akporiaye ET. Immunopharmacology. In: Katzung BG, Masters SB, Trevor AJ, editors. Basic and Clinical Pharmacology. 11th ed. New Delhi, India: Tata McGraw Hill Education Private Limited; 2009. p. 978.
  3. Briggs GG, Freeman RK, editors. A Reference Guide to Fetal and Neonatal Risk: Drugs in Pregnancy and Lactation. 10th ed. Philadelphia, PA: Wolters Kluwer Health; 2015. pp. 1225-27.
  4. Rituximab. Garden City, Hertfordshire: Roche Products Limited; 1998 [revised 18 Dec. 2018]. [Accessed 25 Jan. 2019] (online) Available from:
  5. Drugs and Lactation Database (LactMed) [Internet]. Bethesda (MD): National Library of Medicine (US); 2006. Rituximab. [Updated 2020 Jan 20]. [Accessed 18 Feb. 2020] (online) Available from:

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User feedback

Rheumatoid arthritis
69%
Non-Hodgkin lymphoma (NHL)
19%
Others
12%
Poor
46%
Average
38%
Excellent
17%
Weakness
36%
Headache
27%
Hair loss
18%
Infection
18%
With or without food
100%
Expensive
89%
Average
11%
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Disclaimer

Tata 1mg's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover everything about particular health conditions, lab tests, medicines, all possible side effects, drug interactions, warnings, alerts, etc. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.

Marketer details

Name: Roche Products India Pvt Ltd
Address: 1503, 15th Floor, ‘The Capital’, Plot no. C-70, Behind ICICI Bank, BKC, Bandra (E) , Mumbai 400051

Vendor Details

Country of origin: India
A licensed vendor partner from your nearest location will deliver Ristova 500mg Injection. Once the pharmacy accepts your order, the details of the pharmacy will be shared with you. Acceptance of your order is based on the validity of your doctor's â„ž and the availability of this medicine.

In case of any issues, contact us

Email ID: [email protected]
Phone Number: 0124-4166666
Address: 5th Floor Tower - B of the Presidency Building, 46/4 Mehrauli Gurgaon Road, Sector 14, Gurugram, Haryana-122001, India

Lab tests offered by us

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