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Rolimus 10 Tablet

Written By Dr. Anuj Saini, MMST, MBBS
Reviewed By Dr. Ashish Ranjan, MD (Pharmacology), MBBS
Last updated on 12 Nov 2024 | 01:08 AM (IST)
Rolimus 10 Tablet is used for the prevention of organ rejection in transplant patients. It regulates the body’s immune response, so the body can accept the new organ. It is also used in combination with other medicines to treat cancers of breast, pancreas, lungs, and kidney.
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General Information

Contains

Everolimus (10mg)

Marketer

Cipla Ltd

Storage

Store below 30°C
The content is shown in English
Rolimus 10 Tablet image
Rolimus 10 Tablet image

Product introduction

Rolimus 10 Tablet must be taken in a dose and duration as per the prescription. It can be taken with or without food but make sure to take it at about the same time every day. An overdose of this medicine may have serious side effects on the body.

The common side effects of this medicine are weakness, sinus inflammation, infection, fever, cough, etc. If any of the side effects persist or bother you, consult the doctor immediately. Inform the doctor immediately if you experience any allergic reactions (rash, shortness of breath, coughing, swelling, etc.). Always seek medical advice if you have increased thirst or increased frequency of urination, suffer from shortness of breath, cough or fever, or need to receive any vaccination after taking this medication.

Before taking this medicine, it is important to consult your doctor if you have any ongoing medication for any underlying disease. Pregnant and breastfeeding women must inform the doctor prior to the initiation of this treatment. During the treatment, your doctor may advise you for some laboratory tests to know the effects of the medicine in the body. It may affect male or female fertility, so consult the doctor if you are planning to have a child.

There is a Patient Support Program/Patient Assistance Program available in India for this medicine, being managed by Tata 1mg. Please contact your prescribing doctor to know more about the same. You may also call on (1800-102-1618) for more details.

Uses of Rolimus Tablet

Benefits of Rolimus Tablet

Prevention of organ rejection in transplant patients
Rolimus 10 Tablet is used with other medications to prevent organ transplant rejection. Rejection usually happens due to attack by the immune system of the person receiving the transplanted organ on the transplant itself, in people who are receiving any organ transplants, like kidney, liver, heart etc. This medicine reduces the activity of a person's own immune system and prevents any such rejection.

Side effects of Rolimus Tablet

Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them
Common side effects of Rolimus
  • Decreased appetite
  • Increased glucose level in blood
  • Pneumonitis
  • Hypercholesterolemia (high cholesterol)
  • Increased aspartate aminotransferase
  • Decreased white blood cell count (lymphocytes)
  • Lymphopenia
  • Increased alanine aminotransferase
  • Increased triglyceride level in blood
  • Joint pain
  • Pleural effusion
  • Pulmonary edema
  • Rash
  • Diarrhea
  • Infection
  • Breathlessness
  • Stomatitis (Inflammation of the mouth)
  • Fatigue
  • Anemia (low number of red blood cells)
  • Low blood platelets
  • Decreased potassium level in blood
  • Weight loss
  • Taste change

How to use Rolimus Tablet

Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Rolimus 10 Tablet may be taken with or without food, but it is better to take it at a fixed time.

How Rolimus Tablet works

Rolimus 10 Tablet suppresses the activity of body's immune system and prevents rejection of the transplanted organ.

All substitutes for Rolimus 10 Tablet

For information purposes only. Consult a doctor before taking any medicine.

Evermil 10 Tablet

by Glenmark Pharmaceuticals Ltd
₹722.7/tablet
25% cheaper
<h3 class=bodySemiBold>Evermil 10 Tablet</h3>

Rapact 10mg Tablet

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₹2425/tablet
153% costlier
<h3 class=bodySemiBold>Rapact 10mg Tablet</h3>

Evertor 10mg Tablet

by Biocon
₹1425/tablet
48% costlier
<h3 class=bodySemiBold>Evertor 10mg Tablet</h3>

Everotas 10mg Tablet

by Intas Pharmaceuticals Ltd
₹2910/tablet
203% costlier
<h3 class=bodySemiBold>Everotas 10mg Tablet</h3>

Afinitor 10mg Tablet

by Novartis India Ltd
₹1928.6/tablet
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<h3 class=bodySemiBold>Afinitor 10mg Tablet</h3>

Quick tips

  • Rolimus 10 Tablet is given for the treatment of certain cancers and to prevent organ transplant rejection. 
  • Rolimus 10 Tablet may affect male or female fertility; consult your doctor if you are planning to have a child.
  • Inform your doctor straight away if you think you are getting a sore throat or if you have a high temperature. This is because Rolimus 10 Tablet increases your risk of getting an infection.
  • While you are taking Rolimus 10 Tablet do not take any vaccinations without talking to your doctor first.
  • If you are having an operation or dental treatment, always tell the person carrying out the treatment that you are taking Rolimus 10 Tablet.
  • Do not drink grapefruit juice while you are taking this medicine. This is because a chemical in grapefruit juice can interfere with the action of Rolimus 10 Tablet.

Safety advice

Alcohol

Alcohol

CONSULT YOUR DOCTOR
It is not known whether it is safe to consume alcohol with Rolimus 10 Tablet. Please consult your doctor.
Pregnancy

Pregnancy

CONSULT YOUR DOCTOR
Rolimus 10 Tablet is unsafe to use during pregnancy as there is definite evidence of risk to the developing baby. However, the doctor may rarely prescribe it in some life-threatening situations if the benefits are more than the potential risks. Please consult your doctor.
Breast feeding

Breast feeding

CONSULT YOUR DOCTOR
Rolimus 10 Tablet is probably unsafe to use during breastfeeding. Limited human data suggests that the drug may pass into the breastmilk and harm the baby.
Driving

Driving

UNSAFE
Rolimus 10 Tablet may cause side effects which could affect your ability to drive.
As fatigue is a common side effect with Rolimus 10 Tablet and this may affect your ability to drive
Kidney

Kidney

SAFE IF PRESCRIBED
Rolimus 10 Tablet is safe to use in patients with kidney disease. No dose adjustment of Rolimus 10 Tablet is recommended.
Liver

Liver

CAUTION
Rolimus 10 Tablet should be used with caution in patients with liver disease. Dose adjustment of Rolimus 10 Tablet may be needed. Please consult your doctor.
Use of Rolimus 10 Tablet is not recommended in patients with severe liver disease.
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Frequently asked questions

Regular monitoring is required while you are on Rolimus 10 Tablet. The doctor will advise blood tests to see the counts of red blood cells, white blood cells, and platelets since the counts may decrease during treatment with Rolimus 10 Tablet. Also, blood tests will be required to check your kidney function, liver function, blood glucose levels, and cholesterol levels.
You should avoid grapefruit or grapefruit juice while taking Rolimus 10 Tablet. This is because taking them together may increase the levels of Rolimus 10 Tablet in your blood to harmful levels. Avoid the use of live vaccinations and any possible contact with individuals who have received live vaccinations.
Rolimus 10 Tablet can cause serious side effects which include severe allergic reactions, angioedema, and kidney failure which can be severe and can lead to death. It is possible that you may develop an infection or problems related to lung such as breathing problems.
Rolimus 10 Tablet is an anticancer medicine. It belongs to kinase inhibitor class of medicines. It works by reducing the blood supply to the tumor, which slows down the growth and spread of cancer cells.
Usually, Rolimus 10 Tablet is taken once or twice daily. The medicine should always either be taken with food or always be taken without food. Rolimus 10 Tablet should be swallowed whole with water and should not be crushed or chewed.
There is no definite duration of treatment with Rolimus 10 Tablet. Rolimus 10 Tablet is continued till clinical benefit is seen or unacceptable toxicity or side effects occur.
The effect of Rolimus 10 Tablet in shrinking the size of tumor can only be checked by getting regular brain scans. It should be done as advised by your doctor and your treatment plan.
Yes, Rolimus 10 Tablet is cytotoxic against human cancer cells of breast, stomach, prostate, and kidneys (renal cell carcinoma).
Rolimus 10 Tablet is an anticancer medicine. It belongs to kinase inhibitor class of medicines. It works by reducing the blood supply to the tumor, which slows down the growth and spread of cancer cells.
Usually, Rolimus 10 Tablet is taken once or twice daily. The medicine should always either be taken with food or always be taken without food. Rolimus 10 Tablet should be swallowed whole with water and should not be crushed or chewed.
There is no definite duration of treatment with Rolimus 10 Tablet. Rolimus 10 Tablet is continued till clinical benefit is seen or unacceptable toxicity or side effects occur.
Regular monitoring is required while you are on Rolimus 10 Tablet. The doctor will advise blood tests to see the counts of red blood cells, white blood cells, and platelets since the counts may decrease during treatment with Rolimus 10 Tablet. Also, blood tests will be required to check your kidney function, liver function, blood glucose levels, and cholesterol levels.
The effect of Rolimus 10 Tablet in shrinking the size of tumor can only be checked by getting regular brain scans. It should be done as advised by your doctor and your treatment plan.
You should avoid grapefruit or grapefruit juice while taking Rolimus 10 Tablet. This is because taking them together may increase the levels of Rolimus 10 Tablet in your blood to harmful levels. Avoid the use of live vaccinations and any possible contact with individuals who have received live vaccinations.
Rolimus 10 Tablet can cause serious side effects which include severe allergic reactions, angioedema, and kidney failure which can be severe and can lead to death. It is possible that you may develop an infection or problems related to lung such as breathing problems.
Yes, Rolimus 10 Tablet is cytotoxic against human cancer cells of breast, stomach, prostate, and kidneys (renal cell carcinoma).

Fact Box

Chemical Class

Macrolide Lactams

Habit Forming

No

Therapeutic Class

ANTI NEOPLASTICS

Action Class

Immunosuppressant- mTOR inhibitors

Related lab tests

Breast Cancer (CA 15.3/ ER/ PR)

Carcino Embryonic Antigen

Complete Blood Count

References

  1. Krensky AM, Bennett WM, Vincenti F. Immunosuppressants, Tolerogens, and Immunostimulants. In: Brunton LL, Chabner BA, Knollmann BC, editors. Goodman & Gilman’s: The Pharmacological Basis of Therapeutics. New York, New York: McGraw-Hill Medical; 2011. p. 1013.
  2. Briggs GG, Freeman RK, editors. A Reference Guide to Fetal and Neonatal Risk: Drugs in Pregnancy and Lactation. 10th ed. Philadelphia, PA: Wolters Kluwer Health; 2015. p. 526.
  3. Everolimus. East Hanover, New Jersey: Novartis Pharmaceuticals Corporation; 2009 [revised Apr. 2018]. [Accessed 06 Apr. 2019] (online) Available from:
  4. Everolimus. Camberley, Surrey: Novartis Pharmaceuticals UK Ltd.; 2011 [revised 12 Jul 2018]. [Accessed 22 Jan. 2019] (online) Available from:
  5. CiplaMed. Tacrolimus [Prescribing Information]. [Last Updated: 17 May 2021]. [Accessed 20 Feb. 2024] (online) Available from:
  6. Everolimus [Prescribing Information]. Berkeley Heights: Hikma Pharmaceuticals USA Inc.; 2023. [Accessed 20 Feb. 2024] (online) Available from:
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Patient concerns

I want to know the symptoms of cancer as I am a smoker

Dr. Vijay Sharnangat
Dr. Vijay Sharnangat
Medical Oncology and Hematology
Symptoms for cancer depends upon which organ involved. For smokers , definitely chronic , they have possibility to develop lung cancer, head and neck cancers, oesophagus cancer, pancreatic cancer, stomach cancer and so more on. General symptoms would be like loss of appetite, weight loss, low grade fever in some cases, chronic cough for long time.

If any symtom of brest cancer if have whats the cure

Dr. Sanjay Singh Rai
Dr. Sanjay Singh Rai
Medical Oncology and Hematology
First is confirmation of breast cancerChance of cure depends on stage of cancer
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Disclaimer

Tata 1mg's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover everything about particular health conditions, lab tests, medicines, all possible side effects, drug interactions, warnings, alerts, etc. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.

Marketer details

Name: Cipla Ltd
Address: Cipla House, Peninsula Business Park, Ganpatrao Kadam Marg, Lower Parel, Mumbai-400013

Vendor Details

Country of origin: India
A licensed vendor partner from your nearest location will deliver Rolimus 10 Tablet. Once the pharmacy accepts your order, the details of the pharmacy will be shared with you. Acceptance of your order is based on the validity of your doctor's â„ž and the availability of this medicine.

In case of any issues, contact us

Email ID: [email protected]
Phone Number: 0124-4166666
Address: 5th Floor Tower - B of the Presidency Building, 46/4 Mehrauli Gurgaon Road, Sector 14, Gurugram, Haryana-122001, India

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