Yes, Rostar 20 Tablet can make you feel tired. This is because it reduces the energy supply to the muscles in the body. However, the exact reason behind the phenomenon is unknown and needs more research. Tiredness usually occurs after exertion. Generalized fatigue is more often in people with heart disease or those suffering from liver illness. Rostar 20 Tablet also causes muscle damage which further worsens the tiredness. Therefore, you must consult your doctor if you feel tired while taking Rostar 20 Tablet.