


SAMPURE 400MG TABLET
Ademetionine (400mg)
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SAMPURE 400MG TABLET is a medicine used for the treatment of liver disease associated with reduced bile formation (intrahepatic cholestasis). It protects the liver cells from toxins and helps the liver to perform its normal functions.
Written By Dr. Sakshi Jain, MS, BDS,
Reviewed By Dr. Varun Gupta, MD Pharmacology, MBBS,
Last updated on 12 Nov 2024 | 01:05 AM (IST)
Written By Dr. Sakshi Jain, MS, BDS,
Reviewed By Dr. Varun Gupta, MD Pharmacology, MBBS,
Last updated on 12 Nov 2024 | 01:05 AM (IST)
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General Information
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Product introduction
SAMPURE 400MG TABLET may be taken with or without food. The dose will depend on what you are being treated for and your body weight. This medicine needs to be taken regularly to get the most benefit and you may have to take it for several months or longer, so try to get into a routine. Keep using it as prescribed even if your symptoms disappear.
The most common side effects are nausea, diarrhea, upset stomach, constipation, and dizziness. Not everyone gets side effects. If you are worried about them, or they do not go away, let your doctor know. If you have problems with diarrhea your doctor may reduce the dose or stop the treatment. Drink enough of water or fluids to stay hydrated in case of severe diarrhea and constipation.
Before taking this medicine, you should tell your doctor if you are pregnant, planning pregnancy or breastfeeding. Using this medicine can reduce or increase the effect of some other medicines so tell your doctor, all other medicines you are taking. Avoid drinking alcohol as it might increase side effects.
The most common side effects are nausea, diarrhea, upset stomach, constipation, and dizziness. Not everyone gets side effects. If you are worried about them, or they do not go away, let your doctor know. If you have problems with diarrhea your doctor may reduce the dose or stop the treatment. Drink enough of water or fluids to stay hydrated in case of severe diarrhea and constipation.
Before taking this medicine, you should tell your doctor if you are pregnant, planning pregnancy or breastfeeding. Using this medicine can reduce or increase the effect of some other medicines so tell your doctor, all other medicines you are taking. Avoid drinking alcohol as it might increase side effects.
Uses of Sampure Tablet
- Treatment of Liver disease
Benefits of Sampure Tablet
Treatment of Liver disease
Intrahepatic cholestasis is a type of liver disease that is associated with low bile formation. SAMPURE 400MG TABLET is used to treat this condition and may be used alone or with other medicines. It protects the liver cells from toxins and helps the liver to perform its normal functions. Once you start this treatment, it is likely that you will be taking it for a long time. To make the medicine more effective and for general health benefits, stop smoking, maintain a healthy weight, and do not drink too much alcohol.
Intrahepatic cholestasis is a type of liver disease that is associated with low bile formation. SAMPURE 400MG TABLET is used to treat this condition and may be used alone or with other medicines. It protects the liver cells from toxins and helps the liver to perform its normal functions. Once you start this treatment, it is likely that you will be taking it for a long time. To make the medicine more effective and for general health benefits, stop smoking, maintain a healthy weight, and do not drink too much alcohol.
Side effects of Sampure Tablet
Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them
Common side effects of Sampure
- Nausea
- Diarrhea
- Upset stomach
- Constipation
- Dizziness
How to use Sampure Tablet
Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. SAMPURE 400MG TABLET may be taken with or without food, but it is better to take it at a fixed time.
How Sampure Tablet works
SAMPURE 400MG TABLET protects the liver cells from toxins and helps the liver to perform its normal functions.
All substitutes for SAMPURE 400MG TABLET
For information purposes only. Consult a doctor before taking any medicine.
Cirrosam 400 Tablet
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New Nusam 400 Tablet
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₹77.5/tablet
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Efekart 400mg Tablet
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New Adesam 400 Tablet
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₹92.5/tablet
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S-Methiwave 400 Tablet
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₹58.2/tablet
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Quick tips
- It protects the liver cells from toxins and helps the liver to perform its normal functions.
- Take it as per dose and duration suggested by your doctor.
- Diarrhea may occur as a side effect. Drink plenty of fluids and inform your doctor if diarrhea persists or if you find blood in your stools.
- Consult with your doctor if you are pregnant, planning pregnancy or breastfeeding.
Safety advice

Alcohol
CONSULT YOUR DOCTOR
It is not known whether it is safe to consume alcohol with SAMPURE 400MG TABLET. Please consult your doctor.

Pregnancy
CONSULT YOUR DOCTOR
Information regarding the use of SAMPURE 400MG TABLET during pregnancy is not available. Please consult your doctor.

Breast feeding
CONSULT YOUR DOCTOR
Information regarding the use of SAMPURE 400MG TABLET during breastfeeding is not available. Please consult your doctor.

Driving
CONSULT YOUR DOCTOR
It is not known whether SAMPURE 400MG TABLET alters the ability to drive. Do not drive if you experience any symptoms that affect your ability to concentrate and react.

Kidney
CONSULT YOUR DOCTOR
There is limited information available on the use of SAMPURE 400MG TABLET in patients with kidney disease. Please consult your doctor.

Liver
CONSULT YOUR DOCTOR
There is limited information available on the use of SAMPURE 400MG TABLET in patients with liver disease. Please consult your doctor.
Frequently asked questions
SAMPURE 400MG TABLET is a natural substance found in cells, tissue, and body fluids. It is produced from methionine, an amino acid containing sulfur, and adenosine triphosphate (ATP). The nutritional supplement is harvested from yeast (fungus) cell cultures.
SAMPURE 400MG TABLET has been studied extensively for depression, osteoarthritis, and depression. But, there is no conclusive evidence that it is helpful in these conditions.
Patients with bipolar disorder (an illness characterized by mood swings, from depression to mania) should not be given SAMPURE 400MG TABLET for depression as it can worsen symptoms of mania. Also, consult your doctor if you are pregnant or nursing mother, have Parkinson’s disease or if you are HIV-positive.
The side effects of SAMPURE 400MG TABLET are usually not very serious. These side effects include headache, nausea, and diarrhea. However, these effects are not very common.
Information on long term safety of SAMPURE 400MG TABLET is limited. There is one study in which patients took it for 2 years and no serious side effects were reported.
Fact Box
Chemical Class
5'-deoxy-5'-thionucleosides Derivative
Habit Forming
No
Therapeutic Class
GASTRO INTESTINAL
Action Class
Hepatoprotectives
References
- Medscape. Ademetionine. [Accessed 28 Mar. 2019] (online) Available from:
- Drugs.com. Ademetionine. [Accessed 28 Mar. 2019] (online) Available from:
- Central Drugs Standard Control Organisation (CDSCO). [Accessed 02 Dec. 2019] (online) Available from:
- Ademetionine [Product Label]. Ahmedabad, Gujarat: La Renon Healthcare Private Limited; 2022. [Accessed 09 Jun, 2023] (online) Available from:
- Mount Sinai. S-adenosylmethionine. [Accessed 09 Jun, 2023] (online) Available from:
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Tata 1mg's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover everything about particular health conditions, lab tests, medicines, all possible side effects, drug interactions, warnings, alerts, etc. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.
Marketer details
Name: Elder Pharmaceuticals Ltd
Address: “Elder House” Plot No. C-9, Dalia Industrial Estate, Off Veera Desai Road, Andheri (W), Mumbai – 400053.
Address: “Elder House” Plot No. C-9, Dalia Industrial Estate, Off Veera Desai Road, Andheri (W), Mumbai – 400053.
Vendor Details
Country of origin: India
Lab tests offered by us
- CBC (Complete Blood Count)
- FBS (Fasting Blood Sugar)
- Thyroid Profile Total (T3, T4 & TSH)
- HbA1c (Glycosylated Hemoglobin)
- Glucose - Postprandial
- Lipid Profile
- Vitamin D (25-Hydroxy)
- Urine R/M (Urine Routine & Microscopy)
- Coronavirus Covid-19 Test (RT-PCR technique)
- LFT (Liver Function Test)
- Kidney Function Test
- TSH (Thyroid Stimulating Hormone) Ultrasensitive
- ESR (Erythrocyte Sedimentation Rate)
- Uric Acid
- Vitamin B12
- C- Reactive Protein Quantitative
- Urine Culture and Sensitivity
- Serum Electrolyte
- Serum Calcium
- Creatinine
- Diabetes Screening
- KFT with Electrolytes (Kidney Function Test with Electrolytes)
- Cholesterol - Total
- Hemoglobin
- Complete Haemogram
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