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Sebivo 600mg Tablet

Written By Dr. Love Sharma, PhD (Pharmacology), PGDPRA
Reviewed By Dr. Shilpa Garcha, MD (Pharmacology), MBBS
Last updated on 12 Nov 2024 | 01:06 AM (IST)
Sebivo 600mg Tablet is used in the treatment of HIV infection and chronic hepatitis B virus (HBV) infection. It prevents the multiplication of virus in human cells. This stops the virus from producing new viruses and clears up your infection.
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General Information

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Product introduction

Sebivo 600mg Tablet is prescribed in combination with other HIV medicines. Your doctor will recommend the best medicines for you and will decide the doses that you need. Follow carefully the instructions for all the medicines that you are given. It can be taken with or without food. Taking all these medicines regularly at the right times greatly increases their effectiveness and reduces the chances of HIV becoming resistant to them. It is important not to miss doses and to keep taking them until your doctor tells you it is safe to stop.

Common side effects of this medicine include nausea, stomach pain, weakness and headache. These are usually not serious but tell your doctor if they bother you or do not go away. Rarely, some people may experience a skin reaction or liver damage. Your doctor will closely monitor you for these in the initial period of treatment.

Before taking it, tell your doctor if you have any skin problems or liver or kidney disease. While using it, you may need regular blood tests to check your blood counts and liver function. Avoid drinking alcohol as it may increase your risk of liver damage. Pregnant or breastfeeding mothers should consult their doctor before using this medicine. Do not have unprotected sex or share personal items like razors or toothbrushes, if you are HIV positive. Talk to your doctor about safe ways like condoms to prevent HIV transmission during sex.

Benefits of Sebivo Tablet

Treatment of Chronic hepatitis B virus (HBV) infection
Chronic hepatitis B virus infection is a serious liver infection that has been there for at least 6 months and is still not cured. Sebivo 600mg Tablet helps treat this infection effectively. It lowers the chances of complications, such as new infections, and improves one’s quality of life. If this infection is not treated, it can lead to severe liver damage, which can cause other life-threatening problems, such as liver failure, or may also be fatal.

Side effects of Sebivo Tablet

Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them
Common side effects of Sebivo
  • Fatigue
  • Headache
  • Nausea
  • Fever
  • Dizziness
  • Rash
  • Abdominal pain
  • Diarrhea
  • Elevated levels of serum amylase
  • Increased lipase in the blood
  • Increased alanine aminotransferase
  • Cough

How to use Sebivo Tablet

Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Sebivo 600mg Tablet may be taken with or without food, but it is better to take it at a fixed time.

How Sebivo Tablet works

Sebivo 600mg Tablet is an antiviral medication. It prevents the multiplication of virus in human cells. This stops the virus from producing new viruses and clears up your infection.

Quick tips

  • You have been prescribed Sebivo 600mg Tablet for the treatment of chronic hepatitis B virus (HBV) infection.
  • In combination with other medicines, it is used for the treatment of HIV infections.
  • Take it with food, as this increases the absorption of the medicine into the body.
  • Sebivo 600mg Tablet may cause dizziness or sleepiness. Do not drive or do anything requiring concentration until you know how it affects you.
  • You may still develop infections or other illnesses associated with viral infection while taking this medication.
  • You can also pass on HIV or HBV to others. Don't share needles or personal items that can have blood or body fluids on them.
  • During treatment and for at least six months after stopping this medicine, regular blood tests are needed to monitor your liver function, level of hepatitis B virus and blood cells in your blood.

Safety advice

Alcohol

Alcohol

UNSAFE
It is unsafe to consume alcohol with Sebivo 600mg Tablet.
Pregnancy

Pregnancy

SAFE IF PRESCRIBED
Sebivo 600mg Tablet is generally considered safe to use during pregnancy. Animal studies have shown low or no adverse effects to the developing baby; however, there are limited human studies.
Breast feeding

Breast feeding

CONSULT YOUR DOCTOR
Sebivo 600mg Tablet is probably unsafe to use during breastfeeding. Limited human data suggests that the drug may pass into the breastmilk and harm the baby.
Driving

Driving

UNSAFE
Sebivo 600mg Tablet may decrease alertness, affect your vision or make you feel sleepy and dizzy. Do not drive if these symptoms occur.
Kidney

Kidney

CAUTION
Sebivo 600mg Tablet should be used with caution in patients with kidney disease. Dose adjustment of Sebivo 600mg Tablet may be needed. Please consult your doctor.
Regular monitoring of kidney function tests may be advised before you start taking this medicine and while you are taking this medicine.
Liver

Liver

SAFE IF PRESCRIBED
Sebivo 600mg Tablet is safe to use in patients with liver disease. No dose adjustment of Sebivo 600mg Tablet is recommended.

Frequently asked questions

You should take Sebivo 600mg Tablet exactly as prescribed by your doctor and continue taking it till your doctor tells you to stop. It is usually taken once a day on an empty stomach, at least 2 hours after a meal and at least 2 hours before the next meal. It is advised to take it around the same time every day.
Sebivo 600mg Tablet is effective if used in the dose and duration advised by your doctor. Do not stop taking it even if you see improvement in your condition. If you stop using Sebivo 600mg Tablet too early, the symptoms may return or worsen.
Drug resistance is a state where the medicine which was once effective in treating an infection becomes ineffective. This mainly happens due to the ability acquired by the virus or bacteria to get modified inside the body which affects the overall working of the medicine. Hence, the medicine is no longer able to fight against the virus or bacteria. Generally, drug resistance with Sebivo 600mg Tablet is more likely to happen if you take less dose than what is recommended.
Do not stop taking entecavir without consulting your doctor. Stopping entecavir before treatment may worsen your hepatitis. This can happen during the first several months after you stop taking entecavir. Take the medicine strictly as advised and do not miss any dose.
If you forget a dose of Sebivo 600mg Tablet, take it as soon as you remember. However, if it is almost time for your next dose, skip the missed dose and take the next scheduled dose in the prescribed time. Do not double the dose to make up for the missed one as this may increase the chances of developing side effects.
In HBV patients who are diagnosed with HIV, Sebivo 600mg Tablet is not recommended until and unless these patients start taking medicines for HIV management. Starting Sebivo 600mg Tablet in such patients may cause resistance to the prescribed HIV medicines. Therefore, doctors recommend tests for HIV in patients diagnosed with HBV infection before starting treatment with Sebivo 600mg Tablet.
No, Sebivo 600mg Tablet does not cure hepatitis B but may improve the condition of the liver. It may decrease the amount of hepatitis B virus (HBV) present in the body. This is done by limiting the ability of HBV to multiply and further infect new liver cells.

Fact Box

Chemical Class

Synthetic thymidine nucleoside analog

Habit Forming

No

Therapeutic Class

ANTI INFECTIVES

Action Class

Nucleoside/nucleotide reverse transcriptase inhibitors (NRTIs)

References

  1. Acosta EP, Flexner C. Antiviral Agents (Nonretroviral). In: Brunton LL, Chabner BA, Knollmann BC, editors. Goodman & Gilman’s: The Pharmacological Basis of Therapeutics. New York, New York: McGraw-Hill Medical; 2011. p. 1618.
  2. Safrin S. Antiviral Agents. In: Katzung BG, Masters SB, Trevor AJ, editors. Basic and Clinical Pharmacology. 11th ed. New Delhi, India: Tata McGraw Hill Education Private Limited; 2009. p. 870.
  3. Briggs GG, Freeman RK, editors. A Reference Guide to Fetal and Neonatal Risk: Drugs in Pregnancy and Lactation. 10th ed. Philadelphia, PA: Wolters Kluwer Health; 2015. pp. 1320-21.
  4. Telbivudine. East Hanover, New Jersey: Novartis Pharmaceuticals Corporation; 2006 [revised Jan. 2013]. [Accessed 31 Mar. 2019] (online)
  5. Central Drugs Standard Control Organisation (CDSCO). [Accessed 31 Mar. 2019] (online) Available from:
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User feedback

Chronic hepatitis B virus (HBV) infection
100%
Excellent
67%
Average
33%
No Side Effect
100%

Patient concerns

I have HBV related chronic liver problem .Local urologist suggest me to take rapilif d 8 for urine block problem?Can i take that medicine with entavir for hepatitis b virus and cronic liver disease?

Dr. Praveen Pushkar
Dr. Praveen Pushkar
Urology
Yes u can take it

Suffering from Hepatitis B virus from last one week. Please suggest me.

Dr. Anshum Aneja Arora
Dr. Anshum Aneja Arora
Pulmonology
Pls consult a gastroenterologist
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Disclaimer

Tata 1mg's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover everything about particular health conditions, lab tests, medicines, all possible side effects, drug interactions, warnings, alerts, etc. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.

Marketer details

Name: Novartis India Ltd
Address: Sandoz House, Shiv Sagar Estate, Worli Mumbai -400 018, India

Vendor Details

Country of origin: India
A licensed vendor partner from your nearest location will deliver Sebivo 600mg Tablet. Once the pharmacy accepts your order, the details of the pharmacy will be shared with you. Acceptance of your order is based on the validity of your doctor's ℞ and the availability of this medicine.

In case of any issues, contact us

Email ID: [email protected]
Phone Number: 0124-4166666
Address: 5th Floor Tower - B of the Presidency Building, 46/4 Mehrauli Gurgaon Road, Sector 14, Gurugram, Haryana-122001, India
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