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Simbrinza Ophthalmic Suspension
Brinzolamide (1% w/v)+ Brimonidine (0.2% w/v)
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Simbrinza Ophthalmic Suspension is a prescription medicine having a combination of medicines that is used to treat glaucoma. It works by decreasing the pressure of fluid in the eye (aqueous humor), which helps in lowering the increased eye pressure.
Written By Dr. Betina Chandolia, MDS, BDS,
Reviewed By Dr. Lalit Kanodia, MBA, MD Pharmacology,
Last updated on 12 Nov 2024 | 01:12 AM (IST)
Written By Dr. Betina Chandolia, MDS, BDS,
Reviewed By Dr. Lalit Kanodia, MBA, MD Pharmacology,
Last updated on 12 Nov 2024 | 01:12 AM (IST)
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5 ml Ophthalmic Suspension
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General Information
Contains
Brinzolamide (1% w/v)+ Brimonidine (0.2% w/v)
Marketer
Alcon Laboratories
Storage
Store below 30°C
The content is shown in English





Product introduction
Simbrinza Ophthalmic Suspension is to be used only in the affected eye in the dose and duration as advised by the doctor. Wash your hands before using this medicine. It is advised to check the label for directions before use. Do not skip any doses and finish the full course of treatment even if you feel better.
The most common side effects include burning sensation, irritation, itching, and redness at the application site. If these side effects persist for a longer duration, inform your doctor. In case of accidental contact with your ears, nose, or mouth, immediately rinse it off with water. It is advised not to drive or operate heavy machinery immediately after using this medicine as it may cause temporary blurring of vision.
Uses of Simbrinza Ophthalmic Suspension
Benefits of Simbrinza Ophthalmic Suspension
Treatment of Glaucoma
Glaucoma is an eye disease that damages the optic nerve which is essential for proper vision. This damage is often caused by an abnormally high pressure in the eye. Simbrinza Ophthalmic Suspension is used to reduce swelling and pressure inside the eye. This helps prevent complications of glaucoma such as blindness and improves the vision. This medicine may be used alone or with other eye drops. Glaucoma cannot be prevented. Frequent monitoring, regular checkups can help detect the disease in its early stages.
Glaucoma is an eye disease that damages the optic nerve which is essential for proper vision. This damage is often caused by an abnormally high pressure in the eye. Simbrinza Ophthalmic Suspension is used to reduce swelling and pressure inside the eye. This helps prevent complications of glaucoma such as blindness and improves the vision. This medicine may be used alone or with other eye drops. Glaucoma cannot be prevented. Frequent monitoring, regular checkups can help detect the disease in its early stages.
Side effects of Simbrinza Ophthalmic Suspension
Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them
Common side effects of Simbrinza
- Application site reactions (burning, irritation, itching and redness)
- Blurred vision
How to use Simbrinza Ophthalmic Suspension
This medicine is for external use only. Use it in the dose and duration as advised by your doctor. Check the label for directions before use. Hold the dropper close to the eye without touching it. Gently squeeze the dropper and place the medicine inside the lower eyelid. Wipe off the extra liquid.
How Simbrinza Ophthalmic Suspension works
Simbrinza Ophthalmic Suspension is a combination of two medicines: Brinzolamide and Brimonidine. Brinzolamide is an alpha-2 adrenergic receptor agonist while Brimonidine is a sympathomimetic. They work by decreasing the production of aqueous humour (fluid in the eye), thereby lowering the increased eye pressure.
All substitutes for Simbrinza Ophthalmic Suspension
For information purposes only. Consult a doctor before taking any medicine.
Quick tips
- Simbrinza Ophthalmic Suspension is a combination of two medicines that lowers high pressure in the eye and reduces the risk of vision loss.
- Apply pressure on the corner of the eye (close to the nose) for about 1 minute, immediately after instilling the drop.
- If you wear soft contact lenses, remove them before putting in these eye drops and wait at least 15 minutes before putting your lenses back in.
- Do not touch the tip of the dropper to any surface, or to your eye, to avoid contaminating the eye drops.
- Wait for at least 5-10 minutes before delivering the next medication in the same eye to avoid dilution.
- It may cause short term blurring of vision when first used. Use caution before driving or using machines.
- It may cause temporary burning or itching sensation in the eye. Inform your doctor if this does not go away.
- Make sure to use within 4 weeks of opening the bottle.
Safety advice

Alcohol
No interaction found/established

Pregnancy
CONSULT YOUR DOCTOR
Information regarding the use of Simbrinza Ophthalmic Suspension during pregnancy is not available. Please consult your doctor.

Breast feeding
CONSULT YOUR DOCTOR
Information regarding the use of Simbrinza Ophthalmic Suspension during breastfeeding is not available. Please consult your doctor.

Driving
UNSAFE
Simbrinza Ophthalmic Suspension may cause blurring of your vision for a short time just after its use. Do not drive until your vision is clear.

Kidney
No interaction found/established

Liver
No interaction found/established
Fact Box
Habit Forming
No
Therapeutic Class
OPHTHAL
References
- Medscape. Brinzolamide + Brimonidine. [Accessed 25 Apr. 2019] (online) Available from:
- Brinzolamide + Brimonidine tartrate. Camberley, Surrey: Novartis Pharmaceuticals UK Ltd.; 2014 [revised 20 Feb. 2019]. [Accessed 25 Apr. 2019] (online) Available from:
- Brinzolamide [Prescribing Information]. Parsippany, NJ: Teva Pharmaceuticals USA, Inc.; 2021. [Accessed 28th Sept. 2023] (online) Available from:
- Brimonidine tartrate [Prescribing Information]. Bridgewater, NJ: Bausch & Lomb Americas Inc.; 2022. [Accessed 28th Sept. 2023] (online) Available from:
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User feedback
Twice A Day
75%
Thrice A Day
13%
Once A Day
11%
Four Times A Day
1%
Glaucoma
100%
Average
42%
Poor
33%
Excellent
25%
Burning sensation in eye
33%
No Side Effect
33%
Blurred vision
33%
With or without food
67%
With food
33%
Average
56%
Expensive
44%
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Disclaimer
Tata 1mg's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover everything about particular health conditions, lab tests, medicines, all possible side effects, drug interactions, warnings, alerts, etc. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.
Marketer details
Name: Alcon Laboratories
Address: 54/1, Boodhihal, Nelamangala, Bangalore, -562123, Karnataka, India
Address: 54/1, Boodhihal, Nelamangala, Bangalore, -562123, Karnataka, India
Vendor Details
Country of origin: India
A licensed vendor partner from your nearest location will deliver Simbrinza Ophthalmic Suspension. Once the pharmacy accepts your order, the details of the pharmacy will be shared with you. Acceptance of your order is based on the validity of your doctor's ℞ and the availability of this medicine.
Phone Number: 0124-4166666
Address: 5th Floor Tower - B of the Presidency Building, 46/4 Mehrauli Gurgaon Road, Sector 14, Gurugram, Haryana-122001, India
A licensed vendor partner from your nearest location will deliver Simbrinza Ophthalmic Suspension. Once the pharmacy accepts your order, the details of the pharmacy will be shared with you. Acceptance of your order is based on the validity of your doctor's ℞ and the availability of this medicine.
In case of any issues, contact us
Email ID: [email protected]Phone Number: 0124-4166666
Address: 5th Floor Tower - B of the Presidency Building, 46/4 Mehrauli Gurgaon Road, Sector 14, Gurugram, Haryana-122001, India
Lab tests offered by us
- CBC (Complete Blood Count)
- FBS (Fasting Blood Sugar)
- Thyroid Profile Total (T3, T4 & TSH)
- HbA1c (Glycosylated Hemoglobin)
- Glucose - Postprandial
- Lipid Profile
- Vitamin D (25-Hydroxy)
- Urine R/M (Urine Routine & Microscopy)
- Coronavirus Covid-19 Test (RT-PCR technique)
- LFT (Liver Function Test)
- Kidney Function Test
- TSH (Thyroid Stimulating Hormone) Ultrasensitive
- ESR (Erythrocyte Sedimentation Rate)
- Uric Acid
- Vitamin B12
- C- Reactive Protein Quantitative
- Urine Culture and Sensitivity
- Serum Electrolyte
- Serum Calcium
- Creatinine
- Diabetes Screening
- KFT with Electrolytes (Kidney Function Test with Electrolytes)
- Cholesterol - Total
- Hemoglobin
- Complete Haemogram
Why we need a prescription?
Provide right medicines
Prescriptions are complex documents. We proof read and recheck at various steps to provide you the right medication in the correct form and dose
In accordance with the law
Most medicines cannot be sold without a valid prescription, as per the Drugs and Cosmetics Act, 1940 and Rules, 1945













