Sirotem Injection

Temsirolimus (25mg/ml)

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Sirotem Injection is used as a chemotherapy agent for the treatment of kidney cancer and mantle cell lymphoma (a type of cancer of lymph nodes immune cells). It works by blocking abnormal proteins that causes the multiplication of cancer cells. This helps in slowing the growth of tumors.

Written By Dr. Anuj Saini, MMST, MBBS,
Reviewed By Dr. Ashish Ranjan, MD (Pharmacology), MBBS,
Last updated on 04 Nov 2024 | 01:09 AM (IST)

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1 ml Injection

Gurgaon

Payment

Online only

Return

Not available

Expiry after

Sep, 2026

General Information

Contains

Temsirolimus (25mg/ml)

Marketer

Celon Laboratories Ltd

Storage

Store below 30°C

The content is shown in English

Product introduction

Sirotem Injection is a prescription medicine that must be administered by a healthcare professional. You must receive the exact dose of it as per the prescription. An overdose of this medicine may have serious side effects on the body.

Some common side effects of this medicine include rash, weakness, nausea, edema, loss of appetite, anemia, increased glucose level in the blood, increased blood lipid level, and increased alkaline phosphatase level in blood. If any of the side effects persist or bother you, consult the doctor immediately. Inform the doctor immediately if you experience any allergic reactions such as rash, shortness of breath, coughing, and swelling.

Before taking this medicine, it is important to consult your doctor if you have any ongoing medication for any underlying disease. Pregnant and breastfeeding women must inform the doctor prior to the initiation of this treatment. During the treatment, your doctor may advise you for some laboratory tests to know the effects of the medicine in the body.

Uses of Sirotem Injection

Benefits of Sirotem Injection

Treatment of Kidney cancer
Sirotem Injection is used to treat kidney cancer and its associated symptoms such as blood in the urine, unexplained low back pain or weight loss, fatigue, loss of appetite, etc. It stops cancer growth and prevents multiplication of cancer cells. This restricts the advancement of cancer to other unaffected regions. You need to follow your doctor’s instructions very carefully to recover.

Treatment of Mantle-cell lymphoma
Mantle-cell lymphoma is a cancer of the white blood cells in our body, also called non-Hodgkin's lymphoma. White blood cells are those cells that help us to fight infections. Sirotem Injection helps to restrict cancer growth and also blocks the action of other chemicals that are required for cancer growth and further spread. Avoid being in crowds and wash your hands often to prevent any infections. Have plenty of fluids, unless otherwise advised by the doctor not to.

Side effects of Sirotem Injection

Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them

Common side effects of Sirotem

Rash
Weakness
Nausea
Edema (swelling)
Decreased white blood cell count
Increased glucose level in blood
Anemia (low number of red blood cells)
Loss of appetite
Increased blood lipid level
Increased alkaline phosphatase level in blood

How to use Sirotem Injection

Your doctor or nurse will give you this medicine. Kindly do not self administer.

How Sirotem Injection works

Sirotem Injection is a kinase inhibitor. It shows its action by blocking the action of the abnormal protein that causes the multiplication of cancer cells. This may help slow the growth of tumors.

All substitutes for Sirotem Injection

For information purposes only. Consult a doctor before taking any medicine.

Torisel Kit

by Pfizer Ltd

₹74300/injection

55% costlier

Quick tips

Sirotem Injection is given for the treatment of kidney cancer.
Sirotem Injection interferes with wound healing, so it is advisable to use with caution if you have any scheduled surgery.
Inform your doctor if you have diabetes as the use of Sirotem Injection might increase the level of blood sugar. Report excessive thirst or any increase in the volume or frequency of urination.
Report immediately for the occurrence of infections or any new or worsening abdominal pain or blood in their stools after using Sirotem Injection.
Your doctor will monitor your cholesterol level as Sirotem Injection might increase the level of serum triglycerides and cholesterol.
The use of live vaccines, and close contact with those who have received live vaccines, while on Sirotem Injection should be avoided.

Safety advice

Alcohol

CONSULT YOUR DOCTOR

It is not known whether it is safe to consume alcohol with Sirotem Injection. Please consult your doctor.

Pregnancy

CONSULT YOUR DOCTOR

Sirotem Injection is unsafe to use during pregnancy as there is definite evidence of risk to the developing baby. However, the doctor may rarely prescribe it in some life-threatening situations if the benefits are more than the potential risks. Please consult your doctor.

Breast feeding

CONSULT YOUR DOCTOR

Sirotem Injection is probably unsafe to use during breastfeeding. Limited human data suggests that the drug may pass into the breastmilk and harm the baby.

Driving

SAFE

Sirotem Injection does not usually affect your ability to drive.

Kidney

SAFE IF PRESCRIBED

Sirotem Injection is safe to use in patients with kidney disease. No dose adjustment of Sirotem Injection is recommended.

Liver

CAUTION

Sirotem Injection should be used with caution in patients with liver disease. Dose adjustment of Sirotem Injection may be needed. Please consult your doctor.
Use of Sirotem Injection is not advised in some patients with moderate to severe liver disease.

Fact Box

Chemical Class

Macrolide Lactams

Habit Forming

Therapeutic Class

ANTI NEOPLASTICS

Action Class

Immunosuppressant- mTOR inhibitors

Related lab tests

Complete Blood Count

Cyclin D1

References

Chabner BA, Barnes J, Neal J, et al. Targeted Therapies: Tyrosine Kinase Inhibitors, Monoclonal Antibodies, and Cytokines. In: Brunton LL, Chabner BA, Knollmann BC, editors. Goodman & Gilman’s: The Pharmacological Basis of Therapeutics. New York, New York: McGraw-Hill Medical; 2011. pp. 1743-45.
Briggs GG, Freeman RK, editors. A Reference Guide to Fetal and Neonatal Risk: Drugs in Pregnancy and Lactation. 10th ed. Philadelphia, PA: Wolters Kluwer Health; 2015. p. 1325.
Temsirolimus. Sandwich, Kent: Pfizer Limited; 2007 [revised Jan. 2019]. [Accessed 24 Jan. 2019] (online) Available from:
Temsirolimus. Philadelphia, Pennsylvania: Wyeth Pharmaceuticals Inc.; 2007 [revised Apr. 2007]. [Accessed 06 Apr. 2019] (online) Available from:
Drugs.com. Temsirolimus. [Accessed 06 Apr. 2019] (online) Available from:
Central Drugs Standard Control Organisation (CDSCO). [Accessed 06 Apr. 2019] (online) Available from:

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Disclaimer

Tata 1mg's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover everything about particular health conditions, lab tests, medicines, all possible side effects, drug interactions, warnings, alerts, etc. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.

Marketer details

Name: Celon Laboratories Ltd
Address: Plot No 264, Patrika Nagar Madhapur, Hitech City Hyderabad, Telangana India - 500081

Vendor Details

Country of origin: India
A licensed vendor partner from your nearest location will deliver Sirotem Injection. Once the pharmacy accepts your order, the details of the pharmacy will be shared with you. Acceptance of your order is based on the validity of your doctor's ℞ and the availability of this medicine.

In case of any issues, contact us

Email ID: [email protected]
Phone Number: 0124-4166666
Address: 5th Floor Tower - B of the Presidency Building, 46/4 Mehrauli Gurgaon Road, Sector 14, Gurugram, Haryana-122001, India

Lab tests offered by us

Why we need a prescription?

Sirotem Injection

Payment

Return

Expiry after

General Information

Contains

Marketer

Storage

Product introduction

Uses of Sirotem Injection

Benefits of Sirotem Injection

Side effects of Sirotem Injection

How to use Sirotem Injection

How Sirotem Injection works

All substitutes for Sirotem Injection

Torisel Kit

Quick tips

Safety advice

Alcohol

Pregnancy

Breast feeding

Driving

Kidney

Liver

Fact Box

Chemical Class

Habit Forming

Therapeutic Class

Action Class

Related lab tests

Complete Blood Count

Cyclin D1

References

Want to know more

Have issue with the content

Disclaimer

Marketer details

Vendor Details

In case of any issues, contact us

Lab tests offered by us

Related/Popular tests