Solonase 1.5MIU Injection
Written By Dr. Anuj Saini, MMST, MBBS
Reviewed By Dr. Shilpa Garcha, MD (Pharmacology), MBBS
Last updated on 10 Nov 2024 | 01:05 AM (IST)
Solonase 1.5MIU Injection is a medicine used to break down harmful blood clots that have formed in the blood vessels. It is used to treat patients who have suffered a recent heart attack. It is also used in treating conditions such as pulmonary embolism and stroke.
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General Information
Contains
Streptokinase (1.5Million IU)
Marketer
Lee Chem Biotech Pvt Ltd
Storage
Store in a refrigerator (2 - 8°C). Do not freeze.
The content is shown in English


Product introduction
Solonase 1.5MIU Injection is administered under the supervision of a doctor. Your doctor will decide the dose and duration of the medicine for you. The doctor may closely monitor your condition until you become stable.
Use of this medicine may cause injection site bleeding, nausea, allergic reaction, and a decrease in blood pressure. It may increase your risk of bleeding also. Your doctor will explain the benefits and risks associated with this medicine before it is administered. You should continue all your other medicines that are advised by the doctor for your long-term treatment even after this injection.
This medicine is used with caution for some people. Thus, you must inform the doctor if you are suffering from any bleeding disorder, kidney, or liver disease. Also, let your doctor know if you are pregnant or breastfeeding and about all the other medications that you are taking regularly.
Use of this medicine may cause injection site bleeding, nausea, allergic reaction, and a decrease in blood pressure. It may increase your risk of bleeding also. Your doctor will explain the benefits and risks associated with this medicine before it is administered. You should continue all your other medicines that are advised by the doctor for your long-term treatment even after this injection.
This medicine is used with caution for some people. Thus, you must inform the doctor if you are suffering from any bleeding disorder, kidney, or liver disease. Also, let your doctor know if you are pregnant or breastfeeding and about all the other medications that you are taking regularly.
Uses of Solonase Injection
Side effects of Solonase Injection
Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them
Common side effects of Solonase
- Allergic reaction
- Nausea
- Injection site bleeding
- Decrease in blood pressure
How to use Solonase Injection
Your doctor or nurse will give you this medicine. Kindly do not self administer.
How Solonase Injection works
Solonase 1.5MIU Injection works by dissolving the harmful blood clots in the blood vessels. This restores the blood flow to the affected tissue, thereby preventing tissue death and improving outcomes.
Quick tips
- It increases your risk of bleeding. Be careful while shaving, cutting fingernails or toenails, using sharp objects or engaging in contact sports (e.g. football, wrestling).
- Do not discontinue use without consulting your doctor as this may increase your chances of having another heart attack or stroke.
- Solonase 1.5MIU Injection helps break down blood clots in blood vessels, thereby treating conditions such as heart attack, pulmonary embolism, and stroke.
- It should be given as soon as possible (within 12 hours) after the onset of a heart attack.
- It is usually given by your nurse or doctor as an infusion (drip) into a vein.
- It increases your risk of bleeding. Be careful while shaving, cutting fingernails or toenails, using sharp objects or engaging in contact sports (e.g. football, wrestling).
- Do not discontinue use without consulting your doctor as this may increase your chances of having another heart attack or stroke.
Safety advice

Alcohol
CONSULT YOUR DOCTOR
It is not known whether it is safe to consume alcohol with Solonase 1.5MIU Injection. Please consult your doctor.

Pregnancy
CONSULT YOUR DOCTOR
Solonase 1.5MIU Injection may be unsafe to use during pregnancy. Although there are limited studies in humans, animal studies have shown harmful effects on the developing baby. Your doctor will weigh the benefits and any potential risks before prescribing it to you. Please consult your doctor.

Breast feeding
CONSULT YOUR DOCTOR
Information regarding the use of Solonase 1.5MIU Injection during breastfeeding is not available. Please consult your doctor.

Driving
NOT RELEVANT
Not relevant, as Solonase 1.5MIU Injection is intended for use in hospitalised patients.

Kidney
SAFE IF PRESCRIBED
Solonase 1.5MIU Injection is probably safe to use in patients with kidney disease. Limited data available suggests that dose adjustment of Solonase 1.5MIU Injection may not be needed in these patients. Please consult your doctor.
Use of Solonase 1.5MIU Injection is not recommended in patients with severe kidney disease.
Use of Solonase 1.5MIU Injection is not recommended in patients with severe kidney disease.

Liver
CAUTION
Solonase 1.5MIU Injection should be used with caution in patients with severe liver disease. Dose adjustment of Solonase 1.5MIU Injection may be needed. Please consult your doctor.

Frequently asked questions
Yes, Solonase 1.5MIU Injection increases the risk of bleeding. Always be careful while doing activities that may cause an injury or bleeding. Tell your doctor immediately if you notice any abnormal bruising or bleeding.
Solonase 1.5MIU Injection can interact with several medicines. Do not take any medicine without talking to your doctor.
Fact Box
Chemical Class
Amino acids, Peptides analogues
Habit Forming
No
Therapeutic Class
CARDIAC
Action Class
First-Generation Thrombolytics
Related lab tests
References
- Fox KA, White HD, Gersh BJ, et al. Antithrombotic Agents: Platelete Inhibitors, Acute Anticoagulants, Fibrinolytics, and Chronic Anticoagulants. In: Opie LH, Gersh BJ, editors. Drugs for the Heart. 8th ed. Philadelphia, Pennsylvania: Elsevier Saunders; 2013. pp. 384-85.
- Weitz JI. Blood Coagulation and Anticoagulant, Fibrinolytic, and Antiplatelet Drugs. In: Brunton LL, Chabner BA, Knollmann BC, editors. Goodman & Gilman’s: The Pharmacological Basis of Therapeutics. 12th ed. New York, New York: McGraw-Hill Medical; 2011. p. 866.
- Drugs.com. Streptokinase Pregnancy and Breastfeeding Warnings. [Accessed 20 Mar. 2019] (online) Available from:

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Patient concerns
In road accident head and small intestine got injured . 15 stiches on head and operation of 1 inch diameter of intestine . Now spo2 level is dropping to 70% after 1 hour of removing oxygen mask
Dr. Saurabh Arora
Cardiology
Get checked for pulmonary embolism or pneumothorax
GE my self v.k tiwari mbbs md i feel the patient information above is there any blood test for diagnosed pulmonary edema and pulmonary embolism
Dr. Ila Jain Khandelwal
Pathology
Dear Sir There is no specific blood test for diagnosing pulmonary edema and embolism
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Tata 1mg's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover everything about particular health conditions, lab tests, medicines, all possible side effects, drug interactions, warnings, alerts, etc. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.
Marketer details
Name: Lee Chem Biotech Pvt Ltd
Address: 100 Cinemox Kanakya, Mira road (E), Thane, Mumbai.
Address: 100 Cinemox Kanakya, Mira road (E), Thane, Mumbai.
Vendor Details
Country of origin: India
Lab tests offered by us
- CBC (Complete Blood Count)
- FBS (Fasting Blood Sugar)
- Thyroid Profile Total (T3, T4 & TSH)
- HbA1c (Glycosylated Hemoglobin)
- Glucose - Postprandial
- Lipid Profile
- Vitamin D (25-Hydroxy)
- Urine R/M (Urine Routine & Microscopy)
- Coronavirus Covid-19 Test (RT-PCR technique)
- LFT (Liver Function Test)
- Kidney Function Test
- TSH (Thyroid Stimulating Hormone) Ultrasensitive
- ESR (Erythrocyte Sedimentation Rate)
- Uric Acid
- Vitamin B12
- C- Reactive Protein Quantitative
- Urine Culture and Sensitivity
- Serum Electrolyte
- Serum Calcium
- Creatinine
- Diabetes Screening
- KFT with Electrolytes (Kidney Function Test with Electrolytes)
- Cholesterol - Total
- Hemoglobin
- Complete Haemogram
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