Spegra Tablet

Reviewed By Dr. Varun Gupta, MD Pharmacology, MBBS

Last updated on 12 Nov 2024 | 01:09 AM (IST)

Spegra Tablet is a combination of antiretrovirals medicines. It is prescribed to treat HIV (human immunodeficiency virus) infection. It boosts up the immunity to fight against HIV to manage or treat AIDS (acquired immunodeficiency syndrome).

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Prescription

required

Size:

30 tablets

₹4257 MRP ₹4388.53% off

General Information

Contains

Dolutegravir (50mg)+ Emtricitabine (200mg)+ Tenofovir Alafenamide (25mg)

Marketer

Emcure Pharmaceuticals Ltd

Storage

Store below 30°C

The content is shown in English

Product introduction

Spegra Tablet restricts the growth of HIV in the body and reduces the risk of getting HIV-related complications to improve the lifespan of an individual. The medicine can be taken with or without food. Taking these medicines regularly at the same time increases their effectiveness. A dose of this medicine should not be missed as it can affect your recovery. It is important to complete the full course of the treatment until your doctor advises you to stop it. Sudden discontinuation of the treatment may affect the potency of the medicine.

The most common side effects of this medicine are insomnia, fatigue, headache, nausea, adn diarrhea. These side effects are generally temporary, but if they persist or become serious inform your doctor. This medicine can also make you feel lazy or weak, so it is advised to avoid driving. Drinking plenty of fluid can help you to cope up with the side effects, so stay hydrated.

Before starting with the treatment, you should consult your doctor if you are pregnant or breastfeeding, or have any health condition. Your doctor may suggest regular blood tests to check your blood counts, kidney and liver functions, and other health conditions. If you are HIV positive, you should not breastfeed or share personal belongings like razors or toothbrushes. Consult your doctor to know about safe sex methods in order to prevent transmission of HIV during intercourse.

Uses of Spegra Tablet

HIV infection

Benefits of Spegra Tablet

HIV infection
Spegra Tablet prevents HIV from multiplying in the body. It helps control the infection and make the immune system work better. This lowers the chances of getting complications, such as new infections, and improves the quality of life. This medicine is always taken in combination with other antiretroviral medicines.

It is not a cure of HIV or AIDS and should not be used to prevent HIV after accidental exposure to a risk. It is important to take this medicine as prescribed by the doctor. Taking all doses in the right amount at the right times greatly increases the effectiveness of this combination of medicines and reduces the chances of HIV infection becoming resistant to antiretroviral medicines. Although taking this medicine does not prevent the passing of HIV to other people.

Side effects of Spegra Tablet

Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them

Common side effects of Spegra

Insomnia (difficulty in sleeping)
Headache
Nausea
Fatigue
Diarrhea

How to use Spegra Tablet

Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Spegra Tablet may be taken with or without food, but it is better to take it at a fixed time.

How Spegra Tablet works

Spegra Tablet is a combination of three medicines: Dolutegravir, Emtricitabine and Tenofovir Alafenamide. It is an anti-HIV medication and works by preventing the action of reverse transcriptase enzyme. This enzyme is responsible for production of HIV.

Quick tips

Spegra Tablet is given to slow the progress of HIV infection.
Although treatment with Spegra Tablet can reduce the risk of you passing HIV to others through sexual contact, it does not stop it. It is therefore important to use condoms.
If you develop any infection soon after taking Spegra Tablet, inform your doctor. As a result of taking Spegra Tablet, your immune system may start fighting an infection that was present before you started the treatment, but you might not be aware of.
It may cause weakening of your bones. Exercise regularly and take calcium and vitamin D supplements as suggested by your doctor.
It is common for people with HIV to feel low or even depressed, especially soon after the diagnosis has been made. If you have any feelings of depression it is advisable to speak with your doctor.

Safety advice

Alcohol

CAUTION

Caution is advised when consuming alcohol with Spegra Tablet. Please consult your doctor.

Pregnancy

SAFE IF PRESCRIBED

Spegra Tablet is generally considered safe to use during pregnancy. Animal studies have shown low or no adverse effects to the developing baby; however, there are limited human studies.

Breast feeding

CONSULT YOUR DOCTOR

Information regarding the use of Spegra Tablet during breastfeeding is not available. Please consult your doctor.

Driving

CONSULT YOUR DOCTOR

It is not known whether Spegra Tablet alters the ability to drive. Do not drive if you experience any symptoms that affect your ability to concentrate and react.

Kidney

UNSAFE

Spegra Tablet is probably unsafe to use in patients with kidney disease and should be avoided. Please consult your doctor.

Liver

UNSAFE

Spegra Tablet is probably unsafe to use in patients with liver disease and should be avoided. Please consult your doctor.

Fact Box

Habit Forming

Therapeutic Class

ANTI INFECTIVES

Related lab tests

HIV 1 & 2, Ab Western Blot

HIV 1 And 2 Antibody - Chromatography

HIV 1 And 2 Antibody - ELISA

References

Flexner CW. Antiretroviral Agents and Treatment of HIV Infection. In: Brunton LL, Hilal-Dandan R, Knollmann BC (Editors). Goodman & Gilman’s: The Pharmacological Basis of Therapeutics. 13th ed. New York, NY: McGraw-Hill Education; 2018. pp. 1138-1157.
Safrin S. Antiviral Agents. In: Katzung BG, Masters SB, Trevor AJ (Editors). Basic and Clinical Pharmacology. 11th ed. New Delhi, India: Tata McGraw Hill Education Private Limited; 2009. pp. 861-890.
Dolutegravir, emtricitabine and tenofovir alafenamide [FDA Label]. Hyderabad, India: Mylan Laboratories Limited; 2018. [Accessed 16 Apr. 2021] (online) Available from:
Dolutegravir, emtricitabine and tenofovir alafenamide [Prescribing Information]. Anakapalli, India: Laurus Labs Limited; 2023. [Accessed 22 Aug. 2024] (online) Available from:

Patient concerns

i have unprotected sex with my friend. Can I take any drugs now to prevent any STD/HIV infection

Dr. Shyam Gupta

Obstetrics and Gynaecology

Hello PATIENT to 1mg. There is some medicine for prophylactic but you need to see physician for prescription and better you check HIV status of both partner

hello, one of my frnd suffering with hiv infection from last 2yrs her cd4 is more than 470 and viral load is zero undetectable now she is using art medicines i have doubt that can we have to use art medicine in the whole life or can we stop it once we get viral load zero

Dr. Atula Gupta

Dermatology

You still need to be on ART even if the viral load is undetectable

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Marketer details

Name: Emcure Pharmaceuticals Ltd
Address: 255/2, Hinjawadi, Pune - 411057, India

Vendor Details

Country of origin: India

Lab tests offered by us

Why we need a prescription?

Provide right medicines

Prescriptions are complex documents. We proof read and recheck at various steps to provide you the right medication in the correct form and dose

In accordance with the law

Most medicines cannot be sold without a valid prescription, as per the Drugs and Cosmetics Act, 1940 and Rules, 1945