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SPRM Tablet is a medicine used to treat uterine fibroids (a non-cancerous growth in the uterus) in premenopausal women who cannot undergo surgical treatment or have not responded to surgical intervention.

Written By Dr. Betina Chandolia, MDS, BDS,
Reviewed By Dr. Lalit Kanodia, MBA, MD Pharmacology,
Last updated on 12 Nov 2024 | 01:11 AM (IST)
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General Information

The content is shown in English
SPRM Tablet image
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Product introduction

SPRM Tablet reduces symptoms like vaginal bleeding, prolonged periods and lower back pain. It can be taken with or without food, but take it at the same time to get the most benefit. It should be taken in the dose and duration prescribed by your doctor. It is important to note that this medicine makes birth control less effective, so use proper contraceptive methods to avoid pregnancy.

This medicine's most common side effects include amenorrhea (absence of menstrual period), headache, dizziness, fatigue, and nausea. If these bother you or appear serious, let your doctor know. There may be ways of reducing or preventing them. Usually, your periods stop within 10 days of taking it, but if you still experience heavy bleeding, consult with your doctor. This medicine might stop your period for some time, but periods generally return within 4 weeks after the end of each treatment course.

Before taking this medicine, let your doctor know if you have had liver problems or severe asthma. Your doctor may perform regular blood tests to monitor your liver function while taking SPRM Tablet. Inform your doctor about all other medications you are taking, as many of these may make this medicine less effective or change how it works. Inform your doctor if you are pregnant or breastfeeding.


Uses of SPRM Tablet

Benefits of SPRM Tablet

Uterine fibroids
Uterine fibroids are non-cancerous growths of the uterus that often appear during childbearing years. SPRM Tablet helps control the symptoms associated with uterine fibroids such as excessive menstrual bleeding, lower back pain, and also reduces the size of the existing fibroids. It blocks the action of the enzyme responsible for the growth of the broids. As a result they decrease in size and also stop growing further. Take this medicine as advised by the doctor to get the most benefit.

Side effects of SPRM Tablet

Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them
Common side effects of SPRM
  • Absence of menstrual periods
  • Headache
  • Endometrial hyperplasia
  • Fatigue
  • Dizziness
  • Nausea

How to use SPRM Tablet

Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. SPRM Tablet may be taken with or without food, but it is better to take it at a fixed time.

How SPRM Tablet works

SPRM Tablet is a selective progesterone receptor modulator. It works by modifying the action of progesterone (natural female hormone). It is used either before surgery of fibroids or for intermittent (at regular intervals) treatment of fibroids. It helps reduce their size, stops or controls bleeding and increases your red blood cell count.

Quick tips

  • SPRM Tablet is used for the treatment of uterine fibroids and their associated symptoms, such as painful periods, heavy bleeding and pelvic pain.
  • It considerably reduces or stops your menstrual bleeding within the first 10 days of treatment. Notify your doctor if you continue to have heavy bleeding despite taking SPRM Tablet.
  • Your periods will usually start again within four weeks of stopping SPRM Tablet.
  • Use a reliable barrier contraceptive method (such as condoms or a diaphragm) to prevent pregnancy while you are taking SPRM Tablet as it may make hormonal contraceptives (such as pills) less effective.
  • Your doctor may get routine blood tests done to assess the functioning of your liver. Inform your doctor if you notice yellowing of skin/eye, dark urine, or stomach pain.

Safety advice

Alcohol

Alcohol

CONSULT YOUR DOCTOR
It is not known whether it is safe to consume alcohol with SPRM Tablet. Please consult your doctor.
Pregnancy

Pregnancy

UNSAFE
SPRM Tablet is highly unsafe to use during pregnancy. Seek your doctor's advice as studies on pregnant women and animals have shown significant harmful effects to the developing baby.
Breast feeding

Breast feeding

CONSULT YOUR DOCTOR
SPRM Tablet is probably unsafe to use during breastfeeding. Limited human data suggests that the drug may pass into the breastmilk and harm the baby.
Driving

Driving

UNSAFE
SPRM Tablet may cause side effects which could affect your ability to drive.
Kidney

Kidney

CONSULT YOUR DOCTOR
There is limited information available on the use of SPRM Tablet in patients with kidney disease. Please consult your doctor.
Liver

Liver

CONSULT YOUR DOCTOR
There is limited information available on the use of SPRM Tablet in patients with liver disease. Please consult your doctor.

Frequently asked questions

SPRM Tablet acts by blocking the receptors of progesterone, which decreases the levels of progesterone and therefore it is helpful in decreasing the size of fibroids. Fibroids are non-cancerous development around the uterus. When given at a certain prescribed dose, SPRM Tablet inhibits ovulation leading to stopping of periods. As a result, it may benefit women who have heavy bleeding due to fibroids.
No, taking a single tablet of SPRM Tablet does not stop periods, but it may delay or prepone your periods. In some cases you may have bleeding in between your periods. Consult your doctor if this happens.
No, SPRM Tablet cannot be used as a regular contraceptive. It is meant for occasional use as an emergency contraceptive. It is important to know that the safety and effectiveness of SPRM Tablet have not been established for repeated use in one menstrual cycle. Hence, its repeated use is not recommended.
SPRM Tablet should be taken orally as soon as possible after unprotected sex or contraceptive failure and not later than 120 hours (5 days). It can be taken at anytime of the day and before, during or after food. It can be taken at anytime during your menstrual cycle.
If you vomit immediately after taking SPRM Tablet or within 3 hours of taking it, take another tablet of SPRM Tablet. However, if you have vomited after 3 hours of taking the medicine you need not take another tablet.
SPRM Tablet may make your birth control pills less effective and therefore in addition to birth control pills you should continue using condoms till your next period (menses).
While taking SPRM Tablet you should be aware of some important points such as it does not work if you are already pregnant and it is not effective if you have unprotected sex after taking the tablet. It is also important to know that SPRM Tablet does not protect against sexually transmitted diseases such as HIV, syphilis etc.

Fact Box

Chemical Class

Estradiol Derivative

Habit Forming

No

Therapeutic Class

GYNAECOLOGICAL

Action Class

Selective Progesterone receptor modulators(SPRM)

References

  1. Briggs GG, Freeman RK, editors. A Reference Guide to Fetal and Neonatal Risk: Drugs in Pregnancy and Lactation. 10th ed. Philadelphia, PA: Wolters Kluwer Health; 2015. p. 1413.
  2. Ulipristal acetate. London: Gedeon Richter (UK) Ltd.; 2012 [revised 26 Jul. 2018]. [Accessed 03 Apr. 2019] (online) Available from:
  3. Ulipristal acetate [Prescribing Information]. Morristown, NJ: Watson Pharma, Inc.; 2010. [Accessed 20 Feb. 2024] (online) Available from:
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Disclaimer

Tata 1mg's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover everything about particular health conditions, lab tests, medicines, all possible side effects, drug interactions, warnings, alerts, etc. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.

Marketer details

Name: Agoc Care Pvt Ltd
Address: BLOCK NO.110, JIGNESH APP. , NR , NANDIVALI ROAD, DOMBIVALI, MUMBAI

Vendor Details

Country of origin: India
A licensed vendor partner from your nearest location will deliver SPRM Tablet. Once the pharmacy accepts your order, the details of the pharmacy will be shared with you. Acceptance of your order is based on the validity of your doctor's ℞ and the availability of this medicine.

In case of any issues, contact us

Email ID: [email protected]
Phone Number: 0124-4166666
Address: 5th Floor Tower - B of the Presidency Building, 46/4 Mehrauli Gurgaon Road, Sector 14, Gurugram, Haryana-122001, India
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