Sysonide Cream
Written By Dr. Betina Chandolia, MDS, BDS
Reviewed By Dr. Lalit Kanodia, MBA, MD Pharmacology
Last updated on 12 Nov 2024 | 01:06 AM (IST)
Sysonide Cream is a topical steroid use for the treatment of skin conditions with inflammation and itching. It provides relief from swelling, redness, and itching in the affected area by inhibiting the release of substances that cause inflammation.
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General Information
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Product introduction
Sysonide Cream is only meant for external use and should be used as advised by your doctor. You should normally wash and dry the affected area before applying a thin layer of the medicine. Avoid any contact with your eyes, nose, or mouth. Rinse it off with plenty of water in case of accidental contact. Avoid covering the treated area with airtight dressings such as bandages unless directed by a doctor.
Using the medicine may cause burning sensation, irritation, redness, and swelling at the site of application, and rash. These are temporary and usually resolve with time. However, if they persist or worsen, let your doctor know. The medicine is not recommended for pregnant women. Pregnant and breastfeeding mothers should consult their doctors before using this medicine.
Using the medicine may cause burning sensation, irritation, redness, and swelling at the site of application, and rash. These are temporary and usually resolve with time. However, if they persist or worsen, let your doctor know. The medicine is not recommended for pregnant women. Pregnant and breastfeeding mothers should consult their doctors before using this medicine.
Uses of Sysonide Cream
- Skin conditions with inflammation & itching
Benefits of Sysonide Cream
Skin conditions with inflammation & itching
Sysonide Cream is effective in treating skin conditions with inflammation and itching such as eczema, psoriasis, and dermatitis. It works by reducing the actions of chemicals in the body that cause inflammation of the skin.
When used correctly it is a safe and effective treatment. In treating psoriasis, it reduces the scaly, itchy patches which may develop on the elbows, knees, scalp, and other parts of the body. In treating eczema and dermatitis, it reduces the redness, rash, pain, or itchiness caused by your skin’s reaction to an irritant. It thus improves your self-esteem and confidence as your appearance changes.
You should always use the cream or ointment as prescribed and only apply the amount you have been told to. Keep using it for as long as it is prescribed to get the full benefits.
Sysonide Cream is effective in treating skin conditions with inflammation and itching such as eczema, psoriasis, and dermatitis. It works by reducing the actions of chemicals in the body that cause inflammation of the skin.
When used correctly it is a safe and effective treatment. In treating psoriasis, it reduces the scaly, itchy patches which may develop on the elbows, knees, scalp, and other parts of the body. In treating eczema and dermatitis, it reduces the redness, rash, pain, or itchiness caused by your skin’s reaction to an irritant. It thus improves your self-esteem and confidence as your appearance changes.
You should always use the cream or ointment as prescribed and only apply the amount you have been told to. Keep using it for as long as it is prescribed to get the full benefits.
Side effects of Sysonide Cream
Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them
Common side effects of Sysonide
- Application site reactions (burning, irritation, itching and redness)
- Rash
How to use Sysonide Cream
This medicine is for external use only. Use it in the dose and duration as advised by your doctor. Check the label for directions before use. Clean and dry the affected area and apply the cream. Wash your hands after applying, unless hands are the affected area.
How Sysonide Cream works
Sysonide Cream is a mild to moderate strength steroid. It works by blocking the production of certain chemical messengers (prostaglandins) that make the skin red, swollen, and itchy.
Quick tips
- Sysonide Cream is used to treat the redness, swelling, itching, and discomfort of various skin conditions.
- It should be applied to the affected areas as a thin film two or three times daily, or as advised by your doctor.
- Don't use it more often or for longer than advised by your doctor.
- Don't cover the area being treated with airtight dressings such as bandages unless directed by a doctor, as this may increase the risk of side effects.
- If you think the area of skin you are treating has become infected you should stop using Sysonide Cream and consult your doctor.
- Consult your doctor if your skin condition has not improved after four weeks of treatment. Do not use it for more than 4 consecutive weeks at a time.
Safety advice

Alcohol
No interaction found/established

Pregnancy
CONSULT YOUR DOCTOR
Sysonide Cream may be unsafe to use during pregnancy. Although there are limited studies in humans, animal studies have shown harmful effects on the developing baby. Your doctor will weigh the benefits and any potential risks before prescribing it to you. Please consult your doctor.

Breast feeding
SAFE IF PRESCRIBED
Sysonide Cream is probably safe to use during breastfeeding. Limited human data suggests that the drug does not represent any significant risk to the baby.

Driving
No interaction found/established

Kidney
No interaction found/established

Liver
No interaction found/established

Frequently asked questions
No, Sysonide Cream is not safe for babies. It is a corticosteroid and is not approved to be used in children less than 3 months of age. In babies, the absorption of Sysonide Cream is greater as compared to adults which might lead to systemic absorption (absorbed throughout the body) and effects like Adrenal (glands producing steroids) suppression, symptoms of Cushing’s syndrome, high blood sugar, facial swelling, glycosuria (excretion of glucose in urine), withdrawal (weakness, fatigue, decreased appetite, weight loss, nausea, vomiting, diarrhea, abdominal pain), and growth retardation in children.
Yes, Sysonide Cream can cause skin irritation. Though the chances are rare, the irritation can be due to the hypersensitivity of the person towards the medication or any added excipient of the drug. Allergy to corticosteroids may generally appear as inability of the wounds to heal. If symptoms like these appear, then consult your doctor immediately after discontinuing the medicine. The doctor will start appropriate therapy accordingly.
It is a steroid which is used on the skin to treat mild or moderate atopic dermatitis in patients aged 3 months or more. It suppresses your immunity and associated inflammation, thereby relieving inflammatory conditions. Long-term usage should be avoided and do consult your physician before the start of therapy or in case of any skin reaction. Also, you must consult your physician in case your symptoms do not improve with the medication.
No, it is not an over the counter drug. Therefore, you cannot buy this medicine without a prescription. It is a corticosteroid and it suppresses your immunity and also has numerous metabolic side effects hence is not recommended for a long period. Moreover, you should take this medicine only if prescribed by your doctor.
Yes, Sysonide Cream can be applied on the face but with certain precautions. Do not directly apply it on the face. If it is in foam form, dispense it on your hands first and gently massage over the affected areas of the face. It is for external use only. Avoid contact with your eyes or other mucous membranes. Wash your hands after use. Use this medicine exactly as advised by the doctor. Do consult your physician before the start of therapy.
Fact Box
Chemical Class
Glucocorticoids
Habit Forming
No
Therapeutic Class
DERMA
Action Class
Glucocorticoids
References
- Desonide. Buffalo, New York: CPL; 2006. [Accessed 17 Jul. 2019] (online) Available from:
- Desonide. Haifa Bay, Israel: Taro Pharmaceutical Industries Ltd.; 2015. [Accessed 04 Apr. 2019] (online) Available from:
- Mayo Clinic. Desonide. [Accessed 04 Apr. 2019] (online) Available from:
- Central Drugs Standard Control Organisation (CDSCO). [Accessed 04 Apr. 2019] (online) Available from:


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Patient concerns
Allergic skin conditions in leg
Dr. Atula Gupta
Dermatology
kindly send the Pictures of affected area.
I have skin itching during last 20 years. .now using Momate lotion externally. .doxycyclin internally. .it will increase while on hot conditions. .
Dr. Atula Gupta
Dermatology
Need pictures for diagnosis and treatment
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