Temokem 250mg Injection

Reviewed By Dr. Lalit Kanodia, MBA, MD Pharmacology

Last updated on 30 Sep 2024 | 05:25 PM (IST)

Temokem 250mg Injection is used in the treatment of a specific type of brain cancer. It is used to treat brain tumors if they return or get worse after standard treatment. It may be also used to treat other conditions, as determined by the doctor.

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₹18794 MRP ₹193753% off

General Information

Contains

Temozolomide (250mg)

Marketer

Alkem Laboratories Ltd

Storage

Store below 30°C

The content is shown in English

Product introduction

Temokem 250mg Injection is given by a nurse or a doctor. You should not self-administer this medicine. Your doctor will decide what dose is necessary and how often you need to take it. This will depend on the severity of your condition and may change from time to time. It may take several weeks or months for you to see or feel the benefits but do not stop taking it unless your doctor tells you to.

The most common side effects of this medicine include nausea, vomiting, constipation, headache, and fatigue. This medicine may reduce the number of blood cells in your blood thereby, increasing the susceptibility to infections. Regular blood tests are required to check your blood cells along with kidney, liver, and heart function during treatment with this medicine.

Before taking it, tell your doctor if you have bleeding, liver, or kidney problems or are taking any medicines to treat infections. Many other medicines can affect, or be affected by, this medicine so let your doctor know all medications you are using. This medicine is not recommended during pregnancy or while breastfeeding. The use of effective contraception by both males and females during treatment is important to avoid pregnancy.

Uses of Temokem Injection

Brain tumor

Benefits of Temokem Injection

Brain tumor
Brain tumor is an abnormal mass or collection of cells that may be cancerous (malignant) or non-cancerous (benign). Temokem 250mg Injection kills or stops the growth of cancer cells and also prevents the multiplication of cancer cells. It is a potent and very toxic medicine and you should discuss the risks and benefits with your doctor. You should avoid drinking alcohol while having this treatment and drink plenty of water to stay hydrated.

Side effects of Temokem Injection

Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them

Common side effects of Temokem

Memory loss
Rash
Headache
Dizziness
Convulsion
Coordination disorder
Insomnia (difficulty in sleeping)
Vomiting
Weakness
Nausea
Loss of appetite
Hair loss
Fatigue
Fever
Diarrhea
Constipation
Hemiparesis (weakness on one side of the body)
Viral infection

How to use Temokem Injection

Your doctor or nurse will give you this medicine. Kindly do not self administer.

How Temokem Injection works

Temokem 250mg Injection is an anti-cancer medication. It enters the brain tissues and works by damaging the genetic material (DNA and RNA) of the cancer cells. This stops their growth and multiplication.

Quick tips

Temokem 250mg Injection is given as an injection into the vein under the supervision of a doctor only.
Do not skip any dose and complete the course as suggested by your doctor.
Use an effective method of birth control to avoid pregnancy while taking this medication.
It increases your risk of bleeding. Be careful while shaving, cutting fingernails or toenails, or using sharp objects.
Your doctor may get regular blood tests done to monitor your blood cell count and liver function.
Inform your doctor if you experience severe skin rash, fever, chills, headache and shortness of breath during the treatment.

Safety advice

Alcohol

CONSULT YOUR DOCTOR

It is not known whether it is safe to consume alcohol with Temokem 250mg Injection. Please consult your doctor.

Pregnancy

CONSULT YOUR DOCTOR

Temokem 250mg Injection is unsafe to use during pregnancy as there is definite evidence of risk to the developing baby. However, the doctor may rarely prescribe it in some life-threatening situations if the benefits are more than the potential risks. Please consult your doctor.

Breast feeding

UNSAFE

Temokem 250mg Injection is unsafe to use during breastfeeding. Data suggests that the drug may cause toxicity to the baby.

Driving

UNSAFE

Temokem 250mg Injection may decrease alertness, affect your vision or make you feel sleepy and dizzy. Do not drive if these symptoms occur.

Kidney

SAFE IF PRESCRIBED

Temokem 250mg Injection is probably safe to use in patients with kidney disease. Limited data available suggests that dose adjustment of Temokem 250mg Injection may not be needed in these patients. Please consult your doctor.
Cautious use is advised in patients with severe kidney disease while they are taking Temokem 250mg Injection.

Liver

CAUTION

Temokem 250mg Injection should be used with caution in patients with severe liver disease. Dose adjustment of Temokem 250mg Injection may be needed. Please consult your doctor.
Limited information is available on the use of Temokem 250mg Injection in these patients. No dose adjustment is recommended in patients with mild to moderate liver disease.

Fact Box

Chemical Class

Dacarbazine Derivative

Habit Forming

Therapeutic Class

ANTI NEOPLASTICS

Action Class

Alkylating agent

References

Chabner BA, Bertino J, Cleary J, et al. Cytotoxic Agents. In: Brunton LL, Chabner BA, Knollmann BC, editors. Goodman & Gilman’s: The Pharmacological Basis of Therapeutics. 12th ed. New York, New York: McGraw-Hill Medical; 2011. p. 1687.
Briggs GG, Freeman RK, editors. A Reference Guide to Fetal and Neonatal Risk: Drugs in Pregnancy and Lactation. 10th ed. Philadelphia, PA: Wolters Kluwer Health; 2015. pp. 1324-25.
Temozolomide. Whitehouse Station, New Jersey: Merck & Co., Inc.; 1999 [revised Sep. 2015]. [Accecssed 25 Jan. 2019] (online) Available from:
Drugs and Lactation Database (LactMed) [Internet]. Bethesda (MD): National Library of Medicine (US); 2006. Temozolamide. [Updated 2018 Dec 3]. [Accessed 18 Feb. 2020] (online) Available from:
Central Drugs Standard Control Organisation (CDSCO). [Accessed 27 Mar. 2019] (online) Available from:

Patient concerns

any treatment of brain tumor w

Dr. Saurav Arora

Homeopathy

Dear sir in this case homeopathy can be given as add-on with conventional medicine. By doing so we can improve the longevity of patient, quality of life and decrease disease progression.

He is suffering of brain tumor gbm4 glioblastoma

Dr. Deepak Kumar Soni

Ayurveda

Hi Kindly consult to Ayurvedic doctor at your local city area , face to face consult is needed.

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Tata 1mg's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover everything about particular health conditions, lab tests, medicines, all possible side effects, drug interactions, warnings, alerts, etc. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.

Marketer details

Name: Alkem Laboratories Ltd
Address: Alkem Laboratories Limited, Devashish Building, Alkem House, Senapati Bapat Road, Lower Parel, Mumbai - 400 013.

Vendor Details

Country of origin: India

Lab tests offered by us

Why we need a prescription?

Provide right medicines

Prescriptions are complex documents. We proof read and recheck at various steps to provide you the right medication in the correct form and dose

In accordance with the law

Most medicines cannot be sold without a valid prescription, as per the Drugs and Cosmetics Act, 1940 and Rules, 1945