Therotepa 100 Injection

Reviewed By Dr. Ashish Ranjan, MD (Pharmacology), MBBS

Last updated on 31 Oct 2024 | 01:10 AM (IST)

Therotepa 100 Injection is used in the treatment of cancers of the brain, breast, lungs, and ovaries. It is used in combination with other cancer medicine during hematopoietic progenitor cell transplantation (HPCT). It may be also used to treat other conditions, as determined by the doctor.

Genuine

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Cold stored

Stored between 2-8°C

₹63000

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₹62500

on orders above ₹150

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₹62600

on orders above ₹200

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1/2

1 Injection

General Information

Contains

Thiotepa (100mg)

Marketer

Therdose Pharma Pvt Ltd

Storage

Store in a refrigerator (2 - 8°C). Do not freeze.

The content is shown in English

Product introduction

Therotepa 100 Injection is generally given under the supervision of a healthcare professional. Your doctor will decide the dose and duration of the treatment based on the severity of your condition and what you are being treated for. It may take several weeks or months for you to see or feel the benefits but do not stop getting the injection unless your doctor tells you to.

The most common side effects of this medicine include decreased white blood count, anemia, low blood platelets, increased liver enzymes, increased bilirubin in the blood, mucosal inflammation, hemorrhage, diarrhea, blood in urine, and rash. This medicine may reduce the number of blood cells in your blood, thereby, increasing the susceptibility to infections. Regular blood tests are required to check your blood cells along with kidneys, liver, and heart function during treatment with this medicine.

Before taking it, tell your doctor if you have bleeding, liver, or kidney problems or are taking any medicines to treat infections. Many other medicines can affect, or be affected by, this medicine so let your doctor know all medications you are using. This medicine is not recommended during pregnancy or while breastfeeding. The use of effective contraception by both males and females during treatment is important to avoid pregnancy.

Uses of Therotepa Injection

Benefits of Therotepa Injection

Non-small cell lung cancer
Non-small cell lung cancer is one of the major kinds of lung cancer and it affects both smokers as well as non-smokers. Therotepa 100 Injection helps treat non-small cell lung cancer and may be given alone or in combination with other medicines. It is a potent and very toxic medicine and you should discuss the risks and benefits with your doctor. You should avoid drinking alcohol while having this treatment and drink plenty of water to stay hydrated.

Ovarian cancer
Ovarian cancer is a cancer that begins in the female organs that produce eggs (ovaries). This type of cancer is usually detected very late and can be fatal too. It usually spreads to the pelvis and stomach. Therotepa 100 Injection kills or stops the growth of cancer cells and also prevents the multiplication of cancer cells. It is an effective medicine but has some side effects that may be bothersome. So, you should discuss the risks and benefits with your doctor.

Side effects of Therotepa Injection

Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them

Common side effects of Therotepa

Decreased white blood cell count (neutrophils)
Anemia (low number of red blood cells)
Low blood platelets
Increased liver enzymes
Increased bilirubin in the blood
Mucosal inflammation
Hemorrhage
Rash
Diarrhea
Blood in urine

How to use Therotepa Injection

Your doctor or nurse will give you this medicine. Kindly do not self administer.

How Therotepa Injection works

Therotepa 100 Injection is an anti-cancer medication. It works by damaging the genetic material (DNA and RNA) of the cancer cells. This stops their growth and multiplication.

All substitutes for Therotepa 100 Injection

For information purposes only. Consult a doctor before taking any medicine.

Quick tips

Therotepa 100 Injection is given as an intravenous infusion (IV infusion) under the supervisión of a doctor.
Do not skip any dose and complete the course as suggested by your doctor.
Use an effective method of birth control to avoid pregnancy while taking this medication.
Your doctor may get regular blood tests done to monitor your blood cell count, platelet count and liver function.
It makes you feel dizzy. Do not drive or operate machinery until you know how it affects you.

Safety advice

Alcohol

CONSULT YOUR DOCTOR

It is not known whether it is safe to consume alcohol with Therotepa 100 Injection. Please consult your doctor.

Pregnancy

CONSULT YOUR DOCTOR

Therotepa 100 Injection is unsafe to use during pregnancy as there is definite evidence of risk to the developing baby. However, the doctor may rarely prescribe it in some life-threatening situations if the benefits are more than the potential risks. Please consult your doctor.

Breast feeding

UNSAFE

Therotepa 100 Injection is unsafe to use during breastfeeding. Data suggests that the drug may cause toxicity to the baby.

Driving

UNSAFE

Therotepa 100 Injection may cause side effects which could affect your ability to drive.
It is likely that certain adverse events of Therotepa 100 Injection are dizziness, headache, and blurred vision which could affect your ability to drive.

Kidney

SAFE IF PRESCRIBED

Therotepa 100 Injection is probably safe to use in patients with kidney disease. Limited data available suggests that dose adjustment of Therotepa 100 Injection may not be needed in these patients. Please consult your doctor.

Liver

CAUTION

Therotepa 100 Injection should be used with caution in patients with liver disease. Dose adjustment of Therotepa 100 Injection may be needed. Please consult your doctor.
Regular monitoring of liver function tests may be advised while you are taking this medicine.

Fact Box

Chemical Class

Thiophosphoric Acids Derivatives

Habit Forming

Therapeutic Class

ANTI NEOPLASTICS

Action Class

Alkylating agent

Related lab tests

Breast Cancer (CA 15.3/ ER/ PR)

References

Chabner BA, Bertino J, Cleary J, et al. Cytotoxic Agents. In: Brunton LL, Chabner BA, Knollmann BC, editors. Goodman & Gilman’s: The Pharmacological Basis of Therapeutics. 12th ed. New York, New York: McGraw-Hill Medical; 2011. p. 1685.
Briggs GG, Freeman RK, editors. A Reference Guide to Fetal and Neonatal Risk: Drugs in Pregnancy and Lactation. 10th ed. Philadelphia, PA: Wolters Kluwer Health; 2015. pp. 1355-56.
Thiotepa. Lugano, Switzerland: ADIENNE SA; 1959 [revised Jan. 2017]. [Accessed 27 Mar. 2019] (online) Available from:
Drugs.com. Thiotepa Pregnancy and Breastfeeding Warnings. [Accessed 27 Mar. 2019] (online) Available from:

Patient concerns

What is the purpose of Chemotherepy given at the time of radiotherapy in ca lung small cell carcinoma

Dr. Vijay Sharnangat

Medical Oncology and Hematology

This is given to enhance the therapeutic effect of radiation therapy which is curative for small cell lung cancer.

My mother have ovarian cancer. I want to consult docter how much serious my mother according to reports When will i get my answer

Dr. Sanjay Singh Rai

Medical Oncology and Hematology

U have to do FNAC from tumorIf positive for cancer Chemotherapy will be done

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Tata 1mg's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover everything about particular health conditions, lab tests, medicines, all possible side effects, drug interactions, warnings, alerts, etc. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.

Marketer details

Name: Therdose Pharma Pvt Ltd
Address: Plot No's : 118 - 120, Road No.6, ALEAP IE, Pragathi Nagar, Gajularamaram Village, Kukatpally, Hyderabad ,Telangana - 500 072, India.

Vendor Details

Country of origin: India
A licensed vendor partner from your nearest location will deliver Therotepa 100 Injection. Once the pharmacy accepts your order, the details of the pharmacy will be shared with you. Acceptance of your order is based on the validity of your doctor's ℞ and the availability of this medicine.

In case of any issues, contact us

Email ID: [email protected]
Phone Number: 0124-4166666
Address: 5th Floor Tower - B of the Presidency Building, 46/4 Mehrauli Gurgaon Road, Sector 14, Gurugram, Haryana-122001, India

Lab tests offered by us

Why we need a prescription?

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In accordance with the law

Most medicines cannot be sold without a valid prescription, as per the Drugs and Cosmetics Act, 1940 and Rules, 1945