Tirofuse Injection
Written By Dr. Anuj Saini, MMST, MBBS
Reviewed By Dr. Varun Gupta, MD Pharmacology, MBBS
Last updated on 12 Nov 2024 | 01:01 AM (IST)
Tirofuse Injection is a blood thinner which prevents formation of harmful blood clots. It helps to prevent a heart attack in patients presenting with severe chest pain due to a sudden decrease in blood flow to the heart.
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General Information
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Product introduction
Tirofuse Injection is administered under the supervision of a doctor. Your doctor will decide the dose and duration of the medicine for you. You should continue all your other medicines that are advised by the doctor for your long term treatment even after this injection.
Common side effects of this medicine include headaches, hematoma, nausea, ecchymosis, postoperative bleeding, and blood in stool or urine. Let your doctor know immediately if you see pinpoint rash or blood in your vomits, urine, or stool.
This medicine is used with caution for some people. Before taking it, you must inform the doctor if you are suffering from any bleeding disorder, kidney, or liver disease. Also, let your doctor know if you are breastfeeding and about all the other medications that you are taking regularly.
Common side effects of this medicine include headaches, hematoma, nausea, ecchymosis, postoperative bleeding, and blood in stool or urine. Let your doctor know immediately if you see pinpoint rash or blood in your vomits, urine, or stool.
This medicine is used with caution for some people. Before taking it, you must inform the doctor if you are suffering from any bleeding disorder, kidney, or liver disease. Also, let your doctor know if you are breastfeeding and about all the other medications that you are taking regularly.
Uses of Tirofuse Infusion
- Prevention of Heart attack
- Unstable angina
Benefits of Tirofuse Infusion
Prevention of Heart attack
It prevents blood from clotting inside the veins and arteries. This helps the blood flow freely around your body thereby preventing a heart attack or stroke (or deep vein thrombosis or pulmonary embolism). Follow your doctor’s instructions carefully and make appropriate lifestyle changes (such as eating healthy and staying active) to maximize the effectiveness of this medicine.
It prevents blood from clotting inside the veins and arteries. This helps the blood flow freely around your body thereby preventing a heart attack or stroke (or deep vein thrombosis or pulmonary embolism). Follow your doctor’s instructions carefully and make appropriate lifestyle changes (such as eating healthy and staying active) to maximize the effectiveness of this medicine.
Side effects of Tirofuse Infusion
Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them
Common side effects of Tirofuse
- Headache
- Nausea
- Hematoma
- Ecchymosis (discoloration of the skin resulting from bleeding underneath)
- Postoperative bleeding
- Blood in stool
- Blood in urine
How to use Tirofuse Infusion
Your doctor or nurse will give you this medicine. Kindly do not self-administer.
How Tirofuse Infusion works
Tirofuse Injection is an antiplatelet medication. It works by preventing the platelets from sticking together, thereby decreasing the formation of harmful blood clots. This lowers the chance of heart attack or stroke.
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For information purposes only. Consult a doctor before taking any medicine.
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Quick tips
- It increases your risk of bleeding. Be careful while shaving, cutting fingernails or toenails or using sharp objects.
- Notify your doctor if you see blood in your vomit, urine or stool (black, tarry stools or bright red blood).
Safety advice

Alcohol
CONSULT YOUR DOCTOR
It is not known whether it is safe to consume alcohol with Tirofuse Injection. Please consult your doctor.

Pregnancy
SAFE IF PRESCRIBED
Tirofuse Injection is generally considered safe to use during pregnancy. Animal studies have shown low or no adverse effects to the developing baby; however, there are limited human studies.

Breast feeding
CAUTION
Tirofuse Injection should be used with caution during breastfeeding. Breastfeeding should be held until the treatment of the mother is completed and the drug is eliminated from her body.

Driving
NOT RELEVANT
Not relevant, as Tirofuse Injection is intended for use in hospitalised patients.

Kidney
CAUTION
Tirofuse Injection should be used with caution in patients with kidney disease. Dose adjustment of Tirofuse Injection may be needed. Please consult your doctor.

Liver
CAUTION
Tirofuse Injection should be used with caution in patients with liver disease. Dose adjustment of Tirofuse Injection may be needed. Please consult your doctor.
Use of Tirofuse Injection is not recommended in patients with severe liver disease.
Use of Tirofuse Injection is not recommended in patients with severe liver disease.
Frequently asked questions
Yes, Tirofuse Injection increases the risk of bleeding. Always be careful while doing activities that may cause an injury or bleeding. Tell your doctor immediately if you notice any abnormal bruising or bleeding.
Tirofuse Injection can interact with several medicines. Do not take any medicine without talking to your doctor.
Tirofuse Injection reduces your risk of developing blood clots in the blood vessels of your leg, lungs, heart and brain. You may not feel any difference after taking Tirofuse Injection. However, keep taking this medicine as prescribed by your doctor because you will still be getting its full benefits.
Fact Box
Chemical Class
Phenylalanine derivatives
Habit Forming
No
Therapeutic Class
BLOOD RELATED
Action Class
Glycoprotein IIb/IIIa Inhibitors
References
- Weitz JI. Blood Coagulation and Anticoagulant, Fibrinolytic, and Antiplatelet Drugs. In: Brunton LL, Chabner BA, Knollmann BC, editors. Goodman & Gilman’s: The Pharmacological Basis of Therapeutics. 12th ed. New York, New York: McGraw-Hill Medical; 2011. pp. 871-72.
- Fox KA, White HD, Gersh BJ, et al. Antithrombotic Agents: Platelete Inhibitors, Acute Anticoagulants, Fibrinolytics, and Chronic Anticoagulants. In: Opie LH, Gersh BJ, editors. Drugs for the Heart. 8th ed. Philadelphia, Pennsylvania: Elsevier Saunders; 2013. p. 355.
- Briggs GG, Freeman RK, editors. A Reference Guide to Fetal and Neonatal Risk: Drugs in Pregnancy and Lactation. 10th ed. Philadelphia, PA: Wolters Kluwer Health; 2015. pp. 1369-70.
- Central Drugs Standard Control Organisation (CDSCO). [Accessed 19 Mar. 2019] (online) Available from:
- Tirofiban hydrochloride monohydrate. Uxbridge, UK: Correvio UK Ltd.; 1999 [03 Dec. 2014]. [Accessed 24 Jan. 2019] (online) Available from:
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Unstable angina
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Patient concerns
What is heart attack? When heart attack coming?
Dr. Nabajit Talukdar
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Related to chest pain angina commonly
mild heart attack few weeks ago. Coronary Artery Disease - Unstable Angina, Anterior Lateral Wall Ischemia, Mild LV Dysfunctional(EF-52%), Mild to Moderate AR, Mild PAH, TROP - I Positive
Dr. Deepak Kumar Soni
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Hi Kindly consult to Ayurvedic doctor at your local city area , face to face consult is needed.
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