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Trihexol Forte Tablet

Written By Dr. Swati Mishra, BDS
Reviewed By Dr. Shilpa Garcha, MD (Pharmacology), MBBS
Last updated on 26 Jul 2024 | 05:45 PM (IST)
Trihexol Forte Tablet is used with other medicines to treat Parkinson’s disease. It’s also used to treat severe movement side effects caused by certain drugs (drug-induced movement disorder).
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General Information

Contains

Trihexyphenidyl (NA)

Marketer

Chicky Pharma Pvt Ltd

Storage

Store below 30°C
The content is shown in English
Trihexol Forte Tablet image

Product introduction

Trihexol Forte Tablet should be taken empty stomach as it reduces the side effects of this medicine. It should be taken at the same time each day, this helps to maintain a consistent level of medicine in the body. Take this medicine in the dose and duration as advised by your doctor and if you have missed a dose, take it as soon as you remember. Do not skip any doses and finish the full course of treatment even if you feel better. This medication mustn't be stopped suddenly without talking to the doctor as it may result in a worsening of symptoms.

Some common side effects of this medicine include nausea, vomiting, constipation, and blurred vision. It even causes dizziness and sleepiness, so do not drive or do anything that requires mental focus until you know how this medicine affects you. Dry mouth may occur commonly while using this medicine so, try to do frequent mouth rinses, maintain good oral hygiene, and increase water intake. Avoid wearing contact lenses as it may cause dry eyes as well. It is important to inform your doctor if you suffer from glaucoma or have trouble passing urine.

Before using Trihexol Forte Tablet, you should tell your doctor if you've ever had heart problems, problems with passing urine, liver or kidney disease. It may also affect, or be affected by, some other drugs you are using so let your doctor know what these are to be safe. Pregnant or breastfeeding mothers should consult their doctor before starting treatment with this medicine.

Uses of Trihexol Tablet

Benefits of Trihexol Tablet

Treatment of Parkinson's disease
Parkinson’s disease (PD) is a disorder of the central nervous system. It makes the muscles stiff which causes difficulties in standing and walking. PD also causes tremors and loss of balance. Trihexol Forte Tablet helps to treat the symptoms of Parkinson's Disease. It relaxes the stiff muscles and helps in easy movement without losing balance. Trihexol Forte Tablet is also used to treat side effects like abnormal movements caused by antipsychotic drugs.

It is advisable not to stop this medicine without consulting your doctor. This is because a sudden stoppage can cause symptoms of Parkinson's disease to return. You can see that the drug is working if you are able to do your daily activities more easily and have a more active and better quality of life.
Treatment of Drug induced abnormal movements
Trihexol Forte Tablet is also used to treat side effects like abnormal movements caused by antipsychotic drugs. It helps restore normal body posture as well as control over muscle movements in the body. This will enable you to lead a normal life and improve your ability to carry out daily activities.

Side effects of Trihexol Tablet

Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them
Common side effects of Trihexol
  • Nausea
  • Vomiting
  • Constipation
  • Blurred vision

How to use Trihexol Tablet

Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Trihexol Forte Tablet is to be taken empty stomach.

How Trihexol Tablet works

Trihexol Forte Tablet is an anticholinergic medication. It works by decreasing the activity of a chemical messenger (acetylcholine) in the brain. This improves muscle control and reduces stiffness in Parkinson's disease. It also improves movement disorder (restlessness, involuntary movements or muscle spasm) caused by certain other medicines.

All substitutes for Trihexol Forte Tablet

For information purposes only. Consult a doctor before taking any medicine.

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Quick tips

  • Dry mouth may occur as a side effect. Frequent mouth rinses, good oral hygiene, increased water intake and sugarless candy may help.
  • It may cause dry eyes. Avoid wearing contact lenses and inform your doctor if it bothers you.
  • It may cause dizziness and sleepiness. Do not drive or do anything requiring concentration until you know how it affects you.
  • Monitoring of intraocular pressure is required while taking this medicine, as an increase in eye pressure may cause blurry vision.
  • Inform your doctor if you suffer from  glaucoma or if you have trouble passing urine.

Safety advice

Alcohol

Alcohol

UNSAFE
Trihexol Forte Tablet may cause excessive drowsiness with alcohol.
Pregnancy

Pregnancy

CONSULT YOUR DOCTOR
Trihexol Forte Tablet may be unsafe to use during pregnancy. Although there are limited studies in humans, animal studies have shown harmful effects on the developing baby. Your doctor will weigh the benefits and any potential risks before prescribing it to you. Please consult your doctor.
Breast feeding

Breast feeding

CONSULT YOUR DOCTOR
Trihexol Forte Tablet is probably unsafe to use during breastfeeding. Limited human data suggests that the drug may pass into the breastmilk and harm the baby.
Driving

Driving

UNSAFE
Trihexol Forte Tablet may decrease alertness, affect your vision or make you feel sleepy and dizzy. Do not drive if these symptoms occur.
Trihexol Forte Tablet can cause blurring of vision, dizziness, mild nausea, and mental confusion in some cases. This may affect your ability to drive.
Kidney

Kidney

CONSULT YOUR DOCTOR
There is limited information available on the use of Trihexol Forte Tablet in patients with kidney disease. Please consult your doctor.
Patients with kidney disease should be closely monitored by a doctor while taking this medicine.
Liver

Liver

CONSULT YOUR DOCTOR
There is limited information available on the use of Trihexol Forte Tablet in patients with liver disease. Please consult your doctor.
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Frequently asked questions

No, Trihexol Forte Tablet is not a narcotic. However, its hallucinogenic and euphoriant properties may make the people abuse its use.
Yes, Trihexol Forte Tablet may cause drowsiness in some cases. Some people may even experience difficulty in falling asleep. Do not drive or operate heavy machinery when you experience drowsiness or if it causes blurring of vision, dizziness, mild nausea and mental confusion.
Taking more than the recommended doses of Trihexol Forte Tablet may cause flushing of the skin, nausea, vomiting, dilated pupils, increased heartbeat, rapid respiration, fever, increase in blood pressure, and dryness of mouth, tongue and skin. A rash may appear on the face or upper trunk. You may also experience restlessness, confusion, hallucinations, paranoid and psychotic reactions, incoordination, delirium (a state of mental confusion and emotional disruption) and occasionally convulsions.
No, Trihexol Forte Tablet should not be crushed. It should be swallowed as a whole with a glass of water. Consult your doctor if you are not sure about how to take this medicine.
Trihexol Forte Tablet may be taken before or after meals according to the effects experienced by the patient. If Trihexol Forte Tablet tends to dry the mouth excessively, it may be better to take it before meals, unless it causes nausea. If taken after meals, it may cause induced thirst which can be reduced by peppermint, chewing gum, or water.
You should continue taking Trihexol Forte Tablet as long as your doctor advises you. In some cases, the use of Trihexol Forte Tablet may continue indefinitely. Such patients are often kept under careful observation for a longer period of time.
You should not stop taking Trihexol Forte Tablet without consulting your doctor as your symptoms may get worse. If you feel your dose needs to be lowered, then consult your doctor who will reduce your dose gradually.
No, Trihexol Forte Tablet is not a narcotic. However, its hallucinogenic and euphoriant properties may make the people abuse its use.
Yes, Trihexol Forte Tablet may cause drowsiness in some cases. Some people may even experience difficulty in falling asleep. Do not drive or operate heavy machinery when you experience drowsiness or if it causes blurring of vision, dizziness, mild nausea and mental confusion.
Taking more than the recommended doses of Trihexol Forte Tablet may cause flushing of the skin, nausea, vomiting, dilated pupils, increased heartbeat, rapid respiration, fever, increase in blood pressure, and dryness of mouth, tongue and skin. A rash may appear on the face or upper trunk. You may also experience restlessness, confusion, hallucinations, paranoid and psychotic reactions, incoordination, delirium (a state of mental confusion and emotional disruption) and occasionally convulsions.
Yes, Trihexol Forte Tablet may cause weight gain. If you are concerned about your weight gain, consult a dietician for diet plan, exercise regularly, and eat a healthy and nutritious diet.
No, Trihexol Forte Tablet should not be crushed. It should be swallowed as a whole with a glass of water. Consult your doctor if you are not sure about how to take this medicine.
Trihexol Forte Tablet may be taken before or after meals according to the effects experienced by the patient. If Trihexol Forte Tablet tends to dry the mouth excessively, it may be better to take it before meals, unless it causes nausea. If taken after meals, it may cause induced thirst which can be reduced by peppermint, chewing gum, or water.
You should continue taking Trihexol Forte Tablet as long as your doctor advises you. In some cases, the use of Trihexol Forte Tablet may continue indefinitely. Such patients are often kept under careful observation for a longer period of time.
You should not stop taking Trihexol Forte Tablet without consulting your doctor as your symptoms may get worse. If you feel your dose needs to be lowered, then consult your doctor who will reduce your dose gradually.

Fact Box

Chemical Class

Aralkylamines Derivative

Habit Forming

No

Therapeutic Class

NEURO CNS

Action Class

Anticholinergic- centrally acting

References

  1. Stahl SM, editor. Trihexyphenidyl. In: Stahl's Essential Pschopharmacology: Prescriber's Guide. 5th ed. New York, New York: Cambridge University Press; 2014. pp. 697-99.
  2. Briggs GG, Freeman RK, editors. A Reference Guide to Fetal and Neonatal Risk: Drugs in Pregnancy and Lactation. 10th ed. Philadelphia, PA: Wolters Kluwer Health; 2015. p. 1405.
  3. Trihexyphnidyl. Huddersfield, West Yorkshire: Genus Pharmaceuticals; 2011 [revised 18 Dec. 2018]. [Accessed 19 Mar. 2019] (online) Available from:
  4. Jilani TN, Sharma S. Trihexyphenidyl. [Internet]. Treasure Island, Florida: StatPearls Publishing; 2019. [Accessed 20 Jun. 2019] (online) Available from:
  5. Drugs and Lactation Database (LactMed) [Internet]. Bethesda (MD): National Library of Medicine (US); 2006. Trihexyphenidyl. [Updated 2018 Dec 3]. [Accessed 20 Feb. 2020] (online) Available from:
  6. Central Drugs Standard Control Organisation (CDSCO). [Accessed 19 Mar. 2019] (online) Available from:
  7. Trihexyphenidyl HCl [Product Information]. Kothur, AP: Natco Pharma Limited; 2019. [Accessed 25 Jul. 2024] (online) Available from:
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Patient concerns

Parkinson's disease tremors ,Insomnia.

Dr. Ravi Shankar M.
Dr. Ravi Shankar M.
Ayurveda
Use Dhanadanayanadi kashayam 15ml twice a day with 15 ml water before food and Zandopa 10 grams twice a day witk milk after food and Tab Dhanvantari Vati 1-0-1 after food for 2 months

Useing sindopa tab 2 each four times a day have any side effect

Dr. Vikas Sharma
Dr. Vikas Sharma
Neurology
yes it can sometimes cause abnormal movements with prolonged use
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Tata 1mg's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover everything about particular health conditions, lab tests, medicines, all possible side effects, drug interactions, warnings, alerts, etc. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.

Marketer details

Name: Chicky Pharma Pvt Ltd
Address: Chicky Pharma Private Limited, Gel Church Complex Gr Flr Opp, A C Mkt Eastern Side Main Rd, Ranchi-834001, Jharkhand, India

Vendor Details

Country of origin: India

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