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Tysabri 300mg Injection
Natalizumab (20mg/ml)
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Tysabri 300mg Injection is used in the treatment of multiple sclerosis (MS). It may be also used to treat other conditions, as determined by the doctor.
Written By Dr. Anuj Saini, MMST, MBBS,
Reviewed By Dr. Varun Gupta, MD Pharmacology, MBBS,
Last updated on 11 Nov 2024 | 01:04 AM (IST)
Written By Dr. Anuj Saini, MMST, MBBS,
Reviewed By Dr. Varun Gupta, MD Pharmacology, MBBS,
Last updated on 11 Nov 2024 | 01:04 AM (IST)
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15 ml Injection
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General Information
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Product introduction
Tysabri 300mg Injection stops the cells that cause inflammation from going into your brain. This reduces nerve damage caused by MS. This medicine often causes nausea and vomiting. However, it is important that you continue to receive the medicine, even if you begin to feel ill. Do not stop taking this medicine without first checking with your doctor. Inform your doctor if you develop symptoms like abdominal pain, loss of appetite, darkened urine or yellowing of the eyes or skin. These may be the signs liver damage.
This medicine may reduce the number of blood cells in your blood thereby, increasing the susceptibility to infections. Regular blood tests are required to check your blood cells along with kidney, liver and heart function during treatment with this medicine. It is important to use effective contraception to avoid getting pregnant or fathering a child during treatment. The duration of the treatment with this medicine is decided by your doctor depending upon your disease.
This medicine may reduce the number of blood cells in your blood thereby, increasing the susceptibility to infections. Regular blood tests are required to check your blood cells along with kidney, liver and heart function during treatment with this medicine. It is important to use effective contraception to avoid getting pregnant or fathering a child during treatment. The duration of the treatment with this medicine is decided by your doctor depending upon your disease.
Uses of Tysabri Injection
Benefits of Tysabri Injection
Multiple sclerosis (MS)
Multiple sclerosis (MS) is a disease of the brain and spinal cord in which a person’s own immune system attacks the protective sheath (called myelin) of the nerves. This leads to symptoms such as vision loss, pain, fatigue and improper coordination. Tysabri 300mg Injection helps to suppress the body’s immune system, thereby reducing the progression of the disease. It reduces the inflammation of the damaged nerves, prevents further damage and stabilises your immune system. It improves muscle strength and helps the patients to walk better. This makes the patients more confident and enhances their quality of life.
Multiple sclerosis (MS) is a disease of the brain and spinal cord in which a person’s own immune system attacks the protective sheath (called myelin) of the nerves. This leads to symptoms such as vision loss, pain, fatigue and improper coordination. Tysabri 300mg Injection helps to suppress the body’s immune system, thereby reducing the progression of the disease. It reduces the inflammation of the damaged nerves, prevents further damage and stabilises your immune system. It improves muscle strength and helps the patients to walk better. This makes the patients more confident and enhances their quality of life.
Side effects of Tysabri Injection
Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them
Common side effects of Tysabri
- Depression
- Diarrhea
- Headache
- Joint pain
- Lung infection
- Pain in extremities
- Rash
- Stomach pain
- Throat infection
- Tiredness
- Urinary tract infection
- Vaginal inflammation
How to use Tysabri Injection
Your doctor or nurse will give you this medicine. Kindly do not self administer.
How Tysabri Injection works
Certain immune cells (T cells) are known to attack the protective sheath (myelin) around the nerves and cause disabling effects in multiple sclerosis. Tysabri 300mg Injection works by binding to T cells and preventing their entry into the brain and spinal cord. This slows disease progression and reduces the number of attacks in multiple sclerosis.
Quick tips
- Tysabri 300mg Injection is used to treat multiple sclerosis.
- It is given once every 4 weeks, as a drip into a vein (by intravenous infusion), usually in your arm.
- It may increase your risk of getting infections. Inform your doctor immediately if you get any signs of infection such as fever, sore throat, mouth ulcers, rash or severe diarrhea while taking this medicine.
- Inform your doctor if you develop symptoms of liver damage such as abdominal pain, loss of appetite, darkened urine or yellowing of the eyes or skin.
- Do not stop treatment without talking to your doctor. You are more likely to experience an allergic reaction if you restart treatment after a gap of three or more months.
Safety advice

Alcohol
CONSULT YOUR DOCTOR
It is not known whether it is safe to consume alcohol with Tysabri 300mg Injection. Please consult your doctor.

Pregnancy
CONSULT YOUR DOCTOR
Tysabri 300mg Injection may be unsafe to use during pregnancy. Although there are limited studies in humans, animal studies have shown harmful effects on the developing baby. Your doctor will weigh the benefits and any potential risks before prescribing it to you. Please consult your doctor.

Breast feeding
CONSULT YOUR DOCTOR
Information regarding the use of Tysabri 300mg Injection during breastfeeding is not available. Please consult your doctor.

Driving
UNSAFE
Tysabri 300mg Injection may decrease alertness, affect your vision or make you feel sleepy and dizzy. Do not drive if these symptoms occur.

Kidney
CONSULT YOUR DOCTOR
There is limited information available on the use of Tysabri 300mg Injection in patients with kidney disease. Please consult your doctor.

Liver
CONSULT YOUR DOCTOR
There is limited information available on the use of Tysabri 300mg Injection in patients with liver disease. Please consult your doctor.
Fact Box
Chemical Class
Humanized IgG4k monoclonal antibody
Habit Forming
No
Therapeutic Class
ANTI NEOPLASTICS
Action Class
Alpha-4 integrin inhibitor
References
- Briggs GG, Freeman RK, editors. A Reference Guide to Fetal and Neonatal Risk: Drugs in Pregnancy and Lactation. 10th ed. Philadelphia, PA: Wolters Kluwer Health; 2015. pp. 959-61.
- MS Society. Natalizumab. [Accessed 21 Jan. 2019] (online) Available from:
- Tysabri. Natalizumab. [Accessed 26 Mar. 2019] (online) Available from:
- Natalizumab. Cambridge, Massachusetts: Biogen Idec Inc.; 2004 [revised Jan. 2012]. [Accessed 26 Mar. 2019] (online) Available from:
- Natalizumab. Maidenhead, Berkshire: Biogen Idec Ltd; 2006 [revised Aug. 2018]. [Accessed 26 Mar. 2019] (online) Available from:
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Tata 1mg's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover everything about particular health conditions, lab tests, medicines, all possible side effects, drug interactions, warnings, alerts, etc. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.
Marketer details
Name: Biogen Idec Biotech India Pvt Ltd
Address: A-1/292, Ground Floor Janak Puri New Delhi West Delhi DL 110058 IN
Address: A-1/292, Ground Floor Janak Puri New Delhi West Delhi DL 110058 IN
Vendor Details
Country of origin: India
A licensed vendor partner from your nearest location will deliver Tysabri 300mg Injection. Once the pharmacy accepts your order, the details of the pharmacy will be shared with you. Acceptance of your order is based on the validity of your doctor's ℞ and the availability of this medicine.
Phone Number: 0124-4166666
Address: 5th Floor Tower - B of the Presidency Building, 46/4 Mehrauli Gurgaon Road, Sector 14, Gurugram, Haryana-122001, India
A licensed vendor partner from your nearest location will deliver Tysabri 300mg Injection. Once the pharmacy accepts your order, the details of the pharmacy will be shared with you. Acceptance of your order is based on the validity of your doctor's ℞ and the availability of this medicine.
In case of any issues, contact us
Email ID: [email protected]Phone Number: 0124-4166666
Address: 5th Floor Tower - B of the Presidency Building, 46/4 Mehrauli Gurgaon Road, Sector 14, Gurugram, Haryana-122001, India
Lab tests offered by us
- CBC (Complete Blood Count)
- FBS (Fasting Blood Sugar)
- Thyroid Profile Total (T3, T4 & TSH)
- HbA1c (Glycosylated Hemoglobin)
- Glucose - Postprandial
- Lipid Profile
- Vitamin D (25-Hydroxy)
- Urine R/M (Urine Routine & Microscopy)
- Coronavirus Covid-19 Test (RT-PCR technique)
- LFT (Liver Function Test)
- Kidney Function Test
- TSH (Thyroid Stimulating Hormone) Ultrasensitive
- ESR (Erythrocyte Sedimentation Rate)
- Uric Acid
- Vitamin B12
- C- Reactive Protein Quantitative
- Urine Culture and Sensitivity
- Serum Electrolyte
- Serum Calcium
- Creatinine
- Diabetes Screening
- KFT with Electrolytes (Kidney Function Test with Electrolytes)
- Cholesterol - Total
- Hemoglobin
- Complete Haemogram
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