
Uroprase 500000IU Injection
Written By Dr. Anuj Saini, MMST, MBBS
Reviewed By Dr. Varun Gupta, MD Pharmacology, MBBS
Last updated on 08 Nov 2024 | 11:12 AM (IST)
Uroprase 500000IU Injection is a medicine used to break down harmful blood clots that have formed in the blood vessels. It is used to treat patients who have suffered a recent heart attack. It is also used in treating conditions such as pulmonary embolism and stroke.
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General Information
Contains
Urokinase (500000IU)
Marketer
Chandra Bhagat Pharma Pvt Ltd
Storage
Store in a refrigerator (2 - 8°C). Do not freeze.
The content is shown in English



Product introduction
Uroprase 500000IU Injection is administered under the supervision of a doctor. Your doctor will decide the dose and duration of the medicine for you. The doctor may closely monitor your condition until you become stable.
Use of this medicine may cause nausea, vomiting, injection site bleeding, allergic reaction, and a decrease in blood pressure. It may increase your risk of bleeding also. Your doctor will explain the benefits and risks associated with this medicine before it is administered. You should continue all your other medicines that are advised by the doctor for your long-term treatment even after this injection.
This medicine is used with caution for some people. Thus, you must inform the doctor if you are suffering from any bleeding disorder, kidney, or liver disease. Also, let your doctor know if you are pregnant or breastfeeding and about all the other medications that you are taking regularly.
Use of this medicine may cause nausea, vomiting, injection site bleeding, allergic reaction, and a decrease in blood pressure. It may increase your risk of bleeding also. Your doctor will explain the benefits and risks associated with this medicine before it is administered. You should continue all your other medicines that are advised by the doctor for your long-term treatment even after this injection.
This medicine is used with caution for some people. Thus, you must inform the doctor if you are suffering from any bleeding disorder, kidney, or liver disease. Also, let your doctor know if you are pregnant or breastfeeding and about all the other medications that you are taking regularly.
Uses of Uroprase Injection
Side effects of Uroprase Injection
Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them
Common side effects of Uroprase
- Allergic reaction
- Nausea
- Vomiting
- Injection site bleeding
- Decreased blood pressure
How to use Uroprase Injection
Your doctor or nurse will give you this medicine. Kindly do not self administer.
How Uroprase Injection works
Uroprase 500000IU Injection works by dissolving the harmful blood clots in the blood vessels. This restores the blood flow to the affected tissue, thereby preventing tissue death and improving outcomes.
All substitutes for Uroprase 500000IU Injection
For information purposes only. Consult a doctor before taking any medicine.
U Frag 500000IU Injection
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Urokinase 500000IU Injection
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Solokinase 500000IU Injection
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₹3600.79/injection
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Medinase 500000IU Injection
by Life Medicare & Biotech Pvt Ltd
₹3428.57/injection
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Renokinase 500000IU Injection
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₹1752.38/injection
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Quick tips
- It increases your risk of bleeding. Be careful while shaving, cutting fingernails or toenails, using sharp objects or engaging in contact sports (e.g. football, wrestling).
- Do not discontinue use without consulting your doctor as this may increase your chances of having another heart attack or stroke.
- Uroprase 500000IU Injection helps break down blood clots in blood vessels, thereby treating conditions such as heart attack, pulmonary embolism, and stroke.
- It should be given as soon as possible (within 12 hours) after the onset of a heart attack.
- It is usually given by your nurse or doctor as an infusion (drip) into a vein.
- It increases your risk of bleeding. Be careful while shaving, cutting fingernails or toenails, using sharp objects or engaging in contact sports (e.g. football, wrestling).
- Do not discontinue use without consulting your doctor as this may increase your chances of having another heart attack or stroke.
Safety advice

Alcohol
CONSULT YOUR DOCTOR
It is not known whether it is safe to consume alcohol with Uroprase 500000IU Injection. Please consult your doctor.

Pregnancy
SAFE IF PRESCRIBED
Uroprase 500000IU Injection is generally considered safe to use during pregnancy. Animal studies have shown low or no adverse effects to the developing baby; however, there are limited human studies.

Breast feeding
SAFE IF PRESCRIBED
Uroprase 500000IU Injection is probably safe to use during breastfeeding. Limited human data suggests that the drug does not represent any significant risk to the baby.

Driving
NOT RELEVANT
Not relevant, as Uroprase 500000IU Injection is intended for use in hospitalised patients.

Kidney
SAFE IF PRESCRIBED
Uroprase 500000IU Injection is probably safe to use in patients with kidney disease. Limited data available suggests that dose adjustment of Uroprase 500000IU Injection may not be needed in these patients. Please consult your doctor.
Use of Uroprase 500000IU Injection is not recommended in patients with severe kidney disease.
Use of Uroprase 500000IU Injection is not recommended in patients with severe kidney disease.

Liver
CAUTION
Uroprase 500000IU Injection should be used with caution in patients with liver disease. Dose adjustment of Uroprase 500000IU Injection may be needed. Please consult your doctor.
Frequently asked questions
Yes, Uroprase 500000IU Injection increases the risk of bleeding. Always be careful while doing activities that may cause an injury or bleeding. Tell your doctor immediately if you notice any abnormal bruising or bleeding.
Uroprase 500000IU Injection can interact with several medicines. Do not take any medicine without talking to your doctor.
Fact Box
Chemical Class
Amino acids, Peptides analogues
Habit Forming
No
Therapeutic Class
CARDIAC
Action Class
First-Generation Thrombolytics
Related lab tests
References
- Briggs GG, Freeman RK, editors. A Reference Guide to Fetal and Neonatal Risk: Drugs in Pregnancy and Lactation. 10th ed. Philadelphia, PA: Wolters Kluwer Health; 2015. pp. 1414-5.
- Central Drugs Standard Control Organisation (CDSCO). [Accessed 19 Mar. 2019] (online) Available from:
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Tata 1mg's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover everything about particular health conditions, lab tests, medicines, all possible side effects, drug interactions, warnings, alerts, etc. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.
Marketer details
Name: Chandra Bhagat Pharma Pvt Ltd
Address: 501, The Bureau, R C MARG, Nr.Chembur Naka, Chembur East, Mumbai - 400071
Address: 501, The Bureau, R C MARG, Nr.Chembur Naka, Chembur East, Mumbai - 400071
Vendor Details
Country of origin: India
Lab tests offered by us
- CBC (Complete Blood Count)
- FBS (Fasting Blood Sugar)
- Thyroid Profile Total (T3, T4 & TSH)
- HbA1c (Glycosylated Hemoglobin)
- Glucose - Postprandial
- Lipid Profile
- Vitamin D (25-Hydroxy)
- Urine R/M (Urine Routine & Microscopy)
- Coronavirus Covid-19 Test (RT-PCR technique)
- LFT (Liver Function Test)
- Kidney Function Test
- TSH (Thyroid Stimulating Hormone) Ultrasensitive
- ESR (Erythrocyte Sedimentation Rate)
- Uric Acid
- Vitamin B12
- C- Reactive Protein Quantitative
- Urine Culture and Sensitivity
- Serum Electrolyte
- Serum Calcium
- Creatinine
- Diabetes Screening
- KFT with Electrolytes (Kidney Function Test with Electrolytes)
- Cholesterol - Total
- Hemoglobin
- Complete Haemogram
Why we need a prescription?
Provide right medicines
Prescriptions are complex documents. We proof read and recheck at various steps to provide you the right medication in the correct form and dose
In accordance with the law
Most medicines cannot be sold without a valid prescription, as per the Drugs and Cosmetics Act, 1940 and Rules, 1945














