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Vancomycin 500mg Injection

Written By Dr. Love Sharma, PhD (Pharmacology), PGDPRA
Reviewed By Dr. Varun Gupta, MD Pharmacology, MBBS
Last updated on 12 Nov 2024 | 01:01 AM (IST)
Vancomycin 500mg Injection is an antibiotic used in the treatment of severe bacterial infections in hospitalized patients. It is effective against infections of the respiratory tract (e.g. pneumonia), urinary tract, skin and soft tissues, bones and joints, heart, blood, and others.
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General Information

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Vancomycin 500mg Injection image

Product introduction

Vancomycin 500mg Injection is also used for the prevention of infection in some high-risk patients undergoing surgical procedures. It works by stopping the growth of bacteria and is useful for treating adults as well as children. It is a narrow-spectrum antibiotic that only covers the gram-positive type of bacteria. This medicine is administered slowly by a drip (infusion) into a vein, under the supervision of a healthcare professional. A rapid infusion can lead to reactions such as low blood pressure, wheezing, shortness of breath, or itching. It may also be combined with other antibiotics to treat additional types of bacteria.

Some people may develop local injection site reactions like pain, swelling, and redness. However, these are usually minor and temporary. Other side effects like wheezing, kidney (renal) injury, shortness of breath, flushing (sense of warmth in the face, ears, neck, and trunk) and decreased blood pressure may be seen occasionally.

Inform your doctor if you have a history of an allergic reaction to this medication in the past. Your doctor may regularly monitor your kidney function and your hearing while you are taking this medicine. Some people may be advised blood tests to check the level of this medicine in their blood. Consult your doctor if you are pregnant or breastfeeding before taking this medicine.

Uses of Vancomycin Injection

  • Severe bacterial infections

Benefits of Vancomycin Injection

Severe bacterial infections
Vancomycin 500mg Injection works by killing bacteria which can cause serious infections. It is used to treat many different types of bacterial infections such as infections of the lungs (pneumonia) and urinary tract. It is given by a doctor or nurse into a vein and should not be self-administered. Vancomycin 500mg Injection usually makes you feel better very quickly but you should continue taking it as prescribed even when you feel better to make sure that all bacteria are killed and do not become resistant.

Side effects of Vancomycin Injection

Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them
Common side effects of Vancomycin
  • Breathlessness
  • Vomiting
  • Nausea
  • Decreased potassium level in blood
  • Abdominal pain
  • Decreased white blood cell count (neutrophils)
  • Phlebitis
  • Hypotension (low blood pressure)
  • Flatulence
  • Hearing loss
  • Renal toxicity
  • Headache
  • Fever
  • Peripheral edema
  • Fatigue
  • Urinary tract infection
  • Back pain
  • Red man syndrome

How to use Vancomycin Injection

Your doctor or nurse will give you this medicine. Kindly do not self administer.

How Vancomycin Injection works

Vancomycin 500mg Injection is an antibiotic. It kills bacteria by preventing them from forming the bacterial protective covering (cell wall) which is needed for them to survive.

Quick tips

  • You  have been prescribed Vancomycin 500mg Injection to treat serious bacterial infections of the heart, blood, bones, and soft tissues.
  • Do not skip any doses and finish the full course of treatment even if you feel better. Stopping it early may make the infection to come back and harder to treat.
  • It should be taken slowly via a drip. Fast infusion can lead to reactions such as low blood pressure, wheezing, shortness of breath or itching.
  • Your doctor may regularly monitor your kidney function and your hearing while you are taking this medicine.
  • Your doctor may get regular blood tests done to check the level of this medicine in your blood.
  • Inform your doctor if you are pregnant, planning to conceive, or breastfeeding.

Safety advice

Alcohol

Alcohol

SAFE
Consuming alcohol with Vancomycin 500mg Injection does not cause any harmful side effects.
Pregnancy

Pregnancy

CONSULT YOUR DOCTOR
Vancomycin 500mg Injection may be unsafe to use during pregnancy. Although there are limited studies in humans, animal studies have shown harmful effects on the developing baby. Your doctor will weigh the benefits and any potential risks before prescribing it to you. Please consult your doctor.
Breast feeding

Breast feeding

SAFE IF PRESCRIBED
Vancomycin 500mg Injection is probably safe to use during breastfeeding. Limited human data suggests that the drug does not represent any significant risk to the baby.
Driving

Driving

SAFE
Vancomycin 500mg Injection does not usually affect your ability to drive.
Kidney

Kidney

CAUTION
Vancomycin 500mg Injection should be used with caution in patients with kidney disease. Dose adjustment of Vancomycin 500mg Injection may be needed. Please consult your doctor.
Regular monitoring of kidney function test and some blood tests is advised while you are taking this medicine.
Liver

Liver

CONSULT YOUR DOCTOR
There is limited information available on the use of Vancomycin 500mg Injection in patients with liver disease. Please consult your doctor.
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Frequently asked questions

Usually, Vancomycin 500mg Injection starts working soon after taking it. However, it may take some days to kill all the harmful bacteria and make you feel better.

Fact Box

Chemical Class

Glycopeptides

Habit Forming

No

Therapeutic Class

ANTI INFECTIVES

Action Class

Glycopeptides

Related lab tests

References

  1. MacDougall C, Chambers HF. Protein Synthesis Inhibitors and Miscellaneous Antibacterial Agents. In: Brunton LL, Chabner BA, Knollmann BC, editors. Goodman & Gilman’s: The Pharmacological Basis of Therapeutics. 12th ed. New York, New York: McGraw-Hill Medical; 2011. pp. 1539-42.
  2. Chambers HF, Deck DH. Beta-Lactam and Other Cell Wall- & Membrane-Active Antibiotics. In: Katzung BG, Masters SB, Trevor AJ, editors. Basic and Clinical Pharmacology. 11th ed. New Delhi, India: Tata McGraw Hill Education Private Limited; 2009. pp. 786-87.
  3. Briggs GG, Freeman RK, editors. A Reference Guide to Fetal and Neonatal Risk: Drugs in Pregnancy and Lactation. 10th ed. Philadelphia, PA: Wolters Kluwer Health; 2015. pp. 1459-60.
  4. ScienceDirect. Vancomycin. [Accessed on 26 Mar. 2019] (online) Available from:
  5. Vancomycin. Deerfield, IL: Baxter Healthcare Corporation; 2008. [Accessed 28 Mar. 2019] (online) Available from:
  6. Central Drugs Standard Control Organisation (CDSCO). [Accessed 28 Mar. 2019] (online) Available from:
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User feedback

Once A Week
36%
Once A Day
29%
Twice A Day
14%
Once A Month
14%
Twice A Month
7%
Serious bacterial infections
100%

Patient concerns

THR surgery done 10 years back & implant removed due to mess infection . Now that infection could not be healed after taking vancomycin injection iv duly culture test.

Dr. Trilok Kumar Jha
Dr. Trilok Kumar Jha
Orthopaedics
You show to some good. Joint replacement. Surgeon.

Scar on face due to bacterial infections

Dr. Atul Jain
Dr. Atul Jain
Dermatology
Pic is not clear, plz visit for proper opinion
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Disclaimer

Tata 1mg's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover everything about particular health conditions, lab tests, medicines, all possible side effects, drug interactions, warnings, alerts, etc. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.

Marketer details

Name: AstraZeneca
Address: Corporate & Registered Office, Block N1, 12th Floor, Manyata Embassy Business Park, Rachenahalli, Outer Ring Road, 560045, Bangalore

Vendor Details

Country of origin: India
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