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Virolfi 450mg Tablet

Written By Dr. Sakshi Sharma, BDS
Reviewed By Dr. Lalit Kanodia, MBA, MD Pharmacology
Last updated on 12 Nov 2024 | 01:04 AM (IST)
Virolfi 450mg Tablet is used to treat cytomegalovirus (CMV) infection of the retina (retinitis) in adult patients with acquired immunodeficiency syndrome (AIDS). It is also used for the prevention of CMV infection in patients who have received an organ transplant from a CMV-infected donor.
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General Information

Contains

Valganciclovir (450mg)

Marketer

Zydus Cadila

Storage

Store below 30°C
The content is shown in English
Virolfi 450mg Tablet image

Product introduction

Virolfi 450mg Tablet should be taken in the dose and duration as advised by your doctor. Do not skip any doses and finish the full course of treatment even if you feel better. It should be taken with food. If you miss a dose, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your regular schedule. Do not double the dose. You should drink plenty of water while on treatment with this medicine as it helps to prevent dehydration and kidney damage.

It may lead to a few common side effects like fever, diarrhea, vomiting, anemia, low white blood cell, and low platelet level. Inform your doctor if these side effects persist for a longer duration. Please consult your doctor if you are pregnant, planning to conceive or breastfeeding.

Uses of Virolfi Tablet

  • Treatment of Cytomegalovirus Infection

Benefits of Virolfi Tablet

Treatment of Cytomegalovirus Infection
Cytomegalovirus infection is a common virus infection which may have no symptoms at all or may have symptoms like fever and fatigue. Severe infection may show symptoms involving the eyes, brain, or other internal organs. This virus is spread through sexual and nonsexual contact with body secretions in people who are immunocompromised or those who have undergone any transplant. Virolfi 450mg Tablet helps to prevent multiplication of the infection causing virus and treats the infection. Keep taking it in the dose and duration prescribed by the doctor to get maximum benefit.

Side effects of Virolfi Tablet

Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them
Common side effects of Virolfi
  • Diarrhea
  • Fever
  • Vomiting
  • Anemia (low number of red blood cells)
  • Decreased white blood cell count
  • Low blood platelets
  • Insomnia (difficulty in sleeping)
  • Tremors

How to use Virolfi Tablet

Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Virolfi 450mg Tablet is to be taken with food.

How Virolfi Tablet works

Virolfi 450mg Tablet is an antiviral medication. It prevents the multiplication of virus in human cells. This stops the virus from producing new viruses and clears up your infection.

All substitutes for Virolfi 450mg Tablet

For information purposes only. Consult a doctor before taking any medicine.

Valgan Tablet

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Valchek Tablet

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Cmvee 450mg Tablet

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Valstead 450mg Tablet

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₹400/tablet
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Safety advice

Alcohol

Alcohol

CONSULT YOUR DOCTOR
It is not known whether it is safe to consume alcohol with Virolfi 450mg Tablet. Please consult your doctor.
Pregnancy

Pregnancy

CONSULT YOUR DOCTOR
Virolfi 450mg Tablet may be unsafe to use during pregnancy. Although there are limited studies in humans, animal studies have shown harmful effects on the developing baby. Your doctor will weigh the benefits and any potential risks before prescribing it to you. Please consult your doctor.
Breast feeding

Breast feeding

CONSULT YOUR DOCTOR
Virolfi 450mg Tablet is probably unsafe to use during breastfeeding. Limited human data suggests that the drug may pass into the breastmilk and harm the baby.
Driving

Driving

UNSAFE
Virolfi 450mg Tablet may decrease alertness, affect your vision or make you feel sleepy and dizzy. Do not drive if these symptoms occur.
Kidney

Kidney

CAUTION
Virolfi 450mg Tablet should be used with caution in patients with kidney disease. Dose adjustment of Virolfi 450mg Tablet may be needed. Please consult your doctor.
Liver

Liver

SAFE IF PRESCRIBED
Virolfi 450mg Tablet is probably safe to use in patients with liver disease. Limited data available suggests that dose adjustment of Virolfi 450mg Tablet may not be needed in these patients. Please consult your doctor.
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Frequently asked questions

Valganciclovir is used for the treatment of cytomegalovirus (CMV) infection of retina (retinitis) in adult patients with acquired immunodeficiency syndrome (AIDS). It is also used for the prevention of CMV infection in patients who have received an organ transplant from a CMV-infected donor
After taken orally, valganciclovir gets converted into ganciclovir by liver and intestinal enzymes, which then prevents the growth and spread of cytomegalovirus.
No, valganciclovir is not cytotoxic
Valganciclovir can also be used for treatment of herpes simplex virus (HSV) infection. Please follow doctor's advice regarding its use

Fact Box

Chemical Class

Nucleoside analog

Habit Forming

No

Therapeutic Class

ANTI INFECTIVES

Action Class

Antiviral (Non-HIV) drugs

References

  1. Acosta EP, Flexner C. Antiviral Agents (Nonretroviral). In: Brunton LL, Chabner BA, Knollmann BC, editors. Goodman & Gilman’s: The Pharmacological Basis of Therapeutics. New York, New York: McGraw-Hill Medical; 2011. pp. 1603-605.
  2. Safrin S. Antiviral Agents. In: Katzung BG, Masters SB, Trevor AJ, editors. Basic and Clinical Pharmacology. 11th ed. New Delhi, India: Tata McGraw Hill Education Private Limited; 2009. p. 852.
  3. Briggs GG, Freeman RK, editors. A Reference Guide to Fetal and Neonatal Risk: Drugs in Pregnancy and Lactation. 10th ed. Philadelphia, PA: Wolters Kluwer Health; 2015. pp. 1446-47.
  4. Valgaciclovir. Grenzach-Wyhlen, Germany: Roche Pharma; 2018. [Accessed 01 Apr. 2019] (online) Available from:
  5. Valganciclovir hydrochloride. Garden City, Hertfordshire: Roche Products Limited; 2002 [revised 16 May 2018]. [Accessed 28 Jan. 2019] (online) Available from:
  6. Valganciclovir. South san Francisco, California: Genentech USA; 2001 [revised Aug. 2010]. [Accessed 01 Apr. 2019] (online) Available from:
  7. CiplaMed. Valganciclovir [Prescribing Information]. [Accessed 07 Aug. 2023]. (online) Available from:
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User feedback

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Patient concerns

i have unprotected sex with my friend. Can I take any drugs now to prevent any STD/HIV infection

Dr. Shyam Gupta
Dr. Shyam Gupta
Obstetrics and Gynaecology
Hello PATIENT to 1mg. There is some medicine for prophylactic but you need to see physician for prescription and better you check HIV status of both partner

hello, one of my frnd suffering with hiv infection from last 2yrs her cd4 is more than 470 and viral load is zero undetectable now she is using art medicines i have doubt that can we have to use art medicine in the whole life or can we stop it once we get viral load zero

Dr. Atula Gupta
Dr. Atula Gupta
Dermatology
You still need to be on ART even if the viral load is undetectable
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Disclaimer

Tata 1mg's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover everything about particular health conditions, lab tests, medicines, all possible side effects, drug interactions, warnings, alerts, etc. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.

Marketer details

Name: Zydus Cadila
Address: Zydus Tower, Satellite Cross Roads,Ahmedabad – 380015 Gujarat, India.

Vendor Details

Country of origin: India
A licensed vendor partner from your nearest location will deliver Virolfi 450mg Tablet. Once the pharmacy accepts your order, the details of the pharmacy will be shared with you. Acceptance of your order is based on the validity of your doctor's â„ž and the availability of this medicine.

In case of any issues, contact us

Email ID: [email protected]
Phone Number: 0124-4166666
Address: 5th Floor Tower - B of the Presidency Building, 46/4 Mehrauli Gurgaon Road, Sector 14, Gurugram, Haryana-122001, India

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Why we need a prescription?
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Prescriptions are complex documents. We proof read and recheck at various steps to provide you the right medication in the correct form and dose
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Most medicines cannot be sold without a valid prescription, as per the Drugs and Cosmetics Act, 1940 and Rules, 1945
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